🎉 New for #3DThursday: #syGlass Learn is here! We’re bringing interactive anatomy curriculum to standalone VR headsets, with expert-guided lessons, immersive assessments, and a much easier way to deploy VR learning. Try it on the Meta Quest Store: www.meta.com/experiences/... #Anatomy #EdTech #VR

The #syGlass summer release is here for #3DThursday! ☀️ This update adds new ways to landmark, interact with, track, and explore complex 3D/4D data. Full post: www.syglass.io/blog/syglass... Huge thanks to Michael Barresi for the data used in the new splash screen! #VirtualReality #SciComm

🔬 For #3DThursday: a whole cleared mouse embryo imaged with DALISPIM from @lifecanvastech.bsky.social A theme from #FOM2026 + #ELMI2026 was that light microscopy innovation can come from rethinking imaging geometries, in this case an open-top inverted #lightsheet. 🎬: #syGlass v2.6.0

#MicroCT of a soybean bud complex for #3DThursday! 🌱 pollen-filled anthers arranged around the ovary that contains the ovules. 🔬 @zeiss-microscopy.bsky.social Xradia 520 Versa 🥼 @cygnusplantxray.bsky.social Keith Duncan 🏛️ @danforthcenter.bsky.social 🎬 #syGlass v2.6.0 #PlantScience #3DImaging

Mouse spine data #3DThursday from our partners at 3i! 🎉 Specimen from Pantelis Tsoulfas, imaged at #LSFM26 on 3i’s AxL light sheet. Axial sweeping helps preserve whole-spine context while improving optical sectioning across a thick cleared specimen. #syGlass @the.3i.social @univmiami.bsky.social

For #3DThursday, this is a 99-million-year-old earwig preserved in Burmese amber from the Sims Collection! 🔬: Miltenyi Biotec Blaze 🥼: Samuel Harrison 🪲: Jim Sims from Hamamatsu 🎬: #syGlass, v2.6.0 🏛️: #LSFM26, MDI @mdibl.org @hamamatsucorp.bsky.social @miltenyibiotec.bsky.social #scicomm #LSFM

🌌 Live painted sea urchin data for #3DThursday, ahead of #LSFM26 at MDI! 🔬: Bruker TruLive3D, light sheet microscopy, imaged over 12 hours in 1% agarose 🥼: Amro Hamdoun, from Tzer Han Tan's group at UC San Diego, data from Dane Maxfield 🎬: #syGlass, v2.6.0 @lsfm-na.bsky.social @mdibl.org #scicomm

📚 Good imaging comes from people being generous with what they know. Course season! #AQLM at MBL last week, #QFM in Bar Harbor next week, and I’ll be at #LSFM with a paddleboard + Sony screen. Here’s a light sheet medley of favorite 3D/4D datasets from this year! #syGlass #3DThursday

🥹 Still feeling grateful after #HarvardXR 2026, where syGlass won Best Emerging XR Startup and Best Applied XR Product. 🏆🏆 Thank you to the organizers and judges for a thoughtful, energizing event! #syGlass #HXR2026 #XR #AppliedXR #ScienceViz #3D www.syglass.io/blog/syglass...

For #3DThursday: a ~5 mm Parhyale hawaiensis female (with hatchlings!) imaged by #nanoCT. 🔍🦐 This tiny amphipod is a powerful #devbio model organism. 🥼 Neeharika Verma, Nipam Patel Lab 🔬 @zeiss-microscopy.bsky.social Versa 620 XRM 🏛️ @mblscience.bsky.social, UF Nanoscale Research Facility 🎬 #syGlass

🦎 A gorgeous Axolotl dataset for #3DThursday before I head to MBL for #NESDB2026. Those are tiny shrimps 🦐 in its stomach! 🔬: ZEISS Xradia 520 #microCT 🥼: Claudio Polisseni 🏛️: Max Planck Institute for Biological Intelligence @mpiforbi.bsky.social 🎬: #syGlass v2.6.0 @mblscience.bsky.social #Zeiss

