We had a great time sharing 3D data from our pipeline at the Massachusetts Life Sciences Center's Convening of the Cores! Thanks to Sony and syGlass for making our data pop on the Spatial Reality Display. MA researchers, check out LifeCanvas tools at cores near you: bit.ly/3O8SgO0

❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ. 🔬: Miltenyi Ultramiscroscope 🥼: Pam Rios Coronado, @pamrc.bsky.social 🏛️: Red-Horse lab @stanford.edu 🎬: #syGlass

Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples. #MedicalImaging #3DImaging

The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass! @alleninstitute.org #3DThursday #DataViz #VR

For #3DThursday, a skeleton shrimp imaged on a Flamingo light sheet microscope — a modular, traveling #LSFM built to bring the microscope to the biology.🔬🦩Fast 3D imaging, low phototoxicity. 🥼: Carsten Wolff @carsten-wolff.bsky.social 📝: huiskenlab.com/flamingo/ 🏛️: @morgridgeinstitute.bsky.social

🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm 🔬: Bruker SkyScan 1172 🏛️: UWyoming 🎬: #syGlass, v2.5.0

2025 took us around the world 🌍 From Zurich to Beijing, London, Paris, Montreal, all over the Americas, we explored scientific datasets in VR with the researchers who created them -- and pushed #syGlass to new limits for 3D analysis. On to 2026. 🔬✨ #3DThursday #Microscopy #ScientificImaging

Nice feature from NVIDIA on #syGlass at the MBL! Exciting to see AI, RTX GPUs, and VR coming together to explore massive 3D brain datasets, with high school students contributing to ongoing, cutting-edge neuroscience research. @mblscience.bsky.social blogs.nvidia.com/blog/mbl-hum...

#syGlass v2.5.0 is out! 🎉 New depth-aware colormaps, expanded file formats (NRRD/MRC/TCF/OME-Zarr v3), better #VR segmentation tools, and upgraded narration workflows — all focused on making #3Ddata easier to explore and share. Blog: www.syglass.io/blog/syglass... #Microscopy #Imaging #3DThursday

Guest lectured at UNH–Manchester’s Techniques in Microscopy this week, and the students are already thinking like researchers. Early exposure to real #Microscopy and #ImageAnalysis tools makes all the difference. 🔬: Zeiss LSM 510 🥼: Students + Prof Mark Scimone 🎬: syGlass.io #3DThursday #syGlass

One year of #3DThursday! Revisiting our first specimen, a Pekin duck: thanks to this community we learned she was Beaker, a rescued duck from Utah who later contributed to science. 🔬: #CTScan, Scarlet Imaging's BriteVu 🥼: Scott Echols 🎬: syGlass.io 🦆📸: credit TIFOtter #Anatomy #syGlass #SciComm

Stoked to be back in San Diego for #sfn25 with syGlass and the rest of the team. This week, we're showing off our new AI based axon tracer and the new Sony Spatial Display. Come visit us at booth 813!

Exciting News! 😎 syGlass is proud to announce our new collaboration with Sony, featuring their revolutionary glasses-free 3D Spatial Reality Display. Experience the future of visualization at the 2025 Society for Neuroscience conference. Stop by our booth #813 to see it in action! #sfn25 #sfn2025

For #3DThursday we’re introducing Dynamic Depth color mapping! It encodes distance with smooth depth-aware gradients so layered structures pop without losing context. 🔬 #MicroCT of a P1 mouse 🥼 Hsu Lab, Baylor, @cwloganhsu.bsky.social 🎬 syGlass.io #Microscopy #SciComm #3DVisualization #syGlass

Expansion with Magnify for #3DThursday this week! This mouse brain tissue was imaged using Magnify Biosciences, Inc. expansion microscopy — a simple, low-cost way to achieve nanoscale resolution with a standard confocal.

it was great to present syGlass, Inc at CACIE, part of the largest international educational conference in China, with Kenan Sener, Ed.D. Very grateful for CAEIE for hosting me for this week in Beijing. ❤️ lnkd.in/g8KQMa8x

Taking over #3DThursday while Brandy Freitas @brandy-syglass.bsky.social is out of office for some adventures! 🦇: Rousettus aegyptiacus stained in 10% Lugol’s iodine for 3 months 🔬: PerkinElmer Quantum GX microCT 🥼: @acsharp.bsky.social 🏛️: University of Liverpool’s Centre for Preclinical Imaging

Absolutely amazing to hike the Great Wall of China. Truly an engineering marvel and an amazing historic achievement.

