University of British Columbia and NEB scientists directed an aglycoside hydrolase to evolve an increased ability to cleave the sialyl T-antigen and used ultrahigh-throughput screening method to uncover enhanced variants. https://pubs.acs.org/doi/10.1021/acscentsci.5c01227

@liverpooluni.bsky.social and NEB researchers used Cappable-seq to observe differential expression in response to stressors in Wolbachia, providing insights for mosquito control. Learn more in Microbial Genomics: https://nebiolabs.com/3YPZ1X0

Cornell University and NEB researchers used High-Complexity Golden Gate Assembly to develop an engineered bacteriophage biosensor that can detect E. coli in drinking water samples. Read more in American Chemical Society: https://pubs.acs.org/doi/10.1021/acssynbio.5c00665

In a new protocol, NEB researchers detail steps for preparing standard solutions, building calibration curves to identify and quantify RNA modifications by LC-MS/MS, and how to efficiently convert RNA to nucleosides and perform sample analysis. https://nebiolabs.com/4jbP7bw

Like a snowflake, science is unique, intricate, and shaped by countless unseen forces. Thank you for your continued support, and may we continue to shape science together in 2026. #shapingscience

Find your ideal total RNA isolation kit for higher throughput and prep needs with Monarch! The Monarch Spin RNA Isolation Kit (Mini) now offers a 200-prep size to meet your needs 🦋 https://nebiolabs.com/4p42BYp

Look forward to the upcoming year in science with 2026 predictions presented by @biocompare.bsky.social, including a highlight from NEB Executive Director of Research Tom Evans on clinical diagnostics! https://nebiolabs.com/491IaVQ

Looking for highly pure E. coli tRNA for your cell-free protein synthesis or other research applications? Our newly released E. coli tRNA is isolated and purified without organic solvents, ensuring exceptional performance across diverse template sequences. https://nebiolabs.com/4aoMIrU

@mrclmb.bsky.social is #shapingscience by tackling fundamental research problems. In their Science article, Robertson et al. reengineered the genetic code of E. coli through total genome synthesis to create a 57-codon genome. https://www.science.org/doi/10.1126/science.ady4368

Learn how RNA therapeutics move beyond their vaccine-based origins in a recent editorial by GEN featuring Nicole Nichols, Ph.D., NEB executive director of applications and product development: https://www.genengnews.com/topics/bioprocessing/beyond-vaccines-scaling-the-promise-of-rna-therapeutics/

Durham University (@durham.ac.uk) and NEB scientists described the first biochemical characterization of GmrSD Type IV restriction enzyme substrate specificity and inhibition by phage protein IP1*. https://royalsocietypublishing.org/doi/10.1098/rstb.2024.0072

Only need to isolate a few RNA samples and looking to reduce unused reagents? The Monarch Spin RNA Isolation Kit (Mini) now comes in a convenient 10-prep size to suit your volume needs. https://nebiolabs.com/4pyQPpZ

Science builds a greener, healthier & more compassionate world. The 2024 Passion in Science awards honored some “unsung heroes” of the lab, including 5 Science Mentorship & Advocacy Awardees #shapingscience by advocating for and mentoring scientists of tomorrow: https://nebiolabs.com/4oqEZwB

Get a head start on organizing for 2026 by requesting a free copy of our upcoming calendar filled with beautiful photos from your fellow scientists: https://nebiolabs.com/3Y1Msaz

In collaboration with University College Cork and others, NEB scientists describe a long-running study of RM systems in Lactococcus species. Read more in Nucleic Acids Research: https://academic.oup.com/nar/article/53/17/gkaf854/8249855

In our latest podcast (https://nebiolabs.com/3KxkfoY), hear from Cynthia Ziwawo, M.D., Geoff Hutchinson, and Olubukola Abiona, whose collaborative work shaped the future of vaccines by developing the first COVID mRNA vaccine. #shapingscience

