In a pre-planned exploratory analysis of the DOTS RCT, achieving a total day-22 dalbavancin concentration >32 µg/mL was associated with higher rates of clinical success in patients with complicated Staphylococcus aureus bacteremia. #ESCMIDGlobal2026 ja.ma/4e0SOAx

Among adults with #AcuteSinusitis, standard-dose amoxicillin-clavulanate did not reduce treatment failure compared with amoxicillin, while overall failure and hospitalization rates were low in both groups. #ESCMIDGlobal2026 @escmid.bsky.social ja.ma/4mD2ymI

Lipid-based amphotericin B formulations (ABCD/L-AmB) were associated with better outcomes than deoxycholate (AmB-d) in non-HIV-associated cryptococcal meningitis: A retrospective cohort study Junyu Liu and others Medical Mycology, myag033, doi.org/10.1093/mmy/...

Phase I studies assessing safety and pharmacokinetics of nacubactam administered alone or in combination with cefepime or aztreonam in Japanese healthy participants Jun Morita, et al. Antimicrobial Agents and Chemotherapy, 2026 doi.org/10.1128/aac....

Detection to Disruption: A Comprehensive Review of Bacterial Biofilms and Therapeutic Advances Pranay Amruth Maroju et al. Antibiotics 2026, 15(4), 396; doi.org/10.3390/anti...

The Upcoming Antifungal Drugs in Clinical Development for the Treatment of Invasive Candidiasis Zubovskaia A, Vazquez JA Infection and Drug Resistance 2026:19 547511 doi.org/10.2147/IDR....

New in @science.org ‼️ In the most comprehensive study to date, we show that wildlife trade is driving animal-to-human zoonotic spillover at a planetary scale, with +1 spillover per host every 10 years. Live animal markets and illegal trade pose even greater risks. 🔓 www.science.org/doi/10.1126/...

GOOD NEWS! Researchers at Stanford University have developed a UNIVERSAL vaccine known as GLA-3M-052-LS+OVA, that protects against a wide range of respiratory viruses, bacteria AND even allergens. The vaccine is delivered intranasally AND provides broad protection in the lungs for several MONTHS.

Antibacterial prophylaxis and antimicrobial stewardship in the era of innovative therapies for haematological malignancies: transplantation, cellular therapies and new drugs R Dell’Acqua and others JAC-Antimicrobial Resistance, April 2026, doi.org/10.1093/jaca...

A first-in-human phase 1 clinical study in healthy volunteers to assess the safety, tolerability and pharmacokinetics of EDI048, a novel promising agent to treat enteric cryptosporidiosis Monish Jain and others The Journal of Infectious Diseases, jiag210, doi.org/10.1093/infd...

Review: Exploring coronavirus cell entry with functional viromics journals.asm.org/doi/10.1128/...

Out Now! A penicillin-binding protein inhibitor series to target drug-resistant Neisseria gonorrhoeae #MicroSky

Current status of immunomodulatory therapies in adult sepsis patients: where do we stand? Dimitra Papatheodosiou, et al. Review of Anti-infective Therapy, 2026. doi.org/10.1080/1478...

We're pleased to announce our 2026 guideline update to induction treatment for cryptococcal meningitis! sahivsoc.org/Files/SAHCS%... @neleshg.bsky.social @tomboylesid.bsky.social #HIV #CryptococcalMeningitis

Safety, tolerability, and immunogenicity of a 31-valent pneumococcal conjugate vaccine (VAX-31) in healthy adults aged 50 years and older from the USA - phase 1/2 clinical trial James Wassil, et al. Lancet Infectious Diseases, 2026. www.thelancet.com/journals/lan...

Comparison of ceftolozane-tazobactam and ceftazidime-avibactam in the treatment of MDR/DTR Pseudomonas aeruginosa infections: a systematic review and meta-analysis Milo Gatti , Riccardo De Paola , Beatrice Giorgi , Federico Pea Clinical Infectious Diseases, ciag194, doi.org/10.1093/cid/...

www.eurekalert.org/news-release... Jesus, this is really Eureka!! You guys eventually understand this mega obvious thing! 😂😂😂

Our new @plos.org Pathogens Pearl asks a simple but important question: When Candida is detected in the respiratory tract, what does it actually mean? TLDR Answer: caution, context, and much better diagnostics! @mrccmm.bsky.social @nihrexeterbrc.bsky.social dx.plos.org/10.1371/jour...

Wow wow! How this could be?? )) Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19. Glascock A., et al. Nat Microbiol, 2026. doi.org/10.1038/s415...

Short Antibiotic Treatment for Coagulase-negative Staphylococcal Sepsis in Premature Infants: A Multicenter Noninferiority Study d’Haens, Esther J. et al. The Pediatric Infectious Disease Journal 2026. DOI: 10.1097/INF.0000000000005209

Current status of immunomodulatory therapies in adult sepsis patients: where do we stand? Dimitra Papatheodosiou, et al. Expert Review of Anti-infective Therapy, 2026 doi.org/10.1080/1478...

Timely antibiotics and fluid resuscitation are associated with increased discharge to home after sepsis Hallie C. Prescott, et al. CHEST, 2026 journal.chestnet.org/article/S001...

Clinical data, chest X-ray or C-reactive protein to initiate antibiotic therapy in outpatients with suspected community-acquired pneumonia: a prospective, randomised, controlled, digital case vignette study Juliette Pinot, et al. CMI, 2026 www.clinicalmicrobiologyandinfection.org/article/S119...

