It’s that time of year again~ day one of pumpkin month is wolf ! #weretober

Your ONLY CHANCE to get my tutorials BOOKS is on KICKSTARTER on a SECRET DATE in EARLY 2026, ONLY by joining the mailing list, which is ONLY OPEN for the next 40 HOURS this month! send "Add me, Lorenzo!" to ‬[email protected] joined‪ our mailing lists before? You’re on it!‬

「 #Weretober2025 」 //Day 01// - Wolf -

Well, seems @kerun.bsky.social got a role in an anime and didnt tell me about it.

September 30 ... October 1

The Hollywood community was quick to condemn the AI-generated “actress” Tilly Norwood and its creators, with SAG-AFTRA saying, "creativity is, and should remain, human-centered." bit.ly/4pTxa4E

Once again, this perfect @zeboydgames.bsky.social post comes to mind:

You have to hand it to the generals. Unlike so many other people in this country, they know how to conduct themselves in public. They know they are supposed to be apolitical. So they greeted Trump's political speech with silence. And you could have heard a medal drop when Pete Hegseth finished.

I've had to call this piece of shit almost daily to try and help stop censorship acts. He's clearly not going to listen, so I expect everyone else to make an effort.

The Cartoon Network Hotel in Pennsylvania will close down starting on January 1st. It will then rebrand to Dutch Wonderland Inn in March.

My legs are thoroughly worked. 1020 lbs as a fuck it set

If Pokemon Go could have a New Game+ or Prestige option What would that have to look like for you to use it?

i forgot i should probably post the stuff i draw

Happy late #biceptember, my fellow soy beans~ >;3c Go get your pump game on~!

It’s time to get spooky

Noelle Holiday 🥶❄️

Video seeing what wild things stunt people can do with fire: cool! What talented people! Same video but the stunt person is scrabbling around and jumping through fire to pick up money: holy wow, that’s unpleasant vibes!

I wish the dystopian world we live in was just a little bit less profoundly dark.

I'm always tempted to "send help" to people on Facebook (like literally the minimum $ amount) just so I can add the message "May you one day find your brain"

Trump and Republicans made devastating cuts to Medicaid and plan to let vital ACA subsidies expire. Millions on Medicaid will lose coverage. Millions on ACA plans could see premiums rise by as much as 75%. Every lie they tell about a shutdown is meant to cover this up.

It's absolutely insane that work makes us file our own work order tickets. No. I do not know which service department "my computer server is out of space" goes to? Is it "Workstation Issue" "Network access" Or maybe

Masked men posing as ICE agents are kidnapping and assaulting women—taking advantage of the chaos and fear Trump's detention and deportation policies have fostered. Guest writer Cammy Pedroja exposes how Trump’s fear-driven immigration crackdown is endangering immigrant women.

Feeding all the babies~~ 🦊🧡🧡🧡 For the lovely @fayanna.bsky.social , thank you!! <3

Please stop using the Emperor's New Clothes metaphor for Donald Trump. It conjures images that are truly terrifying.

Once again, the moderate position is for ICE to be abolished and Border Patrol to be gutted, and massive civil rights prosecutions leading to prison time. Anybody running on anything less is kicking the can down the road.

some zelda doodles on paper for a change

Oh! It #rabbitday!!! How can something so small be so full of rage?

Ok, by popular demand (and let's be honest. I wanted to do this anyway 👀), #biceptember part 4! 💪✨ Thanks again for all the encouragement! I tend to hold back on this sort of thing, so it's nice to indulge a bit. #rabbit #gymfur #furry #furryart #rebelle #watercolor #musclegrowth

👁️

*sweep sweep* ah I see youve noticed her sweeping leaves off the soft earth

rotten star

heavierrrr 🫴🏼

Scribbly thing

where time flows

Like Kaiba bro that's a dead child 😭😭😭😭

You can read all this and more here: • www.bbc.com/news/article... • www.globenewswire.com/news-release... • www.uniqure.com/programs-pip... • www.sciencealert.com/breakthrough... • www.statnews.com/2025/09/24/h... • www.biospace.com/drug-develop... • www.theguardian.com/science/2025...

With treatment, people will be able to work and live independently for significantly longer, researchers said, and the dramatic impact of the therapy raises the possibility that it could prevent symptoms occurring if given at an earlier stage.

The company hopes to submit the drug for approval in the U.S. early next year and conversations with authorities in the UK and Europe will start next year as well.

There were also clear indicators in the brain that neurons were being spared, with levels of neurofilaments (a sign of cell death) being significantly lower in the treatment group.

the high dose of the drug had an average of 75% slowing of the progression of the disease, based on tests of motor function, cognition and the patients’ experience of day-to-day life.

for building mutant huntingtin. This results in lower levels of mutant huntingtin in the brain. Results from the trial, involving 29 patients treated in the UK and US, have been released by the company uniQure, although the full details are yet to be published. Three years after treatment, those on

where it becomes active. This turns the neurons into a factory for making the therapy to avert their own death. The cells produce a small fragment of genetic material (called microRNA) that is designed to intercept and disable the instructions (called messenger RNA) being sent from the cells' DNA

DNA. This is infused deep into the brain using real-time MRI scanning to guide a microcatheter to two brain regions - the caudate nucleus and the putamen. This takes 12 to 18 hours of neurosurgery. The virus then acts like a microscopic postman- delivering the new piece of DNA inside brain cells,

The goal of this treatment is to reduce levels of this toxic protein permanently, in a single dose. The therapy uses cutting edge genetic medicine combining gene therapy and gene silencing technologies. It starts with a safe virus that has been altered to contain a specially designed sequence of

huntingtin gene. As I said above, if one of your parents has Huntington's disease, there's a 50% chance that you will inherit the altered gene and will eventually develop Huntington's too. This mutation turns a normal protein needed in the brain -the huntingtin protein- into a killer of neurons.

inactivating the mutant protein that causes Huntington’s. It is delivered to the brain in a single shot during a 12- to 20-hour surgical procedure. A single dose is expected to last for a patient’s lifetime. To break this down: Huntington's disease is caused by an error in part of our DNA called the

Those with a parent with Huntington’s have a 50% chance of developing the disease, which has been incurable, until now that is. The therapy, known as AMT-130, successfully slowed the progress of the disease by 75% in patients after three years in trials. How does it work? AMT-130 works by