Abstracts, Clinical Conundrums and FungArt for the Fungal Update conference in London (March 2026) are all now open for submission: mycologyconference.co.uk/abstracts/

Genomic epidemiology of Histoplasma in Africa Rutendo Mapingo ... @neleshg.bsky.social Daniel Matute Three genetically distinct lineages identified among African Histoplasma isolates journals.asm.org/doi/10.1128/...

Results from our CAST-NET cohort study published. Excellent national coverage of cryptococcal antigen screening in SA but real challenges to act on CrAg+ results to exclude meningitis and dispense pre-emptive antifungals journals.lww.com/jaids/abstra...

Jayne Ellis presenting data from our cohort with CD4 <100 undergoing CrAg screening in SA at #IAS2025 (poster 2803) 59% (86/146) had CMV viraemia - strongly & independently associated with ⬆️mortality, more than quadrupling odds of death at 6-months (adjusted OR 4.02, 95%CI 1.27-12.7)

During 2016–2023, among 21,195 US patients who tested positive for Candida auris skin colonisation, 6.9% were subsequently found to have a positive clinical specimen, 2.8% from blood Probably an underestimate but useful to know wwwnc.cdc.gov/eid/article/...

We brought together teams from 13 neonatal sepsis surveillance studies, conducted across 35 sites in South Asia and Africa, to pool data and estimate prevalence of capsule and O types amongst #Klebsiella pneumoniae causing sepsis in newborns, using Bayesian modelling.

I'm super happy to share this preprint on ‘Distribution of capsule and O types in #Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: meta-analysis of genome-predicted serotype prevalence and potential vaccine coverage’ doi.org/10.1101/2025...

Congrats to Serisha Naicker & our 🌍CryptoADAPT team at Wits, UP, SUN, Imperial, CISM, UZ, Duke for the new @wellcometrust.bsky.social grant Excited to dig into the environmental diversity of Cryptococcus in Africa www.wits.ac.za/news/latest-...

Must read from @stephanienolen.bsky.social @nytimes.com: From #SouthAfrica Built a Medical Research Powerhouse. Trump Cuts Have Demolished It. www.nytimes.com/2025/06/17/h...

Hosted by a full panel of trial investigators from the @effecttrial.bsky.social

Great updates and learning at the histoplasmosis working group meeting at the tail end of ISHAM triennial conference And new targets will be set...

Great to contribute to this week's Naked Scientist podcast on the rising tide of fungal diseases www.thenakedscientists.com/podcasts/nak...

Congratulations Lottie

"Considering this conflicting evidence, there is equipoise to support a clinical trial in which persons with AHD without overt symptoms suggestive of histoplasmosis and with Histoplasma antigenuria are randomized to pre-emptive antifungal therapy or to observation."

"How can WHO be expected to serve the whole world on the same budget as one hospital in a mid-sized European city?" www.statnews.com/2025/05/14/w...

Thanks for sharing. There was also a recent State of the Art review in CID on the topic academic.oup.com/cid/article/...

In 2008, my wonderful 84-year-old grandmother died in hospital with perforated diverticulitis. I was a newly-qualified clinical microbiologist then. When it became clear that she wouldn't recover, I asked for her to be transferred out of ICU, to receive palliative care and to stop antibiotics...

Bad news... "A draft budget for the department [HHS], obtained by The New York Times, proposes axing two journals published by the Centers for Disease Control and Prevention: Emerging Infectious Diseases and Preventing Chronic Disease."

Plasma Microbial Cell-free DNA Metagenomic Sequencing for Diagnosis of Invasive Fungal Diseases Among High-risk Outpatient and Inpatient Immunocompromised Hosts #IDSky

It's staggering what has unravelled in a matter of months

Fungi can protect the environment, grow food and even develop new medicines. 🍄 But they can also cause disease. As climate change spreads pathogenic fungi to new places, more people worldwide will be at risk. Learn more in our explainer ⤵️ wellcome.org/news/will-cl...

Nice cover of Emerging Infectious Diseases Journal, highlighting the still-mysterious fungal kingdom, a small % of which causes deadly human infections "Nature alone is antique, and the oldest art a mushroom" -https://wwwnc.cdc.gov/eid/article/31/5/ac-3105_article

Recruiting inpatients living w/ HIV into ADVANCE GERMS-SA cohort study in Johannesburg @raewake.bsky.social Screened 2000, enrolled >500 so far. Primary outcome: incidence severe infections AHD-associated sepsis & AMR summarised in a new @mbio.bsky.social mGem: journals.asm.org/doi/10.1128/...

