My paper is out! Uncovering hundreds of exogenous and endogenous RNA viral RdRp sequences amongst uncharacterised sequences in public protein databases. doi.org/10.1093/ve/v... 💻🧬 1/5 🧵

I translated "Jeff Jet: Abenteuer InfoHighway" as "Jeff Jet: Adventure on the InfoHighway" archive.org/details/jeff... - a German promotional adventure game for Hewlett Packard from 1995.

Come to the BOKR session at 2:20 and see Charlotte Tumescheit @schnamo.bsky.social give a super interesting talk about improving prediction of molecular properties by incorporating ontologies. #ISMBECCB2025

Someone needs to implement an LLM to help select which talks to go to at #ISMBECCB2025

Come and see me in the ice rink if you want to plot phylogenies in matplotlib! Poster 206. GitHub.com/KatyBrown/plot_phylo #ISMBECCB2025

I reformatted the #ISMBECCB2025 schedule a bit - in case anyone else wants to use it this way - ordered by day and start time: csv: drive.google.com/file/d/1JyhT... xlsx: docs.google.com/spreadsheets...

Excited for the ISMB/ECCB conference! I have two posters A520 today about an endogenous and exogenous virus I found in nematodes - and B206 tomorrow about my tool plot_phylo for drawing phylogenies in matplotlib. #ISMBECCB2025

Is it so much to ask for all my bullet points to be 1. the same size and 2. in a straight line?

I could do my job in half the time if we just picked a column delimiter and stuck with it and then no-one can use that symbol for anything else. Let's not use * to both delimit columns and represent a stop codon, or use a random number of spaces, or put "_" in our sequence IDs. 🖥️🧪

From student to researcher, a #career in #science can come with a high price tag. @drcraigmc.bsky.social explores how wealth shapes opportunity in #STEM and proposes structural changes to support #equity and inclusion. 🧪 plos.io/4edGlY4

There should be a ban on broadcasters using footage of “anonymous” (heads cropped out) larger people - who could nevertheless recognise themselves based on knowing their own bodies and clothes - to illustrate stories about obesity, fat or weight loss

Are you interested in using AI to decode RNA? Have a look at this brilliant new review from my friend @schnamo.bsky.social and her colleagues.

Just a reminder to please fill out this form if you’d be interest in an EVE / ERV meeting 📋🥳

NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.

@ariskatzourakis.bsky.social @robjgifford.bsky.social @lequimelab.eu @emma-harding.bsky.social

I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics

"Action in Hollywood" is one of several promotional games released in the 1990s for Bi-Fi Rolls, a salami-based snack originating in Germany and sold across Europe.

I translated "Bi-Fi: Action in Hollywood" (1994) for MS-DOS, one of the more ambitious and fully-developed promotional games of the era. Huge thanks to @sonneveld.bsky.social for helping me with the technical aspects on this one. archive.org/details/bifi...

Excited for #RdRpSummit2025 and #ViBioM2025! Just starting off now in Lisbon.

Here we go! The #RdRpSummit2025 is live! @ingrida.bsky.social

v1.0 of "King's Quest 1: Rubber Tree Edition" is up! Apply the mod here: denzquix.github.io/agi-patch/ You will need the files from the non-enhanced DOS version. The patched files will run in ScummVM under the "Fan AGI" option, or in DOSBox if you include other files from the original game folder.

Visit our posters at #RECOMB2025 for: Structural: MSAs, Virus DB, Core Genes, Motif Discovery, Multimer Clustering & Search, pLM Foldseek, Environmental analysis Metagenomics: Classification & Metabuli App GPU-based & RNA search, Proteome clustering, Novel Ribozyme discovery & get Marv stickers!

I've never related to a plant more.

It's also the day for my favorite meme! If this aging Klingon warrior can get it right, so can anyone.

Just finishing something for a paper I was planning to submit in 2013.

