This time next year we will be wrapping up #ICTMC2026 in Birmingham. I'm already starting to think through ideas for abstracts. What trials methods research do you hope to hear about/present at the conference? ictmc.org

*New publication* Interventions to support patient decision making about taking part in health research: A systematic review doi.org/10.1016/j.pe... Just out in Patient Education & Counseling @sydneyhealthliteracylab.org.au @katiegillies.bsky.social

@anniestats.bsky.social gave a great talk on decentralised trials. Main message from PhD review work is there isn't a one size fits all approach. Trial design may need to be contextually determined and responsive to population needs #SCT2025

@liamhbishophealth.bsky.social kicks off his talk at #SCT2025 by thanking the Society for continuing to create space for raising EDI issues in clinical trials through recognition across sessions and committees. And gives a great talk on building trust through community focussed workshops and videos.

Using imp sci to consider how actionable regulatory guidance is for diversity in clinical trials. Rebecca Metcalfe highlights that more work is needed to make system-level changes to where and how trials are conducted. Building trusted relationships & enforcing guidance are key next steps #SCT2025

If you want more trials methods research post #SCT2025 please do come to #ICTMC2026 in Birmingham UK 14-17 September. More here ictmc.org

Adwoa Parker walking us through the update of the Cochrane review on interventions to improve recruitment. 7 years & >50 new studies doesn't tell us much more with high certainty. Suggests trialists think carefully about using interventions with no effect (bottom 3 in pic) #SCT2025

Founders Lecture #SCT2025 on DMCs - Thomas Fleming flags the @nihr.bsky.social funded DAMOCLES study that developed a charter for DMCs to support them to do their jobs well. Full paper here www.thelancet.com/journals/lan...

See how we can enable lower carbon clinical trials without compromising health outcomes. UCD, University of Liverpool, University of Galway, ICR, the HRB-TMRN, MRC-NIHR TMRP & PPI partners, co-developed this video about Greener Trials. www.youtube.com/watch?v=LbgG... #internationalclinicaltrialsday

From development to delivery, it takes a collaborative multidisciplinary team to make a clinical trial successful. Find out more about how Clinical Trials Units make research happen here: ukcrc-ctu.org.uk #ICTD2025 #ClinicalTrials #CTD2025

#ClinicalTrialsDay is the time to consider how to ensure the environmental sustainability of clinical trials. Read our @frankskyou.bsky.social write about why and how greener trials serve the purpose of benefiting the coming generations on SpringerNature blog: bit.ly/4moCL11

My highlight from #SCT2025 day 1 was Mollie Paynes talk on her PhD research on dose-response methodology in complex intervention trials. It's always great to hear a statistics talk that non-statisticians can also follow. Perfectly pitched. More on Mollies work here github.com/molliejpayne...

Tomorrow isn’t just International Clinical Trials Day. Keep your eyes peeled for the launch of our strategy for 2025 – 2030! #UKCTUNetwork #CTUNetworkStrategy

Late breaking session at #SCT2025 on the impact of recent US govt actions. So important for us to come together as a trials community to collectively support the research endeavour and our US colleagues. Flags an opinion piece in @nytimes.com today that encourages us to 'get mad in public'

There is a need for trials methodology research for trials designed & delivered in the global south. Sangeetha Paramasivan flags article on need for this work in RCTs in India & talks through adaptation of quintet recruitment intervention in this setting #SCT2025 www.thelancet.com/journals/lan...

Arun Sanyal giving the Curtis Meinert Keynote @ #SCT2025 talks us through the use of Desirability of Outcome Ranking (DOOR) in liver trials. Makes a suggestion for pan-specialty #CoreOutcomeSets to facilitate DOOR integration in evidence synthesis for intersecting clinical contexts.

One of our PhD students, Mojca Cerar, is running a survey to understand how recruitment & retention data in trials is communicated with trial sites. If you have any role in this process please complete our 10 min survey. We only have 23 responses with 2 weeks to go! forms.office.com/e/9RCxiiCXM2

NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social —> www.bmj.com/content/389/... #openscience #transparency #medsky #statssky #episky

Improving how we approach informing people about the potential risks and benefits of trial interventions. trialsjournal.biomedcentral.com/articles/10....

If you are doing work on equity, diversity and inclusion in randomised controlled trials, the journal Trials has a special series you could submit to: www.biomedcentral.com/collections/... Deadline end of June, and articles can be original research, commentary, education but not protocols.

