Preprint: In PD-L1-gain EBV+ DLBCL, T cells get close to tumour cells but rarely touch them; a spatial "decoupling" of proximity and engagement. Fibroblast barriers, metabolic suppression, and T cell exhaustion together block anti-tumour immunity. 🧵1/5 doi.org/10.64898/202...

Really nice interactive here. Also, tax these killing machines into obscurity. www.nytimes.com/interactive/...

🧬 EaCoN v0.5.0 "Parallel Universe" is out! A modernized fork of Bastien Job's (@gustaveroussy.fr) copy number analysis package for Affymetrix arrays: → foreach/doParallel fully replaced with furrr/future + purrr/dplyr → R ≥ 4.2.0 compatible → OncoScan, CytoScan, SNP6 github.com/kunstner/EaCoN

Now published: journals.plos.org/plosbiology/...

🦁 New preprint! We developed LION — a manufacturer-independent, 109-gene liquid biopsy panel for pan-cancer ctDNA analysis to support clinical decision-making. 📄 Preprint on medRxiv: www.medrxiv.org/content/10.6... #LiquidBiopsy #ctDNA #CancerGenomics #NGS #Oncology #Bioinformatics

🧠 New paper out in Cancers! We profiled 49 solid tumor brain metastases and found that the adenosine pathway (CD39/CD73) is a frequent immune escape mechanism - often operating independently of PD-L1. #BrainMetastases #CancerGenomics #Oncology #OpenAccess www.mdpi.com/2072-6694/18...

🧬 New paper out in @Cancers_MDPI! We show that Regnase-1 is a prognostic biomarker in high-grade soft tissue sarcoma — favorable in UPS, but flipped in adjuvantly irradiated patients. Context matters! 👉 www.mdpi.com/2072-6694/18... #SarcomaResearch #CancerBiomarkers #Immunology

Preprint alert! 🚨 www.preprints.org/manuscript/2... High-grade soft tissue sarcomas (STS) lack robust biomarkers—but we may have a new signal. #Sarcoma #Immunology #CancerResearch #TumorMicroenvironment #Biomarkers #Oncology

Fresh from the press www.nature.com/articles/s41...

Some news from the press www.nature.com/articles/s41...

Fresh from the press with some minor contribution from our group onlinelibrary.wiley.com/doi/10.1111/...

📢 Just out: Our study reveals the molecular secrets of primary renal DLBCL (prDLBCL) @bloodadvances.bsky.social #DLBCL #Lymphoma #Genomics 🧵 ashpublications.org/bloodadvance...

📢 New Research Alert: #Lymphoma #Genomics #RenalMZL @bloodadvances.bsky.social Primary renal marginal zone lymphoma (prMZL) is extremely rare (and often misdiagnosed). We published the largest molecular study to date on this entity. 🔗 ashpublications.org/bloodadvance... Main findings 🧵👇

PICRUSt2 received an updated database academic.oup.com/bioinformati...

Another one this week with contribution of our working group elifesciences.org/articles/98970 @uniluebeck.bsky.social

Fresh from the press: www.embopress.org/doi/full/10.... #microbiome

Today's #Microbiome digest microbiomedigest.com/2025/04/06/a... @elisabethbik.bsky.social #microbiomesky 🦠

New to data science with #RStats or need a refresher? I always recommend R for Data Science (r4ds.hadley.nz) – a free online book by @hadley.nz that takes you from importing data to statistical modeling in a gentle, beginner-friendly way. #datascience #rladies #r4ds

Schaut sich niemand die Bildunterschriften noch mal an? @tagesschau.bsky.social

6 days left to apply to the Post-doc opening in our lab @ebi.embl.org to develop&apply #bioinformatics & #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data: embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

Are you a bioinformatician looking for an exciting opportunity in Melbourne? Is cancer genomics your passion? Apply now! www.nature.com/naturecareer...

🧬 Just published in Annals of Hematology! Thanks to the H. Witte, N. Gebauer, T. Hahn and others for pushing this study forward. link.springer.com/article/10.1... #HodgkinLymphoma #CancerGenomics #HematologyResearch #LymphomaGenetics #PrecisionOncology

I don't know how many Swedish speaking contacts I reach here, but if anyone is interested in wolfs and conservation genomics, I'll give a popular science evening lecture about it next Thursday! That is European evening time. In Swedish..🇸🇪 www.studieframjandet.se/uppsala-lan/...

