It’s a wrap from the 5th International Gliomatosis Cerebri Conference, held in partnership with The Rudy A Menon Foundation ❤️

We were delighted to welcome @pjferguson.bsky.social to the Glasgow Terry Fox Run for the second year in a row. Patricia gave an inspiring address about Terry’s legacy and the vital impact of the funds raised for our life-changing cancer research. Thank you for your continued support, Patricia!

For decades, we have been a driving force in accelerating progress in paediatric oncology research – leading breakthroughs that are transforming how we understand, diagnose and treat cancer in children and young people. Thread 🧵⬇️

We're proud to host the 5th International Gliomatosis Cerebri Conference in partnership with The Rudy A Menon Foundation ❤️

For Head and Neck Cancer Awareness Week, we’re showcasing the work of Dr Ben O’Leary and his team. Appointed in July 2024 to lead the Evolution and Translational Genomics Group, Dr O’Leary is focused on understanding how these cancers evolve and why they often become resistant to treatment.

#AI is set to be “an indispensable part of the toolkit” as we work to improve the diagnosis and treatment of skin cancer. Using it effectively and responsibly comes with challenges, but we’re excited to see the benefits it will bring to patients. Learn more here ⬇️ www.icr.ac.uk/research-and...

🚨 NEW cancer test could predict treatment up to a decade before it’s needed. Developed by researchers at the ICR and @idibaps.bsky.social, it reads DNA methylation to trace tumour evolution. This could revolutionise personalised cancer care across many cancer types. www.icr.ac.uk/about-us/icr...

This #GynaecologicalCancerAwarenessMonth, we’re highlighting a major milestone for women with low-grade serous ovarian cancer – a rare and historically hard-to-treat cancer. Thread ⬇️ 🧵

CaSE is excited to announce that The Institute of Cancer Research, London @icr.ac.uk has become its latest member organisation. The membership of the ICR strengthens CaSE’s advocacy for the R&D sector and widens our coalition of members. Read more⬇️⬇️ www.sciencecampaign.org.uk/press/detail...

🎉 We're proud to award the titles of Professor and Reader to six researchers from across the ICR and The Royal Marsden NHS Foundation Trust!

📢 The ICR and The Royal Marsden are partnering with #PureGym to offer free gym memberships & exercise plans to men with advanced #ProstateCancer 💪 Backed by Sir Chris Hoy, the initiative aims to break down barriers to staying active while on hormone therapy ⤵️ www.icr.ac.uk/puregym #TourDe4

NEWS 🚨 Our researchers have discovered a tiny chemical switch inside our cells that helps decide whether they keep dividing or stop for good – a finding that could influence future cancer therapies and deepen our understanding of ageing.

In the most recent episode we talked with @magnanilab.bsky.social from @icr.ac.uk about his work on epigenetic mechanisms of drug resistance and cancer cell dormancy in breast cancer. #podcast #epigenetics #chromatin Listen here: activemotif.com/podcasts-luc...

NEWS 📰 Two new studies from the ICR reveal how combining a cancer-killing virus with targeted cancer drugs can dramatically boost the immune system’s ability to fight cancer. Thread 🧵⤵️

Congratulations to Cross-Sector Experience Award recipient @christinayap.bsky.social 🎉 Through this award Prof Yap will work with AstraZeneca & Bayer to improve the design of early-phase trials, ensuring they are more effective & impactful for patients. 👉 bit.ly/45a0VWy #CrossSector @icr.ac.uk

Recruitment to cancer #ClinicalTrials is often highly selective, and some people face barriers to participation. To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️ www.icr.ac.uk/research-and...

A new drug slows tumour growth when combined with low doses of radiotherapy. Ceralasertib - a drug which blocks DNA damage repair – slowed tumour growth successfully with less than a third of the usual radiotherapy dose.

A new study has shown that whole-body MRI scans on multiple myeloma patients can detect tiny traces of cancer in the bone marrow following treatment. This gives clinicians crucial insights into a patient's response to treatment and their risk of future relapse. www.icr.ac.uk/about-us/icr...

