Congratulations @philipschoene.bsky.social on defending his Master’s thesis on the supremacy of mechanics in Hydra regeneration from aggregates of dissociated cells. Expertly guided by @anaisbailles.bsky.social. #experiment and #theory #LoPaTs @mpi-cbg.de @poldresden.bsky.social #stuffthatmatters

✨ Post-doc opportunity in axon biology, funded by #ATIP-Avenir! 👀 We are looking for an enthusiastic post-doc to join our team at @ibdm.bsky.social to explore translation dynamics in axon regrowth, using live imaging approaches. Apply at: emploi.cnrs.fr/Offres/CDD/U... Thank you for sharing! 👋 🙏

Hydra are ~basically~ immortal. Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads! This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️

Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.

[PUBLI] Observing muscle growth brick by brick A research project at the @ibdm.bsky.social, led by Clément Rodier, has recently challenged long-standing scientific hypotheses about how muscles elongate during development, thanks to advanced #microscopy. 🔗 Our article in comments

Females are larger than males. How? Here is one solution- they have MORE nuclei in their flight muscles and grow LARGER heart and fat body cells with MORE ribosomal mRNAs. Fun collaboration of @jeromeavellaneda.bsky.social with @soumitrakp.bsky.social & Brian Oliver www.biorxiv.org/content/10.1...

Mechanosensation and fast reorientation of ciliary structures: Marvin's work on the surprising locomotion capabilities of Trichoplax, an animal without neurons! www.biorxiv.org/content/10.1...

Our beautiful Hydra made the cover!!! 😍😍😍 An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de Actin fibers in blue, nuclei in orange.

Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)

Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...

Katia took the initiative to start a Xenopus project in the lab a few years ago —and now her work is highlighted by Development! Huge congrats, Katia!

🚨 2 × PhD positions @EPFL! 🚨 Help us push the boundaries of fluorescence microscopy - DNA nanotech, custom optics & spatial omics in Lausanne 🇨🇭. Start Jan 2026. Send CV + motivation + 2 refs → [email protected] #PhD #Hiring #microscopy #SuperResolution #SpatialOmics #DNAPAINT #FLASHPAINT

Microtubules: the architect of muscles. Watch how microtubules transport mitochondria in proximity to energy consuming sarcomeres in muscles of flies and mice. @jeromeavellaneda.bsky.social @nunoluis.bsky.social @ibdm.bsky.social with @gomeslabo.bsky.social www.sciencedirect.com/science/arti...

Congratulations @alicegros.bsky.social @jules-vanaret.bsky.social & @dunsingvalentin.bsky.social for this huge team effort! Gastruloids morphogenesis is so fascinating and now we can explore and travel through them in 3D & at cell resolution day and night 🤩

🥇Sham Tlili has been awarded the CNRS 2025 Bronze Medal! She studies how physical forces shape living tissues by using mouse stem cell models known as gastruloids. A unique blend of physics & biology. 🔗 Read more: www.ibdm.univ-amu.fr/sham-tlili-w...

#LoPaT @anaisbailles.bsky.social bringing up the wonders of #Hydra, #physics, disorder to order transition and tissue mechanics to #TCTeAC

Beautiful work!

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social www.science.org/doi/epdf/10....

Super proud of superstar postdocs @nerlielisa.bsky.social and @liujinghui.bsky.social for our lab's most recent preprint! We uncover how wound-induced electrical currents are generated and transmitted in tissues, triggering proliferation, essential for organ #regeneration #bioelectricity #QBio 👇

New lab paper out! 😀 We describe a new benchtop technique to isolate microRNAs from various cell types in a complex tissue (like the developing CNS). This is a fruitful collab with the Cremer lab from @ibdm.bsky.social journals.plos.org/plosgenetics... 1/n 🧵

Our new call for VIB.AI group leaders is online! Junior and senior positions available to develop innovative ML methods in biology. With professorship at CS or Medical Faculty. Deadline 14th June. DM for more info.