Global pandemic treaty finalized, without U.S., in ‘a victory for multilateralism’ www.science.org/content/arti...

"How US funding cuts are threatening #SouthAfrican families living with #HIV" via @aljazeera.com

Differences in mortality in hospitalized advanced HIV disease between treatment-naive and treatment-discontinuing individuals: a comparative retrospective study from Mexico City ✅ Just Accepted #IDSky

A new analysis raises concerns over the stoppage of funding for this long-standing program, which could have major impacts on global public health for years to come. #HIV #IDsky #medsky

Outbreak detective stories are the best

Interventions to support people with HIV following hospital discharge: a systematic review ✅ Just Accepted #IDSky

We're pleased to announce the appointment of Prof Joe Jarvis as Honorary Professor at @exeter.ac.uk. Joe's expertise will complement our ongoing and future activities @mrccmm.bsky.social Read more: sites.exeter.ac.uk/medicalmycology/2025/03/13/prof-joe-jarvis-appointed-as-mrc-cmm-honorary-member/

What a wonderful venue to have a conference dinner at - and to see some old pals @drneilstone.bsky.social @neleshg.bsky.social - looking forward to some exciting fungal resistance talks tomorrow at #FungalUpdate2025

"It’s a pity that he’s never taken the time to truly understand the burden of disease in South Africa." www.statnews.com/2025/02/26/t...

Super exciting times whenever a phase III trial unblinds. Really great multinational group of HARVEST TB meningitis trial investigators. Incredibly fun to write up as a team together in rapid fashion. Protocol: doi.org/10.12688/wel...

New research article Pathogen aetiology and risk factors for death among neonates with bloodstream infections at lower-tier South African hospitals: a cross-sectional study www.thelancet.com/journals/lan... #IDSky #ClinMicro #OpenAccess #OA

We've described 907 episodes of neonatal infection in our latest Baby GERMS-SA paper Full text link here: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Defining & responding to contextual drivers for #AntimicrobialStewardship implementation in SA neonatal units enabled a multidisciplinary team approach to develop & optimise #AMS, with potential for other low resource settings: https://doi.org/10.1093/jacamr/dlae222 @neleshg.bsky.social #JACAMRNews

Grateful to @gregggonsalves.bsky.social for his inspiring work and words When ‘Just Asking Questions’ About Science Turns Into 300,000 Dead www.nytimes.com/2025/02/13/o...

New guidelines for diagnosis and management of candidiasis from ECMM in cooperation with @ishamycology.bsky.social and @asm.org Led by @olivercornely.bsky.social @rosannesprute.bsky.social with contributions from >100 experts Author link: authors.elsevier.com/sd/article/S... #IDSky

Some refugees are always welcomed in the Global North www.cbsnews.com/news/trump-o...

The US was considered a world leader in public health and research. With one repressive stroke that reputation risks being broken, argue @jocalynclark.bsky.social and @kamranabbasi.bsky.social www.bmj.com/content/388/...

Linda-Gail Bekker was beyond excited when #Pepfar announced in December that the fund will help get the jab to 2-million people. Now the new Trump administration will likely kill that dream, via @miamalan.bsky.social. bhekisisa.org/opinion/2025...

Proceedings of the 2024 AIDS-related mycoses meeting in Cape Town, SA We discuss advances, challenges, and future directions - full text link below authors.elsevier.com/c/1kNnb,L~yC...

We still don't know if TMP-SMX is the best treatment for HIV-associated PCP...new trials needed 14 trials, 1983-1996, 96% male participants, high-income countries, 9/14 w/ <100 participants, no other regimen superior, comparators less toxic www.clinicalmicrobiologyandinfection.com/article/S119...

Among 27 people w/ HIV-associated histoplasmosis (treated with amphotericin B), median Histo antigenuria levels measured by IMMY Clarus ⬇️from 35 ng/ml (26 EIA units) at diagnosis to 0.8 ng/ml (0.5 EIA units) at 6m. academic.oup.com/mmy/advance-...

Global Health’s Evolution and Search for Identity: "Today’s global health is essentially whatever the Global North characterizes as such." wwwnc.cdc.gov/eid/article/...

Nice paper. I would have expected the pairs of baseline and persistent C. albicans strains from 10 patients to have been sequenced. Perhaps a follow-up study...