The President's fiscal year 2027 Budget was released today. Important---Important---Important The President's Budget is always fundamentally a political document that Congress may or may not (usually not) take very seriously. www.whitehouse.gov/wp-content/u... 1/9

Today is the anniversary of the April 1 RIFs at NIH and HHS. Thinking of my colleagues who lost their jobs last year. These cuts did no improve efficiency. They undermined the functioning of our government.

Just a reminder that 1yr ago today many dedicated NIH employees received RIF notices and started the process where many others were told they must leave their positions/ICs after years of service. The pain felt across the scientific community in the last year is also felt by those serving it.

One incentive for being a study section member for NIH is “continuous submission.” Or the ability to get extra time for submitting grants when you are a peer reviewer. NIH is terminating this in August.

Cancelling continuous submission for reviewers seems like just about the worst possible idea. grants.nih.gov/grants/guide... Unless of course breaking the system is the point. Many PIs are already quietly boycotting review. Some not wanting to lend credibility to an increasingly corrupted NIH…

Whelp. NIH just got rid of continuous submission completely. Because it’s “too much work” for them 😩. This is baffling. It doesn’t take months to assign a grant to a study section.

I showed this graph in class yesterday on how measles cases in the United States plummeted dramatically after the vaccine was licensed in 1963. It’s not subtle and I could not resist observing: “This stunning design in measles cases was not thanks to vitamin A. It was not due to beef tallow.”

New to Plasmidsaurus? They're offering the Addgene community their first three sequences free with code ADDGENE. https://twp.ai/4iwdRq

This is what democracy looks like. Now, prepare to VOTE and get everyone you know to do likewise.

📣 💰 Hematology funding alert! Travel awards are available from the NIDDK-sponsored Cooperative Centers of Excellence in Hematology (CCEH) to support early career scientists who are presenting at upcoming conferences! Due 4/15 👇👇👇 cceh.io/funding/cceh...

It was delightful to have a chance to catch up with @nozomi-ando.bsky.social during her visit to UB and hear about the amazing work happening in her group @andolab.bsky.social! The new work untangling allostery in ATCase is🔥! #structuralbiology #biochemistry #allostery

Stories like this make me feel that it’s all worth it. Even if stress during the current times is overwhelming, to have even a little of an impact like this pushes me to endure. I hate that the current times means mentors like this aren’t being celebrated and uplifted in the way they deserve.

Trust me--read this. You'll be glad you did. and thank you Dr. Bennet for writing it. 🧪

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

1) The Herzik lab is excited to announce our newest preprint in collaboration with the Grotjahn lab! We have developed a surfactant cocktail that seeks to overcome one of the more nefarious problems in #cryoEM, Air-water interface (AWI)-induced damage and preferred orientation (PO).

Happy Noh Ruz to those who celebrate! It’s a rough one this time, but we can hope for better and try to bring it.

New @sloanfoundation.bsky.social grants: Exemplary Pathways to STEM Graduate Education. Up to $500,000 for orgs focused on helping remove obstacles for undergraduates who want to pursue advanced STEM degrees. Deadline is June 1. Please share & apply if this is you! sloan.org/programs/hig...

NIGMS is signed onto the F31 NOFO. grants.nih.gov/grants/guide...

Today we’re welcoming our next #cryoEM short course training cohort. Although this week is SPA focused we hope to introduce the trainees to all the structural science we do at the Center. nccat.nysbc.org/activities/c...

The #NIH comprises less than 1% of the federal budget. 80% of that is allocated to universities and research institutions. That $$ ($36B) yielded $94 BILLION in new economic activity in 2025.

OK scientists--now let's see what you've got for a "good day in the field stories"?! There's got to be some amazing tales you can share:)

🚨All of you scientists submitting grants & papers: don't make me have to blow up your figures on my 43inch monitor to try to decipher your data! Even when it is magnified I can barely read details because the PDFs have no resolution. RULE #1 for grants and papers....don't piss off your reviewer!

Samantha Arnone is presenting her poster today at the @asbmb.bsky.social meeting! Check it out if you are at the meeting!! Congrats to Sam on receiving University at Buffalo Experiential Learning Network travel award to attend the conference and present her research! 🎉

It's official - I am now TENURED at the University at Buffalo in the Department of Biochemistry! Grateful to the amazing people in my group, to my colleagues & collaborators, & to my mentors! So excited to be sharing this news! #tenure #science #research #celebrate 🎉 🍾

Ok, now we are ready to rally!

Dorothy Crowfoot Hodgkin, biochemist & a trailblazer in crystallography, she established the biomolecular structures of insulin, vitamin B12, & penicillin winning the Nobel in Chemistry in 1964 #WomensHistoryMonth #WomenInStem #WomenInScience

This is why it's not enough for Congress to just appropriate funds to scientific agencies. How the funds are or are not spent and when they are spent needs to be enforced. The administration is playing games with our taxpayer dollars, when they should be going towards scientific innovation.

