Deadline tomorrow! Explore advances in telomere biology and its involvement in homeostasis and disease in EMBO Workshop "Telomere function and maintenance in health and disease" in Lazise, IT, 25–30 May 2026. https://meetings.embo.org/event/26-telomere #EMBOTelomereMaintenance #EMBOevents 🧪

S. pombe telomerase RNA: secondary structure and flexible-scaffold function https://www.biorxiv.org/content/10.1101/2025.02.22.638514v1

We have now published our secondary-structure model for the 1212 nt 𝘚. 𝘱𝘰𝘮𝘣𝘦 telomerase RNA, derived largely from bioinformatic and phylogenetic analyses of genomic data. (1/2) www.tandfonline.com/doi/full/10....

“Put another way, punishing campuses by cutting health research funding would destroy the equivalent of one-quarter of annual gross domestic product in the US.”

JAMA Forum on the proposed NIH budget… jamanetwork.com/journals/jam...

"If the proposal is enacted, Americans today and tomorrow will be sicker, poorer, and die younger” an $18 Billion cut Only 3 NIH Institutes will remain in place, and even they will have their funds markedly reduced www.statnews.com/2025/05/30/n...

A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon. amazon.com/gp/new-relea...

In St. Louis, the sirens to warn people of a tornado threat were not activated by the City Emergency Management Agency before a deadly tornado hit on Friday, and a backup to activate the mechanism that is operated by the Fire Department was broken.

More context: Our tracker (grant-watch.us) currently lists 877 terminated NIH grants. We have 820 rows in the tracker, but some rows list multiple grants. As of yesterday, NIH RePORTER listed 807 NIH grants specifically at Harvard. So we're looking at over 1600 formally terminated NIH grants now.

The USFWS has announced that it killed the breeding male of the Hail Canyon pack in New Mexico. The wolf, a 5 yr old dad named Viento, was the breeding male of a family of wolves that includes Slides - the Mexican gray wolf fostered from the WCC into the wild in 2023.

Measles in the US, update —712 cases, 11% hospitalized, 3 deaths, 97% cases are unvaccinated —Now in 24 states —Actual cases must be multiple thousand to align with the number of hospitalizations and deaths reported www.cdc.gov/measles/data... www.cbsnews.com/news/measles...

Application deadline extended to Apr 15 for this summer's #Yeast #Genetics & #Genomics course at @cshlaboratory.bsky.social July22 - Aug12! Get a comprehensive education in all things yeast, from classical genetics through up-to-the-minute genomics. Don't miss out! meetings.cshl.edu/courses.aspx...

The Pacific Northwest Yeast Club is holding their annual meeting on June 20th, 2025 in beautiful Vancouver, Canada! There are only 100 spots and registration is open now: www.pnwyc.net

This!!! I hope someone in Washington is listening www.wsj.com/tech/biotech...

Looking at grant funding time for all years from 2015-2025 Here is the graph for new and competitive renewal grants (dollar amounts normalized by the overall NIH grant budget for each year_ 1/2

I don’t think the country understands the nuclear bomb that has hit and destroyed Americas future. Our competitiveness globally was threatened - it is now guaranteed to dwindle to irrelevance. The future is based on science and technology. By the time they realize the damage, it will be too late. AR

Tragic, infuriating news. Mexican gray wolf Ella, whose travels captivated a nation just last week, was found dead in New Mexico. The U.S. Fish and Wildlife Service has indicated that the cause of Ella’s death is under investigation.

🧪⚛️ If you want to sign a petition to protect the NIST Atomic Spectroscopy Group, here's an opportunity: www.change.org/p/oppose-the... Hat tip to @nanoscaleviews.bsky.social for sharing this.

The destruction of American science continues apace. Early career people are the most likely to be seeking to leave. One of my about-to-graduate PhDs is seriously considering a job offer in Germany, even though it would involve lower pay. www.nature.com/articles/d41...

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

I've reviewed 10 consumer-facing companies that are in the business of promoting longevity and healthspan erictopol.substack.com/p/the-busine... Open-access, in the new edition of Ground Truths

Texas measles update today 309 cases; 40 have been hospitalized (<-which means there are far more than 300 cases diagnosed) www.dshs.texas.gov/news-alerts/...

