From conflict-fuelled cholera outbreaks and climate-driven dengue surges, to shrinking health budgets and the risk of Disease X, global health is already in the midst of a complex year. Here are the 6 top health threats experts are watching this year: bit.ly/4cenmOa

Following the dissolution of USAID what is emerging to replace it are exploitative one-sided deals proposing the exchange of aid dollars for sensitive health data, lack of reciprocal benefit and agreements that bypass multilateral frameworks. www.globalhealthunfiltered.com/blog/jn2u6d5...

Don’t deprioritize curiosity-driven research www.nature.com/articles/d41...

Justice sure took a long while… apnews.com/article/henr...

For those who saw the #ASH abstract but missed the actual publication suggesting IV Fe is safe in sepsis #HaemSky #Nephsky #NephJC

SNIPE is a widespread bacterial defence system that exploits the spatial organization of phage genome injection to specifically target viral DNA, distinguishing self from non-self in prokaryotic immune systems @nature.com @mitpress.bsky.social www.nature.com/articles/s41...

Review: Modulation of immune cells and metabolic reprogramming in efferocytosis www.nature.com/articles/s41...

High-throughput in vitro perturbation of stool/gut communities with 707 drugs suggests that nutrient competition is predictive driver of drug-induced microbiome restructuring. Post-drug recovery mainly driven by strain extinction+reseeding & resistance emergence uncommon www.cell.com/cell/fulltex...

Out Now! Gasdermins against intracellular bacterial pathogens #MicroSky

Unveiling hidden variables in stressed bacteria @cp-cellreports.bsky.social Review by @divyach.bsky.social and @maxencevincent.bsky.social www.cell.com/cell-reports...

the FDA have done an abrupt turnaround and after initially saying they wouldn't review Moderna's application to licence an updated flu vaccine for the fall they have NOW decided they will review the application 🤷‍♀️

Opinion: When a mere few months’ hiatus in UKRI funding opportunities imperils the futures of those without permanent posts, it only underlines the fragility of UK biomedicine, says a researcher #AcademicSky #Research ow.ly/q32l50Yhv9m

Another example of how mRNA vaccine technology is revolutionizing medicine in real time. Individualized mRNA vaccination triggered robust anti-tumor T cell responses in triple negative breast cancer leading to durable cancer remission. www.nature.com/articles/s41...

After initially rejecting Moderna’s application for review, the FDA will now consider the mRNA flu shot

During her PhD, Jenny found something unexpected: biofilm-deficient P. aeruginosa mutants were just as tolerant to antibiotics as the WT when grown in our cystic fibrosis lung model. But why? #MicroSky 1/n

'Cause it's haunted www.cnn.com/2026/02/13/s...

Adding first author of the preprint @grahamheieis.bsky.social

ICYMI Out Now! Addendum: ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro #MicroSky

"Ethical research requires that participant safety remains central, not subordinate to hypothesis testing....Vulnerability should never be seen as an opportunity to advance research at the expense of those it claims to serve." @natureportfolio.nature.com www.nature.com/articles/d41...

What does competition for iron look like for pathogens in different environments? We had the chance to contribute to this great paper looking at Salmonella in the gut with the Cunrath Lab (UoStrasbourg). Salmonella relies on siderophore exploitation at low pH url: academic.oup.com/microlife/ar...

#NatMicroPicks More than just pumps? 🦠💊 Bacterial efflux pumps not only block drug entry but also disrupt intracellular drug–target interactions by preventing repeated drug rebinding #MicroSky www.science.org/doi/10.1126/...

Out Now! Addendum: ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro #MicroSky

Hospital sink biofilms harbor multidrug-resistant gram-negative organisms capable of disseminating beyond the drain. This talk examines the microbiology, transmission pathways, and infection prevention challenges posed by sink-associated reservoirs in healthcare settings. youtu.be/rREHiXMX9W4

ICYMI: Out now! Out Now! Quantifying the real-world impact of antibiotic use and genetic determinants of resistance on gonococcal dynamics

Also universities.

www.nature.com/articles/d41... “They’re trying to use African children to prove a case for reducing vaccines in the US,” "That's problematic"... No...it's beyond the pale.

