Join us for the #Ubiquitin & Friends Symposium 2026, April 29-30, in Vienna! Fantastic guest speakers👇 & many slots for talks from abstracts, flash-talks & posters. Lots of opportunities to network. Register now to save your spot! ➡️ www.protein-degradation.org/symposium/ #ubfriends2026

Molecular glue degraders don't just block proteins; they reprogram cellular recognition logic to eliminate "undruggable" targets entirely. Clues for Glues review by @zkozicka.bsky.social doi.org/10.1042/EBC2...

1 week to go! Würzburg's ready - are You? The GRK2243 Symposium 2025 is just around the corner. Pack your bags, prep your slides, and get hyped! #wUeBI2025

Excited to share our latest study on how K29/K48-branched #ubiquitin chains are forged by the #E3 ligase TRIP12, and how this suggests a consensus mechanism for chain formation by HECT E3s! @natsmb.nature.com 1/7 www.nature.com/articles/s41...

👏 Fantastic talk by Professor Craig Crews @craigmcrews.bsky.social at the Lund Spring Symposium on the past and future of PROTACs! 🎉 Congratulations on receiving The Special Achievement Award — well-deserved recognition for major contributions to TPD! #TPD #PROTAC #LundSpringSymposium

🗺️ Interactive Map Update! 2 new UK-based labs have been added to the global TPD map: 🔹 Kessler Lab @kesslerbenedikt001.bsky.social 🔹 Fletcher Lab Explore these and many other TPD and ubiquitin labs: 👉 tpd-community.com #TPD #ProteinDegradation #Ubiquitin

🗺️ Interactive Map Update! The Münch Lab @cmunch.bsky.social has joined the global TPD map! 🎉 Explore their work and discover other labs studying #TPD and #ubiquitin biology. 👉 tpd-community.com #ProteinDegradation

🗺️ Interactive Map Update! The map was just updated with 3 more labs from Germany working on TPD: 🔹 Hausch Lab 🔹 Knapp Lab 🔹 Gersch Lab @maltegersch.bsky.social Explore these and other labs advancing TPD and ubiquitin biology: 👉 tpd-community.com #TPD #ProteinDegradation #Ubiquitin

Great to see this out. A story that spanned continents, cities and budget codes… www.nature.com/articles/s41... Big thanks to all the teams involved! @clausenlab.bsky.social @e3chembio.bsky.social

🔬 Lab Spotlight: Malte Gersch Lab at Max Planck & TU Dortmund @maltegersch.bsky.social Recent paper: New insights into DUB inhibition & crystallization! 👉 www.nature.com/articles/s41...

🧬 Exploring degraders? Check out PROTAC-DB — a free, searchable resource with data on 3,200+ PROTACs, warheads, linkers, E3 ligands, and more. Includes binding data, degradation metrics, ternary structures, and WB images. 🔗 Dive in: cadd.zju.edu.cn/protacdb/ #PROTAC #TPD #DrugDiscovery

Day 1 one #ubfriends2025 was full of great 🎤talks, creative elevator pitches, lively poster sessions and stimulating discussions...

🗺️ TPD Research Map Update! 5 new labs just joined the global TPD map: 🔹 Slabicki Lab 🔹 Kaneko Lab 🔹 Wiener Lab 🔹 Korenblit Lab 🔹 Zhuang Lab Explore these and many other labs working on targeted protein degradation and ubiquitin biology! 👉 tpd-community.com #TPD #ProteinDegradation #Ubiquitin

📢 Next week at the DFCI TPD Seminar (May 15, 12PM EST): 🎙️ Talks by Rebecca Metivier and Martin Steger on using mass spec proteomics to uncover degrader targets. Don’t miss it! #TPD #Proteomics #Degraders

PVDF vs Nitrocellulose? How to Choose a Blot Membrane 🤔 If you're optimizing your blots, this guide from Fisher Scientific breaks down when and why membrane matters: 📌 Also includes practical tips for handling and troubleshooting. #WesternBlot #LifeScienceTips

🔬 New from the Itay Koren lab: 💥 TOM20 anchors an E3 ligase to drive UPS-dependent control of mitochondrial fusion/fission via PLD6 degradation. doi.org/10.1038/s415... 👏 Congrats to all authors! 📍 Find the Koren lab + others on our map: tpd-community.com #Ubiquitin #ProteinDegradation

🚨 Next week! The Ubiquitin & Friends Symposium 2025 in Vienna 🇦🇹, May 8–9! Great science, great people, and great event for anyone into ubiquitin & TPD. 🔗 www.protein-degradation.org/symposium/ 👥 Organizers: @sfb-tpd-vienna.bsky.social #TPD #Ubiquitin #ProteinDegradation

🔬 GRK2243 Symposium – Understanding Ubiquitylation 📅 June 2–4, 2025 📍 Würzburg, Germany A 3-day deep dive into ubiquitin biology—from molecular mechanisms to disease and therapeutic strategies. 👥 Hosted by @GRK2243 🔗 Full info: www.ubiquitin-wuerzburg-2025.de #TPD #Ubiquitin #wUeBI2025

🧬 Want to see who’s working on Targeted Protein Degradation or ubiquitin biology? 🔍 Explore our interactive map of research labs worldwide: 🌐 tpd-community.com#the-map Discover labs and find collaborators. #TPD #Ubiquitin #ProteinDegradation #ResearchMap

Welcome to the hub of Targeted Protein Degradation (TPD) and ubiquitin biology. 👋 Connecting the global TPD & ubiquitin biology community. 🔬 Find labs, discover events, and stay in the loop. 🌐 tpd-community.com #TPD #Ubiquitin #ProteinDegradation