Nature MS#2 today - More interesting Promethion-powered science from Dr. L Lynch & colleagues - butter-based HFD suppresses NK/CD8 anti-tumour immunity via acylcarnitines, while palm oil fares better in obese mice!🧪 www.nature.com/articles/s42...

More intriguing Promethion-powered research from Dr. X Liu & colleagues at University of Kentucky - PLK1 phosphorylation of PDHA1 rewires metabolism in lung cancer; DCA + onvansertib show synergy in mice! 🧪 www.nature.com/articles/s41...

PhD Alert! 😍 Our lab is hiring a PhD student to study how shrews shrink in winter and grow in spring. Yes, you read that right! tinyurl.com/shrinkingshr... Join us at the @mpi-animalbehav.bsky.social, study a super cool animal, and join the @imprs-qbee.bsky.social community! DM me for questions!

"Now an extraordinarily successful scientific research system — one that took decades to build, has saved millions of lives and generated billions of dollars in profits for American companies and investors — is being dismantled before our eyes."

We are looking forward to hearing from Dr. Teresa Zimmers today in San Antonio.

In his Commentary, Neil Metcalfe examines why it can be hard to detect trade-offs between two activities or processes competing for energy, despite energy supposedly being a limiting resource journals.biologists.com/jeb/article/...

Well said.

NEW Adrenergic stimulation as a means to determine in vivo brown adipose tissue thermogenic capacity ✒️ Lindsund et al. 🔗 doi.org/10.1139/cjz-...

🚨JOB ALERT🚨 Come join me and my supportive colleagues at The Ohio State University! The Department of Neuroscience 🧠 is hiring a tenure-track faculty member (open rank). We will begin reviewing applications on 9/14/25. Apply here👇, and please share! careers.wexnermedical.osu.edu/search/jobde...

More impactful Promethion‑powered research from Dr. O MacDougald & colleagues at University of Michigan - FGF21 + sTGFBR2 gene therapy eases lipodystrophic insulin resistance, temperature‑dependently! 🧪 insight.jci.org/articles/vie...

More forward looking Promethion powered science from Dr. M Hjorth & colleagues at University of Oslo - decorin deficiency leaves adiposity, glucose tolerance & VO₂ unchanged in mice. 🧪 physoc.onlinelibrary.wiley.com/doi/10.14814...

More captivating Promethion powered research from Dr. C Martin & colleagues at Université Paris Cité - striatal astrocytes tweak behavioral flexibility & whole body metabolism in obesity. 🧪 www.nature.com/articles/s41...

More thrilling Promethion‑powered science from Dr. R Kuhre & colleagues at University of Copenhagen - CagriSema slashes rat weight by cutting intake while preserving energy output! 🧪 www.nature.com/articles/s42...

🔥 Hot of the press our printed program big thanks to @albamena.bsky.social & our sponsors @eassociety.bsky.social @dfg.de Menarini Group @sablesys.bsky.social TSE Systems Agilent Technologies @lucidscientific.bsky.social Biosfer Teslab More info: eas-elc.org

Congratulations to our distinguished awardees at the inaugural #asiposebiology conference: Bruce Spiegelman, Yu-Hua Tseng, and Paul Cohen. Your work continues to inspire and shape the future of our community #ABC2025 @adiposebiology.bsky.social @sablesys.bsky.social @spiegelmanlab.bsky.social

For those unaware, last year I needed to leave vet school at the RVC. Tuition rates were increasing & my student loans couldn't keep up. I created a GoFundMe in hopes to raise the money #VetMedSky #MedSky #VetMed @academic-chatter.bsky.social #AcademicChatter 🧪🌎🐦🦇👩‍⚕️🐶 gofund.me/9164dd5c

Interested in energy allocation - how an animal partitions its energy budget between simple survival, thermoregulation & activity? It's easy to measure with the Promethion metabolic phenotyping system! Read more here 🧪: medium.com/@JohnLighton...

1/3 Some Promethion users just received a legacy metabolic phenotyping competitor’s letter full of misinformation. Curious: Why would they risk their reputation that way? We've replied with what matters: solid physics, data & science. Link in next post. 🧪

Some Promethion users just got a competitor’s letter full of disinformation. We’re amused they’d risk their reputation that way. We’ll reply with what matters: solid physics, data & science. Stay tuned! 🧪

I realize I'm quote-skeeting a skeet that quotes me, but the message is as important as it is sad.

What's that awful smell? It's the rising stink of salesman's sweat coming from one of our metabolic phenotyping competitors 🤨🤣

12 examples of how developmental biology research led to fundamental discoveries for biomedical research. There are many more! Download ppt & jpg versions on @socdevbio.bsky.social website. Use & modify as needed. Poster formats are also posted to print & hang in your lab!

Just ONE WEEK until the #AdiposeBiology Conference! See you in Montreal! Check our website for details and the full schedule: adiposebiology.com #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social

Science is effectively dead in the US for at least the next 3½ years, and will then take another several years to even get started again. Canceled research doesn’t just uncancel itself, and scientists who find opportunity elsewhere won’t just come flocking back. The damage is generational.

Every reputable expert I know considers mRNA vaccine technology to be one of the most revolutionary advances in medicine in our lifetimes. Its inventors won the Nobel Prize in 2023. Shutting it down now is pointless self-harm to humanity.

