Peter Mace
@petermace.bsky.social
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📥 208
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Protein biochemistry, kinase and ubiquitin signalling, bikes and dogs
reposted by
Peter Mace
Otago Biochemistry
3 days ago
Just confirming what we already knew: Otago Biochemist Associate Professor Lynette Brownfield is an awesome postgrad supervisor! This week awarded the Division of Health Sciences Supervisor of the year. Here she is with her group of young scientists enjoying a well-earned break amongst the rhodies.
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Peter Mace
Guillaume Thibault
5 days ago
Ready for a transformative research journey? 🚀 Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships. Hear from our students and faculty in the video below 👇
youtu.be/JeZHiXu3fgE
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NTU College of Science PhD opportunities
YouTube video by College of Science NTU
https://youtu.be/JeZHiXu3fgE
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Is the alphafold database performing really poorly, and Uniprot alphafold links broken for everyone, or just me? I've tried clearing my cache, but any tips
@ebi.embl.org
?
23 days ago
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Peter Mace
Brett Collins
29 days ago
Open Group Leader Positions at the IMB, UQ. Interested in joining us in sunny Queensland?
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Group Leader - Institute for Molecular Bioscience (IMB)
Institute for Molecular Bioscience Join a university ranked in the world’s top 50 Australia’s #1 research institute Based at St Lucia Campus About UQ What started as Queensland's first university in 1...
https://uq.wd3.myworkdayjobs.com/en-GB/uqcareers/job/St-Lucia-Campus/Group-Leader---Institute-for-Molecular-Bioscience--IMB-_R-55777
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Excellent course content for my scientific writing class!
add a skeleton here at some point
about 1 month ago
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Peter Mace
Edward T Eng
about 1 month ago
Muyuan Chen has turned structural biology into an immersive experience with his new video game Meowtabolism, now available on Steam. Try the demo here:
store.steampowered.com/app/4045010/...
Give Muyuan feedback:
steamcommunity.com/app/4045010
#ScienceGaming
#StructuralBiology
#CryoEM
#STEMOutreach
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Peter Mace
Josh Hardy
about 1 month ago
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates
#RFdiffusion
,
#ProteinMPNN
,
#FAMPNN
,
#AlphaFold2
and
#Boltz-2
. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028
#proteindesign
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We're hiring! Come join us as a Lecture/Senior Lecturer in the fantastic supportive Biochemistry Department at the University of Otago. Dunedin is a super-liveable city, which just happens to have some of the best access to nature (and biking) in Aotearoa......
otago.taleo.net/careersectio...
about 2 months ago
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Peter Mace
Ben Williamson
2 months ago
Peer reviewers are exhausted. It's common to spend *months* inviting reviewers, getting refusals, inviting more, maybe 12 or more, then 2 agree but 1 doesn't complete, so you go again. That's why your paper is in limbo. I'm very sorry, it's awful, but it's also an untenable academic labour issue.
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Peter Mace
Pierre Polyester
2 months ago
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Peter Mace
Mikhail Spivakov
4 months ago
Translational research is digging for gold. Basic research is learning where and what to dig. The more funding is diverted to translation, the more we deplete the research ecosystem, driving the supplies of "gold" - immediately translatable findings and innovations - to unsustainably low levels.
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Peter Mace
Otago Biochemistry
3 months ago
Biochemistry Special Seminar Wed 27 Aug 1pm Rm BIG13 Distinguished Professor Natarajan Kannan, University of Georgia Evolution of regulation in signaling systems: From ancient cores to modern complexity
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Vinnie Tagliabracci kicking off the final morning of
#iubmbkinases
, post conference dinner crowd still strong (with coffee....)
3 months ago
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Peter Mace
James Murphy
3 months ago
Onward into metabolism. Kicking off the pm session with Grace Gong (LMB) and John Burke (UVic)
#iubmbKinases
@iubmb.bsky.social
We thank
@biochemsoc.bsky.social
#BiochemJ
for their support of this session. The weather couldn’t even lure us away!