Dr Dan Erlanson, Chief Innovation Officer at Frontier Medicines, has recommended the Chemical Probes Portal (@chemicalprobes.org) in his latest #PracticalFragments blog post, which celebrates the Portal's 10th birthday. Read it here ⤵️ practicalfragments.blogspot.com/2025/08/the-...

📣 Promising new drug combination for #OvarianCancer which led to accelerated FDA approval. Results from the Phase 1 FRAME trial, led by the Drug Development Unit across @icr.ac.uk and @royalmarsden.orga, were recently published in @natmed.nature.com Find out more 👉 bit.ly/4lW6k9A

Research from the ICR, @imperialcollegeldn.bsky.social and partner institutions including the @crukconvergence.bsky.social has made a surprising discovery that may help explain how cancer spreads – and it involves fragments so small they’ve only just been recognised.

Twenty years ago, a breakthrough at the ICR helped change how we treat cancers caused by BRCA-mutant genes – using a concept called synthetic lethality to target their underlying DNA repair weaknesses.

The Chemical Probes Portal (@chemicalprobes.org) is now 10 years old! 🎂 The free resource aims to improve the quality and robustness of biomedical experiments. We spoke with some of the team about what they've achieved so far and what the future holds. Read more ⤵️ www.icr.ac.uk/research-and...

Today is World Head and Neck Cancer Day Research from the ICR has shown that pembrolizumab, an immunotherapy drug, helps head and neck cancer patients live years longer cancer-free. Read about the results from the phase III KEYNOTE-689 trial ⬇️ www.icr.ac.uk/about-us/icr...

We were joined this afternoon by MPs @luketaylorld.bsky.social, @bobbywdean.bsky.social and @paulkohlersw19.bsky.social 👋 Luke, Bobby and Paul met with Dr @maggiecheang.bsky.social to discuss her role at the ICR and the impact of her interdisciplinary research in the @icr-ctsu.bsky.social

We're proud to be one of the supporting organisations of the Chemical Probes Portal, which was co-founded by the ICR's Professor Paul Workman. Congratulations to all involved on their 10th anniversary! 🎉 Find out more about the contributions made by the Chemical Probes Portal ⤵️

BREAKING NEWS Scientists at the @icr-ctsu.bsky.social have discovered how to predict which ER+ HER2+ cancers have a higher risk of recurrence in just 2 weeks! Breaking news - Breast Cancer Breakthrough! #breastcancer youtube.com/shorts/3rYUU...

Breast cancer test predicts relapse risk after just two weeks of treatment. The simple test, already approved for clinical use – could spare thousands of women with #BreastCancer unnecessary treatment. Read about the findings, published in @ebiomedicine.bsky.social ⤵️ www.icr.ac.uk/about-us/icr...

This week, the UK Government published its #LifeSciences Sector Plan. 💬 Our Chief Executive, Professor Kristian Helin, gave the view from the ICR 🧵⤵️

NEWS 📰: Thousands of women who undergo radiotherapy for low-risk #BreastCancer every year could be spared some of the side effects of treatment after the IMPORT LOW trial confirmed that more targeted treatments are just as effective at controlling the disease in the long term.

Schmidt Fellowships for #AI in #cancer research 2025 round is now open. These are pathway to independence fellowships between @icr.ac.uk & @imperialcollegeldn.bsky.social that support fellows to be competitive for faculty jobs at the end of the 2 year funding. www.imperial.ac.uk/jobs/search-...

BREAKING 📰 A ‘suit of armour’ protein could be targeted to stop aggressive #Melanoma from spreading. ICR scientists have discovered that SLC7A11 protects the most aggressive melanoma cancer cells from damage as they pass through stressful environments. More here ⤵️ www.icr.ac.uk/about-us/icr...

We’re proud to donate £10,425 to @icr.ac.uk to advance oncogene-driven lung cancer research, supporting the vital work of Dr Paul Huang. This is just the start — stay tuned for more big research plans. 💙🔬 oncogeneresearch.org/icr-donation #LCSM

🎉 We’re proud to share a special feature celebrating the career of Professor Steve Webb, former Head of the Joint Department of Physics at the ICR and The Royal Marsden NHS Foundation Trust. A thread (🧵⤵️)

Register now for our two-day Magnetic Resonance Guided #Radiotherapy (MRIgRT) course. 📆 22-23 September 📍ICR and The Royal Marsden NHS Foundation Trust Broaden your skills and knowledge of #MRI in radiotherapy. Early bird registration closes 15 July ⤵️ www.icr.ac.uk/study-and-ca...