It's great to visit my good friend Alain Chédotal for an extra special lecture of tissue clearing and light sheet microscopy -- at Faculté de Médecine Lyon Est, Université Claude Bernard Lyon 1 + Hospices Civils de Lyon - HCL @hospicescivilslyon.bsky.social

The #mesoSPIM symposium really opened my eyes to the power of open source hardware. I've highlighted some of the surprising outcomes in a new blog post: How Open Source Microscopy is Solving the Funding Crisis: Insights from the mesoSPIM 10-Year Symposium www.syglass.io/blog/how-ope...

I have really neglected Bluesky. I'm going to try to add my backlog of adventures here now. To start, #mesoSPIM symposium in Zurich! Amazing conference, amazing people, amazing talks!

One of my favorite #syGlass keyframes yet!

👀 #3DThursday: Cross your eyes to see this super res pollen dataset in 3D! Good old fashioned stereo pairs in #syGlass bringing science to life. 🌿✨ 🔬: Zeiss LSM 980 with Airyscan 2 🥼: Nat Prunet, @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core: tarheels.live/biologymicro... 🎬: syGlass.io

this is so freaking cool! 🤩

Just woke up from a social media pause and the first thing I see is an incredible footage of a sperm whale casually cruising with a giant squid in its mouth ?? 🦑 🌊 🌿

🦐 High-res microCT of #Parhyale hawaiensis for #3DThursday! A powerful crustacean model for studying limb development, regeneration, and evo-devo. 🥼: Nipam Patel & Andrew Gillis, 2017 🏛️: University of Cambridge @cam.ac.uk 🎬: syGlass.io #Parhyale #MicroCT #DevBio #EvoDevo #ModelOrganisms #syGlass

Pollen diversity #3DThursday!🌼🌾 Thanks to Nat Prunet's careful microscopy, we see ridges, spikes & pores that reveal how plants spread & survive. 🔬: @zeiss-microscopy.bsky.social LSM 980, Airyscan 2 🥼: @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core 🎬: syGlass.io v2.4.0 #syGlass

Chicken balancing for #3DThursday!🐔 These utricle hair cells sense gravity & straight-line motion. We segmented them with #CellposeSAM in #syGlass. 🥼: Stefan Heller Group 🏛️: Stanford @stanfordmedicine.bsky.social 🎬: syGlass.io v2.4.0, out now! #Neuroanatomy #Microscopy #3DVisualization #SciComm

Another great conference at M&M (Microscopy and Microanalysis) means another annual interview with the fantastic Eric Jay Miller! Check out the short interview here: www.youtube.com/watch?v=herZ...

Automated Segmentation by Cellpose-SAM using syGlass for #3DThursday! This took about 30 minutes to run on one of the gaming laptops. Crazy. 🔬: Synchrotron #MicroCT 🥼: Keith Cheng, MD, PhD, @pennstateuniv.bsky.social 📝: #CellposeSAM www.biorxiv.org/content/10.1... 🥽: syGlass.io v2.4.0 -- out soon!

really nice cochlea whew!

If you're attending 🎉 Microscopy & Microanalysis 2025! 🎉 definitely say hello at booth 1228 and try out the latest workflows in syGlass

A #microscopy mystery for #3DThursday!🌾 What is this? 🔍 Things that I know: it is a #plant, it was imaged on a Lumafield #microCT, and the color is a LUT (look up table) that I applied in #syGlass and has nothing to do with the organism (microCT comes in as grayscale). Help! #SciComm

The Confetti Cannon was the work of one of our UC Berkeley @ucberkeleyofficial.bsky.social summer interns!

