Jo Carpenter
@jocarpenter.bsky.social
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✨Maps and memories✨ hippocampal-entorhinal electrophysiologist Moser & Dunn Groups • KISN Norway
pinned post!
At @FENSorg this year? Poster
#PS01-26AM-004
(WED) Presenting my work on remapping of neural populations across the HPC-EC circuit using data from 3 simultaneously-recorded Neuropixels 2.0 probes (CA1-MEC/PaS-Sub) in freely moving rats exploring 5 different rooms over 12 hours!
over 1 year ago
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Jo Carpenter
Emilie Macé
2 months ago
Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
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Jo Carpenter
Dan Levenstein
2 months ago
“If everything is everywhere, why have distinct areas? Here we show that the function of a brain area is more related to how different types of information are combined (formatted) in neural representations than merely whether that information is present.”
add a skeleton here at some point
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reposted by
Jo Carpenter
Matteo Guardamagna
4 months ago
Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in
@natcomms.nature.com
🔬🧠
rdcu.be/evWtz
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Direct entorhinal control of CA1 temporal coding
Nature Communications - Temporal coding in the hippocampus is thought to be key for memory and predictions. Here, the authors show that blocking one entorhinal input affects two aspects of...
https://rdcu.be/evWtz
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reposted by
Jo Carpenter
Jerome Beetz
5 months ago
Amazing study:
@tamir-eliav.bsky.social
from the Ulanovsky lab describes replay events in a large scale environment (200 m tunnel). 🦇
www.cell.com/cell/abstrac...
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Fragmented replay of very large environments in the hippocampus of bats
Hippocampal replays in bats flying in a 200-m tunnel depict short fragments of long flight trajectories, suggesting constraints on the mechanisms and functions of replay.
https://www.cell.com/cell/abstract/S0092-8674(25)00574-4
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reposted by
Jo Carpenter
Yipeng Li
6 months ago
(1/6) Thrilled to share our triple-N dataset (Non-human Primate Neural Responses to Natural Scenes)! It captures thousands of high-level visual neuron responses in macaques to natural scenes using
#Neuropixels
.
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reposted by
Jo Carpenter
8 months ago
Check out my preprint on hippocampal ripple diversity, with
@vitorlds.bsky.social
and David Dupret at the MRC BNDU, where we reveal that distinct CA1 laminar profiles of ripples are associated with different reactivation dynamics:
www.biorxiv.org/content/10.1...
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reposted by
Jo Carpenter
Sarthak Chandra
9 months ago
1/ Our paper appeared in @Nature today!
www.nature.com/articles/s41...
w/ Fiete Lab and
@khonamikail.bsky.social
. Explains emergence of multiple grid cell modules, w/ excellent match to data! Novel mechanism for applying across vast systems from development to ecosystems. 🧵👇
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Global modules robustly emerge from local interactions and smooth gradients - Nature
The principle of peak selection is described, by which local interactions and smooth gradients drive self-organization of discrete global modules.
https://www.nature.com/articles/s41586-024-08541-3
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reposted by
Jo Carpenter
Dr. Catherine Macdonald
9 months ago
Every scientist, long before they were a scientist, was a little kid who stood in front of a fish tank or stared up at the stars or turned over a rock to look at the bugs underneath and said “wow”. On the best days, working in science still feels like that.
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Congratulations Abe and Rich!!
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9 months ago
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Jo Carpenter
Lisa Genzel (she/her)
10 months ago
We are still taking applications!
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Jo Carpenter
Ipshita Zutshi
10 months ago
It’s an incredible feeling to see something you’ve poured your heart into come to life. This work was born from my curiosity about hippocampal “cognitive tuning.” Our interpretation of the environment depends on our actions, constantly evolving as we pursue our goals
www.nature.com/articles/s41...