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Welcoming Grace Gong back to NZ to kick off afternoon number 3, lipid kinases at
#iubmbkinases
3 months ago
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Peter Mace
James Murphy
3 months ago
Day 3 of
#iubmbKinases
@iubmb.bsky.social
and many of us sprung up to take this photo through the conference room window - even during talks. Queenstown turning on a stunner of a day, matched only by some terrific science
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Peter Mace
James Murphy
3 months ago
Flying start to the
#iubmbkinases
meeting in beautiful Queenstown, NZ. Jubilee Award from IUBMB to Kevan Shokat yesterday, and a kinase masterclass from Susan Taylor this morning
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Peter Mace
Troy Baisden
3 months ago
Robust debate in Parliament yesterday, with questions from Scott Willis to Shane Reti MP about cuts, job losses and whether reprioritisation will yield clarity or any benefits. The answers aren't reassuring but it is good to see this getting attention.
youtu.be/Vam6UmnvtyY
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RSIT in Parliament – Oral Q5 14 Aug 2025
YouTube video by New Zealand Association of Scientists
https://youtu.be/Vam6UmnvtyY
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Peter Mace
Tigist Tamir
3 months ago
This!
journals.biologists.com/jcs/article/...
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Why would anyone want to be a scientist?
It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently...
https://journals.biologists.com/jcs/article/138/15/jcs264284/368759/Why-would-anyone-want-to-be-a-scientist
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Four weeks left for abstract submission and early-bird registration for the NZ Society for Biochemistry and Molecular Biology annual meeting!! Adele Williamson and William Kelton are putting together an amazing program including outstanding plenary speakers!
www.nzsbmb.org/conference-2025-rotorua
3 months ago
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Excited to see this work led by Cameron Reddington and Annabel Walsh out in
@febsj.bsky.social
— ASXL proteins share a PHD domain that is not a PHD domain, evolved to bind an MBD domain that is not an MBD domain!
febs.onlinelibrary.wiley.com/doi/10.1111/...
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FEBS Press
A plant homeodomain (PHD) at the C terminus of additional sex combs-like (ASXL) proteins is recurrently truncated in disease. In the current study, the ASXL PHD was shown not to bind histone modifica...
https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.70206
3 months ago
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Peter Mace
Amro Hussien
4 months ago
For every €1 invested in Horizon Europe programme, Europe is expected to get as much as €11 in GDP return Source:
www.innovationnewsnetwork.com/horizon-euro...
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Horizon Europe delivers €11 GDP return for every €1 invested
Learn how Horizon Europe is driving innovation and growth across the EU, with up to €11 in GDP returns and sixfold societal benefits by 2045.
https://www.innovationnewsnetwork.com/horizon-europe-delivers-e11-gdp-return-for-every-e1-invested/57616/
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A fantastic oral program is now in place, but you can still register and submit an abstract for the IUBMB Focussed Meeting on (Pseudo)kinases in signal transduction! Outstanding setting, with ample chances to exchange ideas with the top kinase minds in the world!
www.ivvy.com.au/event/IUBMB25/
4 months ago
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It's June 20 in New Zealand, which means it's the last day to have your abstract considered for oral presentations at the IUBMB Focussed Meeting on kinases and pseudokinases!
add a skeleton here at some point
5 months ago
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Check out the view today from the venue—scoping for the IUBMB Focussed meeting on (pseudo)kinases! Abstracts and early bird registrations closes this week!
www.ivvy.com.au/event/IUBMB25/
@pseudokinase.bsky.social
@iubmb.bsky.social
5 months ago
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Peter Mace
Ben Eltham
5 months ago
Excellent article by Rock Morton in the Saturday Paper this morning, on consultants Nous. These guys are so endemic in university managements I ended up writing a whole paper about them. They're basically vampires
www.thesaturdaypaper.com.au/news/educati...
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‘Mind-boggling stupidity’: The consultancy that captured universities
Nous Group has slowly taken over the university sector, filling VCs’ offices with ex-staff and buying ‘incredibly sensitive’ data that is sold back for benchmarking.
https://www.thesaturdaypaper.com.au/news/education/2025/06/14/mind-boggling-stupidity-the-consultancy-that-captured-universities
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Only one week left to submit your abstract and register at early bird rates for the IUBMB Focussed Meeting - (pseudo)kinases in signal transduction. Sign up and register by June 20!! Join
@pseudokinase.bsky.social
Natalia Jura, and a who's who of kinase research!
