Chloé Baum (@chloebaum.bsky.social)

Computational analysis of DNA methylation from long-read sequencing Nature Reviews Genetics, Published online: 28 March 2025; doi:10.1038/s41576-025-00822-5Long-read sequencing technologies can directly profile methylation modifications across the genome. In this Review, Fu et al. overview the long-read computational tools to identify and compare methylation signals, as well as tools that use these methylation signals to analyse cell-type diversity and gain additional genomic insights. https://www.nature.com/articles/s41576-025-00822-5?utm_source=dlvr.it&utm_medium=bluesky