@vinceconticello.bsky.social
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reposted by
cryoEM papers
4 days ago
Distinct flagellins differentially fine tune biofilm initiation via flagellar stator-associated proteins
www.biorxiv.org/content/10.64898/2025.12.30.697036v1
#cryoem
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cryoEM papers
16 days ago
Alpha-synuclein fibril structures cluster into distinct classes
pubmed.ncbi.nlm.nih.gov/41404791/
#cryoem
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reposted by
cryoEM papers
16 days ago
Capsid flexibility during Ty1 virus-like particle assembly
www.biorxiv.org/content/10.64898/2025.12.17.694965v1
#cryoem
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reposted by
Vikram Alva
22 days ago
Happy to share that our work on HLp, a bacterial histone from Leptospira perolatii, is now published in Nature Communications đ In this study, we show that HLp forms stable tetramers that wrap ~60 bp of DNA, revealing a distinct histoneâDNA organization in bacteria.
www.nature.com/articles/s41...
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reposted by
bioRxivpreprint
about 1 month ago
Type III secretion system effector evolved to be mechanically labile and initiate unfolding from the N-terminus.
https://www.biorxiv.org/content/10.64898/2025.12.03.691928v1
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reposted by
Mart Krupovic
about 1 month ago
Check out our latest paper on mirusviruses, one of the most remarkable new groups of protist viruses - extremely diverse, carry lots of spliceosomal introns (including new homing introns) and are at the evolutionary crossroads between tailed phages and herpesviruses!
www.nature.com/articles/s41...
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Widespread and intron-rich mirusviruses are predicted to reproduce in nuclei of unicellular eukaryotes - Nature Microbiology
Environmental metagenomic explorations show that Mirusviricota lineages lack essential replication and transcription genes and contain spliceosomal introns, suggesting nuclear reproduction.
https://www.nature.com/articles/s41564-025-02190-6
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reposted by
cryoEM papers
about 1 month ago
A Bundled Antiparallel Cytochrome Nanowire Structure Suggests Roles in Cell-Cell Electron Transfer and Biofilm Formation
pubmed.ncbi.nlm.nih.gov/41279714/
#cryoem
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reposted by
cryoEM papers
about 1 month ago
The Inaugural Flatiron Institute Cryo-EM Conformational Heterogeneity Challenge
pubmed.ncbi.nlm.nih.gov/41280101/
#cryoem
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reposted by
Dave Adams
about 1 month ago
Latest work from the group looking at using our functionalised dipeptides for energy storage via a micellar analogue to MOST...
www.nature.com/articles/s42...
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Functionalized azobenzenes for micellar solar thermal energy storage as a next-generation MOST system - Communications Chemistry
Molecular solar thermal energy storage (MOST) systems employ photoswitchable molecules that absorb sunlight and store energy through reversible isomerization, cyclization or other intramolecular rearr...
https://www.nature.com/articles/s42004-025-01750-5?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20251124&utm_content=10.1038/s42004-025-01750-5
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reposted by
cryoEM papers
about 1 month ago
How Sup35 monomer conformation and amyloid fibril polymorphism determine yeast strain phenotypes
pubmed.ncbi.nlm.nih.gov/41282265/
#cryoem
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add a skeleton here at some point
about 2 months ago
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reposted by
cryoEM papers
about 2 months ago
Structural insights into the atypical filament assembly of pyrin domain-containing IFI16
pubmed.ncbi.nlm.nih.gov/41193640/
#cryoem
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reposted by
Tanmay Bharat
about 2 months ago
An Asgard archaeon with internal membrane compartments Brilliant study led by
@fmacleod.bsky.social
and Andriko von KĂźgelgen. Tight collaboration with
@buzzbaum.bsky.social
and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
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reposted by
cryoEM papers
2 months ago
Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae
pubmed.ncbi.nlm.nih.gov/41174224/
#cryoem
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reposted by
Sjors Scheres
2 months ago
We are looking for a computational postdoc to work with us on new optimisation algorithms to make
#RELION
even better. Join our bubbly team at the
@mrclmb.bsky.social
in Cambridge, UK. đ¤ RTs appreciated.
mrc.tal.net/vx/appcentre...
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Quick Check Needed
https://mrc.tal.net/vx/appcentre-ext/brand-3/spa-1/candidate/so/pm/4/pl/1/opp/2737-Postdoctoral-Scientist-Structural-Studies-Dr-Sjors-Scheres-LMB-2737/en-GB
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reposted by
cryoEM papers
2 months ago
Separation of halide oxidation and substrate halogenation chemistries rationalizes site-selective vanadium dependent haloperoxidase catalysis
www.biorxiv.org/content/10.1101/2025.10.24.684477v1
#cryoem
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reposted by
cryoEM papers
2 months ago
Impurities in amyloid studies: The power of automated model building within a cautionary tale for structural biologists
pubmed.ncbi.nlm.nih.gov/41123416/
#cryoem
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This looks pretty cool and unexpected....
www.biorxiv.org/content/10.1...
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A hierarchical nickel organic framework confers high conductivity over long distances in cable bacteria
Multi-cellular cable bacteria have evolved a unique machinery that efficiently transports electrons across centimetre-scale distances. Currents flow through a parallel network of periplasmic fibres, w...
https://www.biorxiv.org/content/10.1101/2025.10.10.681601v1
3 months ago
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reposted by
Mart Krupovic
3 months ago
A nice N&V article by Mike Dyall-Smith on our recent paper (
www.nature.com/articles/s41...