Trial participant self‑reported understanding of randomisation phrases in participant info can be high but acceptability of some descriptions is low esp if linked to gambling/luck @streweek.bsky.social @katiegillies.bsky.social @taliaisaacs.bsky.social trialsjournal.biomedcentral.com/articles/10....

Currently low response rates from CTU Directors (n=5), Programmers/Data Managers (n=0), & QA Managers (n=3) working in clinical trials. We need to know what these groups think the challenges are for greener trials. forms.office.com/e/fkeLD8HbMA Please complete &RT @ukctunetwork.bsky.social

We now have 71 responses but need more if we are to identify the key challenges for the design and delivery of greener trials. Please complete and share onwards. Average completion time is only 12mins. We need to hear from you. forms.office.com/e/fkeLD8HbMA Thank you

Do you work on clinical trials? We need your help to understand the challenges to designing & delivering greener trials. Only 30 responses so far but we can all have a say on this topic. Please take 10 minutes to tell us what you think tinyurl.com/GreenTrials Please share across your networks

Great 1st paper from Frank You's PhD👏 Review headline-Much of the carbon in trials is associated with human behaviour. We found no studies investigating determinants of these behaviours. Soon to launch survey will help us fill this gap to make our trials greener. papers.ssrn.com/sol3/papers....

Long awaited legislation on clinical trials going before parliament today! www.gov.uk/government/n...

We are currently discussing the implications of trial post-randomisation exclusions at #CCRdownunder … the following paper by Dean Fergusson et al is a useful primer on when such exclusions might be acceptable and when they might not www.bmj.com/content/325/...

Funding available to do a PhD on statistical methods for assessing the integrity of RCTs, based in Aberdeen, with Alison Avenell, myself, Graeme MacLennan and Mark Bolland. Competitive process, funded by MRC Trials Methodology Research Partnership: www.findaphd.com/phds/project...

I’ve done a starter pack for people working in inclusivity in trial methodology but I can’t see some of the key people I’d like to include. Feel free to share @vickylshepherd.bsky.social @katiegillies.bsky.social @markjayes.bsky.social @kerryhood.bsky.social @willjcragg.bsky.social

A key component of trial conduct is monitoring of the integrity of the data quality and assessment that conduct of trial processes are being accurately followed 1/7 #MethodologyMonday #107

Great to read about others reflections on #ICTMC2024. Our ACE staff also shared their highlights from the conference here www.abdn.ac.uk/hsru/blog/ac...

Many of you know I post something about methods most Mondays on the “other side”… will share here too. Here is today’s … It is often important to assess not only the effectiveness of an interventions in a trial but also the #CostEffectiveness of the intervention 1/7 #MethodologyMonday #106

Collecting qualitative data remotely? New guidance published by the University of Warwick funded by UKRI, MRC, and NIHR publishing.warwick.ac.uk/index.php/uw...

Do you have a degree in a health related subject and experience of qualitative research methods?Are you looking for PhD opportunities? Would you like to work on trials methods research? Then this might be the answer.... tinyurl.com/DataIntegr

Characterising #machinelearning studies in healthcare, the full set Weak design/methods tinyurl.com/yc4easr9 Poor reporting tinyurl.com/55ed3j9k High risk of bias tinyurl.com/yk6m9sx5 Full of Spin tinyurl.com/yckubrnp Not open science tinyurl.com/437bfz8f #StatsSky #MLSky #mustdobetter 😬

I'm pretty new to Bluesky and haven't found all the trials methods researchers yet! Trying to bring us all together in one place for others to find & fill my feed with all things trials. Please feel free to share and let me know if you'd like added. go.bsky.app/AsP6Yta

Hello #Bluesky community ☺️ We are a community for #qualitative methodologists supported by the NIHR. Our aim is to raise awareness of the value & impact of qualitative methods in health & care research, provide opportunities for networking & career development. Pls follow & join our network🙂

What is Trials Methodology? Listen to Prof Paula Williamson tell us why its like making coffee....oh any why methods research on outcomes is important podcasts.apple.com/gb/podcast/t...

Presented the results of INITIAL at #ICTMC2024 - when should we consider patient involvement in stats analysis plans? Prioritised items focus on interpretation and dissemination of results & side effects. Crucial to make trials more relevant to patients bit.ly/3zVaITn

........dips toe in bluesky at the end of #ICTMC2024 to check what I missed out on over here