INCREDIBLE CURVES

We've seen some remarkable outcomes in people with advanced, refractory cancers, including pancreatic, melanoma, and renal, with personalized neoantigen mRNA vaccines. But this work is now endangered. www.scientificamerican.com/article/pers...

He had a whatnow?

Ottawa! Next week! 👇 This is a critical time. A knowledge crisis. How did we get here & what can we do? How to Escape the Fake: Making Good Policy in the Age of Misinformation : irpp.org/irpp-event/f... via @irpp.org @cmadocs.bsky.social Hope to see there!

How's the OB-GYN presence here #MedSky? Been thinking about about the tynelol/autism fiasco and interested in seeing how colleagues in those fields are doing

Love it when the newspaper publishes a photo of me with the caption, "Embarrassing and sad."

I don't understand It's a natural supplement with a natural yellow dye. What do you mean it can - *checks notes* Cause convulsions, diarrhea, and coma? www.cspi.org/cspi-news/fd... #MedSky #RxSky

Fewer toddlers developed peanut allergies after guidelines recommended introducing peanut products in infancy, a large primary care registry study showed. 🥜⬇️

Happy to see the tradition of "robbing the Louvre in the most basic way possible" return.

*Looking over at the US* "Damn that's fucked up" *Get email from Ontario grad student union* "Hey wait a minute"

One of the insidious problems with medical disinformation is that it "hogs the air". We spend time debunking BS and assuaging fears that we could have spent having actually valuable discussions. #MedSky #RxSky

There's another lesson in polio too. Humor me a bit: ❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis? A) 5% B) 12% C) 0.5% D) 3%

*Tiny soapbox* Calling it "Western Medicine" whitewashes historical and ongoing contributions made to modern medicine by the global community. It's meaningless and unnecessarily divisive. #RxSky #MedSky

In case there's interest: Here's a study on turmeric for OA that's got ok methodology (small though). I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper. #Medsky www.acpjournals.org/doi/10.7326/...

Here's a fun little fact about this story... #RxSky #MedSky www.independent.co.uk/news/world/a...

Confessions of a former naturopath.

My version of "don't make me tap the sign"

"That suppository made me bleed out the butt" "Oh that's terrible I'm sorry. Just to confirm: You took off the foil wrapping before inserting it, right?" "..."

New from The Strain Team: 🎊 Springer Nature Discovers MDPI 🎊 Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗). Gross! 😀 1/n #ResearchIntegrity #SciPub #AcademicSky

The ideal cutoff for adequate time-to-antibiotic delivery in septic shock is being discussed again 🤦‍♂️ Should we be required to give antibiotics in 1 hr? 3 hr? 15 minutes? 3.14159 minutes? This is worth a short thread on the background of this topic Buckle up, it's a mess... #EMIMCC #IDsky #1/6

My favorite farsi insult: Namak-nashnaz Approximate translation: Ungrateful, unappreciative. Literal translation: One who does not recognize salt 🧂 Devastating in the culinary scene, I'm sure. You're welcome.

"These things are the ideal way to help people quit smoking!" ⬇️ "Ok there are apparently more kids who use vapes than would have every smoked cigarettes" ⬇️ "Researchers are looking at using smoking cessation drugs to help kids quit vaping" jamanetwork.com/journals/jam... Medsky / RxSky

Following attacks on humanitarians in Gaza and Sudan, including on Doctors Without Borders staff, the silence is deafening. No outrage. No accountability. @chrislockyear.msf.org, our Secretary General, speaks of the cost for killing humanitarians. www.doctorswithoutborders.ca/what-is-the-...

Not to be mean but I can't even humour the usual "Why don't you move to the states? You'd make so much more money there!" conversations anymore.

If I can teach one thing to regular folks: Treat supplements with the same caution you treat prescription drugs. RxSky MedSky newzsquare.com/rates-of-liv...

