Congratulations to the wonderfully-talented @adrijanavarro.bsky.social on her #JBC paper out today! We took a dive into the wonderful world of glycobiology, linking it to AKT and oncogene signaling in cancer. Brought to you by Toker Lab productions. @asbmbjournals.bsky.social

congrats to you and everyone and thank you for including us in this exciting work!!

An incredible tour de force in biochemistry and cell biology by superstar @robzonculab.bsky.social lab postdoc @aakritijain.bsky.social LyLAP - a new lysosomal protease responsible for degrading integral membrane proteins in highly phagocytic cells like #PDAC cells. www.science.org/doi/10.1126/...

We stood up for science and will continue to stand up and fight, for our right, to…. do science!! @tarumur.bsky.social @dibblelab.bsky.social @piskounovalab.bsky.social @bdmanning.bsky.social

The AACR is deeply concerned that the Administration’s recent actions are threatening NIH and its mission to accelerate progress for patients with cancer and other diseases that afflict millions of Americans. Read our statement: https://buff.ly/4gRXNB8

Outstanding new study from @ralitsamadsen.bsky.social. This is a must read for everyone in the field of cancer and PI3K! Congrats to all involved!

Interesting article and viewpoints. Hopefully these new models of research and training will work, as the current model is just unsustainable.

If you are in London and are interested in the EGF receptor, come to this meeting at the Royal Society Dec 9/10 (online attendance also available). 40 years since the EGFR was sequenced (in London). royalsociety.org/science-even...

Great news for AKT inhibitors! Capivasertib in combo with abiraterone and ADT improves progression free survival in PTEN deficient prostate cancer! Anticipating approval for this combo, coming off the approval of capi in ER+be breast cancer. Good work AZ! www.onclive.com/view/capivas...

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/

PhosX is out! doi.org/10.1093/bioi... Leveraging the latest kinase specificity maps by the Cantley, Yaffe, and Turk labs and a rank sum statistic we created PhosX so now we can predict activities for nearly all kinases in your phosphodata, including the understudied ones. Check it out!

Join us in Boston! The Department of Molecular Metabolism (MET) at the Harvard T.H. Chan School of Public Health has just opened a Jr. Faculty search. Apply by January 15, 2025 at academicpositions.harvard.edu/postings/14371

Published a few weeks ago in Cancer Research, we show benefit of targeting HMCR with pitavastatin in combo with AKT inhibitors in TNBC. Many amazing people contributed, led by the magnificently talented @alissandra-hillis.bsky.social! Looking to initiate new clinical trials based on this combo. 🧪

Welcome to the Science feed! Please read our FAQs for instructions for how to be added as a contributor: bossett.io/science-feed/ Mod introductory posts linked below⬇️ Use the test tube emoji on posts you want to appear in the feed🧪 Please like the feed and make sure you follow our feed rules:

NIH research funding supported 412,000 jobs in 2023 & doubled economic returns www.fiercebiotech.com/research/rep... #NIH #research #funding

Good morning, Bluesky. Today’s #GoodMorningNews: a trial at Washington University’s school of medicine has shown great results for a vaccine that would prevent recurrence for a particularly aggressive form of breast cancer. It’s a small trial, but 3 years later 16/18 participants remain cancer free

Great to be posting science again!! Very proud of this work, thanks to a wonderful collaboration with Forest White lab at MIT, Cantley lab at DFCI, and leb by the amazingly talented @alissandra-hillis.bsky.social! Published as fully @openaccess.bsky.social in PNAS. www.pnas.org/doi/10.1073/...

I made a starter pack for people interested in signal transduction! Please include yourself or others! Tagging a few people to spread the word: @drstarbird.bsky.social @fantauzzolab.bsky.social @alextoker.bsky.social go.bsky.app/MVvjypg

Inspired by the other amazing starter packs - here's one for cancer researchers! I tried to make this broad - from immunology to genomics to cell biology and so much more.. This list also includes organizations & institutes supporting cancer researchers 🧪🔬⚕️🩺 Hope its useful! go.bsky.app/FEoaJMc

I have said goodbye to the once great platform that was Twitter, and hope to find many of my science friends and stories here on BlueSky! Is there anybody out there...?