Just got the news that Vanessa Ruta, Steve Liberles, and Uli Mueller are all elected to be members of the National Academy of Sciences @nasonline.org. All 3 are incredibly well-deserved. Congrats to all the new members! 🎉

My quote of the day Space isn't remote at all. It's only an hour's drive away … if your car could go straight upwards. Fred Hoyle

Congratulations to David Ginty and Patrik Ernfors for receiving The Brain Prize! 🎉👏 You can help David celebrate at this conference: www.janelia.org/you-janelia/...

Very excited to share our new manuscript – published today! Why are PIEZO1 and PIEZO2 are tuned to transduce different types of mechanical force? I was lucky to work with some extraordinary colleagues to begin to figure out why. www.nature.com/articles/s41... An overview of the results below ⬇️ ⬇️

So proud of my lab mate @ericmulhall.bsky.social and honored to help with this amazing project he led using MINFLUX to study why PIEZO2 behaves differently than PIEZO1 from the lab of @ardemp.bskyverified.social share.google/2Uln5O5OyqhM...

This is the SAVE Act that Trump is discussing tonight.

Rita Levi-Montalcini was raised by a strict father who disapproved of women in higher ed. She convinced him to let her study medicine. She went on to co-discover the Nerve Growth Factor. She received the Nobel Prize in 1986. She was another immigrant that gifted the US with pioneering work. 🧪

I’ve never met anyone that would be better for this job. We need more scientists in congress!

Excited to co-host this conference with @marissascavuzzo.bsky.social and Steve Liberles focused on the peripheral nervous system -- No Brainer! Check out the amazing list of speakers and apply for one of the spots for this small, interactive meeting on the beautiful Janelia Campus at HHMI.

News from central Jersey: I'm running to represent New Jersey's 12th Congressional District. By entering the fray, I hope to bring ideas of repairing our frayed republic. Not only to defend it in 2026, but to build something stronger, for generations to come! samwang.substack.com/p/entering-t...

The appropriations bill that includes NIH is being finalized. The Senate bill includes a bipartisan amendment from Senators Capito (WV) and Baldwin (WI) limiting multi-year funding of grants. The House version does not and OMB has issued a veto threat if the House includes such language. 1/3

HEY WAKE UP. www.theguardian.com/us-news/2026...

Of the hundreds of millions of people living with IBS worldwide, about two-thirds are women. Now, researchers have identified a biological pathway in the guts of mice that may help explain this disproportionate toll—a finding that could one day lead to new treatments. https://scim.ag/3YD8H78

When overwhelmed by scope of tragedy, specifics can be important. Here is just one story. Thinking of all those affected by this weekend's tragedies at Brown and in Sydney.

Axolotls are famous for regenerating limbs. Turns out they can also regenerate their thymus—and that may show us how to someday to the same. That story and more of the best from @science.org and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪

Congratulations! Check it out - very cool work! (and beautiful image!).

Great story by @carlzimmer.com in @nytimes.com that nicely conveys the excitement for the emerging field of interoception. @dulaclab.bsky.social and others are featured, including my tattoo 😳! Gift article link: www.nytimes.com/2025/11/25/s...

Application review launches on December 1, 2025. We want to read *your* application outlining a vision for a research program deciphering how membrane proteins collaborate to enable cell function, their biosynthesis, and the biophysics and structure of how membrane proteins change shape.

Good morning everyone! So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory* www.amazon.com/How-Change-M...

Bhattacharya's newest 1-page pandemic plan forcefully rejects the GBD, his previous 1-page pandemic plan. It's really just an admission that he's not competent enough to control a virus and not caring enough to even try. My latest devastating takedown. sciencebasedmedicine.org/bhattacharya...

Re-upping this - Neuropeeps! We have a TT Job in my wonderful department at Brandeis! First consideration to applications received by Dec 15 (but why wait?) www.nature.com/naturecareer...

Our preprint is out! www.biorxiv.org/content/10.1... Peter Skovorodnikov and I are excited to present FERAL: a new video-understanding toolkit that maps raw video directly to behavior, no pose estimation required. It works across species, from lab to field, and even in collective systems. (🧵1/n)

"Even Nobel Prize Winners Deal With Imposter Syndrome": Check this out @scifri.bsky.social: www.sciencefriday.com/segments/ard...

Dr. Florence Sabin | Immunologist and educator, born #OTD in 1871. The first woman to hold a full professorship at Johns Hopkins School of Medicine (where she graduated from in 1900) and the first woman elected to the National Academy of Sciences. #WomenInSTEM

When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #STEMSTEAMDay: https://scim.ag/4qFrPON

Excited to share our latest @nature.com: How does naloxone (Narcan) stop an opioid overdose? We determined the first GDP-bound μ-opioid receptor–G protein structures and found naloxone traps a novel "latent” state, preventing GDP release and G protein activation.💊🧪 🧵👇 www.nature.com/articles/s41...