🧠 Microscopy data are getting huge and increasingly hard to work with (this ex vivo human brain MRI dataset was ~8 TB!). In #syGlass, we use out-of-core octree rendering to stream only what you see, keeping VR interactive even at this scale. 🔬 7T MRI | 🏛️ MGH | BL Edlow et al #Microscopy #3DThursday

Ray casting for #3DThursday! 🔦 🦎 Veiled chameleon embryo, microCT 🥼 Raul Diaz 🎬 #syGlass v2.6.0 Direct volume rendering works on voxel data directly—casting a ray per pixel and combining signal along its path. Different models (MIP, average, absorption) highlight different structures + depth.

We won! 🏆🥹 syGlass took Best Emerging XR Startup + Best Applied XR Product at #HarvardXR this weekend. Best part (besides surviving the pitch 💀) was live demos on the #Sony Spatial Reality Display, including this #microCT of a chameleon embryo from R Diaz More soon 👀 #XR #3DVisualization #syGlass

#UMAP in VR for #3DThursday! In this zebrafish embryogenesis dataset, RNA-seq + ATAC-seq across 94k+ cells reveal changing regulatory programs over time. 🥼 Yang-Joon Kim, Loic Royer @loicaroyer.bsky.social , Matthias Haury 📝 www.biorxiv.org/content/10.1... 🏛️ Biohub @biohub.org 🎬 #syGlass v2.6.0

Happy #3DThursday from Sweden! 🇸🇪 This Thy-1 mouse brain was the crowd favorite at Focus on Microscopy this year 🐭 🔬: Zeiss Lightsheet Z.1 🥼: Chih-Wei Logan Hsu @cwloganhsu.bsky.social 🏛️: Baylor College of Medicine 🎬: syGlass, v2.6.0 #FOM2026 #syGlass #Microscopy @scilifelab.se

Fun #3DThursday update: #syGlass now supports the #Sony Spatial Reality Display! 🎉📺 Glasses-free 3D—no headset needed. Just walk up, look, and see depth instantly. A powerful new way to share scientific data with researchers, students, and the public. #3DVisualization #SciComm #EdTech

Super excited for this! I love his data ... join us on April 10th for the Spring Symposium: www.nesmicroscopy.org/2026-spring-...

☘️ A special #3DThursday for St Patrick's: Beer foam evolving in 4D in a microCT! 🍻 This is a Belgian Duvel (sorry not Irish...) from @tescan.bsky.social + Wesley De Boever Who’s off to #FOM2026 in Stockholm? I'll be there next week! www.focusonmicroscopy.org #Microscopy #MicroCT #Imaging #syGlass

Streaming OME-Zarr data directly into syGlass for #3DThursday🌍🔬 With #syGlass v2.6.0, datasets can stream from disk, S3, or HTTPS with no massive downloads required. Huge thanks to the community building open imaging standards: @openmicroscopy.org #OMEZarr #Microscopy #OpenScience #Bioimaging

The fruit fly of plant science for #3DThursday! 🌱 #ModelOrganism 🔬: #microCT, Zeiss @zeiss-microscopy.bsky.social Versa 520 XRM (contrast-enhanced with OsO₄) 🌱: Arabidopsis thaliana 🥼: Keith Duncan @cygnusplantxray.bsky.social 🏛️: Danforth Center @danforthcenter.bsky.social 🎬: syGlass.io #syGlass

📣 Announcing our #NESM Spring Symposium — April 10 (virtual & free!) We’re building an exciting lineup across the life & physical sciences. Interested in giving a talk? Submit your abstract by March 25 🗓️ Register: www.nesmicroscopy.org/2026-spring-... #Microscopy #Bioimaging

New in syGlass for #3DThursday: a VR surface brush for editing meshes🖌️Here, I’m isolating a component from a @lumafield.bsky.social #microCT scan of a VR headset, painting partitions directly onto the surface and exporting clean .OBJs: v2.6.0 #VR #3DVisualization #syGlass #ScientificVisualization

syGlass v2.6.0 is out for #3DThursday! ❄️ 🖥️ Sony Spatial Reality Display support ☁️ Direct OME-Zarr streaming from disk, S3, or HTTPS 🖌️ VR surface partition brush ⌨️ In-VR keyboard & numpad 🎮 Saved tool loadouts www.syglass.io/blog/syglass... #syGlass #Bioimaging #VR #3DData #OMEZarr #Sony

