RFK Jr is now seeing his dreams come true 😢

As @peterhotezmdphd.bsky.social and I sadly predicted, in #ScienceUnderSiege (bookshop.org/p/books/scie...)

🎶 It's beginning to look a lot like Scrippsmas 🎶 Season's Greetings, Merry Christmas and Happy Holidays to you and yours! 📸: @ucsandiego.bsky.social photographer Erik Jepsen

CRICK proudly on display at D. G. Wills bookstore in San Diego, where Michael McClure gave a reading in 2000. You can watch it in the link below; Crick appears in the background of the opening shots, his back to the camera. youtu.be/ih0vCt9w8Mw?...

What is the most highly cited paper in scientific literature? go.nature.com/48FcHtO

Yup. It has been incredibly painful watching the MAHA/Great Barrington Declaration/MAGA/anti-vaxx crew—RFK Jr, Bhattacharya, Oz, Makary, Høeg, Kulldorff, Prasad—deliberately dismantle public health, drive the return of deadly yet vaccine-preventable child diseases, & rip apart pandemic preparedness

"China will have abundant amounts of renewable energy for data centers, with fossil fuels as a backup. Meanwhile, the US marches boldly backward toward the past," writes H. Holden Thorp on Science's 2025 Breakthrough of the Year highlighting the rise of renewable energy. https://scim.ag/459EZKv

San Diego County Public Health Officials Recommend Hepatitis B Vaccine for Newborns

I'm only through the first couple of chapters but the first few sentences were enough to make me want to read it.

Marty Makary was asked this question the other week: "Where did AIDS come from?" His answer: "It may very well have come from a lab in Africa" How is this not a national scandal?

In June 2023, in an interview with New York Magazine, RFK Jr said “There are much better candidates than HIV for what causes AIDS” (H/T @drdemetre.bsky.social) 2023 🤯

Extremely alarming

Crispin G, the poodle, and Maggie waiting to go on a walk. She raised him from an 18 week old puppy. He is now almost 4 and obsessed with his dog mum.

youtu.be/ra0WKNhQZ0U Refreshingly, this pulls zero punches, and lands them squarely on the liars, grifters and frauds responsible for the lab leak hoax and the authoritarian persecution of science and scientists.

We are in Medieval times. 16 cases are linked to a church, which followed exposures at four schools last week. The outbreaks are threatening to cost the country its measles elimination status, which was earned in 2000 after vaccination efforts stopped the virus from spreading continuously. 🧪

#OTD in 1903, Marie Curie became the first woman to win a #Nobel Prize (#Physics). AND #OTD in 1935, her daughter Irene Joliot-Curie won the Nobel Prize in #Chemistry for the discovery of artificial radioactivity. They're the only mother–daughter pair to have both won Nobel Prizes. #WomenInSTEM

🚨I joined a remarkable group of physicians, epidemiologists, virologists, lawyers, & other public health experts to make this short video We cannot stand by & watch Trump, RFK Jr, & the MAGA/MAHA movement cause preventable sickness & death Please share far & wide, thanks

Hmm, I've read a pile of books this year but only one was published in 2025. Its a big 'un and I'm only through the first few chapters of it but its definitely worth reading....Crick. 🧪

Ditto.🧪

I run every day for 15 minutes and if I miss a day I add 15 minutes to the next day. This has truly been a game changer in my life. Tomorrow I’m supposed to run for three months…

A few years ago, Bill Nye the science guy debated creationist Ken Ham about evolution. The last question was "what would change your mind?" Bill Nye said "Evidence." Ken Ham said "Nothing can possibly change my mind about this." I think about that a lot.

I missed this from a couple of weeks ago, but if you're an NIH-funded investigator, please read. Peer review will exist to make things look legitimate, but can, and will, be over-ruled. Funding decisions, ultimately, will be done by political appointees. grants.nih.gov/news-events/...

Today is a dark day for American science and biomedicine. My comments in @nytimes.com www.nytimes.com/2025/12/05/h...

Important thread 🧵 on what eugenics is and isn’t from @jackiantonovich.bsky.social. Thank you, Jackie!

Franklin searching for the structure of DNA in 1952, with triple and quadruple strands, some of which exclude a helix. She was working with the wrong structure of the bases, so would be unable to find the right answer.

Humans took two routes to reach the ancient landmass Sahul about 60,000 years ago. Learn more in #ScienceAdvances: https://scim.ag/3XOFMwn

New York Times article on science funding with some depressing but familiar curves with interactive graphics. www.nytimes.com/interactive/...

Gosh, whoever could have predicted 🤨

Let's get this open.

My Yale medical school @thehowie.bsky.social @hmkyale.bsky.social Health & Veritas Podcast insights.som.yale.edu/podcasts/hea...

Now live, and thanks to @erictopol.bsky.social for organising this!

Here's an extract from my chat with @erictopol.bsky.social about Crick; this is about his involvement in 1980s work that helped lead to today's "AI"'s. Full video here: substack.com/home/post/p-...

Worth dropping into.🧪

In a potentially dramatic change to how it chooses what science to fund, NIH is ending a long-running practice at many of its institutes of establishing, and making public, a threshold peer-review score needed for a grant application’s approval. https://scim.ag/48ck2zu

"The Barmy Army, stunned into reckless late-afternoon abandon, began hurling beer trays at each other, creating a cascade of cardboard which was still only the third or fourth strangest thing happening at that given moment." #TheCricket

My interview with @dallasnews.com www.dallasnews.com/news/public-...

My comments with @cidrap.bsky.social @lizszabo.bsky.social www.cidrap.umn.edu/childhood-va...

Excellent. Love the comments.

Scientists tell Americans not to trust the CDC. Instead of a global leader in science, the CDC has devolved into “a propaganda machine for RFK Jr.'s fixed, immutable, science-resistant theories,” said @pauloffit.bsky.social. www.cidrap.umn.edu/childhood-va...

"In the first three months of 2025, the U.S. tallied 6,600 cases — four times last year's pace and 25 times 2023's. Several states are posting their highest case totals in a decade, and outbreaks from Louisiana to South Dakota to Idaho make clear this surge isn't regional. It's everywhere." 🧪

When you have a bias "vaccines cause autism" and you go looking for evidence to support that claim, you aren't doing science. You are simply feeding on your own BS.🧪

How awful. This is outright health disinformation, lying to the American people. Not only is there massive evidence showing no link between vaccines & autism, there’s not even a plausible mechanism based on what we’ve learned about the genetics of autism, some environmental exposures in pregnancy

I really hate it when scientists keep saying that “we need to rebuild trust in science,” because it implies that scientists are to blame for the mistrust rather than the millions of dollars of dark money that have funded political attacks on science in order to advance a far right agenda.

I left in 1987. The writing was already on the wall back then.