A research team led by Prof. María Teresa Pisabarro (BIOTEC/ @tudresden.bsky.social) and Dr. Jörg Mansfeld (ICR) developed small molecules that block cell cycle. The molecules show promise as leads for future cancer therapies. Read more ➡️ tud.link/6c2qgu #CancerResearch #DrugDiscovery #CMCBnews

NEW 🚨 Researchers have tracked how the most common form of #OesophagealCancer and its immune environment change during treatment and adapts to survive. A thread 🧵⤵️

🧬 Today, we launch our appeal to outsmart #Melanoma and save more lives. Early diagnosis can be life-saving, but once it spreads, it becomes much harder to treat. Professor @cbakal.bsky.social's team is using AI tools to study how melanoma spreads around the body and its response to treatment.

Today, we remember Dame Deborah James on the third anniversary of her passing 🤍 We're grateful for her tireless commitment in supporting #BowelCancer research. Her Bowel Babe Fund is helping ICR's Professor Trevor Graham to understand how bowel cancer cells change as they develop around the body.

NEW 🚨 Results of the FRAME trial, which showed that avutometinib and defactinib could be used to successfully treat low-grade serous #OvarianCancer, have been published in the journal @natmed.nature.com Read the publication in full here ⤵️ www.nature.com/articles/s41...

Elen was first diagnosed with #BreastCancer in 2008. Since February, she has been treated with the drug #Capivasertib, the discovery of which was underpinned by our research. Read Elen’s full story here ⤵️ www.icr.ac.uk/research-and...

🆕research shows that an enzyme called PERK has a previously unknown role in determining the structure and behaviour of cancer cells. This finding presents new opportunities to stop the spread of many cancers, potentially benefiting millions of patients worldwide.

We're delighted to share the journey of #PI3K inhibitors: a 20-year effort from teams at the ICR, The Royal Marsden, industry partners, funders and an ICR spinout company. The results of a major trial confirmed the potential of Roche‘s PI3K inhibitor inavolisib in patients with #BreastCancer.

🧫Our #organoid facility supports @icr.ac.uk & @imperialcollegeldn.bsky.social researchers with training & expert help. Even non-lab scientists, like surgical trainee Caoimhe Walsh, are using it to explore new tools for #cancer diagnosis 🔗 bit.ly/4leguSe @hannagroupicl.bsky.social #CancerResearch

I am grateful to my mentors and the support from @icr.ac.uk @cancerresearchuk.org and @breastcancernow.bsky.social for my research ! and my team and colleagues @icr-ctsu.bsky.social

Sincere congratulations to Dr @maggiecheang.bsky.social on being awarded the prestigious CL Oakley lectureship! 👏🎉 Maggie, who is a Group Leader in @icr-ctsu.bsky.social is being recognised for her contributions to #BreastCancer research, which have helped change patient care worldwide.

Sophie Norman had just turned 16 when she was diagnosed with the #BloodCancer acute lymphoblastic leukaemia (ALL) in 2021. Now aged 19 and cancer free, she is at university and looking forward to a career in medical research. Read Sophie’s full story here ⤵️ www.icr.ac.uk/research-and...

BREAKING 🚨 Scientists from the ICR have developed a tool called EIRAS that predicts how #BowelCancer responds to treatment - helping researchers to design new personalised drugs that will keep patients living well for longer. @trevorgraham.bsky.social shares more ⬇️ www.icr.ac.uk/about-us/icr...

Incredibly humbled and honoured to have been awarded the 2025 Research Prize from @thelisterinstitute.bsky.social. ❤️ 🧬 We’re harnessing high-resolution molecular profiling + AI to uncover how cancer disables the immune system and find ways of restoring it. @icr.ac.uk #bcsm #ai #CancerResearch

Our warmest congratulations to Dr Stephen John Sammut, who has been awarded a highly prestigious research prize from @thelisterinstitute.bsky.social 🎉🏆 These awards aim to make a significant difference to the research work of scientists in the early years of running their own groups.