We have an incredible growing ecosystem of #python tools that you should check out!! Welcome plot_phylo to our ecosystem !! #openscience #science #opensource

The abstract submission & registration for #RdRpSummit2025 is NOW OPEN!!! 🎉🙌 Do you work on RNA virus discovery using RdRps? Are you joining the #ViBioM2025 in Portugal? Consider submitting your research in one of our sessions! More info: RdRp.io

The number of people surprised by the long list of words NSF is targeting makes me think many of you all have not seen this: www.commerce.senate.gov/services/fil...

My tool plot_phylo is now available through @pyopensci! Used to plot a phylogenetic tree using matplotlib functionality, so mpl can be used for additional annotation. Very smooth and helpful process with lots of useful feedback. www.pyopensci.org/python-packa... github.com/KatyBrown/pl... 🧪🧬🖥️

Hello Bluesky community :) Would like to take this opportunity to draw your attention to some selected bioinformatics work I did together with @thekatybrown.bsky.social, if you are dealing with multiple sequence alignments it might be useful! peerj.com/articles/129...

I translated "Croustibat" (1995), made by Coktel Vision - re-using the engine from "Gobliins 2: The Prince Buffoon" - to promote Findus' line of frozen fish fingers/fish sticks. Many thanks to Fred_PJ for preserving the original Portuguese version. archive.org/details/crou...

Is anyone going or has been before to the "Festival of Genomics" at the ExCeL #FOG2025? Is it fun? Should I go? 🧪

My crocheted Christmas wares, UK Christmas dinner themed tree decorations, for my MIL to sell at her church Christmas fair on Saturday www.eventbrite.co.uk/e/st-giles-c...

Live now with some DOS advergames as well translated by the good @denzquix.bsky.social

Computational biology. It's always more complicated

This is really cool, maybe someone (someone patient i.e. not me) should do the same for RNA viruses 🤔🕷️

ChatGPT is good at choosing colours and gives you a hilarious description as a bonus. "RdRp is labelled in optimistic gold and other viral genes in an approachable coral".

Sending out job rejection emails at 1am is a great way to give people a night doubting every aspect of their life.

#PhD Advert: Please share! Are you looking for a PhD studentship in comparative- or population-genomics, using 300+ species of #Drosophila and 1000+ genomes of #melanogaster? #Entomology #Genomics #PopGen #Phylogenetics

🧪 Academics verifying Bluesky using ORCID IDs Nice idea! 😊 ⬇️

MMseqs2 Release 16 Highlights: GPU-accelerated search📄, ORF or new 6-frame translated search modes, contig taxonomy always keeps the longest ORF, bug fixes (reduced memory and higher sensitivity) and relicensed as MIT 📄 biorxiv.org/content/10.1... 💾 mmseqs.com and 🐍Bioconda 🖥️🧬🧶

Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web. 🌐 bfvd.foldseek.com 💾 bfvd.steineggerlab.workers.dev 📄 academic.oup.com/nar/advance-...

I had a dream last night that Elon Musk had lots of ideas, all stored in paper bags, and @denzquix.bsky.social and I were filling the bags with katsu sauce so he couldn't carry them out.

My taller half @denzquix likes to translate obscure promotional video games in his spare time - if anyone lacks a (slightly frustrating) fishfinger-themed monster-bashing adventure game in their life, I'd recommend this one, and only partly because the English edition character is named after me.

Does anyone know of an endogenous retrovirus / endogenous viral element starter pack? I can't find anything in the directory. I'm too out-of-date to create it I think.

Just reposting this myself since I have about 400 more followers than I did on Saturday!

I made a quick Starter Pack for scientists working on virus discovery - please reply if you’d like me to add you to the pack (or remove you) or to recommend anyone! #scisky go.bsky.app/HK1wxRb

I have developed (with @denzquix.bsky.social) a Python package to plot phylogenetic trees onto an existing matplotlib plot - so annotations can be added using mpl functions and figs with phylogenies can be automated. Please try it! github.com/KatyBrown/pl... or pip install plot_phylo

Cruliviridae doi.org/10.1099/jgv.... Discoviridae doi.org/10.1099/jgv.... Leishbuviridae doi.org/10.1099/jgv.... Mypoviridae doi.org/10.1099/jgv.... Tulasviridae doi.org/10.1099/jgv.... Wupedeviridae doi.org/10.1099/jgv....