Small update from AllTheBacteria (allthebacteria.org). Assemblies can be bulk downloaded from OSF as before, or you can now get individual assemblies from AWS. We now also have a LexicMap index on AWS, so you can align your favourite gene against 2.4million bacteria (next post for price estimates)

Celebrate International #DayofImmunology by treating yourself to one of our events or training courses! 🎉 Whether its our Diversity in Immunology event, next week’s Flow Cytometry training, or the BSI Immunology Awards - there's something for you 👀 bit.ly/3v2aAi1

👶🏼 Many #vaccines are not effective in newborns. So how do we protect them from infectious disease? 🤰🏽 By vaccination in #pregnancy! Here we review… 💉 Established campaigns vs whooping cough, flu, COVID 💡 New approaches to RSV, GBS 🌈 Future challenges, opportunities #ReproSky #ImmunoSky #IDSky

Today marks the start of #WorldImmunisationWeek! ⭐ Get inspired by reading our latest #CelebrateVaccines blog, which explores how the new RSV vaccine is cutting NHS costs and protecting vulnerable populations. 🔗 bit.ly/42V1NwZ #VaccinesWork #HumanlyPossible

Jess read the “dire wolf” preprint so you don’t have to. A long, exasperated and heroic evening thread by someone who knows what they are talking about, which shows the whole thing to be even more flakey than we thought. We salute you, @jfmclaughlin92.bsky.social!

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

Anti-citrullinated protein antibodies arise during affinity maturation of germline antibodies to carbamylated proteins in rheumatoid arthritis https://www.biorxiv.org/content/10.1101/2025.03.22.644346v1

📆 Mark your agenda for the 25th European Conference on Computational Biology! It will take place in Geneva, Switzerland, from 31 August-4 September 2026. 👉 Save the date and stay tuned for more updates as we get ready for #eccb2026

13 chair positions open @inserm.fr to lead a junior research group in France covering #neuroscience, #immunology, #bioinformatics, #bioengineering, #biotherapy, #public health pro.inserm.fr/rubriques/co... 🧪🔬

6 days left to apply to the Post-doc opening in our lab @ebi.embl.org to develop&apply #bioinformatics & #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data: embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

We are advertising for a PhD position to study bacterial metabolites in C. elegans, funded by the MRC Microbes, Microbiomes and Bioinformatics training programme @uniofeastanglia.bsky.social @biouea.bsky.social. Open to UK and international students. www.findaphd.com/phds/project...

Today I taught about phenylketonuria and eugenics. An important lesson, especially in times of nazis. Blog post: #iTeachBio #SciTeachUK cmooreanderson.wixsite.com/teachingbiol...

Great article from Ewen Callaway in @nature.com about how #SARSCoV2 has helped us better understand viruses - including the areas where we still have much to learn. “This was one of the first times where evolutionary biology became an applied science” says @jbloomlab.bsky.social

We are excited to announce a new faculty position here in Cambridge, for researchers in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Come and join us! Happy to answer questions about research, teaching and working here. www.jobs.cam.ac.uk/job/50414/

Exploring #Proteomics? Join us for a brand new and improved *Analysing Proteomics Data* #bioinformatics #training course this Wednesday 12th March, live online via Zoom 9:30-17:00 GMT/UTC www.bioinformatics.babraham.ac.uk/training.html

A mammoth circus of macabre fantasy and moral bankruptcy. I got my views on mammoths down. Enjoy. www.theguardian.com/commentisfre...

📣📣Are you looking for a postdoc? 📣📣 Does a EU or Horizon Europe assoc country (eg UK, S Korea) seem like a good destination? These fellowships a great funding option for anyone in the 🌎 👀 Check them out - next call opens 8 May 🧪 👨‍🔬👩‍🔬 marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

Join the Interdisciplinary Postdoc Fellowship Program at the European Molecular Biology Laboratory (EMBL), one of the best places to do research in modern biology and develop your career. Great opportunities for statisticians, comp. biologists, AI experts, mathem. modelers! www.embl.org/eipod-linc

Are you a postgraduate student interested in protein modelling and drug discovery? We have an exciting opportunity to join our team at GSK for a 6-9 months internship, working on an ambitious cross-department research project. Apply before March 14th! www.linkedin.com/jobs/view/41...

The IMMREP25 TCR specificity prediction challenge is now live on Kaggle! Get involved: kaggle.com/competitions... Huge thanks to: Matthew Noakes, @the-dee-em.bsky.social, @everichardson.bsky.social, @bjoernpeters.bsky.social , @adaptivebiotech.bsky.social , IEDB, @airr-community.bsky.social

PubMed has not been disappeared. It's working fine 👇🏼

NCBI websites are patchy at present, but now feel far less secure for long-term storage than they used to. For sequencing datasets consider using ArrayExpress: www.ebi.ac.uk/biostudies/a... Many, if not all, GEO datasets are on there.

here's one from us @crick.ac.uk: www.crick.ac.uk/careers-and-...