Happy 4th for #3DThursday! 🎉 Do I occasionally forget and then remember ecstatically that we have a confetti cannon in the syGlass room? Yes, yes, I do ... #syGlass #VRScience #Microscopy #SciComm

Finally plants for #3DThursday!🌽 A maize root tip, imaged using #microCT, from the Topp Roots Lab. 🔬: @zeiss-microscopy.bsky.social Versa 520 XRM 🥼: Keith Duncan @cygnusplantxray.bsky.social 🏛️: Danforth Center @danforthcenter.bsky.social 📝: academic.oup.com/plphys/artic... 🎬: syGlass.io #syGlass

I am incredibly honored to represent the NCSSS at the China-US STEM and AI Education Seminar. Fantastic to share our work at syGlass on the forefront of immersive science, education, and #AI. I look forward to working with our Chinese allies in connecting students and scientists around the world.

Get your 3D glasses out for #3DThursday! And click the link below to see syGlass on the really big screen at the @mit.edu MIT Museum last week. (guys it's my first syGlass blog ...) 📝: www.syglass.io/blog/a-night... 🥼: Kory Evans @sternarchella.bsky.social , Rice University 🎥: syGlass.io #syGlass

LIVE sea urchin larvae for #3DThursday! Catch me at the MIT Museum tonight at AfterDark and see it in person. 🔬: @brukercorporation.bsky.social TruLive3D 🥼: Amro Hamdoun @hamdounlab.bsky.social ‬, Tzer Han Tan's @tzerhan29.bsky.social group at UCSD 🌌: Painted Sea Urchin 🎥: syGlass.io #syGlass

Very happy to add my signature to the Bethesda Declaration and #standupforscience www.standupforscience.net/bethesda-dec...

✨ Heading to @mdibiolab.bsky.social next week for the LSFM course! Here’s some stunning lightsheet data from @erturklab.bsky.social 🔬: Blaze Ultramicroscope, LaVision Biotech 🥼: Hongcheng Mai, Jie Luo, Helmholtz Munich 📝: pmc.ncbi.nlm.nih.gov/articles/PMC... 🎬: syGlass.io #3DThursday #LSFM2025

It's #3DThursday! Just a little feature focus this time, checking out syGlass Narrations. An excellent way to record yourself walking through 3D datasets, explain your findings, and let your audience pause, explore, even move around you while you talk. 🥽: syglass.io #VR #Microscopy #SciComm #EdTech

For #3DThursday, whole mouse liver imaged with #mesoSPIM light sheet microscopy! Showing how structure meets function across the organ. 🥽: syGlass.io 🥼: Hei Ming Lai 📝: INSIHGT -> www.nature.com/articles/s41... 🏛️: Chinese University of Hong Kong #LightSheet #SciComm #3DImaging #syGlass

In the age of AI annotation tools, why use VR to segment or track objects in your image volumes? My answer + more on new features from our spring release of syGlass: www.syglass.io/blog/syglass...

🔬 For #3DThursday: syGlass v2.3.0 is here!🥽 Improved time series tracking, 📊 histogram view for thresholding, avatar preview before narration, 🕶️ real-time anaglyph rendering, and narration editing. More upgrades + fixes inside. 📬 47483437.hs-sites.com/syglass-v2.2.3 #Microscopy #VR #SciComm

Traveled in Moab, Utah by foot, ebike, and camper van 👍

For #3DThursday, a cleared axolotl on a line confocal! 🥽: syGlass.io 🔬: Dual-View Line Scanning Confocal: www.mbl.edu/research/res... 🥼: @ryliewalsh.bsky.social, @mblscience.bsky.social 🐉: @murawalalab.bsky.social, @mdibiolab.bsky.social 🏛️: MBL Center for Innovation in Imaging and Image Analysis

Comparison may be the thief of joy, but in devbio it’s how researchers understand how life takes shape. Excited to be at SDB Northeast this weekend! www.sdbonline.org/nesdb2025 🔬: Zebrafish, synchrotron micro-CT 🥼: chenglab.io 🥽: syGlass.io #DevBio #Zebrafish #syGlass #3DImaging #3DThursday