❤️ A cleared guinea pig heart for #3DThursday! Clearing a heart is HARD — dense muscle, deep antibody labeling, big volume. But to understand coronary networks, you need the whole organ. 🔬: Miltenyi Ultramiscroscope 🥼: Pam Rios Coronado, @pamrc.bsky.social 🏛️: Red-Horse lab @stanford.edu 🎬: #syGlass

Yes! Anyone doing microscopy in New England (or anywhere in the world!), we would love to feature your work. 🤗

🌕 Exploring a 3.6-billion-yo moon rock for #3DThursday! Showing how we can virtually slice through the volume, inspect internal structures, and take 3D measurements from #XCT data. 🔬: #Nikon XTH320 Scanner 🥼: Zoë Wilbur 🏛️: #NASA JSC Astromaterials X-ray Computed Tomography Lab 🎬: #syGlass, v2.5.0

Running TotalSegmentator inside #syGlass for #3DThursday! 🔬 Automated segmentation needs strong clinical data for training and benchmarking, plus models that generalize. Mayo Clinic Low Dose CT Grand Challenge + #TotalSegmentator by Jakob Wasserthal are great examples. #MedicalImaging #3DImaging

The Allen Mouse Brain Atlas is a cornerstone of #neuroscience: a standardized, high-resolution map of brain anatomy built to keep experiments comparable across labs. 🧠 Here’s a 3D walk through its anatomical meshes in #syGlass! @alleninstitute.org #3DThursday #DataViz #VR

For #3DThursday, a skeleton shrimp imaged on a Flamingo light sheet microscope — a modular, traveling #LSFM built to bring the microscope to the biology.🔬🦩Fast 3D imaging, low phototoxicity. 🥼: Carsten Wolff @carsten-wolff.bsky.social 📝: huiskenlab.com/flamingo/ 🏛️: @morgridgeinstitute.bsky.social

🪰 For #3DThursday, this #microCT scan of an adult #Drosphila (Schoborg et al.) captures the entire fly intact. Using #VR, we can teach anatomy by labeling the 3D fly from a 2D diagram. Spatial context changes everything. #SciComm 🔬: Bruker SkyScan 1172 🏛️: UWyoming 🎬: #syGlass, v2.5.0

2025 took us around the world 🌍 From Zurich to Beijing, London, Paris, Montreal, all over the Americas, we explored scientific datasets in VR with the researchers who created them -- and pushed #syGlass to new limits for 3D analysis. On to 2026. 🔬✨ #3DThursday #Microscopy #ScientificImaging

🎄 A canonical visualization dataset, revisited! This #CT Christmas tree (2001) became a classic for teaching & benchmarking volume rendering. I’ve brought it into #syGlass to explore how far #3Dvisualization has come — same data, new method. 🔬 #3DThursday Story: www.cg.tuwien.ac.at/page/xmas/

Nice feature from NVIDIA on #syGlass at the MBL! Exciting to see AI, RTX GPUs, and VR coming together to explore massive 3D brain datasets, with high school students contributing to ongoing, cutting-edge neuroscience research. @mblscience.bsky.social blogs.nvidia.com/blog/mbl-hum...

