Last week, the FAST-Forward Boost trial completed recruitment to the Early Side Effects Substudy with 345 patients randomised. The study will now be transitioning to the main trial part of the study with a target of 4,830 patients. You can read more about the trial here: www.icr.ac.uk/ff-boost

Today is #WorldCancerDay. This week we’re highlighting impactful work from Registered CTUs. The @icr-ctsu.bsky.social IMPORT HIGH trial showed that treatment times for radiotherapy could be reduced for some early breast cancer patients. 🔗 tinyurl.com/y76mwfj8 #UKCTUNetwork #UnitedByUnique

4 February is #WorldCancerDay. This week we’re highlighting impactful work from Registered CTUs, starting with this ICR-CTSU project setting out recommendations for patient‑reported outcomes in early cancer drug trials: tinyurl.com/35p76f3u #UKCTUNetwork #UnitedByUnique @icr-ctsu.bsky.social

New research introduces the first practical guidance on how patients’ own assessments of how tolerable they find treatments (patient-reported outcomes) can be used more effectively to inform and design early-stage cancer drug trials. A thread 🧵⬇️

📢 We are doing a study called INTERACT to find out whether any groups of people have been less likely to take part in cancer studies in the UK. We'll use routine data collected by NHS England to see if there are any differences between those who joined our clinical trials and those who did not.

Delighted to share OPTIMISE-ROR – recommendations to help embed patient-reported outcomes (PROs) more meaningfully in dose-finding oncology trials. It sets out core PRO objectives to support tolerability assessment, dose selection, and PRO strategy for subsequent studies. tinyurl.com/45thervu.

Proud to have contributed to this paper, looking at real world evidence on the efficacy and safety of pembrolizumab in patients with early triple negative #BreastCancer www.sciencedirect.com/science/arti...

We are looking forward to attending UKIBCS this morning and learning about recent advances in #BreastCancer 🧪

We're looking for people with experience of cancer who would like to share their thoughts and opinions with us to help design and deliver research at the ICR. If you interested in helping research at the ICR, please fill out the registration form. forms.office.com/e/YQ0SbaJ1ix 🧪 #Research

We are currently seeking an experienced statistician/biostatistician with a strong research interest in clinical trials methodology to join our team as a Research Group Leader. You can find more details, including how to apply, here: jobs.icr.ac.uk/vacancies/12... 🧪 #ResearchJobs #Statistics

We are currently looking for a new Senior Statistician/ Principal Statistician to join our team. You can find more details, including how to apply, here: jobs.icr.ac.uk/vacancies/14... 🧪 #ResearchJobs

Are you an experienced clinical trial manager looking for a new opportunity? We are looking for a Senior Trial Manager to join our team. #ResearchJobs Find out more and apply here: jobs.icr.ac.uk/vacancies/13...

🗓️One week today! 🙌Join Prof Emma Hall & Claire Snowdon from the @icr-ctsu.bsky.social to learn how Clinical Trials Units can elevate your research, or your career! ⤵️Register below

Thanks to all our research participants and collaborators this year, and to all of you for following us. We wouldn't be able to do what we do without you all. Wishing you all a lovely festive break and a happy new year, we'll be back in 2026 to share more of our work.

We were proud to see the 5G trial - a collaboration between @icrdduiit.bsky.social and ICR-CTSU, led by Juanita Lopez - mentioned in 'Cancer Detectives: Finding the Cures'.

Yesterday our statisticians had a team meeting where they discussed some controversial topics in statistics. To celebrate Thanksgiving some of our statisticians from the USA brought in pecan pie and cornbread to share in the meeting.

Last week, principal statistician @hollytovey.bsky.social attended Reigate College to speak at their #WomenInSTEM applicants event.

Join our team! We are looking for a new Data Manager to join the team at the ICR-CTSU. You can find more details, including how to apply, here: jobs.icr.ac.uk/vacancies/13... 🧪 #ResearchJobs

We are currently looking for a new Principal Statistician to join our team. You can find more details, including how to apply, here: jobs.icr.ac.uk/vacancies/13... 🧪 #ResearchJobs

We're looking for a Senior Trial Manager to join our team. Find out more about the role and how to apply here: jobs.icr.ac.uk/vacancies/13... #ResearchJobs #ClinicalTrials 🧪

We are currently looking for a new Trial Statistician/Senior Trial Statistician to join our team. You can find more details, including how to apply, here: jobs.icr.ac.uk/vacancies/13... 🧪 #ResearchJobs

Our Sustainability Project Manager, Jessica Griffiths, attended the Conference on Research Outcomes in Environmental Sustainability jointly run by the Medical Research Council @nihr.bsky.social, and Greener NHS yesterday to present our poster on Greener Trials. #GreenSky 🧪

If you are @myesmo.bsky.social Congress this weekend, don't miss Prof @christinayap.bsky.social's presentation on Common mistakes in biostatistics: a crash course, in the Young Oncologists session tomorrow.

Our Assistant Operations Director, Dr @lisa-fox.bsky.social, is presenting the Greener Trials project at next week's @bigxresearch.bsky.social Pink October Webinar 2025. Find out more and register to attend here: bigagainstbreastcancer.org/events/big-p... #BreastCancer #GreenSky

Join our team! We are recruiting an Application Developer for our Greener Trials project. The successful applicant will develop an online Greener Trials Toolkit to help researchers assess and mitigate the environmental impact of their trials. #Greensky #ITjobs 🧪 jobs.icr.ac.uk/vacancies/13...

