A new study shows MTB surveillance and transmission can be resolved without culture or capture-based enrichment, using nanopore WGS directly from sputum. www.biorxiv.org/content/10.1...

Long-read single-cell RNA sequencing on nasopharyngeal swabs from COVID-19 patients; authors were able to identify differences in splice isoforms for genes that modulate immune signaling and apoptosis.

Interesting news in the world of transposable elements. Discovery of "a novel clade of Helitrons, with 9-10 kb transposase ORFs under purifying selection, that have remained active" in Paramecium aurelia. www.biorxiv.org/content/10.1...

Long-read de novo assemblies for 5 paracoccidioides fungal pathogen species endemic to Latin America. (P. brasiliensis, P. americana, P. restrepiensis, P. venezuelensis and P. lutzii) www.biorxiv.org/content/10.1...

"This work validates ONT long-read sequencing as a powerful tool for marine microbiome studies to catalyze advancements in the fields of ecology and evolution, resource management, and conservation" www.biorxiv.org/content/10.1...

Very cool to see the early results of nanopore sequencing of PEPTIDES! The ability to perform genomics, transcriptomics and proteomics on a single platform is incredibly exciting, and the potential for future applications is massive. www.biorxiv.org/content/10.1...

Not sure which tick reference genome to use for your analysis? This paper provides a very nice assessment of 34 high-quality tick genome assemblies from 21 species. www.biorxiv.org/content/10.1...

Using long reads that can span the length of telomeric regions, researchers developed a method to measure telomere length in S. cerevisiae, and found wide variation in telomere length, ploidy, and subtelomere structure. buff.ly/hGM08qS

Long-read WGS of 48 L. infantum identified drug-resistance biomarkers in 80% of the isolates! "Leveraging WGS, our approach provides a methodological advantage by complementing CNV analysis with detailed read sequence profiling " buff.ly/LRIDrOr

Potentially useful new tool for targeted microbial genomics. - Toolkit to design selective WGA (sWGA) primers - ~99% on-target reads + strong genome coverage when tested with P. falciparum samples - Validated with long read Oxofrd Nanopore sequencing

🧬 Now published in Bioinformatics Advances: "Snappy: Fast identification of DNA methylation motifs based on Oxford Nanopore reads"   Full article available: https://doi.org/10.1093/bioadv/vbaf296

Long read Metagenomics, #phage and #prophage in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years #phagesky www.nature.com/articles/s41...

Very pleased to have been able to participate in this, and looking forward to hearing more about the participants' future work!

🔬 L’équipe de Sciensano dirigée par Margo Maex remporte le #BSFM2025PosterAward 🏆 pour ses travaux sur l’usage d’Oxford Nanopore Technologies dans la surveillance de Salmonella. Une avancée vers une #surveillance plus rapide et intégrée en #microbiologie !

Nanopore-based ITS2 sequencing maps the global distribution and diversity of human-infecting whipworm (Trichuris) @pschneeb.bsky.social @noordeen24.bsky.social @swisstph.ch‬ #parasitology #whipworm

Our manuscript comparing Nanopore vs. Illumina reads for population-level variant calling and genotyping is now out: journals.asm.org/doi/10.1128/... . This work was led by Andrea Schiffer and @arftrhmn.bsky.social.

📢 Save the Date! The 2nd Nanopore Users Day will take place 🗓️10 March 2026 at the Duclaux Amphitheater, Institut Pasteur (Paris). This edition will be open to external participants! 👉 More details and registration info coming soon! @chloebaum.bsky.social @pasteur.fr @nanoporetech.com

Countering illegal wildlife trade needs rapid, reliable species ID in places such as airports. This study describes VeRIF-ID, a portable nanopore DNA method that identifies vertebrate species on-site with >91 % accuracy, offering a fast, low-cost tool against trafficking.

See how researchers are detecting species in real time using portable Oxford Nanopore sequencing. Learn best practices for eDNA collection to uncover hidden communities — without the need for observation. Join our live webinar tomorrow. https://bit.ly/47RharD

A streamlined nanopore-compatible 5PSeq protocol for rapid phenotypic antimicrobial sensitivity testing https://www.biorxiv.org/content/10.1101/2025.11.12.687992v1

Join the Oxford Nanopore Sequencing Symposium at Life Sciences SR1 on 20 Nov 2025 (10:00–15:00). Talks, networking, free pilot project contest & lunch. Hosted by @cgr-uol.bsky.social Register: nanoporetech.swoogo.com/Nanopore_X_L...

RNA Virus Journal Club – Upcoming Talk - this thursday (Nov 6th !) With @rdrpsummit.bsky.social - excited to announce talk and discussion with Dr Sanguu Kim about HF nanopore sequencing strategy for virology :) calendar.app.google/oyRVP6v5Tvjg... CET: 14:00–15:00, Format: 30 min + 30 min

Identification of Capture Phases in Nanopore Protein Sequencing... arxiv.org/abs/2511.0... --- #proteomics #prot-preprint

Establishing benchmarks for quantitative mapping of m6A by Nanopore Direct RNA Sequencing doi.org/10.1101/2025...

“MARTi has its origins in software we developed for really rapid identification of #pathogens in preterm infants, but we’ve since adapted it to use in a wide range of settings...including in agriculture, and biosurveillance..." A powerful new tool for real-time analysis of #nanopore #metagenomics 👇

Upcoming seminar by Ali HAMRAOUI: Les approches bioinformatiques pour l’etude des isoformes en transcriptomique cellule unique couplee au sequencage Nanopore at IBENS, Thursday 06 November 2025 at 14:00. More info

Join us next week for "Transforming Tumor Methylation Profiling with Oxford Nanopore Direct DNA Sequencing" on October 28, 2025. Click here to learn more and register today: buff.ly/Oxz6OQh

Sampled the Winogradsky column today in 6 places and extracted DNA. Looking forward to seeing how much DNA we extracted and Nanopore 16S metabarcoding on Friday.