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Hippocampal neuronal activity is aligned with action plans - Nature
Using high-density electrophysiological recordings, how internally generated cell assemblies are updated by action plans to meet external goals is explored.
https://www.nature.com/articles/s41586-024-08397-7
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reposted by
Jo Carpenter
Misha Ahrens
11 months ago
Our paper on ketamine’s effect on astrocytes and behavior is out in Neuron by Marc Duque, Alex Chen, Eric Hsu, and colleagues
@marcduque.bsky.social
@alexbchen.bsky.social
@ehsu6.bsky.social
, with the Engert, Fishman, & Bergles labs,
www.sciencedirect.com/science/arti...
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Ketamine induces plasticity in a norepinephrine-astroglial circuit to promote behavioral perseverance
Transient exposure to ketamine can trigger lasting changes in behavior and mood. We found that brief ketamine exposure causes long-term suppression of…
https://www.sciencedirect.com/science/article/pii/S0896627324008365
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celebrating another year of excellent science, happy animals, and *happy people* at the kavli ❤️✨
@kavlintnu.bsky.social
11 months ago
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Jo Carpenter
Matthias Nau
11 months ago
Do octopuses dream? In any case, can't get enough of watching them sleep 😴🐙 Look at this symphony of patterns and movements! Incredible.
youtu.be/006DjAixu9E?...
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Do octopuses dream? Brain recordings provide the first clues
YouTube video by nature video
https://youtu.be/006DjAixu9E?feature=shared
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Jo Carpenter
David Tingley
11 months ago
In those animals we didn't observe a correlation between ripples and glucose fluctuations. To me, this strongly suggested pancreatic insulin release is a mechanistic intermediate
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Jo Carpenter
David Tingley
11 months ago
Wow, thanks so much Adrien! It was such an exciting project to work on, and many directions to follow up. Another *really hidden gem (it didn't end up in the paper), we (@jocarpenter and I) treated three rats with streptozotocin which effectively kills beta cells in the pancreas...
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Jo Carpenter
andy alexander
about 1 year ago
Awesome pub looking at the unique role of AD- and M2-projecting RSC circuits from Xiaoxiao Lin et al.
#neuroskyence
www.nature.com/articles/s41...
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Projection-specific circuits of retrosplenial cortex with differential contributions to spatial cognition - Molecular Psychiatry
Molecular Psychiatry - Projection-specific circuits of retrosplenial cortex with differential contributions to spatial cognition
https://www.nature.com/articles/s41380-024-02819-8
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Thankful for a loving family, all of my super funny friends, a happy and collaborative lab environment, and my rat Rafael for giving me some beautiful data tonight 🤩🥰🍗
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12 months ago
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Jo Carpenter
Adrien Peyrache
12 months ago
While this result is really exciting, the paper also contains some hidden gems. Ext Data Fig. 3, for instance, show the power spectrum of ripple occurrence. It reveals that ripple rates fluctuate not only on a 24-hour circadian cycle but also on a 4-hour ultradian cycle. 5/
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Very timely piece. With 3-4 probes per rat and ultra long recordings, I’ve already generated 95TB of data for a single project. Thinking lots these days about how to store and publish all of this… 😬😬 Raw files vs. spike times x behavior or something in between?? Or both?
add a skeleton here at some point
12 months ago
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reposted by
Jo Carpenter
Jon Rueckemann
about 1 year ago
go.bsky.app/LdtUYZS
I created a starter pack for the growing community of hippocampus physiologists that have joined the great migration. Also included the physiology-adjacent. Tell me who I haven’t found yet
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reposted by
Jo Carpenter
Mark Brandon
12 months ago
Now out in Neuron! We benchmark place cell models using a massive CA1 dataset—nearly 70,000 rate maps—collected as mice explore environments with different geometries BVC models perform remarkably well, but we hope this dataset/approach becomes a resource for testing/refining place cell models
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This paper adds to a nice list of papers recently that (broadly) merge brain and body biology: The others one are
www.biorxiv.org/content/10.1...
And
www.nature.com/articles/s41...