Label-free #holotomography for #3DThursday! This imaging technique lets you follow the same living organoid in 4D with no dyes or phototoxicity. 🔬: @tomocube.bsky.social, HT-X1 🧫: Mouse Intestinal #Organoid 🏛️: Institut Pasteur Workshop, Pushing the Frontiers of Dynamic Imaging 🎬: #syGlass, v2.5.0

#syGlass v2.5.0 is out! 🎉 New depth-aware colormaps, expanded file formats (NRRD/MRC/TCF/OME-Zarr v3), better #VR segmentation tools, and upgraded narration workflows — all focused on making #3Ddata easier to explore and share. Blog: www.syglass.io/blog/syglass... #Microscopy #Imaging #3DThursday

Guest lectured at UNH–Manchester’s Techniques in Microscopy this week, and the students are already thinking like researchers. Early exposure to real #Microscopy and #ImageAnalysis tools makes all the difference. 🔬: Zeiss LSM 510 🥼: Students + Prof Mark Scimone 🎬: syGlass.io #3DThursday #syGlass

One year of #3DThursday! Revisiting our first specimen, a Pekin duck: thanks to this community we learned she was Beaker, a rescued duck from Utah who later contributed to science. 🔬: #CTScan, Scarlet Imaging's BriteVu 🥼: Scott Echols 🎬: syGlass.io 🦆📸: credit TIFOtter #Anatomy #syGlass #SciComm

That's me! 🔬🥽😍

🫁Lungs for #3DThursday! Clearing + lightsheet lets you map airways, vasculature, and cell populations in their real spatial context. @miltenyibiotec.bsky.social 🔬: Miltenyi Blaze -- big, cleared, high-throughput 🏛️: Imaged at LSFM course at the MDI! @lsfm-na.bsky.social @mdibl.org 🎬: syGlass.io

Yes!!! 🎉

For #3DThursday we’re introducing Dynamic Depth color mapping! It encodes distance with smooth depth-aware gradients so layered structures pop without losing context. 🔬 #MicroCT of a P1 mouse 🥼 Hsu Lab, Baylor, @cwloganhsu.bsky.social 🎬 syGlass.io #Microscopy #SciComm #3DVisualization #syGlass

Taking over #3DThursday while Brandy Freitas @brandy-syglass.bsky.social is out of office for some adventures! 🦇: Rousettus aegyptiacus stained in 10% Lugol’s iodine for 3 months 🔬: PerkinElmer Quantum GX microCT 🥼: @acsharp.bsky.social 🏛️: University of Liverpool’s Centre for Preclinical Imaging

The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery. #Microscopy #Lightsheet #syGlass

It's #3DThursday, and we have the fan favorite dataset from the @bioimagingna.bsky.social conf in Montreal! Chaired by @minesbioimaging.bsky.social 🔬: 3i lattice #lightsheet 🥼: Nic Condon 🏛️: The University of Queensland 📝: doi: 10.1083/jcb.201804137 🎬: syGlass.io #syGlass #BINA #GBIxBINA2025

Had to check out a mummified snake in VR in front of a mummified man ... Took a detour from attending #BINA in Montreal to visit Natalie Reznikov at McGill University! @globalbioimaging.bsky.social @bioimagingna.bsky.social @mcgill.ca #MicroscopyMonday #syGlass #Microscopy #GBIxBINA2025 #McGill

💧 A male water flea (#Daphnia magna) for #3DThursday! Yellow 🟨 is musculature, magenta/gray 🟪 shows autofluorescence of its outer cuticle. 🔬: Fluorescence Microscopy 🥼: Carsten Wolff 🏛️: Marine Bio Lab @mblscience.bsky.social 🎬: syGlass.io #EnvironmentalScience #MBL #SciComm #Microscopy #syGlass

Reposting this spectacular octopus sent to our #NESM team from the @mblscience.bsky.social for #WorldOctopusDay!

🍺 It’s Oktoberfest, so let's look inside beer foam! Non-destructive imaging like this is key for food science and helps us understand how structure and stability affect things like aroma and taste. 🔬: TESCAN DynaTOM #microCT 🥼: Wesley De Boever 🎬: syGlass.io #Oktoberfest #3DThursday #Microscopy

👀 #3DThursday: Cross your eyes to see this super res pollen dataset in 3D! Good old fashioned stereo pairs in #syGlass bringing science to life. 🌿✨ 🔬: Zeiss LSM 980 with Airyscan 2 🥼: Nat Prunet, @nat-prunet.bsky.social 🏛️: UNC Biological Microscopy Core: tarheels.live/biologymicro... 🎬: syGlass.io