A new study in @plosone.org finds portable nanopore eDNA sequencing recovers comparable biodiversity signals to Illumina in resource-limited settings, increasing accessibility for biodiversity monitoring. doi.org/10.1371/jour...

My lightning talk on “Uncovering Genomic Diversity in the African Diaspora via Long-Read Nanopore Sequencing” will be presented at 1:45 PM in Room 206AB (Level 2). #ASHG25

Validation of High-throughput Oxford Nanopore Technology for HIV-1 Transmitted/Founder Virus Identification https://pubmed.ncbi.nlm.nih.gov/41109409/

Our abstract submissions for London Calling 2026 are now open! If you’ve been using Oxford Nanopore technology to power the bigger and bolder research questions, we want to hear about it. Submit your abstract here: nanoporetech.com/about/events... #nanoporeconf

📣New from Wang & colleagues! 📑Fine Mapping Regulatory Variants by Characterizing Native CpG Methylation with Nanopore Long-Read Sequencing 👉 bit.ly/4o8qMoY

New paper from our ultra-rapid WGS project published @ejhg-journal.bsky.social : "Nanopore long-read sequencing for the critically ill facilitates ultrarapid diagnostics and urgent clinical decision making" #raredisease #WGS @nanoporetech.com @erasmusmc.bsky.social www.nature.com/articles/s41...

2️⃣ 4️⃣ hours left until our microbial amplicon barcoding webinar! Learn how to sequence full length 16S and ITS genes with Oxford Nanopore's latest kit. Recordings also sent out after signup. nanoporetech.com/about/events... #16S #ITS #metagenomics #metabarcoding

Hope you had a chance to chat with Max at @nanoporetech.com Biopharma Day Philadelphia. We had a great time discussing: - Plasmid EZ: Easy as 1, 2, 3 - Nanopore Technology Applications at Azenta Life Sciences - Benefits of mixed platform multiomics #BiopharmaDay #Nanopore #NGS #ONT

"near-complete de novo assembly of chromosomes and plasmids by long-read nanopore sequencing allowed for high-resolution strain identification, plasmid profiling, and antibiotic resistance gene detection" www.biorxiv.org/content/10.1... #AMR #Nanopore #PublicHealth #GenomicSurveillance

Cool talk on microbial isolation and metagenomics at Kalk Bay in S. Africa, to screen previously uncharacterised genomes to search for novel antimicrobial compounds 📺 You can watch here: www.youtube.com/watch?v=t5cQ... #LongReads #AMR #antimicrobial #metagenomics #microbiome #nanopore

Just under 6 weeks until the metagenomic virus discovery workshop kicks off in Stellenbosch, South Africa. We're excited to be bringing together a fantastic group of speakers and teachers with expertise in all aspects of virus discovery from around the world.

New TB genomics study! Culture-free Mycobacterium tuberculosis WGS using nanopore sequencing directly from sputum. Faster, simpler, and actionable for public health. biorxiv.org/content/10.1101/2025.09.23.678181v1 #NanoporeSequencing #Genomics #TB

We examined Oxford Nanopore 16S amplicon sequencing as a tool for recovering marine microbial communities and we are pleased with the results! Check out our preprint 🌎🧪🧬🌊🖥️🦠https://www.biorxiv.org/content/10.1101/2025.09.20.676612v2.abstract

16S rRNA gene and rpoB Nanopore Sequencing for Bacterial Detection and Identification in Clinical Samples https://www.medrxiv.org/content/10.1101/2025.09.30.25336965v1

Webinar: Squiggles to the Rescue: Nanopore Sequencing and AI for Rapid One Health Surveillance Join us as Dr. Lara Urban explores how nanopore sequencing and AI can empower rapid One Health strategies. Thursday, Oct. 23, 2025, 11:00 AM PT Register Now: www.zymoresearch.com/pages/squigg...

Limited places now remaining for our #nanopore #metagenomics workshop! buff.ly/tCB0Zeu #MAGS #nanopore #eDNA 🧬💻

(For people who don’t know - I’m a long established consultant to Oxford Nanopore and a shareholder. No company vets my social media posts)

To summarise our recent pre-print: Autocycler, the automated consensus assembler, when used with Nanopore long-read only Enterobacterales assemblies, produces more complete chromosomes and plasmids, with an accuracy comparable to hybrid assemblies.

🚀 We’ve just kicked off the 4th edition of our Genome Assembly course with the fantastic team at @nanoporetech.com For the next few days, participants from all over the world will dive into the latest strategies, tools, and hands-on practice for assembling and polishing genomes with #Nanopore data🧬

💬 "This course provided me great detail of general aspects that are crucial to understanding #metagenomics covering technical aspects of the use of #ONT platform and interface." Keen to learn about lab and in-field @nanoporetech.com metagenomics? 👉 buff.ly/tCB0Zeu #MAGS #nanopore #eDNA 🧬💻

You can't just pull data out of thin air. Or can you...? That's exactly what Craine et al. did in Panama, through air sampling and airDNA metabarcoding, detecting ~1800 arthropod and vertebrate OTUs. www.biorxiv.org/content/10.1... #nanopore #airsampling #metabarcoding #biodiversity

TIL about endofungal bacteria! Mycetohabitans spp. are bacterial endosymbionts of the fungus Rhizopus microsporus. Abbot et al. assembled 28 complete genomes including chromosomes, chromids and mobilome-rich plasmids. www.biorxiv.org/content/10.1... #nanopore #plasmidsaurus