The @embo.org practical course on #lightsheet #microscopy is back! Join us in #Dresden for 2 weeks with #your #samples, try the complete line-up of #lightsheet microscopes, tackle big data image analysis, sample prep, OA hardware & much more Apply now! Repost 🙏 meetings.embo.org/event/25-lsm

⏳ Don’t miss out ⏳ 🕊️ Early bird registration for Shaping Life 3 is open until April 1, 2025!  🌊 Join us in Cassis, France, June 3-6 for a top-tier developmental biology conference by the sea.  Secure your spot now 👇

📢 Abstract submission deadline: April 1, 2025!  ✨ Submit your abstract before April 1 and join us in Cassis, June 3-6, 2025, for cutting-edge discussions in developmental biology. @sfbd.bsky.social Submit abstract here 👇

🚨This week, many Columbia scientists lost grants that funded over half their annual income. Others will no longer be able to do research that helps treat thousands of sick patients across the US. "It hurts," they told me. My story for @nature.com 🧪 www.nature.com/articles/d41...

Thrilled to see the new version of our work out! A fantastic collaboration with @frankschnorrer.bsky.social @steinaerts.bsky.social @pierremangeol.bsky.social, Nikolai and Gabriele to do spatial transcriptomics in the adult fly -- huge thanks to everyone for bringing this to the finish line! 🙏🪰

Spatial transcriptomics in fly brain and body. Wonderful collaboration with @steinaerts.bsky.social led by @jasperjanssens.bsky.social @pierremangeol.bsky.social Nikolai Hecker & Gabriele Partel - look at mRNA patterns in muscles and brains spatialfly.aertslab.org elifesciences.org/reviewed-pre...

mitoXplorer 3.0 has been published in the JMB issue 'Computational Resources': doi.org/10.1016/j.jm... Check out our web-tool to analyse bulk- and single-cell RNA-seq data from a mitochondrial perspective. mitoxplorer3.ibdm.univ-amu.fr

Is it possible for a FP to bleach much faster in point scanning confocal microscopy than in spinning-disc confocal ? To the extent that it's barely usable in point scanning but works fine in SDC? A user seems to have observed this with an RFP variant - (and I tested 3 point scanners...).

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

We just released and uploaded a new version of *Mastodon*, the large-scale tracking and track-editing framework for large, multi-view images. Mastodon is available via Fiji, via a dedicated update site. mastodon.readthedocs.io/en/latest/do... Below is a thread that survey some of the novelties ⏬️

Finally had a bit of time to play with multi-GPU deconvolution. Using @truenorth-ia.bsky.social and @haesleinhuepf.bsky.social previous work. Here it is in action in #BigDataViewer using async and lazy processing. Look at the two poor laptop GPUs going as fast as they can:

Mangeol, P., ..., & Lenne, P. F. (2024). The zonula adherens matura redefines the apical junction of intestinal epithelia. Proceedings of the National Academy of Sciences of the United States of America, 121(9), e2316722121. #EpithelialMechanics https://www.pnas.org/doi/10.1073/pnas.2316722121

Together with Sophie Brasselet we have an exciting PhD project to decipher the nanoscale organization of proteins the during muscle development. It brings fundamental questions in biology and the latest advances in single molecule microscopy. Apply on the CENTURI website: shorturl.at/g935T

How insects unfold their wings ! rdcu.be/d28vT

New followers = time for a fresh intro! 👋 I’m Christopher, a reproductive biologist and group leader at @IBDMmarseille 🇫🇷 My lab uses #LiveImaging to explore how the dynamic #ovary produces healthy #eggs 🔬🥚 Please share & follow as we push the boundaries of #fertility research! 🔗 bit.ly/3zQPEh7

Happy #3DThursday everyone! #Drosophila lovers -- check out this beautiful #microCT scan of the adult Drosophila, imaged by Dr. Todd Schoborg at UWYO! I've shown this data to hundreds of people, and most don't know what these structures are... do you?