In our latest paper, we show that inducible sk. muscle AXIN1 /2 double KO have normal AMPK, mTOR and glucose uptake regulation, questioning previously proposed dependencies on this scaffold protein. Thanks to all co-authors for their contributions physoc.onlinelibrary.wiley.com/doi/10.1113/...

Latest from Jonas Treebak and team @cbmr.science NAD depletion in skeletal muscle does not compromise muscle function o... www.sciencedirect.com/science/arti...

Check out our latest paper challenging the long-standing belief that insulin elicits a transient H₂O₂ production. New insights into skeletal muscle redox signaling and insulin action 🤩

Our new paper in Redox Biol showing that insulin stimulation of skeletal muscle surprisingly does not detectably increase the ROS H2O2 using state-of-art methods in different models including humans, but in fact causes a selective reductive shift - enjoy www.sciencedirect.com/science/arti...

“Exploring NADPH oxidases 2 and 4 in cardiac and skeletal muscle adaptations – A cross-tissue comparison” by @robertoandresmv.bsky.social, @musclebiology.bsky.social, @elbenhardt.bsky.social et al. (sorry if I do not find all of the #bluesky handles). www.sciencedirect.com/science/arti... 3/17

🚨Paper Alert 🚨: PanK4 Identified as Regulator of Glucose and Lipid #Metabolism. A new study led by mkleinert.bsky.social‬ at our DZD-Partne#DIfEfE has identified PanK4 as a key regulator of energy metabolism in skeletal muscle. ⬇️ ⬇️ ⬇️ ⬇️

Our new FASEBJ paper. We looked into mTOR Ser1261 phosphorylation in human and mouse muscle, proposed by Diane Fingar's lab to be first an Akt and then AMPK site regulating mTORC1 and 2 activity. Clearly AMPK site but impact on mTORC unclear in our hands faseb.onlinelibrary.wiley.com/doi/10.1096/...

Curious about muscle metabolism? 🚴‍♂️ We reveal PanK4 as a conserved exercise target in muscle! 💪 PanK4 regulates lipid & glucose use likely via acetyl-CoA. We think PanK4 belongs alongside Akt, mTOR, AMPK, Rac1 & more as a key player in muscle energy homeostasis. #Metabolism #MyoBlue

Pantothenate kinase 4 controls skeletal muscle substrate metabolism www.nature.com/articles/s41...

A new biosensor is born 👼 The NAPstar family of genetically-encoded sensors for live NADP redox monitoring🔋🪫 Jointly with the Morgan lab & @riemerlab.bsky.social we looked in vitro, in yeast, plants & mammalian cells 🧪🦠🧫🌱 Where to go next? @naturecomms.bsky.social doi.org/10.1038/s414...

🌟 ICYMI: Altmetric now tracks Bluesky mentions! ✔️ Comprehensive social media coverage 📊 Mentions reflected in your Altmetric score 🌐 Stay ahead in tracking research discussions Your research is moving to new spaces—don’t miss a thing! Read more here: www.altmetric.com/bl... #AcademicSky

New from Anna Krook and team. Biological sex differences in skeletal muscle metabolism and exercise adaptation in People with type 2 diabetes #myoblue #exercise #metabolism www.nature.com/articles/s41...

Let’s try out this new platform by sharing our recent paper on the transcriptional signatures of individual muscle fibers following high-intensity exercise #myoblue #myosky journals.physiology.org/doi/abs/10.1...

Neither the conference organisers nor the artist are (yet) on here but look at this amazing live drawn summary of my #MetabolismInAction paper by Eleonora Nigro #HistSTM #PolarHistory