In the October issue of #GENETICS, @michaelphart1.bsky.social and colleagues report #Celegans mutant analysis that identified conserved #autism genes with functions in experience-dependent neuron remodeling and circuit plasticity. buff.ly/ZrxH4rM

The latest #G3journal study attempts to distinguish between different possible expectations for transcriptomes associated with phenotypic nonspecificity, a phenomenon where transcription factor phenotypes are rescued by other transcription factors. buff.ly/QzrVo2u

In the October issue of #GENETICS, @bahome.bsky.social and the team investigated unexplained phenotype differences among premature termination codon variants caused by small, frame-shifting deletions in Zfp423 in mice. buff.ly/SWA7csm

The latest #G3journal report characterizes the lysosome-related organelles, aka gut granules, in different #nematodes, showing how blue light stimulation of these autofluorescent organelles generates sharp increases in fluorescence intensity. buff.ly/Gh1ndVN

🎉 New in #GENETICS: Functional Genomics & Systems Biology section! Highlighting cutting-edge studies on molecular networks, systems-level insights, and innovative methods. Read more: buff.ly/wWVZdrS%F0%9...

The latest mutant screen report in #G3journal showcases albino mutant strains of Exophiala dermatitidis—a polyextremotolerant black #yeast species—with cell morphology and growth pattern changes. buff.ly/xmhlNa3

📢 NEW GENOME ALERT Magnusiomyces clavatus is a fungal pathogen that causes severe systemic infections in immunocompromised patients. Learn more in #G3journal about the pathogen's newly annotated genome and the diagnostic value it brings to the clinic. buff.ly/q7sFePJ

New in #GENETICS: Villwock et al. demonstrate that widespread pleiotropy rather than genetic linkage drives the negative genetic correlation between total carotenoid and dry matter in cassava. buff.ly/K2DFtMm

New study in #G3journal presents a novel Bayesian divergence-based framework for multitrait ordinal selection, along with a Multitrait Parental Selection #Rstats package that enhances selection efficiency in breeding programs. buff.ly/3BSrb0R

⏳ Don’t forget! Nominations are open for the Hugo Bellen and Catherine Tasnier Drosophila Neurogenetics Lecture. $5,000 + a lecture at #Dros26 for an early career scientist or faculty in #Drosophila neurogenetics. Deadline: Nov 6 👉 buff.ly/QAFMr7a

Latest in #GENETICS: Chang et al. uncover a physiological role of mitochondrial sirtuins, sir-2.2 and sir-2.3, in #Celegans lifespan regulation, showing that sir-2.2 and sir-2.3 use overlapping but distinct mechanisms for regulating lifespan. buff.ly/xITAFSP

Latest work from @shapirorebecca.bsky.social and colleagues in #GENETICS shows how allele-specific CRISPR single guide RNAs can efficiently induce loss of heterozygosity events in fungal pathogen Candida albicans. buff.ly/lMThaTO

In #G3journal, Huimei Yang and Yan Wang showcase a new genomic resource for Zancudomyces culisetae generated using multiple sequencing platforms—a symbiotic fungus inhabiting the digestive tracts of insect larva—to advance insect gut fungal research. buff.ly/BFYMsJW

📢 NEW GENOME ALERT A new sequence assembly and annotation of the ball python published in #G3journal will provide a valuable resource for studying snake-specific traits and evolutionary biology.

New tech brings big opportunities—and big challenges. A new collection of #G3Journals + #GENETICS papers tackle biases, computational hurdles, and more.🔍 Read the papers: buff.ly/1cm0BcE 📝 Have work that fits? Submit your paper to G3!

🚨 TODAY: Apply to serve as a graduate student or postdoc representative on the GSA Board of Directors! 📅 Deadline: October 17 🔗 buff.ly/e7eaq6b GSA’s future relies on voices like yours!

