Check out our new biosensor technology to study DDR kinase signaling: ProKAS. We combine: -proteomics -engineered peptide sensors -a new concept of amino acid barcodes ProKAS tracks kinase signaling with spatial resolution and produces highly quantitative data. Just published today: rdcu.be/ePNo0

A significant conceptual advance in the field of DNA recombination… great work by the labs of @brookscrickard1.bsky.social and Michelle Wang

Honored to receive an Outstanding Poster Award at the Protein Science Symposium! Huge thanks to the @weillinstitute.bsky.social and @weillcornell.bsky.social for an amazing event—and of course, big shoutout to the @smolka-lab.bsky.social for making the poster results possible!

We are counting down the days to our Protein Science Symposium on June 10-12! Thrilled to be hosting our colleagues from WCM @weillcornell.bsky.social as well as keynote speakers Dr. Christopher Lima @christopherdlima.bsky.social and Dr. ‪Jin Zhang @jinzhanglab.bsky.social

New preprint from the lab: ATM controls fork processing and restart, and the PPM1D phosphatase is needed to properly balance this action of ATM. Congratulations to @yitingcao.bsky.social @yingzhengwang.bsky.social and Jumana Badar. www.biorxiv.org/content/10.1...

Double award to the fantastic graduate student @mateuszwagner.bsky.social …

Devasting that clinical trial for Jim's PediaFlow baby heart pump is on hold due the stop on all DOD funding at Cornell. Funded by DOD CDMRP, Congressionally Directed Medical Research Programs, yet White House stopped Congress funds #ResearchSavesLives #Standup4Science youtu.be/a7aUBvBcPV4

🚨🧪 Are you a researcher affected by the recent cancellation of federal grants and contracts at Columbia University? I'm working on a story for @Nature.com. If you want to chat, your identity will be kept private. Signal: humbertobasilio.24 Email: [email protected] Repost please!

Our preprint is now published www.science.org/doi/10.1126/...

Applications are open for the Weill Institute Emerging Scholars Symposium @ Cornell! Senior PhD students and, now, postdocs interested in networking & presenting their work in cell & molecular biology should apply by April 14, 2025. Please repost! wicmb.cornell.edu/emerging-sch...

Senior graduate students and postdocs, here is a great opportunity to network, showcase your science and get to know Cornell and beautiful Ithaca! Please repost.

My first-author paper on uncovering a non-canonical Tel1 motif using phosphoproteomics has been published in JBC! Amazing to work with @rainshj.bsky.social using both untargeted and targeted mass spectrometry. Check it out: doi.org/10.1016/j.jb...

Very interesting work by the @zhalab.bsky.social showing why Ku is essential in human cells

In this new paper we find that Tel1 kinase (yeast ATM) targets D/E-S/T motifs… more prevalent than S/T-Q! Mec1 (yeast ATR) can’t target D/E-S/T, so we think D/E-S/T targeting allows Tel1 functional specialization. A mutation in Tel1 makes it only target S/T-Q… and cells become CPT sensitive.

Happy to share a new work from the lab on how DNA damage checkpoint can be down-regulated. rdcu.be/d5o3E. Congrats to all authors at @mskcancercenter.bsky.social and our Weill BCMB student @tzippora.bsky.social. gradschool.weill.cornell.edu/bcmb-allied-...

Excited to share our preprint reporting a completely new approach to study kinase signaling: ProKAS. ProKAS is based on a tandem array of peptide sensors with barcodes for multiplexed, spatial and kinetic applications. We applied it to DDR kinases. Please share. www.biorxiv.org/content/10.1...

Great “tools of the trade” piece by Xiaofu Cao in Nat Rev Mol Cell Biol about her recent paper exploiting cell cycle-dependent phosphorylation to make a conditional protein relocalization tool! ToT piece: rdcu.be/d0Utp Original paper (@naturecellbiology.bsky.social): www.nature.com/articles/s41...