The confession of every dog owner

I am happy to discuss with any American junior researcher about transitioning from PhD>post-doc or PD>PI in Europe. I have experience in this matter! And for those who want to do a PhD, @juliusbrennecke.bsky.social listed a number of outstanding PhD programs in awesome institutes/cities.

Applications for our Future Leaders in Biomedical Sciences scholarships are now open. These scholarships are aimed at students of Black or mixed Black heritage who wish to undertake a PhD in biological or biomedical sciences. Learn more and apply. ⬇️ www.crick.ac.uk/careers-and-...

WTAF USA?

Wolfgang! @wkhuber.bsky.social Read my slow analysis manifesto and join the slow analysis movement. Let's make data analysis healthy again!

Fine, Royal Society @royalsociety.org, well said—but what about the car-selling tech fascist? 🧪 #AcademicSky royalsociety.org/news/2025/02...

New collaboration pre print out using scRNAseq meta-analysis to glean insights into role and influence of ECM during neurodevelopment and associated disorders. 👇🏼

🧠 New preprint! Our meta-analysis of scRNA-seq data (37 donors, GWs 8–26) maps ECM dynamics in human cortical development, linking many genes to NDDs. 📄 Read more:https://www.biorxiv.org/content/10.1101/2025.02.24.639826v1 #Neuroscience #scRNAseq #ECM #Neurodevelopment #Preprint #metaanalysis

These are the superpowers of the interdisciplinarian. Knowing how to communicate across disciplinary barriers is a massively under appreciated skill to have.

Donald Trump. What a nob.

Interested in an early-career fellowship (within 3 years of a PhD)? Want to work at the interface of AI with biology, health or medicine? Contact me if you want support with your application www.bmh.manchester.ac.uk/research/sup...

Do you love software engineering for exciting biological applications, open science,open source, R, Bioconductor, modern web, cloud& ML technologies? We're looking for a software engineer to work on R/Bioconductor tools for biological data science and AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Latest blogpost on Musk/Royal Society debacle: deevybee.blogspot.com/2025/02/seve... I look at the reasons that have been given for inaction, and find them wanting. @royalsociety.org

🧬 Join our lab in Toronto, Canada 🇨🇦! Exciting postdoc opening joint with @durocher1.bsky.social at the intersection of machine learning and cancer genomics-develop next-gen models to predict genetic interactions with in-the-loop validation. Apply ➡️ apply.interfolio.com/162929 or DM with questions!

Today we've hit 2,000 followers on Bluesky! 🎊 We want to thank you all for being part of our community and for your ongoing support. Let's keep the conversation going and continue advancing #immunology and #science together! ⚗ #immunosky

This 👇. Specifically, for people in the quantitative sciences, I recommend: - Have a well-tended ORCID - GitHub/GitLab repository with some of your research outputs - Personal webpage (e.g. quarto) on a static hosting service such as GitHub/GitLab Pages, Netlify, Posit Connect, ...

1. A thread about the value of doing "slow science": When I was in grad school I heard this (likely apocryphal) story about one of my favourite scientists: Barbara McClintock.

Come work at the European Molecular Biology Laboratory in the beautiful science & university city Heidelberg as a Research Software Engineer on R/Bioconductor tools for biological data science and AI ! embl.wd103.myworkdayjobs.com/EMBL/job/Hei...

If you're a non-UK scientist who wants to come to the UK for a postdoc, this year's Newton Fellowships are now open. You'll need a lab to host you (which could be me, but truly, could be any PI, so get in touch with someone you'd like to work with!) royalsociety.org/grants/newto...

This petition to stop Musk donating insane amounts of money to UK political parties just hit 70,000 signatures - up from 30k a day ago. Can we make it hit the 100k mark tomorrow and trigger a parliamentary debate?? bsky.app/profile/guys...

CSAMA 2025 Biological Data Science Summer School in Brixen, South Tyrol, 7-11 July We cover (sc)-RNA-seq and spatial omics data analysis, underlying (bio)statistical topics, multi-omics, ... All hands-on using R/Bioconductor tools. csama2025.bioconductor.eu Registration opens on 1 Feb

UK is open:) If you know someone who fits this postdoc role (nucleosomics, computational), send them our way :) generegulation.org/job-opening/

CompBio method developers: software that only runs on your computer and is not available via a repository like CRAN, PyPI, Bioconductor, is not a proper research output — just like a set of scribbled notes on your desktop is not the same as a preprint or a paper. Finish the job.

Will also add that PubMed - which indexes millions of medical articles, and makes citations and many full text articles available free of charge as a public good - is an NIH product. If it disappears, it’s not unrealistic to think that academic medicine will be massively slowed for years.

The Biostar Handbook is a comprehensive guide for bioinformatics enthusiasts, researchers, and professionals. It focuses on practical, hands-on approaches to data analysis, offering step-by-step instructions on a range of bioinformatics topics. 🧬 🖥️ #bioinformatics #genomics www.biostarhandbook.com

Is this far enough for the Royal Society? Or will this FRS need to march with a squadron of machete wielding skinheads down Pall Mall before he brings the RS into disrepute?