Medsky / RxSky when folks are complaining about the "horrible gardening advice" going around on TikTok.

2 At first glance, section 3 might look like a really good thing. A lot of these are pillars of the science reform movement. But we've already seen these principles used for the purpose of agnogenesis—creating doubt around scientific findings to stave off regulation or push a political agenda.

I missed World hypertension day - which conveniently is in the middle of stroke awareness month. Here to remind you high blood pressure is the leading and most controllable risk factor for stroke. And for a given level of high blood pressure, the risk of stroke may be higher in women.

The reviews are in, but can we trust them? [SPOILER: NO!] Why you should be skeptical of online reviews www.ctvnews.ca/edmonton/ctv... Fun chat on CTV Edmonton about fake & manipulated online reviews. Sum: It's a problem!

On Friday, my son stayed home from school because he had a sore throat and wasn’t feeling well. He went with my husband to his office for the morning while I handled our daughter. When he came back at lunch, he was not interested in eating, saying his throat hurt too much. 1/n

Drug memes. #MedSky #RxSky

A meta-analysis of 💩 is just more powerful 💩

The SNAP trial may finally resolve some of the longest-running debates in SAB management (cefazolin vs semi-synthetic PCN? Is PCN really active vs PSSA?). Huge congrats to Drs. Joshua Davis, Steven Tong, & the global team who made this ambitious trial happen. #IDSky blogs.jwatch.org/hiv-id-obser...

On March 28 and 29, settlers and Israeli forces stormed and attacked the Jinba community in #MasaferYatta, #WestBank, #Palestine. Five Palestinians were hospitalized —two in intensive care, including a child.

Unless someone's got multiple clinical trials to cite, I stand by this rule

Interesting to see so much news about measles outbreaks and hospitalization that doesn't even mention its effect on the immune system. It's not good guys #MedSky #PharmSky www.bbc.com/future/artic...

Really great 🧵 by someone I'm excited to see on BlueSky

Alright hear me out: Laugh tracks in Academic Presentations. Cued by presenter in case their jokes don't land. Great idea or amazing idea? #Medsky #RxSky

"Severe osteopenia" is weird, right? Like it's not a helpful descriptor, especially in asymptomatic adults? Are we also telling people they have severe subclinical hypothyroidism? Am I being silly #Medsky?

Saw a patient with chronic urinary retention and nurses told me the bladder U/S showed >2L before they put in the foley. Q's for #MedSky: WTF is that actually possible? No ascites or anything

DAPA-TAVI: The #SGLT2 inhibitor dapagliflozin was superior to standard care alone in decreasing rates of all-cause mortality or worsening #HeartFailure in older adults w/ #vhdAS undergoing TAVI, resulting in a 28% relative risk ↘️. #ACC25 More: bit.ly/4cfLNsy #cvSurg #CardioSky #MedSky

Well this is an interesting (horrifying?) update to the Letby Case www.reddit.com/r/medicine/c... #MedSky #RxSky

Gavi has helped vaccinate over 1.1 billion children, saving 17 million lives. Every $1 the U.S. invests returns $54 in health & economic gains. These vaccines stop outbreaks before they reach our shores. Without them, Kansas is just as vulnerable as Kinshasa. www.reuters.com/business/hea...

Is there a level beyond "Unqualified"? Antiqualified?

I've been screaming it for years: the right in Canada is headed down an American-style path on almost every issue because the right-wing media plays that tune, and the right-wing pretend media plays that tune. It's headed in one direction, and we have never had a clearer view of where that leads.

Nothing will get you worked up about alt-med BS quite as fast as working in an oncology or med oncology unit. #Medsky #RxSky

This is your periodic reminder that pharmaceutical companies can modify and patent damn near anything. If there was a cure for ___, no one's going to leave money on the table. #Medsky #RxSky

Hospital Pharmacists #PharmSky #MedSky

Learning things the hard way can have awful long term implications. True for patient care and public advocacy.