Thanks @contagionlive.bsky.social for letting me put in some unscripted words UC San Diego is the ideal place to receive your dream education or pursue a faculty career in collaborative medical or pharmaceutical sciences @ucsandiego.bsky.social @ucsdmedschool.bsky.social @ucsdpharmacy.bsky.social

Before coming to NIH, Collins identified the gene that is mutated in cystic fibrosis (CF). Years later, this discovery led to the development of an innovative therapy for CF that's saved countless children. This is why we fight. www.nejm.org/doi/full/10....

As a #childhoodcancer doctor, I'm proud to be able to advocate for children with cancer in any way that I can. Here is a piece that I recently wrote for #TheDetroitNews, who kindly published it. #PEDCan #CANSky www.detroitnews.com/story/opinio...

This rapid action by the Prebys Foundation is the kind of thing I hope other regional philanthropies are doing. It isn't the entire solution by far but it is great to see them chipping in to help investigators in the San Diego academic science community. www.prebysfdn.org/stories/blog...

Beyond taking #healthcare away from millions of kids, families, and the elderly, the Budget-Busting Bill would mean the loss of thousands of jobs in hospitals, research centers, nursing homes, clinics, doctors’ offices. www.nytimes.com/interactive/...

“I represent 67,000 pediatricians, and let me be clear: this bill will devastate children’s health,” said Dr. Susan Kressly, President of @ameracadpeds.bsky.social “Kids are 22% of our population—but 100% of our future. We cannot afford to fail them.” Call your senators and demand a NO vote.

The promise and problems with multi-cancer early detection tests by Sid Mukherjee @newyorker.com www.newyorker.com/magazine/202...

Nice to see this important translational hurdle- crossing the BBB- highlighted in Nature! Of note is the point that it would be ideal to not only cross the BBB, but deliver therapeutics specifically to the CNS site of disease which current brain shuttles don’t do. Stay tuned:) #SelectinTherapeutics

Nature research paper: The pivot penalty in research https://go.nature.com/4dDz2bL

Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer www.nature.com/articles/s43...

My quote of the day If an elderly but distinguished scientist says that something is possible, he is almost certainly right; but if he says that it is impossible, he is very probably wrong. Arthur C. Clarke

CBTN offers pediatric brain tumor data and samples to researchers worldwide for free. Request these resources to accelerate discoveries for kids: https://monkeylink.co/5c6c96 #WeAreCBTN #OpenScience

Cuts to NIH funding have dire consequences! Neuroscience Professor Robert Greene shares why efforts to treat brain disease will suffer due to recent changes in U.S. government policies. #Neurosky #AcademicChatter

Medicaid Covers • 42% of all children nationwide • 77% of children living in poverty in the U.S. • 44% of children and youth with special health care needs nationwide • 41% of births in the U.S. • 37% of U.S. children with cancer • 99% of children and youth in foster care

A Characterization of the Immune Cells in Immunocompetent and Immunodeficient Mice with Orthotopic Brain Tumors. https://www.biorxiv.org/content/10.1101/2025.04.29.651335v1

Cell classification should be based on more than just DNA

Toxicity in phase III oncology clinical trials is often incompletely reported - Fumiko Ladd Chino @fumikochino.bsky.social oncodaily.com/opinion/fumi... #OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

This bottleneck in research funding threatens research that took decades to build, as well as the cures of tomorrow. Publicly-funded research is the highest economic yield there is, with 2.5X of economic gains for every $. Call your Senator and Rep to ask them to protect federal research!

The NIH grant that has supported 38 years of training the best pediatrician-scientists in the country (I’m a proud former recipient) was cancelled. It was just approved for a 5 year renewal. The PSDP has supported the careers of many NIH-funded pediatrician-scientists and thought leaders

Pediatric research. When grants are pulled, the infrastructure suffers www.wcvb.com/article/bost...

On the front page of @cnn.com is a feature on how #NIH funding cuts might impact #childhoodcancer. Thanks to MJ Lee for spotlighting this issue, and I was glad to be able to contribute. These kids deserve the best, not cuts! #CANSky #PEDSky www.cnn.com/2025/02/25/h...

Who benefits from US funding uncertainty? Hours after posting this, I got an email inviting me to China with a “package to support my research for 20 years.” Apparently, generous offers are available to all good scientists!🧪🧠

American science is under attack Opinion piece by Dr Harold Varmus, Nobel Prize winner, former director of the #NIH and the #NCI 🧪 “Perhaps what’s most disheartening is what feels like the absence of widespread opposition to this unraveling” www.nytimes.com/2025/02/14/o...

The NIH’s new imposed standard indirect cost rate threatens life-saving brain & behavior research that benefits millions of Americans. SfN, with other scientific organizations,urge reversal of this policy & implore Congress to protect critical research infrastructure. Full statement: bit.ly/4jVJnCL

how the NIH contributes to the economy in my home state — find yours www.unitedformedicalresearch.org/nih-in-your-... dollars cut is a 2.5x economic return nullified, many good jobs lost, and locally economies and their healthcare weakened no savings to our country, but rather incredible losses

Science is absolutely key to the US's success but this government's intention to now dramatically reduce the part of the federal grants that go to the university (in addition to the researchers; the "indirects") is like removing the unseen roots of a tree and expecting it to continue to flourish.

“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.” www.researchamerica.org/2023-oped-us...

As a pediatric hematologist oncologist I’d like to remind y’all that federal funding for ALL childhood cancers combined is only 4% of overall cancer research funding. CHILDREN with CANCER. Who deserve every single chance they can get yet are shown over and over how little our society cares.

This is a really exciting paper on improving therapeutic index using dual-payload nanomedicines for combination therapy in cancer. Congrats Satchi-Fainaro lab and team! pubmed.ncbi.nlm.nih.gov/39671487/

Limited activity in CDK4- or CDK6-amplified tumors, although central nervous system tumors warrant future investigation from this phase II trial of palbociclib in cancer patients. Results from NCI-MATCH ECOG-ACRIN Trial EAY131 Subprotocol Z1C @uofpenn.bsky.social aacrjournals.org/clincancerre...

A number of #AYA cancer survivors experience insurance and financial hardships, including foregoing medical care due to financial constraints, problems paying medical bills, and difficulties accessing loans or insurances. #survonc #ayacsm link.springer.com/article/10.1...

Happy Thanksgiving everyone! Enjoying the Rady Invitational holiday tournament with some big time college hoops teams in town. Purdue/NC State & Ole Miss/BYU. Next year - Kansas/Florida/Wisconsin/Providence are scheduled to play!!!!