ATTENTION If you are someone (or know someone) who is enrolled in an NIH-funded clinical trial that has been disrupted by grant uncertainties or terminations, please DM me. THANK YOU!

New SGD paper! Saccharomyces Genome Database: advances in genome annotation, expanded biochemical pathways, and other key enhancements academic.oup.com/genetics/art...

90% of people diagnosed with pancreatic cancer die from the disease. That's why the medical community is excited about the results of a small trial in which nearly half of the pancreatic cancer patients who received an mRNA vaccine for the disease remained relapse-free three years later.

THIS IS INCREDIBLE! Cohen Children’s Medical Center has confirmed that it has successfully ELIMINATED sickle cell disease from Sebastien Beauzile, using the groundbreaking genetic treatment Lyfgenia. He has made HISTORY by becoming the FIRST in New York to be CURED of sickle cell anemia! 🧪🧵⬇️

We have a winner...

Stand Up For Science 2025 in Philadelphia Pennsylvania

Hey Philly people, come to the Stand Up For Science rally tomorrow at City Hall! I'll be speaking around noon! There are rallies all over the country, you can find your local rally here standupforscience2025.org/local-event-...

Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies. bit.ly/43kHcCV

A rapid CRISPR test could completely transform the diagnosis of Pneumocystis pneumonia, a life-threatening fungal infection. Today it typically requires invasive bronchoscopy, but this test enables rapid detection from blood or throat swabs. www.jci.org/articles/vie...

In a preprint published today, we are excited to report the secondary structure of the 1212 nt fission-yeast S. pombe telomerase RNA, TER1, and its roles in the physicofunctional organization of this massive, flexible enzymatic RNP complex. www.biorxiv.org/content/10.1...

A worsening measles outbreak has taken root in Texas, sickening two dozen and hospitalizing nine on the western edge of the state, where childhood vaccination rates have dwindled in recent years.

JUST IN: Federal judges orders HHS, CDC, and FDA to restore “by no later than 11:59 pm” today their websites and datasets to pre-January 30th status. storage.courtlistener.com/recap/gov.us...

AMAZING! A GROUNDBREAKING sickle cell disease treatment has been APPROVED for NHS use. Exagamglogene (exa-cel) SUCCESSFULLY edits the faulty gene in a patient’s OWN stem cells. Researchers concluded there was a functional cure in 97% of trial participants that received it! Let’s talk about that! 🧪🧵⬇️

The Trump admin has cancelled the panels that approve NIH grants, & is also banning scientists from communicating with the public, attending conferences, and hiring. NIH is the largest funder of biomedical research in the world. This will severely halt the development of many lifesaving treatments.

98% of microplastic particles (MP) in bottled water are smaller than 20 μm, which are much more likely to get thru the GI tract to blood and organ tissue. Municipal tap water was higher in MP than 8 of 10 bottled water brands journals.plos.org/water/articl...

An international research team has successfully drilled and retrieved a 9,186-foot-long (2,800-meter-long) ice core from Antarctica that dates back 1.2 million years. The sample extended so deep that it reached the bedrock beneath the Antarctic Ice Sheet. Read more: cnn.it/3Wekfgo

Twenty big cats, including a half-Bengal tiger and four cougars, died at a sanctuary in Washington State after becoming infected with bird flu, according to the facility’s director. “We’ve never had anything like it.”

🚨The deadline to apply for Lehigh University’s Biological Sciences PhD program is just a few weeks away! Are you (or do you know) an amazing undergrad, post-bac, or master’s student passionate about science & ready to thrive in a supportive, interdisciplinary environment? Apply here!👉bit.ly/3VwZL29

🚀 Excited to share that my postdoc work with @adernburg.bsky.social on a Piezo-dependent meiotic checkpoint in C. elegans has just been published in Science doi.org/10.1126/scie... Here's a summary thread, or a “Skydive” (coined by @harmitmalik.bsky.social‬), of the key findings in this work 🧵⬇️1/10

The world’s oldest known wild bird, a 74-year-old Laysan albatross named Wisdom, is expected to welcome another baby chick in the coming months, astonishing scientists who have been tracking her since the Eisenhower administration. nyti.ms/4f7VadN

One person has died and 39 people have become ill in an E. coli outbreak linked to organic carrots, federal regulators said on Sunday.