@heykatray.bsky.social 🫶

This was a really nice review to work on: A genomic view of Earth’s biomes go.nature.com/3VTLImU by Gitta Szabó, Emiley A. Eloe-Fadrosh, Jennifer Pett-Ridge & Tanja Woyke

🎉 25 years of NRG! Feels a bit bonkers to think I’ve been at the helm for almost 12 years 🤯 Where did the time go???

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

Very happy to have contributed to this review on "non-CG" #methylation in animals now out in @natgenet.nature.com. Working again with @obog.bsky.social and Tirsa is always a pleasure. We think this not so well studied form of methylation should be more widely considered, please read: rdcu.be/eFAEk

Review: Transcriptomics in the era of long-read sequencing www.nature.com/articles/s41... (read free: rdcu.be/efBjP) 🧬🖥️🧪

There is a lack of general terminology for translated regions that does not depend on the properties of their products or their sequence. Spearheaded by Pavel (Pasha) Baranov, this primer provides a unifying nomenclature for translation units: *Translon* www.nature.com/articles/s41...

A Review in Nature Reviews Genetics discusses how genomic advances have enhanced our understanding of schizophrenia, bipolar disorder and major depressive disorder, which could address limitations in diagnostic frameworks and future treatment strategies. go.nature.com/44bKTuy 🧬 🧪

Autophagy genes in biology and disease go.nature.com/4lnHiiT #Review by Hayashi Yamamoto, Sidi Zhang & Noboru Mizushima

Methods and applications for single-cell and spatial multi-omics go.nature.com/3GkzmzZ #Review by Katy Vandereyken, Alejandro Sifrim, @bernthie.bsky.social & Thierry Voet Free to read here: rdcu.be/c6JjL

Targeted genome-modification tools and their advanced applications in crop breeding go.nature.com/3T8J8bs #Review by Boshu Li, Chao Sun, Jiayang Li & Caixia Gao Free to read here: rdcu.be/dFHti

If you enjoyed our RNA splicing collection, this @natrevdrugdiscov.nature.com Review may be of interest: Protein isoform-centric therapeutics: expanding targets and increasing specificity go.nature.com/44HDClo

Evolution of splicing model architectures go.nature.com/4eweliE Figure from our recent Review: From computational models of the splicing code to regulatory mechanisms and therapeutic implications (free to read here: rdcu.be/dVNV4)

What gif pops up when you type your name

Our August 2025 issue is now live: go.nature.com/4kIXzOI Topics include: systems biology in the single-cell era; ADAR1-mediated RNA editing; retrotransposable element reactivation and its biological impact; transcriptional condensates as temporal signal integrators; X-linked competition

Interested in using functional data to understand clinical variants? Been hunting for a good review of the topic? We just wrote one! rdcu.be/exaEU

We (with Clement Coclet, not on Bsky) had the chance to work on a broad "state of viromics" review. We tried to use this to give an overview of how the field changed over the last ~ 15 years, and also what we think are some of the major remaining challenges. Full-text access at -> rdcu.be/excHt

New review article with @mmdesai.bsky.social is out today! Grateful for the opportunity to contribute something we hope will serve the community well

More equitable methods are needed to ensure genomic research benefits everyone fairly, according to a new review article in Nature Reviews Genetics involving Genomics England researchers. Find out more: www.nature.com/articles/s41... @natrevgenet.nature.com

Happy to share my Journal Club piece in Nature Reviews Genetics, reflecting on the ancient DNA studies from Sima de los Huesos: 'A crossroads in the timeline of human evolution'. 🙂 www.nature.com/articles/s41...

Excited to share our review in Nature Reviews Genetics on cell-type deconvolution! "Cell-type deconvolution methods for spatial transcriptomics" 🔗 nature.com/articles/s41... 📖 Free access: rdcu.be/el0Ka

This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u A short thread follows 1/n

Our July 2025 issue is now live: go.nature.com/3ZzmXyQ Topics include: structural variation in the human genome; cytoplasmic mRNA decay; the mammalian segmentation clock; genetic models and genomic studies of cancer metastasis

Just in time for #RNA2025 #RNA25!