Ready for a streamlined PCR & #DNAcleanup option? Our new Monarch Mag PCR & DNA Cleanup Kit (5 μg) (https://nebiolabs.com/4rPTMnE) uses a bind/wash/elute workflow for ssDNA and dsDNA with automation-friendly magnetic beads to eliminate the need for centrifugation or vacuum-based processing. 🦋

Using a phage-inspired genetic screen and biochem, NEB, Harvard Medical School, and University of Illinois Urbana-Champaign researchers discovered OLD inactivates tRNAs by a completely novel mechanism: severing anticodon arms! https://nebiolabs.com/4rysTEk #tRNA #PhageDefense

With the NEBNext Flu A Integrated Indexing Primer Module (https://nebiolabs.com/4nSxUES), your Flu A cDNA synthesis & library prep is seamlessly compatible with the Monarch Mag Viral DNA/RNA Extraction Kit and LunaScript Multiplex One-Step RT-PCR Kit. Go from sample to sequence ready faster!

#SynBio is often limited by how quickly & affordably researchers can synthesize custom DNA. Learn more about a web tool & workflow NEB scientists developed, bypassing outsourced DNA & enabling labs to produce sequence-verified constructs in just 4 days at lower cost. https://nebiolabs.com/48auZBo

Sequencing Influenza A from wastewater samples can identify outbreaks before they impact the healthcare system. NEB teamed up with Ceres Nano to show how its NEBNext Flu A Integrated Indexing sequencing workflow could be enhanced with Nanotrap Microbiome A Particles https://nebiolabs.com/4i9KQVt

Check out poster TT065 this morning at #AMPath2025, where Vaishnavi Panchapakesa, Ph. D. Will present on NEBNext enzymatic solutions for DNA methylation profiling of damaged DNA inputs!

Stop by poster ST156 this morning at #AMPath2025 to learn about how integrating whole exome sequencing and RNA-seq can facilitate somatic mutation detection in tumor tissue samples, presented by Margaret R. Heider, Ph.D.!

Don’t miss poster TT054 at the #AMPath2025 poster session this morning to learn about high-throughput methyl-binding domain-based DNA enrichment and sequencing from Kaylinnette Pinet, Ph.D.!

You may have noticed that - cough - #Influenza season is here. The NEBNext Flu A Integrated Indexing Primer Module is here to support infectious disease surveillance & #NGS. Whether you’re monitoring wastewater, raw milk or clinical samples, sequence with confidence! https://nebiolabs.com/4nSxUES

Join NEB’s #AMPath2025 Innovation Spotlight session in Theater 1 at 4:25 pm today and learn from Nathan Tanner, Ph.D., how NEB is “Powering the Next Generation of Diagnostics with Enzyme Engineering and Design!”

Don’t miss our 10 am #AMPath2025 corporate workshop in Room 155 and hear the latest from Nicole Nichols, Ph.D. on how NEB scientists can support your assay development needs!

Come to our #AMPath2025 corporate workshop at 9 am in Room 155 to learn how NEB scientists teamed up with Brigham and Women’s Clinicians to develop a rapid assay for blood-based cancers!

Interested in how LAMP can enable molecular diagnostics? Stop by NEB at booth 336 to talk to our scientists! https://www.neb.com/en-us/applications/dna-amplification-pcr-and-qpcr/isothermal-amplification

If you're attending #AMPath2025 in Boston, check out the full lineup of NEB events in our new press release. Hope to see you there! https://nebiolabs.com/4hT4K6Z

Navigating product development within regulated markets? In a new Q&A with GEN, NEB Customized Solutions Director John Pezza and NEB Director of Global Operations Mike Pelletier discuss what you should expect from a reagents partner: https://nebiolabs.com/490g0fD

Looking for a new partner in customized solutions for your molecular diagnostics? Talk to the NEB team at #AMPath2025 at booth 336 to learn how we can help you find the perfect fit for your NGS, amplification and nucleic acid purification needs.

Getting ready for #AMPath2025? Make sure to stop by booth 336 to hear about how we can help you with your molecular diagnostics workflows!

