Now might be a good time to protect your data if you’ve used this service. www.bbc.com/news/article...

ICYMI: New online! Beyond the black box with biologically informed neural networks

We're hiring Pioneer Fellow Postdocs!! Join us at the Pioneer Centre for SMARTbiomed to develop innovative methods in epidemiology, biostatistics, and statistical genetics, working with big biomedical data. international.au.dk/about/profil... #StatGen #Epi #Postdoc #SMARTbiomed

📢 New #FederatedEGA paper out: "The Federated European Genome–Phenome Archive as a global network for sharing human genomics data" 📍 Published in Nature Genetics 🔗 www.nature.com/articles/s41...

📣📣Genomic data sharing: you don’t know what you’ve got (till it’s gone) www.nature.com/articles/s41... A comment @natrevgenet.bsky.social from @katholt.bsky.social and me

New study from the @pgcgenetics.bsky.social: Multi-ancestry GWAS of MDD in over half a million cases and 4 million controls. www.cell.com/cell/fulltex...

The PGC just published the largest multi-ancestry #GWAS of #BipolarDisorder, identifying 298 genetic regions linked to the condition. go.nature.com/3PJhi3W 2/5

Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease? I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵

FlexLMM: a Nextflow linear mixed model framework for GWAS https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btaf021/7954687 🧬🖥️🧪 https://github.com/birneylab/flexlmm

We're living George Orwell's 1984: IGNORANCE IS STRENGTH.

A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it. www.science.org/content/blog...

BREAKING NEWS: CDC orders mass retraction and revision of submitted research across all science and medicine journals. Banned terms must be scrubbed. Goes beyond MMWR +other CDC pubs. Applies to research already submitted to top medical journals. Take a look. open.substack.com/pub/insideme...

Corruption 101: Clear out the cops before you send in the thieves. www.washingtonpost.com/politics/202...

Heritable polygenic editing: the next frontier in genomic medicine? www.nature.com/articles/s41... Provocative but quantitative analysis from Peter Visscher, Julian Savulescu and co.

"... the forces of racism have regrouped on the borders of legitimate science and transformed themselves into a dynamic and creative citizen science movement capable of exploiting features of human genetics... human geneticists need to contend with the evolving practices of this ... movement"

Thanks to Les Treilles Fondation (www.fondationdestreilles.com) for hosting us for a wonderful retreat to discuss causal inference in genetics with Charles Assad, Brielin Brown, @judithabk6.bsky.social, Anne Rovsing, Matti Pirinen,Marie Verbanck,Xiang Zhou,Chiara Sabatti, and Sriram Sankararaman...

The dpt started a new Primer Method session! The meeting will take place every Monday for 2 months. Today we had @hu-asch.bsky.social discussing interaction effect testing in linear models. Next week @yoann.bsky.social will talk about computing, storing and querying de Bruijn Graph from k-mer!

Scientific seminars are resuming at full speed in the dpt. We'll have two great speakers in September: @florencebansept.bsky.social on Sept 26 to discuss Host-associated microbial communities, and Ahmed Elkoussy on Sept 27 to talk about single cell and spacial genomics data analysis!