More significant Promethion powered research from Dr. Z Song & colleagues at Guangxi University - adipose CIDEC knock down boosts insulin sensitivity & energy expenditure via ATGL PPARα! 🧪 www.sciencedirect.com/science/arti...

More noteworthy Promethion-powered science from Dr. Y Zhu & colleagues at Hong Kong Polytechnic University - chronic low dose 6PPD subtly alters energy balance during obesity progression! 🧪 www.sciencedirect.com/science/arti...

More pioneering Promethion powered research from Dr. R Arrojo e Drigo & colleagues at Vanderbilt University - multi scale microscopy maps spatial glucose flux in hepatocytes in vivo. 🧪 www.nature.com/articles/s41...

For those select few who need a Venus of Willendorf candle to brighten their lives, I have good news and bad news. The good news is that such a candle exists. The bad news is it is only to be found on San Juan Island in Washington state.

More provocative Promethion‑powered science from Dr. S Diano & colleagues at Columbia University - DRN MC4R‑GABA neurons co‑regulate feeding & anxiety! 🧪 www.sciencedirect.com/science/arti...

More innovative Promethion‑powered research from Dr. C‑M Wong & colleagues at Hong Kong Polytechnic University - Epigen gene‑therapy restores glucose homeostasis in obese & diabetic mice. 🧪 www.cell.com/molecular-th...

Your periodic PSA that Sable Systems International is now manufacturing Promethion systems in the EU! Sable Systems Europe has been offering local support for our EU & British customers for many years, & we are backing this up with production - & can ship from the EU world-wide.

More revealing Promethion‑powered research from Dr. L Geng & colleagues at the Chinese Academy of Sciences - betaine acts as an exercise‑mimetic delivering geroprotection! www.cell.com/cell/abstrac...

Anti-vaxxers like to call people who promote vaccination “arrogant”. I ask you, what could be more arrogant than thinking that a person with zero training or experience in any related field knows more than tens of thousands of scientists and healthcare workers? Or is that just insanity?

Great job cutting cancer research, everybody! This is so much fun! -Russell Vought

More promising Promethion powered research from Dr. T Bengtsson & colleagues at Karolinska Institutet - GRK biased β agonists burn fat & lower glucose in obesity models. www.cell.com/cell/fulltex...

More fascinating Promethion powered science from Dr. J Tam & colleagues at Hebrew University of Jerusalem - blocking renal GLUT2 resets systemic metabolism without hyperglycemia! 🧪 www.sciencedirect.com/science/arti...

More groundbreaking Promethion powered research from Dr. X Xie & colleagues at Tianjin Medical University - palmitate blocked PRDX1 worsens NASH, hinting at redox targeted therapy. 🧪 www.nature.com/articles/s41...

More insightful Promethion‑powered science from Dr. U Wankhade & colleagues at Arkansas Children’s Nutrition Center - maternal high‑fat diet re‑programs offspring adiposity via heat‑shock proteins! 🧪 www.sciencedirect.com/science/arti...

More illuminating Promethion‑powered research from Dr. J Abubaker & colleagues at Dasman Diabetes Institute - elevated IGFBP4 links obstructive‑sleep‑apnea mice to cognitive decline! 🧪 www.preprints.org/manuscript/2...

More compelling Promethion powered research from Dr. J McCarthy & colleagues at University of Kentucky - microRNA 1 loss rewires skeletal muscle pyruvate metabolism, limiting metabolic flexibility. 🧪 www.sciencedirect.com/science/arti... (PubMed)

More exciting Promethion powered science from Dr. E Chang & colleagues at University of Chicago - microbiome transplant mismatches trigger lasting metabolic & immune shifts! 🧪 www.cell.com/cell/abstrac...

More intriguing Promethion powered research from Dr. R Pereira & colleagues at University of Iowa - deleting ATF4 in brown fat eases diet induced insulin resistance without weight gain! 🧪 academic.oup.com/endo/article... (Katalog plus)

Today, 1,152 NAS members/Nobel Laureates (as private individuals) sent a letter to Congress regarding the cuts to science being proposed by the Administration, and currently going through the House and Senate Appropriations Committees. tinyurl.com/5n7y7853 @standupforscience.bsky.social

As a scientist who studied animal behavior, this is extremely alarming. There is no way to test behavior/cognition in an organoid. If you could, that organoid would be conscious & deserving of protections as well. Either neuroscience should be forbidden forever or these sacrifices are necessary.

1/10 Are you following the NIH’s push to reduce or even eliminate animal models? As a UCLA PhD in comparative physiology with 100+ peer reviewed papers, I have thoughts. Read on.

Your periodic friendly reminder that Sable Systems now manufactures & ships its Promethion metabolic & behavioral phenotyping product line in & from Europe as well as the United States. Other product lines will follow in due course. 🧪 Service is our only goal 😎

As life sciences research becomes enmeshed in the age of AI, real experimental data are more valuable than ever. Read more in this month's Editorial. www.nature.com/articles/s41...

Are you a top US-based scientist wanting to relocate to Australia? We are now calling for formal applications from both Australian and non-Australian citizens based in the US whose work is internationally recognised as exceptional. 📅 Applications close: Aug 29, 2025 🔗 science.org.au/gtap/?utm_so...

Climate change is fueling catastrophic floods, but Trump's administration is cutting the tools we need to fight back. NOAA labs, NASA satellites, FEMA grants & local warning systems are on the chopping block. Result? Communities will be caught unprepared when disaster strikes. zurl.co/vUw4Z