The United States was the leading destination for top scientists from all over the world. That is ending. Politicians ended it. It will cripple our future competitiveness. And it’s such a bitter tragedy. Almost no Americans, Conservative or Liberal, grasp what is now being stolen from them.

Excited to report the identification of small molecule inhibitors of OTOP1 and their binding sites. Congratulations to first authors Batuuji Burendei from Ward/Forli labs at TSRI and Josh Kaplan for great team work! rdcu.be/eMpV9

Maud Menten was born in Canada in 1879 and completed her UG and MD education at University of Toronto. As a research assistant with Leonor Michaelis in 1912, they wrote the classic paper describing the “Michaelis-Menten” model of enzyme kinetics.. #WomenInScience

During these uncertain times, I’m very happy to see that my institution, @scripps.edu has an open tenure-track Assistant Professor position. Any field in Chemistry or Biology is welcome. I’d especially love to see fellow neuroscientists apply. Please repost! apply.interfolio.com/174756

My quote of the day Nancy Hopkins et al., A Study on the Status of Women Faculty in Science at MIT (1999)

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! 🧪 jobs.rutgers.edu/postings/260...

“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.” ― Jane Goodall 💙 RIP to a real one. My childhood hero

Here's a reminder on #InternationalCoffeeDay: It's OK to take a (coffee) break. ☕ "It’s ... helpful to have a venue to share the day-to-day ups and downs of life as a grad student," a #PhD student wrote in this 2019 #ScienceWorkingLife. https://scim.ag/4nvLTBb

More guns than people… Is it freedom or a national death cult that keeps growing?

Students/Postdocs - a great opportunity to work with an incredible scientist, and wonderful mentor!

Our 6-hands review/perspective: "Hacking 3D printers as laboratory robots" is now on ChemRxiv. In there, we show how many robots you can make by simply modifying a 3D printer. #chemsky 1/n with @sandersays.bsky.social and @supersciencegrl.co.uk chemrxiv.org/engage/chemr...

I have to take this Research Security training to be eligible to submit Federal grants and as I'm going through it the contrast between what is being presented and how the current Federal administration is acting is enraging

Please share with anyone who cares about NSF support for graduate students and take 30 seconds to sign and leave a comment. The deadline for the 2025 Graduate Research Fellowship Program is about one month away and literally no one can apply. #NSFGRFP jasonjwilliamsny.github.io/grfp2025/

This is huge: “A drug that provides near-perfect protection against H.I.V. with shots just twice a year will be made available at $40 per patient annually in low- and middle-income countries, offering new hope… making lenacapavir a realistic choice in countries with constrained resources.”

New cures feel sudden, but the seeds were planted decades ago by basic scientists. Which seeds will turn into cures? Unpredictable looking forward, a straight line looking back. 🧪🧬 🧵

Cecilia Payne-Gaposchkin ✨ figured out what stars are made of ✨ when she was just 25. 🔭🧪 Her PhD thesis basically established the Harvard astro department — at a time when Harvard didn't officially allow woman students. I wrote this little profile to mark the 100th anniversary of her thesis:

Ed Kravitz passed away yesterday. He was a remarkable scientist and mentor- brilliant, curious, creative, and kind. I am grateful to have learned from him. His legacy will endure through his science and through the many people he inspired. We will miss you, Ed.

A true honor to perform “American Tune” with #PaulSimon and the incredibly talented students at Juilliard. As I said in the article, I remember first looking at the lyrics of “American Tune” and going “Oh, my God — did you write this yesterday?”

Translational ion channel research at its best. The 2025 Lasker~DeBakey Clinical Medical Research Award goes to Michael Welsh, Tito González, and Paul Negulescu for their role in developing a novel drug treatment for cystic fibrosis.

This rule would have meant I couldn't do my Ph.D. in America. I did do it in America. Became a professor. 12 thriving U.S. labs are now headed by trainees from my research lab. Like me, they are all working hard to enrich American knowledge and society. With this self-harming rule, none of that.

"Pediatric Brain Cancer Trial Group to Be Phased Out" "A network of hospitals and cancer centers dedicated to early phase trials of novel treatments will no longer receive federal funding." 🎁🔗 Nina Agrawal for @nytimes.com

Very excited to share our most recent work on using de novo design to custom engineer a small peptide that can restore proper sodium channel function in disease … to be able to “write” proteins to do whatever we want them to do, is just remarkable …