A newly sequenced 5500-year-old genome of Treponema pallidum rewrites the origins of syphilis, according to a new study in Science. Learn more: https://scim.ag/3Zpv2W2

New study in Cell Metabolism: Microbial metabolite FAD mobilizes adipocyte lipid remodeling to enhance cancer immunotherapy efficacy #microsky #microbiota #cancer @cp-cellmetabolism.bsky.social www.sciencedirect.com/science/arti...

Impact of databases on genomic survey of Salmonella antimicrobial resistance and virulence factor functional genes across the African continent www.biorxiv.org/content/10.6...

ICYMI: New Online! Heterogeneity, dynamics and organelle interactions of lipid droplets

Salmonella relies on siderophore exploitation at low pH #microLife by @ferrytin.bsky.social et al from Olivier Cunrath academic.oup.com/microlife/ad...

Excited to see this work on the cover of #MolecularCell. A massive, open #cryoEM #cryoET dataset capturing molecular organization inside intact cells, pushing what’s possible for #visualproteomics, method development, and computational reuse. Congratulations to the authors. ter.li/of4cgh

People think that anyone can do the job of communicating to the public but the fact is the profession of telling people stuff and doing it a way they understand, process, and engage with is actually an incredibly highly skilled job that many, many people lack the training and ability to do.

Personalized Antibiogram: A Novel Multi-Task Machine Learning Framework for Simultaneous Prediction of Antimicrobial Resistance Profile with Enhanced Detection of Carbapenem Resistance in Enterobacteriaceae https://doi.org/10.1093/cid/ciag027

A paper in Nature Microbiology presents Antimicrobial Single-Cell Testing, a large-scale live-cell imaging approach that quantifies bacterial killing in real time at single-cell resolution, which can predict treatment outcomes. go.nature.com/3Nwnez8 #microsky 🧪

Another recall. This time for Salmonella in chocolate bars manufactured in Raleigh N. Carolina. The products were distributed nationwide & sold as Mint Leaf bars under the Spring & Mulberry label. Food inspection has diminished under the Trump regime. Consumers become aware after illnesses emerge👇

At least 45 people in nearly two dozen states have been sickened with salmonella food poisoning tied to the Super Greens brand of diet supplement powder, federal health officials said. https://cnn.it/4qo5fK0

What is better than one? Two connected papers! #NewResearch S protein of Streptococcus pneumoniae activates PBP1a and coordinates with a wider GpsB-associated multi-protein complex to regulate peptidoglycan remodelling and cell division. #MicroSky 🦠 www.nature.com/articles/s41...

Precious Matsoso, a public-health official based in Pretoria, South Africa, brokered the world’s first pandemic-preparedness treaty after years of hard-fought negotiations. She’s part of Nature’s 10 for 2025. 🧪

How can we tell whether an antibiotic eradicates an infection? Researchers from the @biomedizin.unibas.ch, at the @unibas.ch, present an antimicrobial single-cell microscopy-based method that measures antibiotic lethality in individual bacteria. 🔗 doi.org/10.1038/s415... @natmicrobiol.nature.com

#NatMicroPicks bacterial amino acid metabolism affects cancer progression 🦠🦀🐁 Bacteroides asparaginase lowers intestinal asparagine levels and drives colorectal tumor progression #MicroSky www.cell.com/cell-host-mi...

The limitations of small molecule and genetic screening in phenotypic drug discovery

#microsky 😳 www.cell.com/cell-host-mi...

Our recent paper in npj Antimicrobials and Resistance is a great example of scientific serendipity: after staring at thousands of bacterial growth curves over many studies, we started wondering whether the curve shapes themselves carry mechanistic information 1/9 🦠🧪 www.nature.com/articles/s44...

We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.