Now published - the #BANC! A full central nervous system (CNS) connectome of a limbed animal at single-synapse resolution, enabling us to follow sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS. #neuroscience. Video by @quorumetrix.bsky.social 1/18

In vivo evidence that full-length Slits have biologically distinct activities compared to the proteolytic fragments. Cultured DRG axons branch in response to Slit2-N and this is opposed by Slit2-FL. In vivo, Slit2-N appears to promote fasciculation, not repulsion. bsky.app/profile/dev-...

Understanding the Genetics of Autism www.brainfacts.org/diseases-and... - a primer I wrote for @brainfacts.org to try and counter the pseudoscience around autism by explaining what we actually know about the (complex) genetics of the condition

Pygmy Nuthatch @unr-biologybuzz.bsky.social

New #Robo #Slit antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric #recombinantproteins are specific to human and mouse targets and do not cross-react with other family members. #axonguidance #neuronalmigration buff.ly/mtViWPa

Hot off the press: The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience: rdcu.be/ek010

Check it out at PNAS today. Thank you Alexandre for the collaboration!! PK Mem probes offer long time-lapse imaging of cell membrane dynamics. Made possible by Jing Ling, Yitong Liu, and all the collaborators! Available @spirochrome.com

This isn't a coincidence, IMO. The fly community is generally super rigorous - because there are so many tools and techniques available, people expect you to really nail things in order to get published (and keep getting funded)

Visitor at work today @unr-biologybuzz.bsky.social

This time-lapse captures 17 hours of axonal growth from a chicken dorsal root ganglion explant, visualized through the actin cytoskeleton using live confocal imaging. I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! 😉 🧪

You maybe interested in this film I made in a very remote part of Tibet while I was doing my PhD in Developmental Biology, shown on BBC2 in 1988. A pilgrimage to Mount Kailas - the centre of the universe to Tibetan Buddhism. youtu.be/ls4doaxVBkg

We are pleased to report publication of the Drosophila circadian clock connectome in @naturecomms.bsky.social. Check out the final version for additional analyses not present in the preprint. @unrcabnr.bsky.social www.nature.com/articles/s41...

For this #FluorescenceFriday, let's watch an axonal growth cone (for a change) displaying its most beautiful filopodia (this time)! 🤩 They are so dynamic! 1 image taken every 500 ms for 5 min played at 15 fps. 🧪

Please retweet! Open rank faculty search in the basic sciences at UCLA David School of Medicine. Multiple positions are available - the application deadline is 19th January. Please apply here: recruit.apo.ucla.edu/JPF10062

#FörsterLab #ZandawalaLab #YoshiiLab #circadianClocks #connectome #Drosophila #chronobiology @nils-reinhard.bsky.social @zandawala.bsky.social

rdcu.be/d2vIj Synaptic connectome of the Drosophila circadian clock

Let's unleash the axonal growth cones for this #Fluorescencefriday ! #neuroscience #Liveimaging #microscopy #Axonguidance

May commissural axons find their way in here 🙏 #Microscopy #LiveImaging #AxonGuidance #Neuroscience

These Pooh and Piglet neurons are #lost without ROBO receptors. More about the wonders of axon guidance: axonology.com/how-to-build... #SciArtSeptember #SciArt #neuroskyence 🧪