Just in case anyone needs to hear it: - Acetaminophen does not deplete glutathione unless you are taking toxic doses of it - MTHFR variants don't prevent you from being able to use folic acid - We don't know how folic acid works to prevent neural tube defects (NTDs); we simply know it does. (1/7)

Microbes without borders: uniting societies for climate action @femsjournals.bsky.social Microbiol Ecol by @jaytlennon.bsky.social et al @leonorabit.bsky.social @vscooper.micropopbio.org @gilbertjacka.bsky.social academic.oup.com/femsec/artic...

This is my shocked face /s

Please share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment. The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP jasonjwilliamsny.github.io/grfp2025/

Hi chemistry/biology friends, does anyone have a link to resources for writing effective alt text for organic mechanisms and/or biomolecular structures? 🧪

A roadmap for equitable reuse of public microbiome data www.nature.com/articles/s41... #jcampubs

📣 I am seeking postdoctoral or faculty positions starting in 2026. My research focuses on aging, health, and machine learning, and published multiple papers in leading journals. Any opportunities would be appreciated, thank you for sharing! 😊 More about me: researchportal.helsinki.fi/en/persons/x...

Assistant Professor Plant or Fungal Genomics. Univ of Wyoming. eeik.fa.us2.oraclecloud.com/hcmUI/Candid...

Well don't I feel stupid

In reporting this piece on the new trial for a Huntington's treatment, I was struck by one thing in particular: The joy. One of my sources wept for joy. He has spent his entire career studying this disease, he said it was the happiest day. www.sciencenews.org/article/hunt...

Enhancing genome recovery across metagenomic samples using MAGmax academic.oup.com/bioinformati... #jcampubs

Omg so my lab's main focus is marine metagenomics, and someone just emailed me referring to my research as "Blue Soup and Earth's Blue Soup" and omg I love it so much. Also why the heck didn't I think of this sooner.

you mean like skylight.social ?

I know this is just one cohort but this feels like such a long time coming win (especially in the current anti-DEI climate): decades of feminism finally raised a generation of girls who see themselves as astronauts (after many who came before who broke the glass ceilings).

I laughed at first but seriously what kind of self-important jerk would write this.

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols. Thread 1/n

Ok now to update my Blue Soup presentation for tomorrow 😆 I really wanted to do a few more experiments this week to add even more onto it, but alas deadline blitz won out.

Only serial killers prefer Google Slides.

I keep trying to get people to recognize that my having a PhD says a lot more about me being stubborn than me being smart.

a new mRNA therapy apparently can cut the rate of Huntington's disease progression by ~75%. yet more miracle shit www.bbc.com/news/article...

DISNEY: "OK, we are putting Jimmy Kimmel back on the air. You can resubscribe now." ME: "I unsubscribed because you immorally bowed to fascism. I'm not going to resubscribe because you immorally bowed to finances."

Ahh! She beat me to the announcement - do join us! The inimitable @bielleogy.bsky.social is our next speaker in the @calstate.bsky.social Bioinformatics Webinar series! This Friday, noon Pacific via Zoom. Deets below.

Giving a webinar on #BlueSoup this Friday, in case anyone wants to pop in during their lunch!

Clarifying Terminology in Microbial Ecology: A Call for Precision in Scientific Communication enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... #jcampubs

Went to Costco and left only with a bag of Cece's pain meds and a Costco sized bottle of tequila. Not only did no one flinch, but the lady at the checkout said "just one?"

preprint with an awesome and fun title (and on a cool topic!): bsky.app/profile/robp...

✨Célia Souque just showcased the outcomes of the 12th Microbial Bioinformatics Hackathon at IMMEM XIV. She brilliantly presented the first sneak-peek of PORT – Plasmid Outbreak Reporting Tool! 🧬 Looking forward to continuing this collaboration with PORT! #IMMEM #Hackathon #Plasmids #ESGEM #ESGMAP

I'm really heated from a couple interactions this morning please calm me down and distract me with fun things.

Update: THEY DIDN'T EVEN REALIZE IT WAS BEEPING. (I brought them a 9V battery this evening)

I have gone zero days since January 20th without saying “Imagine if Obama had done this”.

ONT seq folks: If you only loaded libraries from 1 DNA sample (across 4 barcodes) on a MinION run, is there any reason you can't grab the unidentified/unindexed reads (or reads mistakenly called as other barcodes) to use in your analyses?

My neighbors are clearly serial killers because not only are they neglecting a low battery fire alarm, but they left the window to that room open (which faces our house).

Senegal just introduced a single shot hexavalent vaccine which covers: Tetanus, diphtheria, whooping cough, polio, hepatitis B, and Haemophilus influenzae type b www.gavi.org/vaccineswork...

Alright I have something useful for you to do. Think of any teachers and librarians you know. Do they know about Skype a scientist? Our program matches classrooms & other groups w/scientists for virtual Q&As. It’s free! They can sign up here! www.skypeascientist.com/sign-up.html #Edusky #StemED

Bye, Hulu.

I slept horribly last night, worrying about something, spent the day putting out metaphorical fires and helping people in distressing situations, and then, shockingly, I had a less than ideal performance in my lecture class today.

It's amazing how those railing against cancel culture for the past decade are now exposing themselves as the highest order of hypocrites.

What is the current preferred hybrid genome assembler for mammalian genomes? We have Illumina and ONT data. There is a draft reference genome from a different population, but no complete one.

🥰 and 🤣. We are better when we collaborate. Arun has also grown my lab's dry capacity in a major way over the years.

Any recs on primer alignment tools for large custom Euk genome seqs? (basically I have a primer set and I want to see the sequence it amplifies in this particular genome).

I bring entirely too much energy to every class I teach where I require a refractory period after each, especially lectures. #spent

This is f*cking bonkers…mRNA vaccine tech is an incredible innovation that will ultimately save many many lives. We should be finding and researching ways to make it work even better rather than cowering in fear out of ignorance of basic biology

This is the graph we show whenever someone talks about how back in the old days there weren't (people who are not whoever the person speaking thinks are the default). Mostly we do this to underscore that a rise in apparent frequency isn't always a rise in real frequency.

Fascinating: giving yeast H3K9 methylation to see what happens Chromatin landscape of budding yeast acquiring H3K9 methylation and its reader molecule HP1 www.biorxiv.org/content/10.1...

California is devising a plan to create their own National Institutes of Health to counter federal cuts to science research.

I had a dream last night that I got cancelled on here for an imaginary video that was taken out a context so that sucked.

Lolllllllllll my X account got suspended for "inauthentic behavior"??? The only thing I've done is DM my colleagues in Utah to check on them.

Interested in joining our lab (dunnlab.org) as a postdoc to work on siphonophores, processes that structure diversity in the open ocean, or natural history? If so, please reach out to discuss a nomination for the Donnelley Postdoctoral Fellowship - yibs.yale.edu/donnelley-fe...

I couldn't rest. Regrouped, went back to lab and I HAZ REGAINED MY DIGNITY.