www.ivvy.com.au/event/IUBMB25/
5 months ago
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Peter Mace
Laura Edgington-Mitchell
6 months ago
The 13th General Meeting of the International Proteolysis Society will be held in Búsios, Brazil Oct 26-30, 2025. Training workshops will be held at the Instituto Oswaldo Cruz Oct 23-23. Register now! Links below. 1/3
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With less than a month to submit abstracts for the
@iubmb.bsky.social
Focussed Meeting on (pseudo)Kinases in stunning Queenstown, we are delighted to announce travel scholarships for selected ECRs thanks to
@biologists.bsky.social
and the Maurice and Phyllis Trust!
www.ivvy.com.au/event/IUBMB25/
6 months ago
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Peter Mace
Gregory Kohn
6 months ago
In an age of triumphant managerialism, we must remember that giving researchers support, autonomy, and freedom results in miraculous things. Another point is that the government required AT&T to invest in basic research to avoid being treated as a monopoly.
1517.substack.com/p/why-bell-l...
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Why Bell Labs Worked.
Or, how MBA culture killed Bell Labs
https://1517.substack.com/p/why-bell-labs-worked
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Peter Mace
University of Otago - Ōtākou Whakaihu Waka
6 months ago
Two Otago academics, Dr Olivia Harrison and Professor Jemma Geoghegan, have been awarded Prime Minister's Science Prizes for their outstanding work on managing viruses and managing anxiety. Ngā mihi nui! 👏 Read more here:
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Prime Minister’s prizes awarded to two Otago academics
Work on managing anxiety and managing viruses has resulted in two Otago academics receiving Prime Minister’s Science Prizes.
https://www.otago.ac.nz/news/newsroom/prime-ministers-prizes-awarded-to-two-otago-academics
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reposted by
Peter Mace
6 months ago
Congratulations to Professor Kevan Shokat from the University of California, San Francisco, 🇺🇸, recipient of the IUBMB Jubilee Award Lecture. His award lecture will be presented at the IUBMB Focused meeting on "The Emerging roles of (pseudo)kinases in signal transduction".
@asbmb.bsky.social
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Peter Mace
World Bollard Association™️
7 months ago
For the first time in history, we can proudly show you a DOUBLE German bollarding. This has NEVER been seen before so congratulations to us.
#WorldBollardAssociation
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reposted by
Peter Mace
7 months ago
📢Searching for REVIEWS EDITORS for IUBMB Life, BioFactors, and Biotechnology and Applied Biochemistry. ‼️Apply by May 31, 2025
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Peter Mace
7 months ago
📢Searching for IUBMB Publications Committee members ‼️Apply by May 31, 2025
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Peter Mace
Nature Biotechnology
7 months ago
By combining high-throughput protein engineering with machine learning, bespoke SpCas9 enzymes are identified that outperform evolution-based and engineered nucleases and base editors in human cells.
www.nature.com/articles/s41...
#NBTHighlight
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Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning - Nature
Nature - Custom CRISPR—Cas9 PAM variants via scalable engineering and machine learning
https://www.nature.com/articles/s41586-025-09021-y
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Peter Mace
IECB Bordeaux
7 months ago
We are recruiting 🤩🤩🤩!!! If you are looking to establish ylur lab in a multidisciplinary institute with state-of-the-art facilities, horizontal structure and diverse faculty, apply!!!
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Peter Mace
Molecular Cell
8 months ago
Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactions
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Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactions
Schmid and Walter train a classifier that discerns functionally relevant structure predictions in proteome-wide protein-protein interaction (PPI) screens using AlphaFold-Multimer, and they use this confidence metric to curate a database of 40,000 predicted interactions among ∼300 genome maintenance proteins.
http://dlvr.it/TJj26p
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Peter Mace
Pablo Arantes
8 months ago
I’ve just updated the BioEmu notebook to include the powerful LogMD. Now, you can generate equilibrium ensembles and explore the full ensemble directly in the notebook. A huge thanks to Alexander Mathiasen for the support! 🙌 🔗 Try it on Google Colab:
lnkd.in/gcuqd-fT
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Peter Mace
Kate Michie
8 months ago
Uni of Wollongong Cryo EM job closes on Sunday people!