I’ve been speaking with yr11-13s about careers in cancer research this evening. These events always remind me of how lucky I am to work in a multidisciplinary research setting - applying statistics to things that matter to patients. @icr-ctsu.bsky.social @icr.ac.uk

Earlier this week some of our staff attended the UK CRC Trial Management Operational Meeting where they shared some recent experiences.

We were at the NIHR Biomedical Research Centre and Clinical Research Facility Research inclusion conference earlier this week, where Dr Yemi Akala presented our INTERACT Project.

Results from the TORPEdO trial were presented at the American Society of Radiation Oncology (ASTRO) Annual Meeting last week.

We are excited to be attending the 67th annual #ASTRO meeting in San Francisco where the TORPEdO primary results and the two-year toxicity outcomes from PACE-C will be presented. 🧪

Today is #WorldCancerResearchDay 🌎 👩‍🔬 👨‍🔬 We're incredibly proud to have a community that is driving innovation, making ground-breaking discoveries, and transforming the future of cancer research. Thank you to everyone who is helping us move closer to defeating cancer.

We're currently looking for a Trials Methodologist/Senior Trials Methodologist to join our team. You can find out more about the role and how to apply here: jobs.icr.ac.uk/vacancies/13... #ResearchJobs #TrialsMethodology🧪

New paper: we surveyed people in the UK who have experienced breast cancer, investigating the hidden costs and their support needs. www.nature.com/articles/s44... 🧪

Recruitment to cancer #ClinicalTrials is often highly selective, and some people face barriers to participation. To prevent these issues from limiting our progress against the disease, we're working to bridge the gap between clinical trials and real-world practice ⬇️ www.icr.ac.uk/research-and...

We're at the @abcuk.bsky.social bladder cancer training event today, to share information about our new trial COBRA.

Thank you to all the participants in FAST-Forward Boost which recruited its 100th patient last week. The trial is investigating whether #Radiotherapy to treat #BreastCancer can be given in fewer treatment visits. You can learn more about the trial here: www.icr.ac.uk/ff-boost

Congratulations to @christinayap.bsky.social for being awarded a Cross-Sector Experience Award from @acmedsci.bsky.social to support her work on early phase and adaptive trials methodology, and the integration of patient-reported outcomes.

We are looking for a new Principal Statistician to join our team. If you're interested in this role or know someone who might be, please see the link below for more details. #ResearchJobs #Statistician 🧪 jobs.icr.ac.uk/vacancies/12...

We are looking for a new Trial Manager to join our team. If you're interested in this role or know someone who might be, please see the link below for more details. #ResearchJobs 🧪 jobs.icr.ac.uk/vacancies/12...

We were joined this afternoon by MPs @luketaylorld.bsky.social, @bobbywdean.bsky.social and @paulkohlersw19.bsky.social 👋 Luke, Bobby and Paul met with Dr @maggiecheang.bsky.social to discuss her role at the ICR and the impact of her interdisciplinary research in the @icr-ctsu.bsky.social

On Friday, PhD student Emily Alger @mle-alger.bsky.social will present her work “International consensus-driven recommendations for patient-reported outcome research objectives in early phase dose-finding oncology clinical trials: OPTIMISE-ROR” at the ESMO TAT Asia Congress. 🧪

We are looking for a new Data Manager to join our team. If you're interested in this role or know someone who might be, please see the link below for more details. #ResearchJobs 🧪 jobs.icr.ac.uk/vacancies/12...

We've just published a paper describing our work with patient and public advisors on our SPRUCE study. @morgainestiles.bsky.social researchinvolvement.biomedcentral.com/articles/10....

Published today in @natmed.nature.com www.nature.com/articles/s41... combination of avutometinib and defactinib in LGSOC. @icr.ac.uk‬ @icrdduiit.bsky.social‬ @icr-ctsu.bsky.social @royalmarsden.org @ecmc-uk.bsky.social @nihr.bsky.social‬ ‪@crukconvergence.bsky.social @cancerresearchuk.org ‪

Results of the PERSEUS1 trial were published in European Urology Oncology this week: www.sciencedirect.com/science/arti...

PACE-C 12-week acute toxicity results were published online in @thelancetoncol.bsky.social last week. 🧪 You can read the paper here: www.sciencedirect.com/science/arti...

I am grateful to my mentors and the support from @icr.ac.uk @cancerresearchuk.org and @breastcancernow.bsky.social for my research ! and my team and colleagues @icr-ctsu.bsky.social

Our statistician, Monisha Dewan, will be giving a rapid fire talk and presenting a poster on ‘Predicting risk of recurrence using a multiparametric algorithm for women ≥70 years old with early ER+HER2- tumours in the POETIC trial’ at the @nihr.bsky.social statistics conference tomorrow. 🧪

The primary results of the HERMES #ClinicalTrial have been published in the Red Journal. HERMES investigated whether patients with localised #ProstateCancer are best treated with 2 fractions of #SBRT over 8 days or 5 fractions over 10 days. www.sciencedirect.com/science/arti...

Congratulations to PhD student, Emily Alger @mle-alger.bsky.social, who received the American Statistical Association Biopharmaceutical Scholarship Award in May, recognizing her notable achievements, research, leadership, volunteering and project work in the area of biopharmaceutical statistics. 🧪