Synergistic activity of caspofungin and posaconazole against Candida (Candidozyma) auris biofilms based on phenotypic, transcriptomic, and in vivo insights Microbiology Spectrum, 2026. Fruzsina Kovács, et al. doi.org/10.1128/spec...

Human serum albumin and biological fluids reduce cefiderocol activity in carbapenem-resistant Gram-negative bacteria Azadeh Varnado, et al. International Journal of Antimicrobial Agents, 2026. doi.org/10.1016/j.ij...

Antimicrobial therapy for infected necrotizing pancreatitis: microbiology, antimicrobial resistance and pharmacokinetics Hannah S. Pauw et al. J Antimicrob Chemother 2026; 81: dkag092 doi.org/10.1093/jac/...

Sterilization and High-level Disinfection in 2026: New and Emerging Topics Emily Sickbert-Bennett et al. Infectious Disease Clinics of North America Available online 10 March 2026 doi.org/10.1016/j.id...

mGem: Fungal adhesins in Candidozyma auris confer unique fitness for skin colonization Abishek Balakumar, Shankar Thangamani mBio 2026 doi.org/10.1128/mbio...

Vinay Prasad, key Makary ally and a focus of controversy at the FDA, is leaving the agency 😀 www.statnews.com/2026/03/06/f...

How to safely discontinue antifungal treatment in invasive pulmonary aspergillosis? – Clinical considerations in haematology Jannik Stemler et al. Clinical Microbiology and Infection, 2026 www.clinicalmicrobiologyandinfection.org/article/S119...

Global, regional, and national burden of Clostridioides difficile infection (1990–2021) with projections to 2051: A multimodal analysis integrating machine learning (SHAP-XGBoost) and GBD 2021 data. Zhao W., et al. Eur J Clin Microbiol Infect Dis 2026 doi.org/10.1007/s100...

Pfizer CEO Albert Bourla on FDA official Vinay Prasad: 'We have a problem with the leadership of CBER' www.fiercepharma.com/pharma/pfize...

Pfizer CEO Albert Bourla on FDA official Vinay Prasad: 'We have a problem with the leadership of CBER' www.fiercepharma.com/pharma/pfize...

Stanley Plotkin had a major hand in the development of a number of vaccines in use today; he designed the rubella vaccine. He remembers the world before widespread use of vaccines & knows what's coming as vaccine policy is rewritten & vaccine confidence is eroded. www.statnews.com/2026/03/02/s...

Invasive Fungal Disease in Allogeneic Hematopoietic Cell Transplantation: New Risk Factors and New Therapeutic Options in a Changing World Abby P. Douglas, Monica A. Slavin First published: 02 March 2026 doi.org/10.1111/tid....

Invasive aspergillosis in liver transplant recipients in France (2007–21): a nationwide, retrospective, matched case–control study Coralie Le Hyaric, et al. Lancet Microbe, 2026. www.thelancet.com/journals/lan...

Rapid and reliable diagnosis of mucormycosis using colorimetric loop-mediated isothermal amplification | Journal of Clinical Microbiology @ecmmcandidaiv.bsky.social @galactic-europe.bsky.social journals.asm.org/doi/10.1128/...

LANCET Seminar Online Sepsis Mervyn Singer, et al. www.thelancet.com/journals/lan...

Transgenic mouse-derived human monoclonal antibodies targeting EBV gp350 and gp42 provide basis for therapeutic development Crystal B. Chhan, et al. Cell Reports Medicine (2026) www.cell.com/cell-reports...

Omeprazole Is Associated with Voriconazole-Associated Hepatotoxicity in 848-Patient Cohort Ding et al. www.sciencedirect.com/science/article/pii/S0924857926000385 • O, but not other PPIs, independently increases voriconazole hepatotoxicity risk • O-specific VRC Cmin cut-offs: 4.1 mg/L and 5.5 mg/L

How does treatment induced antibiotic resistance happen in real-world infections? We analysed 25k Pseudomonas isolates from 180 patients in a clinical trial to find out! TLDR: The ecological and evolutionary paths are surprisingly diverse & complex even in patients receiving identical treatment…

Pertussis Infection in Adults url: jamanetwork.com/journals/jam...

Precision dosing of systemic antifungals in adults: therapeutic drug monitoring, empiric dose optimization and barriers to implementation url: academic.oup.com/jac/article-...

The effect of pneumococcal conjugate vaccine and pneumococcal PSV on nasopharyngeal colonisation following human infection challenge with st 3 and st 6B (PREVENTING PNEUMO 2): a double-masked phase 4 RCT Liatsikos, et al. Lancet Microbe, 2026. www.thelancet.com/journals/lan...

The effect of pneumococcal conjugate vaccine and pneumococcal PSV on nasopharyngeal colonisation following human infection challenge with st 3 and st 6B (PREVENTING PNEUMO 2): a double-masked phase 4 RCT Liatsikos, et al. Lancet Microbe, 2026. www.thelancet.com/journals/lan...

Tissue Pharmacokinetics of Antifungal Drugs: A Review. Felix Bergmann, et al. International Journal of Antimicrobial Agents, 2026. doi.org/10.1016/j.ij...

Cost-Effectiveness of Once Weekly Rezafungin for the Treatment of Invasive Candidiasis in the United Kingdom Noemi Muszbek, et al. Mycoses, 2026. onlinelibrary.wiley.com/doi/10.1111/...

Adult obesity and risk of severe infections: a multicohort study with global burden estimates. Solja T Nyberg, et al. LANCET, 2026. doi.org/10.1016/S014...