@gokhan-tolun.bsky.social
might be able to answer questions? 🧬🧶
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Associate Research Fellow - SEEK
Seeking an Associate Research Fellow to provide expert advice and support to UOW members of the ARC Training Centre for Cryo-EM of Membrane Proteins.
https://www.seek.com.au/job/82195402?ref=hirer-jobs-list
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Peter Mace
Komander Lab
8 months ago
Exciting news from the lab out today in Science - the structure of human PINK1 on a TOM-VDAC complex!
@wehi-research.bsky.social
add a skeleton here at some point
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Peter Mace
Willow Coyote-Maestas
8 months ago
In this time of chaos - something good! We are excited to share our final (or near final) speaker list for the 3rd UCSF Full Circle Symposium 4/3-4/4 to highlight Native biologists! Please share the word and register to attend the webinar in person! More info:
qbi.ucsf.edu/full-circle-...
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Really exciting to share the peer-reviewed version of our study of the DET1 adaptor for the CUL4 Ub ligase. A cryptic E2-binding site and recruitment mechanism for COP1—another E3!
www.science.org/doi/10.1126/...
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DET1 dynamics underlie cooperative ubiquitination by CRL4DET1-COP1 complexes
A dynamic substrate adapter (DET1) recruits COP1 to Cullin ubiquitin ligase complexes assisted by a noncatalytic E2 enzyme.
https://www.science.org/doi/10.1126/sciadv.adq4187
9 months ago
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Peter Mace
Pierre Maisonneuve
9 months ago
(1/4) 🚀 PhD Fellowship Opportunity
@iecb.bsky.social
@univbordeaux.bsky.social
University of Bordeaux! Looking for talented international Master’s graduates to apply for a PhD fellowship via the UB PhD Scholarship. Two exciting projects in kinase biology & nanobody therapeutics! ⬇️ Please Repost
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Peter Mace
Paul Gardner
9 months ago
My Departments vs Software Accuracy article is finally out -- with great support from the Editors, and some useful feedback from referees.
doi.org/10.1093/bioa...
#benchmarks
#bioinformatics
#genetics
#software
#compsci
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A Bioinformatician, Computer Scientist, and Geneticist lead bioinformatic tool development—which one is better?
Abstract. The development of accurate bioinformatic software tools is crucial for the effective analysis of complex biological data. This study examines th
https://doi.org/10.1093/bioadv/vbaf011
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Exciting to open registration for the IUBMB Focussed Meeting on Emerging roles of (pseudo)kinases! Fantastic speakers in an unmatched location, lots of speaking slots available for ECRS. Interested in kinases or pseudokinases? We would love to see you in Queenstown!
www.ivvy.com.au/event/IUBMB2...
9 months ago
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Peter Mace
Martin Steinegger 🇺🇦
10 months ago
The Foldseek webserver for fast protein structure searches now features a Sankey tree taxonomy visualization and filter, allowing to subset hits by clades. Developed by my talented student
@sunjaelee.bsky.social
. Try it out! 🌐
search.foldseek.com
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Peter Mace
Aniruddha Das
10 months ago
"The current knowledge of ubiquitin signals through a ubiquitin-centric, structural biology lens." Useful resource for ubiuitin-lovers.
www.cell.com/molecular-ce...
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Ubiquitin—A structural perspective
Ubiquitin is a cellular modification that comes in many forms. In this review, Agrata and Komander analyze the 240 available PDB structures of ubiquitin and polyubiquitin, alongside ensemble and molec...
https://www.cell.com/molecular-cell/abstract/S1097-2765(24)01010-4
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Peter Mace
Arne Schneuing
10 months ago
Our paper on computational design of chemically induced protein interactions is out in
@natureportfolio.bsky.social
. Big thanks to all co-authors, especially Anthony Marchand, Stephen Buckley and Bruno Correia!
t.co/vtYlhi8aQm
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Are you doing summer work writing for the Guardian
@ppgardne.bsky.social
?? Or should I say 'Eva'...... The pāua and the glory: cafe’s creation sparks pie mania in New Zealand
www.theguardian.com/world/2024/d...
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The pāua and the glory: cafe’s creation sparks pie mania in New Zealand
Flaky pastry filled with seafood delicacy gains cult status and draws crowds to sleepy beach community
https://www.theguardian.com/world/2024/dec/27/the-paua-and-the-glory-cafes-creation-sparks-pie-mania-in-new-zealand?CMP=share_btn_url
11 months ago
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