Beyond prostate cancer: Androgen receptor signaling plays a key role in multiple malignancies. Dotto & collegues explore AR’s context-dependent functions in cancer cells & the TME, and highlight AR-targeting cancer trials. 📖 👇

📢 We’re looking for a new Team Leader! @enasequence.bsky.social is recruiting a Team Leader to shape the strategy and direction for the ENA and Biosamples open data resources. Interested?👇

Do you love software engineering for exciting biological applications, open science,open source, R, Bioconductor, modern web, cloud& ML technologies? We're looking for a software engineer to work on R/Bioconductor tools for biological data science and AI embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

I joined the Microbiome Digest team in 2018 (thanks to @elisabethbik.bsky.social) and what a journey it's been! Learned so much about microbiome science and connected with amazing researchers along the way. Looking to contribute? Come join our community!

My new book ‘The Cancer Roadmap’ was launched today It’s for anyone affected by cancer It tells you what is it, what causes it, how it’s treated, who to trust, how to understand risk + spot red flags on social media when it comes to alternative cures. Get yours here lnk.to/TheCancerRoa...

#NeverAgain #NeverAgainNeverForget #NeverAgainIsNow

R.I.P. David Lynch

A paper in Nature presents an AI model that can translate speech and text, including direct speech-to-speech translations, for up to 101 languages. The model, named SEAMLESSM4T, fills gaps in language coverage and outperforms existing systems. 🧪

Final call for our #postdoc recruitment on #gut #microbiome, deadline in a week! Please share!🦋 #MicroSky #AcademicSky #GISky #PhDSky

At Stockholm University, we are now starting a 2-year Master’s programme in Evolutionary Genomics! Topics include population genetics, phylogenetics, molecular & genome evolution, DNA sequencing, bioinformatics, and palaeogenetics. Please spread the word! www.su.se/english/sear...

The Finish publication forum downgrades almost all MDPI and Frontiers Journals to 0 from the beginning of 2025. These Journals are not considered as properly peer reviewed trustworthy scientific journals. julkaisufoorumi.fi/en/news/chan...

Hi Bluesky community! 👋 Are you looking forward to 2025 as much as we are? 👀 We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look! ➡️ s.embl.org/poster-bl #EMBLEvents #molecularbiology #lifesciencetraining

🧬 Are you a #bioinformatician with some Swedish skills & interest in #microbiology looking for a job in #genomics ? 🦠 Come work with Sofia, Lili, me & co at Clinical #Microbiology at Karolinska Uni Hospital in Stockholm! Flexible role and great people! regionstockholm.varbi.com/what:job/job...

Today's #Microbiome digest microbiomedigest.com/2024/12/09/d... @elisabethbik.bsky.social #MicrobiomeSky 🦠

Looking for a #postdoc in #hematology in combination with #epigenomics, #metabolism and biochemistry? 👉Have a look at this opportunity in my lab. www.dkfz.de/en/postdoc-p... #HemeSky

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...

PhD opportunity in computational population genetics at @MPI_EVA_Leipzig: Join our fully funded project to develop IBD-segment tools, connecting high-quality genomes from 500 Black Death victims to modern Europeans. 🌍💻🧬 Please spread the word! 📢🙌 #aDNA #PopGen www.eva.mpg.de/de/karriere/...

#Bioinformatics in clinical practice from the Nordics. Highly recommended to read! www.biorxiv.org/content/10.1...

4-year funded PhD: Urban green space as refuge for people and disease vectors under climate change: a double-edged sword Very interdisciplinary (topic, approach, team): vector ecology, human behaviour; mapping and modelling! www.findaphd.com/phds/project... Application deadline: 6 Jan 2025 (1/2)

Current members: Juan Pablo Cardenas @knstnr.bsky.social @dna-heligrace.bsky.social @svetlanaup.bsky.social @elisabethbik.bsky.social Feel free to join us. Just DM me.

Our friends at EMBL Australia have called for expressions of interest for the position of Scientific Head. It's a fantastic opportunity for senior scientists based in Aus to bring a vision, stakeholders, and resources to a network that has produced such vibrant scientists and discoveries. 🧪

Just recently published in @Nutrients_MDPI with some minor contribution from the Busch lab www.mdpi.com/2072-6643/16...

Fresh from the press with some minor contribution from us www.frontiersin.org/journals/pha...

Got a PhD in bioinformatics or quantiative/CS degree? Want to work with AI on real world health care data, using some of the biggest and most complete datasets in the world? Want to live in Cambridge UK and work in European EMBL? This job in my research group is for you! www.embl.org/jobs/positio...

There is still time to apply! Associate professor, immunity/inflammation/infection (defined broadly) especially welcome Come and join a great community of supportive colleagues! Deadline 25 October, please spread the word www.path.ox.ac.uk/vacancy/asso...

Today's #microbiome digest microbiomedigest.com/2024/10/10/o... @elisabethbik.bsky.social #MicrobiomeSky 🦠