Our June issue is live and includes an editorial on RNA splicing (go.nature.com/3SdWVgk) that acts as a foreword for a new joint collection by @natrevgenet.nature.com‬ and ‪@natrevmcb.nature.com‬ on this topic (go.nature.com/3H0vEvp)

Together with the De Ridder lab www.deridderlab.nl we just published a review on deep learning as a tool for gene expression analysis/ prediction: rdcu.be/elQCc.

Also, being able to rewind is an absolute godsend! 😁 #virtual #BOG25

Playing catch-up on yesterday's #BOG25 talks virtually. Yay for meerkats! (there really should be a meerkat emoji)

Farewell sweet seaside bank holiday weekend 💙

I missed this when it came out last week... Such a multi-generational tour de force!!! www.nature.com/articles/s41...

Office day

I wrote about how we must stand and fight against the threat of eugenics. Fueled by white nationalism and scientific racism, these beliefs are factually wrong and ethically abhorrent. This fight includes supporting efforts to diversify our workforce & science. To stop now would be a deep betrayal.

Telomere-to-telomere genome sequences of six ape species: chimpanzee, bonobo, gorilla, Bornean & Sumatran orangutan, & siamang! Invaluable resource for future evolutionary studies of humans & our closest living relatives. Kateryna Makova, @aphillippy.bsky.social, Evan Eichler & co in @nature.com.🙌🧬🧪

This is high art

A study in Nature Medicine provides a cross-trait atlas of genetic and phenotypic associations across 42 female reproductive health diagnoses. https://go.nature.com/3G6slSR 🔒

Our vision for Precision Omics Initiative Sweden (PROMISE) is now published in Nature Medicine! By boosting data-driven precision omics in Sweden, we can not only empower research but also integrate it with healthcare in a new way, with an impact in 🇸🇪 and 🌎. 🧵: rdcu.be/egmXY

⭐ I'm hiring a new Chief editor for Nature Biomedical engineering, in New York, Beijing or Shanghai. Please apply here: springernature.wd3.myworkdayjobs.com/SpringerNatu...

Long reads such as @nanoporetech.com or @pacbio.bsky.social can provide insights into epigenetic. We @yileifu.bsky.social & @timp0.bsky.social )summarize the latest #Bioinformatics approaches & why this matters! Out now @natrevgenet.bsky.social at: bit.ly/4cjxUtl @bcmhouston.bsky.social @jhu.edu

Kudos to @anaconesa.bsky.social and @conesalab.bsky.social for taking on the challenge of writing not 1 but 2 reviews for @natrevgenet.bsky.social and @naturegenet.bsky.social on long-read sequencing for transcriptomics and epigenomics, respectively -- I knew it was a big ask at the time! 🤩

Review: Genome assembly in the telomere-to-telomere era www.nature.com/articles/s41... ReadCube (free) rdcu.be/dFqYo  🧬🖥️

Good morning, Bluesky. Just a warning that if you come in our mentions with anti-vax propaganda, we will hide your replies and block you. No one has time for that.

Seminar alert: How 3D genome (re)organization underlies commitment of human cells to senescence Prof. Dr. Argyris Papantonis University of Göttingen papantonislab.eu Seminar room 1 (S22-1), Haus 22 26.03.2025, 13:30 @akispapantonis.bsky.social @goetheuni.bsky.social @cpi-exstra.bsky.social RT🙏

🚀 New Paper Alert! Our latest @natrevmcb.bsky.social explores how nuclear and genome organization drive DNA double-strand break repair! 🧬 📖 Free access: rdcu.be/edViW Please 🔄 ❤️

Thou shalt not let anti-science imbeciles destroy the Department of Education so everyone can be as stupid as they are.

The stomach is an organ unique in its function, environment and exposures. How does this affect the mutations that normal cells in the stomach acquire? What does this reveal about the origins of stomach cancer? These questions and more in our @nature.com paper: www.nature.com/articles/s41...

MIT offering travel advice (or rather do not travel advice) for international visitors and green card holders. If folks at other institutions are receiving similar guidance, please consider sharing here. Please be as safe as you can.

Our April 2025 issue is now live: go.nature.com/4imQUtk Topics include: therapeutic circular RNAs; the maternal-to-zygotic transition; plant pattern recognition receptors; and insights from genetic complementation experiments into biomolecular condensate function and functional specificity

We just wanted to take a moment to thank all our new supporters! Tomorrow, there will be more of us!

Lungfish xkcd.com/3064