To do no harm, we must first “know harms” Our new perspective piece on the challenge of measuring and reporting adverse events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social

www.medrxiv.org/content/10.1... INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.

To do no harm, we must first “know harms” Our new perspective piece on the challenge of measuring and reporting adverse events in interventions for pain is now available in @painthejournal.bsky.social dx.doi.org/10.1097/j.pa... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social

📣 Save the date for the 12th PCI webinar on September 18, 2025, at 4 PM CET!! Dorothy Bishop (@deevybee.bsky.social) will present "Editors matter: How negligent publishers subvert quality control in scientific publishing ". For more details and registration, visit:

@efic.bsky.social @britishpainsoc.bsky.social @auspainsoc.bsky.social

Out today 🚨 Our Cochrane review of 67 RCTs finds no clear evidence of benefit for ketamine or other NMDA antagonists for chronic pain. IV ketamine associated with risk of psychotomimetic effects, nausea, and vomiting. doi.org/10.1002/1465...

The ENTRUST-Pain Evidence (Entrust-PE) is an important initiative to ensure that pain science is of high quality. Framework published in J Pain. Endorsed by @iasp.bsky.social & @efic.bsky.social. More here: m.entrust-pe.org #pain

Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: www.jpain.org/article/S152...

Led by Prof. Neil O’Connell and funded by ERA-Net NEURON, ENTRUST-PE brought together an international network to co-create a new framework for trustworthy pain research. Learn more: entrust-pe.org #ENTRUSTPE #ChronicPain #ResearchIntegrity #EquityInResearch #PainResearch #NEURON #SuccessStory #RRI

📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research. ja.ma/4fzMVZS

Excellent, insightful conversation on the What the REF podcast between @simonhettrick.bsky.social and Marcus Munafo (@ukrepro.bsky.social) covering REF, open and transparent research and research culture (also rowing) youtu.be/uHRQjNqY6CY

An expression of concern for an RCT 2 years after we raised concerns around the trustworthiness of the data. pubmed.ncbi.nlm.nih.gov/40709807/ this trial influences guidelines www.sciencedirect.com/science/arti...

Be angry

👉Predatory Conference Check List 👈 ...based on my experience in detecting difficult cases, I did my own list for our group, as I was missing some points in those available... anyway, I'm happy to get suggestions etc. #researchintegrity #PredatoryConference download: www.uv.es/jogiers/pdf/...

Have you wanted to understand what is meant by “trustworthy” research? Attend this #webinar TODAY to hear from @davidhosch.bsky.social, @neiloconnell.bsky.social, @jdwilko.bsky.social, @nadiasoliman.bsky.social, @lesleyuttley.bsky.social bit.ly/4kSQjjy

Nice piece from Nadia Soliman and Michael Ferraro in MJA Insight on the state of the evidence for the management of neuropathic pain: insightplus.mja.com.au/2025/28/neur...

A Call for Reckoning and Reform in Interventional Pain Medicine and Neuromodulation Research www.tandfonline.com/doi/full/10....

Delighted that the editors of 15 Pain and Anaesthesiology have chosen to endorse and amplify the ENTRUST-PE framework. More info here: www.linkedin.com/pulse/entrus... @iasp.bsky.social @efic.bsky.social @britishpainsoc.bsky.social @ukrio.bsky.social @coarassessment.bsky.social

Editorial: The editors-in-chief from @thejournalofpain.bsky.social & other pain/anesthesia journals come together to align and strengthen initiatives to enhance research integrity, trust, and impact across our field. Full: doi.org/10.1016/j.jp...

#PAIN joins with other editors of pain-related journals to affirm our editorial commitment to trust and integrity in science. Read our joint statement at bit.ly/4lj3b3b

Webinar Alert! Optimising Openness and Transparency in Pain Research. Brought to you by @iasp.bsky.social MESISIG Worked examples from preclinical, clinical and qualitative research. Register now! perc.iasp-pain.org/products/opt... 5 August 2025 at 6:00 a.m. ET

Have you wanted to understand what is meant by “trustworthy” research? Attend this #webinar where @davidhosch.bsky.social, @neiloconnell.bsky.social, @jdwilko.bsky.social, @nadiasoliman.bsky.social, @lesleyuttley.bsky.social, and more outline how to produce reliable evidence bit.ly/44GBtGP

Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research journals.lww.com/pain/fulltex...

There is no scientific concept of "real world" data or evidence - there is nothing about this terminology that can't be more accurately and honestly conveyed using other accepted methodological terms.