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12 months ago
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reposted by
Jo Carpenter
Charan Ranganath
12 months ago
Super-psyched to share this preprint from my student Yicong (Alan) Zheng: "Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation"
www.biorxiv.org/content/10.1...
It's a new biologicaly-based computational model of the entorhinal-hippocampal system. Thread (1/?)
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Recurrent Inhibitory Dynamics in the Entorhinal Cortex Support Pattern Separation
The entorhinal cortex (EC) provides the major input to the hippocampus (HPC). Numerous computational models on the EC propose that its grid cells serve as a spatial metric, supporting path integration...
https://www.biorxiv.org/content/10.1101/2024.11.14.623535v1.abstract
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It’s always a fun lab meeting when the prodigal child @Erik_Hermansen1 returns! (booking conference rooms is not our strong suit)
about 1 year ago
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When you’re unexpectedly in town and all your friends are neuroscientists
about 1 year ago
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SfN 2024 😍
about 1 year ago
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Come check out Moser group posters today at SFN!! ❤️We have: NPX, mini2P, recordings across HPC-EC circuit, remapping, ontogeny of torus, sweeps, all-optical stim, time coding, grid cell hot spot maps, LEC, RSC, SUB & minute scale oscillations! 8:00 AM-12:00 PM 190.01-190.11
about 1 year ago
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At @FENSorg this year? Poster
#PS01-26AM-004
(WED) Presenting my work on remapping of neural populations across the HPC-EC circuit using data from 3 simultaneously-recorded Neuropixels 2.0 probes (CA1-MEC/PaS-Sub) in freely moving rats exploring 5 different rooms over 12 hours!
over 1 year ago
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@MartinBjerke_ presenting his PhD work (with @adric_dunn) using some classic @Drake memes at @kavliYROCK ‘s annual NeuroSys symposium !! 🧠
over 2 years ago
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pre-presentation sun exposure ☀️ come see our recent work from the Moser group at SFN YY1-YY5 at 1pm today Unpictured: new group leader @soledad_gcogno
about 3 years ago
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At SFN 2018 in San Diego, I met my future PhD advisors @MayBrittMoser @EdvardMoser and future partner @davidwtingley 🥰 I’m super stoked to be back in my old college town this year to present Part 1 of my PhD work, catch up with old friends, and see some new science !! 🧠
about 3 years ago
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celebrating successes in the moser lab! congratulations on the acceptance of the miniscopes paper @WikiZong @HorstObenhaus @EmilieSkytoen @NienkeLdeJong @HannaEneqvist @RubenDVale @MayBrittMoser @EdvardMoser and marina 🤩
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over 3 years ago
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congratulations @davidwtingley on an awesome PhD defense! you are a brilliant scientist and the best partner.
almost 5 years ago
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did I just watch a presidential debate or an episode of the real housewives?
about 5 years ago
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So far, my first year of grad school has consisted of: - moving to a new continent - being in a *very* long distance relationship - being emotionally tested by various physics and math classes - recording some place cells - a global pandemic
over 5 years ago
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I’m looking for a few comp. neuro papers to discuss with my signal processing buddies that use laplace/fourier transform- any suggestions? Shankar & Howard 2012 is up first :)
almost 6 years ago
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Celebrated my last day in the McNaughton Lab @ucicnlm yesterday. I’d like to extend a big thanks to all members of the group for being supportive colleagues, patient mentors and my best friends. I’ll miss you all dearly. Next stop, Moser Lab @KISNeuro!
over 6 years ago
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Monkey pool party at our place in Kuta 😂🐒
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over 6 years ago
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Took a slight detour on our way down to Taormina @davidwtingley
over 6 years ago
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After a long week of
#EpicFails
, something kinda worked out! I’m being warmly welcomed to the world of grad school.
over 6 years ago
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My people!! McNaughton Group photo 2019 ^_^
over 6 years ago
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NTNU or Hogwarts? So stoked to be here in Trondheim!
almost 7 years ago
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you reached the end!!
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