In #GENETICS, Whited et al. identify a genetic pathway involving cadherin CDH-3, YAP-1/YAP, and EGL-44/TEAD, describing a cell-cell adhesion-driven signaling pathway that ensures compartment-specific cell clearance in #Celegans. buff.ly/xFcO1pe

Abstract submission and registration for #Fungal26 is now open! 🧬 Browse abstract submission topics online and start preparing your abstract today. Learn more: buff.ly/UxUroSj

🚨 LAST CHANCE: Apply to serve on a GSA committee by tomorrow, Oct 17! Help shape the future of genetics: 🟰 Equity & Inclusion: buff.ly/Xqly96y 💰 Microgrant Review: buff.ly/dfXGrvj 🏅 Awards Promotion: buff.ly/uIc73QG 🏫 Education: buff.ly/WQQmxsc

New study in #GENETICS from @anaignatieva.bsky.social and @linoafferreira.bsky.social shows how ancestral recombination graphs can help detect "phantom" genetic interaction signals that arise due to genealogy and not because of epistasis. buff.ly/TQARoDp

In #GENETICS, @yadirapga.bsky.social, @3rdreviewer.bsky.social, and colleagues probed germline mutation rate in the gray short-tailed opossum, discovering that the majority of mutations are inherited from the male parent. buff.ly/qiaRzoK

A new study in #GENETICS identifies how a single amino acid substitution in #Celegans ribosomal protein RPL-36A confers complete resistance to cycloheximide, a known inhibitor of the elongation stage during protein translation. buff.ly/mU7j8H0

In #GENETICS, Simon H Martin describes a simple model-free approach for genealogical inference called Sequential Tree Inference by Collecting Compatible Sites and confirms that this framework is accurate for ancestral recombination graphs inference. buff.ly/EiuKHfo

Debating submitting an abstract to #Dros26? 🪰 Organizer Pelin Volkan showcases the benefits of presenting your science at a conference like Dros, for scientists of all career stages—pivotal to your professional growth and career advancement. Read more in Genes to Genomes: buff.ly/rdwHamI

How do spatial population structures affect sweep dynamics and signatures? Check out this #GENETICS study that uses simulations to pinpoint the need for better accounting for spatial population structure when making inferences about selective sweeps. buff.ly/uEQ3bmZ

In #GENETICS, Das et al. show that E2F activity is crucial for the exocrine function of #Drosophila salivary gland, where the loss of E2F activity leads to increased DNA damage and the accumulation of cytoplasmic DNA. buff.ly/T9eMkjv

Latest in #GENETICS: Check out a new #rstats package, Codon Usage Bias Analysis (cubar), that can calculate common codon usage indexes in a fast, efficient, and user-friendly manner. buff.ly/7cQcNFn

In #GENETICS, Tetsuya Akita presents a new theoretical justification for using the effective number of breeders as a life-history-independent metric to quantify demographic stochasticity and connect genetic monitoring with population viability analysis. buff.ly/Qvef2So

Former ECLP Multimedia Subcommittee co-chair Jiae Lee shares her experience becoming an advisor after being an ECLP member herself. The role allowed her to stay connected with former members & projects, and more importantly, it let her inspire the next generation. Apply now: buff.ly/u3MuK9O

New in #GENETICS: A targeted #Drosophila RNAi screen of conserved chromatin regulators identified new genetic modifiers that intersect with Polycomb, affecting transcriptional balance and developmental homeostasis. buff.ly/0SgEfyy

@johriparul.bsky.social and colleagues use a diffusion theory to model selective sweeps in a non-recombining population and provide expressions for site frequency spectrum at linked neutral sites. Read more in #GENETICS about the importance of this statistical approach: buff.ly/EiN8PtQ

New in #GENETICS: Using deep mutational scanning to create a mutant library and measuring protein–protein interactions, @christianlandry.bsky.social and the team determined the in vivo binding strength of motifs that bind to the SH3 domain in #yeast mutants. buff.ly/uOXTpZG

The #Yeast26 website is live—start planning your conference attendance now! 🧬 Browse abstract submission topics, key dates, speaker & venue info, details on travel funding, and more: buff.ly/HFIt31b Bookmark the page to stay updated as new information becomes available!

