Benjamin Broomfield
@benjbroom.bsky.social
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Immunologist & PhD Candidate @WEHI-research in Melbourne, Australia
reposted by
Benjamin Broomfield
Cyril Seillet, PhD
4 months ago
🎓 PhD positions available @MonashUni Join our lab to explore how neurons and immune cells shape gut immunity! 🧬 Single-cell RNAseq 🔬 3D imaging 🧠 Neuro-immune interactions 👥 Great mentoring & collaborations Apply now 👉
tinyurl.com/Seilletlab
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Understanding the neuroimmune regulation of innate immunity | Supervisor Connect
https://tinyurl.com/Seilletlab
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reposted by
Benjamin Broomfield
WEHI (The Walter and Eliza Hall Institute of Medical Research)
4 months ago
A landmark WEHI-led study has uncovered how our daily food choices are having an immediate effect on our gut health. Brilliant research led byDr Cyril Seillet and Dr Le Xiong, that could help pinpoint
#chronicinflammation
at the source. Now published in Immunity.
www.wehi.edu.au/news/fast-fo...
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reposted by
Benjamin Broomfield
Lauren Howson
5 months ago
🚨 New publication alert! 🚨 Thrilled to share our latest research out today in
@jclinical-invest.bsky.social
! This work is another great outcome of my amazing clinical research partnership with first author Samantha Chan and RMH.
@wehi-research.bsky.social
#immunology
#research
#JCI
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JCI - A dominant-negative IFNGR1 variant reveals broad immune cell sequestering of IFN-γ
https://www.jci.org/articles/view/186799
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reposted by
Benjamin Broomfield
Joanna Groom
5 months ago
Excited to have our latest research published in
@jem.org
this week and also highlighted by
@natrevimmunol.nature.com
@wehi-research.bsky.social
@benjbroom.bsky.social
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reposted by
Benjamin Broomfield
WEHI (The Walter and Eliza Hall Institute of Medical Research)
5 months ago
Future vaccines a step closer. Research from
@groomlab.bsky.social
,
@benjbroom.bsky.social
and team use novel approach and mRNA tech to boost stem cell-like memory CD8+ T cells after vaccination. Published in
@jem.org
www.wehi.edu.au/news/vaccine...
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reposted by
Benjamin Broomfield
Journal of Experimental Medicine
5 months ago
Our May issue is here!
rupress.org/jem/issue/22...
Cleary et al. (
doi.org/10.1084/jem....
) developed a new intravital technique for imaging pulmonary lymphatics. The cover depicts a 3D projection of a whole lung lobe with lymphatics (purple) and smooth muscle (white) labeled.
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reposted by
Benjamin Broomfield
Journal of Experimental Medicine
5 months ago
@benjbroom.bsky.social
et al.
@groomlab.bsky.social
show that transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection.
rupress.org/jem/article/...
📘 In JEM
#Immunology
Collection:
rupress.org/jem/collecti...
#AAI2025
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reposted by
Benjamin Broomfield
Journal of Experimental Medicine
5 months ago
This year's JEM
#Immunology
collection highlights recent findings in the field of B cells, CD8+ T cell stemness, priming and differentiation, CD4+ T cell heterogeneity, autoimmunity, lymphatic immunophysiology and innate immune signaling. 👉
rupress.org/jem/collecti...
#AAI2025
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reposted by
Benjamin Broomfield
Le Xiong
5 months ago
Thrilled to share our work now published on
@cp-immunity.bsky.social
. Big thanks to our collaborators. Here we show that short-term High-Fat diet impairs ILC3 functions in producing IL-22 through microbiota-dependent and-independent mechanisms.
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reposted by
Benjamin Broomfield
WEHI (The Walter and Eliza Hall Institute of Medical Research)
6 months ago
You’re invited! Celebrate the Day of Immunology at WEHI on 29 April. 🔹Hear from top scientists 🔹Discover the new Snow Centre for Immune Health 🔹Go behind the scenes with a lab tour 🔹Enjoy morning tea & meet the team Register now -
www.immunology.org.au/events/-ASI-...
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Happy one week of my
@jem.org
paper! Our work from the
@groomlab.bsky.social
at
@wehi-research.bsky.social
identifies using early IFN-I blockade alongside mRNA vaccination to direct CD8+ T cell positioning in the lymph node to drive Tscm cell differentiation and enhance vaccine protection
6 months ago
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reposted by
Benjamin Broomfield
Ivan Zanoni
6 months ago
#WeekendRead
!
#InterferonFriendOrFoe
!
@benjbroom.bsky.social
@groomlab.bsky.social
&co show
@jem.org
that transient type I IFN inhibition upon LCMV infection or a mRNA vaccine boosts stem-like memory CD8 T cells by altering their location within the draining lymph node, potentiating virus protection
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Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection | Journal of Experimental Medicine | Rockefeller University Press
Broomfield et al. demonstrate that early type I interferon blockade alters CXCR3 chemokine regulation and cell location to promote an antigen-dependent CD8
https://rupress.org/jem/article/222/5/e20241148/277313/Transient-inhibition-of-type-I-interferon-enhances
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reposted by
Benjamin Broomfield
Joanna Groom
7 months ago
Very excited our work out in
@jem.org
“Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection”
@wehi-research.bsky.social
led by talented (and determined) PhD student
@benjbroom.bsky.social
Thread below.
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reposted by
Benjamin Broomfield
Journal of Experimental Medicine
7 months ago
@benjbroom.bsky.social
et al.
@groomlab.bsky.social
show that early type I interferon blockade alters CXCR3 chemokine regulation & cell location to promote an antigen-dependent CD8+ T cell transition of precursor of exhausted T cells to stem cell–like memory CD8+ T cells
rupress.org/jem/article/...
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So lucky to be in a lab that does great science AND indulges in a weird photoshoot 🫶 Happy holidays!
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9 months ago
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