Can we trust research? The ENTRUST-PE framework conceptualises the construct ‘trustworthiness’ of research to be supported by 7 core values. From: Editorial commitment to trust and integrity in science: implications for pain and anaesthesiology research #AnSky #MedSky doi.org/10.1111/anae...

Curious about trust in trials? FREE webinar: 21 July, 3pm UK, exploring what makes research trustworthy. Hosted by @iasp.bsky.social PRF & supported by the @jclinepi.bsky.social 👥 Speakers are leading trust and integrity researchers and journal editors. 💬 Plus live Q&A! shorturl.at/FEeMz

Douglas Adams absolutely nailing the uncanny valley of algorithmic recommendations years before they actually happened.

If you'd like a preview of INSPECT-SR, well here it is. But it is clear we need a comprehensive (and evolving) guidance document so that people use it properly. We are drafting v1.0 of that to accompany publication. Fingers crossed, we can share the preprint next month! tinyurl.com/cv9muuc4

Check out this thread on the excellent work @jdwilko.bsky.social is doing to develop tools to assess trustworthiness of clinical trials

‼️HOT OFF THE PRESS‼️ ⭐Updated Responsible AI use in Evidence Synthesis (RAISE) 3-paper collection on OSF: osf.io/fwaud/files/... ⭐ Now includes: 1️⃣Recommendations for practice for the main roles in the ecosystem 2️⃣ Guidance on building & evaluating AI tools 3️⃣Guidance on selecting & using AI tools

Authors, editors, reviewers, and other potential users should use CONSORT 2025 when writing and evaluating manuscripts of randomized trials to ensure that trial reports are clear and transparent. Learn more in this Special Communication. https://ja.ma/3TlnKQe

"Most research[...]is publicly funded, with researchers providing this content, and peer review and editorial services to publishers, largely free of charge, while at the same time being charged to read and publish[...]This situation has now reached the point where this is financially unsustainable"

Good Science xkcd.com/3101/

WONKHE has reviewed yesterday's REF2029 guidance on Contributions to Knowledge and Understanding (CKU), aka Outputs plus (or, Outputs minus, depending on one's views).

Where are the harms? Underreporting of adverse events in clinical trials investigating targeted therapy for endocrine and metabolic disorders: an observational study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Enhancing the trustworthiness of pain research: A call to action. - The Journal of Pain www.jpain.org/article/S152... To read by @neiloconnell.bsky.social

I think about this comic at least once a week

From the archives on this www.iasp-pain.org/publications...

‘Wow, this treatment was no better than placebo – because the placebo was so effective!’ It’s such a shame the term ‘placebo effect’ is so widely known and used. There are fundamental challenges with identifying it and most of the claims don’t even try. It’s just change-from-baseline every time.

I love this quote about the #Reproducibility #preprint from Brazil: “It was like trying to turn dozens of garage bands...into an orchestra,” says project coordinator Olavo Bohrer Amaral Issues raised: * Limits in experimental design * Poor documentation of methods www.nature.com/articles/d41...

If you were wondering what Scooby Doo is in French, it's Scoubidou.

4pm today in Salon Pasteur. See you there! #EFIC2025

“These are my conflicts of interest”

Coming to @efic.bsky.social Congress in Lyon from 24-26 April 2025? Don't miss pour workshop "Improving Trust And Quality In Pain Research: Recommendations From Three International Networks". 3:30pm CET Fri 25th April! See you there?

Just published by Ryan et al. Pain was present for 24% to 89% of adults with cerebral palsy (across studies) with prevalence of chronic pain ranging from 75 to 78%. Communication function, sex, and age were prognostic factors for pain prevalence. onlinelibrary.wiley.com/doi/full/10....

How much misconduct should there be in research? | BPS https://www.bps.org.uk/psychologist/how-much-misconduct-should-there-be-research Research misconduct reports at UK universities are very rare. Marcus Munafo looks at the evidence and concludes that this means one of two things...

Improving how we approach informing people about the potential risks and benefits of trial interventions. trialsjournal.biomedcentral.com/articles/10....

The World Conference on Research Integrity #WCRI, in Vancouver on May 3-6 2026, is now accepting proposals for pre-conference workshops, plenary sessions, symposia, and focus tracks. Due on April 14th. Key conference themes: • Artificial Intelligence • Research Security • Indigenous Perspectives

The UKRI has published a new draft research data policy. The policy will update and streamline UKRI's expectations for sharing and managing research data and other digital objects, such as software and code. Feedback on the draft can be made here engagementhub.ukri.org/ukri-openres...