🌍 Want to fund your research abroad? Join GSA’s Grants and Funding in Europe panel to hear how to secure international support for your work. 📅 Oct 20 | 11 a.m. EDT 🔗 buff.ly/qvdEkMu @limor-zwi-dantsis.bsky.social

In #GENETICS, @jsrinivasanwpi.bsky.social and the team present a rescue-by-feeding approach, showing that feeding engineered E. coli containing neuropeptides to #Celegans mutants can successfully rescue behavior defects in worms. buff.ly/Qdw9Nsq

New work in #GENETICS from @bahome.bsky.social and the team investigates unexplained phenotype differences among premature termination codon variants caused by small, frame-shifting deletions in Zfp423 in mice. buff.ly/8xVpAkC

New research in #GENETICS from Yongtao Guan and Daniel Levy presents a novel knockoff construction method, which demonstrates superior performance in identifying #proteomic signatures of age and genetic fine mapping. buff.ly/WiV40uA

A new #GENETICS study shows that the SAGA complex-mediated H3K9 and H4 acetylation is sufficient and essential for induction of filamentation in the human fungal pathogen Candida albicans. buff.ly/MTiVpgT

In #GENETICS, Christ et al. present a general framework for using inferred local ancestries to boost standard single-marker testing association signals in the presence of allelic heterogeneity. buff.ly/3HNc64G

⏰ Reminder: Apply by October 17 to serve as a graduate student or postdoc representative on the GSA Board of Directors. Lend a voice to your early career community! 🔗 buff.ly/e7eaq6b

What is the likelihood of evolutionary rescue on a mutator background that either emerges de novo or pre-exists in the population before a severe environmental change? Learn more in #GENETICS as Marwa Tuffaha and Lindi Wahl address this question: buff.ly/vKUP7fe

In #GENETICS, @tiboleroyinen.bsky.social et al. present the largest #GWAS catalog for roses to date and show how genetic makeup changed from a historical European to a near-Asian genetic background within a few generations during rose breeding in Europe. buff.ly/tw4vVUl

New in #GENETICS: Using Chip-seq and mutant analysis, Fernandez et al. show the transcriptional control of the male tail tip morphogenesis during development by the master regulator of a male-specific morphogenesis gene DMD-3. buff.ly/EGahYv2

In #GENETICS, @michaelphart1.bsky.social and colleagues performed a mutant screen in #Celegans to identify conserved #autism genes with functions in experience-dependent neuron remodeling and circuit plasticity. buff.ly/f5UYogl

✈️ Hey undergrads! Take your research on the road with a GSA Undergraduate Travel Award. Get funding to present at a GSA Conference, connect with scientists, and share your science. Apply today: buff.ly/T4XFp4A You can use this to attend #Dros26, #Fungal26, #PEQG26, or #Yeast26 next year!

⏰ Reminder: There’s still time to apply to serve on a GSA committee! Help shape the future of genetics: 🟰 Equity & Inclusion: buff.ly/T6mr2FM 💰 Microgrant Review: buff.ly/SXwgdYo 🏅 Awards Promotion: buff.ly/iROQeg9 🏫 Education: buff.ly/pJAXz1z

Science is intertwined with eugenics, and eugenic ideologies continue to negatively impact #Indigenous communities and science today. Read a timely and important perspective piece in #GENETICS from @jazlynmooney.bsky.social and colleagues: buff.ly/T7rbV3k

The October #G3journal cover features Deroceras laeve—a widely distributed land slug suitable for research to comprehend the mechanisms underlying regeneration largely unknown in mollusks. Read the issue: buff.ly/PNSEEvz 📸: Alfredo Varela-Echavarría 1/2🧵

The October #GENETICS cover shows phenotypic variation in rose flowers across different periods of 19th-century breeding history, illustrated with some of the rose varieties preserved in the ancient rose garden Roseraie Loubert.🌹 Read the full issue: buff.ly/BYzknt9 📸: @tiboleroyinen.bsky.social

A 🆕 episode of Genetics in Your World is now available! ECS Multimedia Subcommittee co-chair @ecoevogal.bsky.social interviewed Dr. Shraddha Lall of Harvard University on her research covering selection for phenotypic variability in Drosophila. Listen now: buff.ly/M9uafT5 🎙️