Learn how you can develop molecular workflows using DNA modifications in our blog by Ashley Luck, Ph.D., NEB Associate Director of Applications and Development: https://nebiolabs.com/4hqlylF

NEB is excited to announce that the winners for the 2026 Calendar Contest have been chosen! There were so many great photos to choose from, and we thank everyone who submitted. We appreciate the support to help make next year's calendar!

Revisit our blog post demystifying Golden Gate Assembly! Learn when and how to use it and gain everything you need to add this powerful cloning method to your toolbox: https://nebiolabs.com/4pTjS83

Using or intrigued by the concept of a single/universal annealing temperature in your #PCR? Our recent application note explores this topic and how it can be used with Q5. Read more: https://nebiolabs.com/4o3h6M0

Ready to learn more about a rapid, cell-free workflow that streamlines the DNA design to protein purification process? Don’t forget to register for our webinar tomorrow at 1 pm EDT! https://nebiolabs.com/46cLLz0

In our latest blog, "Advancing DNA Barcoding at the Royal Botanic Garden Edinburgh," (https://nebiolabs.com/48BWpSD) learn how Nattanon Meeprom, Ph.D., surmounted sample challenges to accelerate data collection as part of a team evaluating Saudi Arabian ecosystems

In our latest podcast (https://nebiolabs.com/3Wbbsv8), NEB bioinformaticist Vladimir Potapov talks through the open access Ligase Fidelity Tools which are used to aid in the design of DNA Assembly with the Golden Gate Assembly method.

Looking for new solutions to express protein quickly and efficiently? Join us for our webinar Oct. 1 at 1 pm EDT (https://nebiolabs.com/46cLLz0), where we’ll guide you through a rapid cell-free workflow to express your proteins of interest with confidence.

There’s still time to register for our upcoming webinar tomorrow at 1 pm EDT all about getting the most out of your NEBuilder HiFi DNA Assembly reactions! https://nebiolabs.com/46cLLz0

Don’t miss our upcoming webinars on Sept. 24 and Oct. 1 to learn more about NEBuilder HiFi #DNAAssembly and how to streamline your assembly to #proteinsynthesis workflow with #CFPS! https://nebiolabs.com/46cLLz0

Ready to get the most out of NEBuilder HiFi DNA Assembly? Register for our webinar on September 24 at 1 pm EDT, where you’ll learn more about NEBuilder HiFi’s advantages and strategies to optimize your reactions for maximum efficiency and success. https://nebiolabs.com/46cLLz0

Fall is fast approaching in the Northern hemisphere and along with it comes Viral Respiratory Illness season. Be ready with the NEBNext #RSV Primer Module: https://nebiolabs.com/3HZayOZ #NGS

Researchers at Albert Einstein College of Medicine investigated how TET3 mediates stem cell homeostasis during hemaopoiesis; An excellent showcase for NEBNext EM-seq™ and NEBNext E5hmC-seq™! https://pmc.ncbi.nlm.nih.gov/articles/PMC12053453/

Missed our live webinar on using the NEBExpress Cell-Free E. coli Protein Synthesis System for quick, easy in vitro #proteinexpression? View the recording for more on #CFPS & increasing workflow efficiency through template design, experimental flexibility & automation. https://nebiolabs.com/4617BW4

Thank you to everyone who attended the West Coast NEBNext User Group Meeting! We had a great time meeting our #NGS community, listening to our amazing list of speakers and talking all things next-gen sequencing.

#NEBNext products aren’t just trusted — they're published. With over 35,000 scientific peer-reviewed publications featuring NEBNext, researchers around the world are turning data into discovery. We’re proud to support your breakthroughs, every step of the way. What will you discover Next? #NGS

Recent findings from the ukbiobank.bsky.social Whole-Genome Sequencing Consortium are providing the deepest analysis of the human genome to date. We’re honored that they trusted NEBNext Ultra II PCR-free reagents for the monumental task! https://www.nature.com/articles/s41586-025-09272-9