The Lancet is not holding back in its latest issue. "The destruction that Kennedy has wrought in 1 year might take generations to repair, and there is little hope for US health and science while he remains at the helm." 👉 www.thelancet.com/journals/lan... @thelancet.com

Today, my mom asked me if I ever considered publishing in Science Magazine to reach a broader audience... Thanks, Mom. #oceanography 🌊🤦‍♀️🙄

Great to see Levi McClelland and meet Cindee Yates-Hansen from the University of Montana Center for Biomolecular Structure & Dynamics at Biophysical Society #BPS2026

@doctheagrif.bsky.social on storytelling in science during the President's Symposium: Communicating the Value of Biophysics in a Changing World at #bps2026 @biophysicalsoc.bsky.social Love it!

Excited to be at #bps2026 for the 1st time in a long time! @jeremymberg.bsky.social currently speaking in the President's Symposium: Communicating the Value of Biophysics in a Changing World

Today's President’s Symposium: Communicating the Value of Biophysics in a Changing World features speakers who will discuss perspectives on the current crisis in US investment in science, and approaches for conveying the value of research to human health and prosperity.https://buff.ly/qcRp51M

During her PhD, Jenny found something unexpected: biofilm-deficient P. aeruginosa mutants were just as tolerant to antibiotics as the WT when grown in our cystic fibrosis lung model. But why? #MicroSky 1/n

Stand Up for Science Rally - March 7th, 2026 Buffalo NY - Niagara Square Come one, come all! 🧪🌎 www.facebook.com/events/42518...

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...

North Carolina lawmakers have voted to remove all college campus voting sites. Specifically at the largest HBCU in the US NC A&T. They now have to walk 30 minutes to their nearest polling place. Students are protesting this - pls share and support. www.tiktok.com/t/ZThx29BJ9/

M​auro Gemmi et al.: Round robin on structure analysis from 3D electron diffraction data @stockholms_univ@stockholms_univ@stockholms_univ@stockholms_univ@stockholms_univ@uni_mainz@unibasel@uni_mainz...##IUCrhttps://journals.iucr.org/paper?S205225252600045X

Lots of signage and some cool labels to decorate our badges with. Not the usual "speaker", "organizer", or "exhibitor" labels, but "More of a Comment than a Question", "Armchair Astronaut", and "Runs on Coffee". #AAASMtg

Co-chairing IUCr 2026 MS-012 “Next-generation validation metrics for macromolecular structures” with Deborah Harrus (@deborah83.bsky.social)! Focus: new validation concepts/methods/best practices across all methods. Submit abstracts by Feb 15; early-bird reg by Mar 31. www.iucr2026.org

Stories from #WomenInScience who changed how we visualize #proteins: Ahead of her 85th birthday, Jane Richardson (Duke Univ, @biophysicalsoc.bsky.social president 2012-13) discussed her life from making a telescope to developing ribbon diagrams for 3D protein structure www.nature.com/articles/s41...

One thing I just learned from Bad Bunny is that very careful preparation and attention to every detail, moment by moment, in crafting a presentation can do wonders

Coffee and improved cognition, reduced dementia >130,000 people followed 37 years Benefit seen only with caffeinated coffee or tea and most pronounced ~2 cups/day @jama.com ☕️☕️https://jamanetwork.com/journals/jama/fullarticle/2844764

Lastly, this one is for all of my fellow microscopists. Of all realms/modalities. A friend of mine wrote this a decade ago. She's a magnificent microscopist and I love her to pieces.

We are organizing a mini-symposium on "Membrane and Organelle Dynamics" at ASBMB 2026! #ASBMB @asbmb.bsky.social @aydinlab.bsky.social and I have put together a fantastic lineup of speakers for Day 1 morning. Come learn about some cutting-edge research in the field.

Prohibitins aren’t hanging out just anywhere in the membrane — they prefer the 💁‍♀️💎✨VIP section💅🪩🥂 Lab all-star @mmedina300kv.bsky.social maps these microdomains using cryo-ET + surface morphometrics. s/o to #teamtomo #cryoET co-authors @hamid13r.bsky.social @attychang.bsky.social @baradlab.com

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Every American needs to watch this:

Unquestionably the result of combined effort from all current and former lab members, support from colleagues @CSU and @CU, and support from @hhmi-science.bsky.social and NIH over decades. A heartfelt 🙏 to my nominators and of course @vilcekfoundation.bsky.social. vilcek.org/prizes/prize...

#ProtistsOnSky no 'swimming' by 𝘝𝘢𝘮𝘱𝘺𝘳𝘦𝘭𝘭𝘢, definitively no 'staying still'. just a relaxed walk towards the lunch...