):
www.nature.com/articles/s41...
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Archaeal symbioses all the way down - Nature Microbiology
Ethiopian salt lakes feature unique microbial communities with nesting layers of symbioses, where haloarchaea and their ultra-small archaeal symbionts are prey to viruses, which are in turn hijacked b...
https://www.nature.com/articles/s41564-025-02158-6
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reposted by
cryoEM papers
3 months ago
Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency
pubmed.ncbi.nlm.nih.gov/41107248/
#cryoem
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reposted by
cryoEM papers
3 months ago
Donor strand complementation and calcium ion coordination drive the chaperone-free polymerization of archaeal cannulae
pubmed.ncbi.nlm.nih.gov/41083437/
#cryoem
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Cannulae paper published in final form. Thanks to the many collaborators and to the reviewers.
@jerryknowsnothing.bsky.social
@mikesleutel.bsky.social
@vikramalva.bsky.social
rdcu.be/eKVlI
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Client Challenge
https://rdcu.be/eKVlI
3 months ago
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Molecular Microbiology | Microbiology Journal | Wiley Online Library
onlinelibrary.wiley.com/doi/10.1111/...
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Type IV PiliâAssociated Secretion of a Biofilm Matrix Protein From Clostridium perfringens That Forms Intermolecular Isopeptide Bonds
Clostridium perfringens produces and secretes a biofilm matrix protein, BsaA, which is in the same family as the Bacillus subtilis TasA matrix protein. In this report, we show that BsaA monomers, unl....
https://onlinelibrary.wiley.com/doi/10.1111/mmi.70020
3 months ago
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reposted by
cryoEM papers
3 months ago
CryoSeek identification of glycofibrils with diverse compositions and structural assemblies
www.biorxiv.org/content/10.1101/2025.09.30.679562v1
#cryoem
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reposted by
cryoEM papers
3 months ago
Absolute hand determination of glycofibrils from natural sources in cryo-EM
www.biorxiv.org/content/10.1101/2025.09.30.679555v1
#cryoem
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reposted by
Sonja-Verena Albers
3 months ago
Look at this nice cover: beautiful archaella, image made by
@sshamphavi.bsky.social
! Thanks also to Marta Rodeiguez for keeping the EM im shape in
@ottlab.bsky.social
lab! At
@biologyunifreiburg.bsky.social
at
@uni-freiburg.de
@sfb1381.bsky.social
@cibss.bsky.social
add a skeleton here at some point
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reposted by
Fabio Strati
3 months ago
Iâm thrilled to share my latest published manuscript, which summarizes my work in the exciting fields of structural biology and amyloid research. A huge thank you to
@meytallandau.bsky.social
and the team at
@landaulabcssb.bsky.social
for their shared efforts
doi.org/10.1002/advs...
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Structural and Functional Versatility of the Amyloidogenic NonâAmidated Variant of the Antimicrobial Peptide Citropin 1.3
Citropin 1.3 is an antimicrobial peptide derived from amphibians that forms amyloid structures. Here, the structural and functional properties of citropin 1.3 are characterized. Using high-resolution...
https://doi.org/10.1002/advs.202503997
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reposted by
cryoEM papers
3 months ago
Structural and Functional Versatility of the Amyloidogenic Non-Amidated Variant of the Antimicrobial Peptide Citropin 1.3
pubmed.ncbi.nlm.nih.gov/41016026/
#cryoem
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SelfâAssembly of OffâTarget Peptide Sequences: Implications for the Design of Soft Materials - Wang - Small - Wiley Online Library
onlinelibrary.wiley.com/doi/10.1002/...
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SelfâAssembly of OffâTarget Peptide Sequences: Implications for the Design of Soft Materials
For an ionic complementary peptide, both a truncated peptide and an epimerized peptide can still form gels. Mixing these peptides with the parent FEFEFKFK leads to the formation of new, but different...
https://onlinelibrary.wiley.com/doi/10.1002/smll.202507714
3 months ago
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Filamentous structure of the CotVW complex, the crust proteins of the Bacillus subtilis endospore - Journal of Biological Chemistry
www.jbc.org/article/S002...
Spore protein assemblies are pretty wild. Nice inspiration for biomaterials design.
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Filamentous structure of the CotVW complex, the crust proteins of the Bacillus subtilis endospore
The endospores of Bacillus subtilis are encased in a multilayered protective structure comprising core, cortex, inner and outer coats, and an outermost crust. Among the proteins required for crust for...
https://www.jbc.org/article/S0021-9258%2825%2902566-9/fulltext
3 months ago
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Structural basis of Pseudomonas biofilm-forming functional amyloid FapC formation | Science Advances
www.science.org/doi/10.1126/...
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Structural basis of Pseudomonas biofilm-forming functional amyloid FapC formation
The structure of FapC reveals how Pseudomonas forms biofilms via a unique β solenoid amyloid fold and dynamic assembly pathway.
https://www.science.org/doi/10.1126/sciadv.adx7829
3 months ago
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I missed the original share on this article since I was locked out of my Bluesky account due to algorithmic impotence. Hate when that happens. Really cool structure from
@jerryknowsnothing.bsky.social
and co-authors.
rdcu.be/eHQ1N
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A family of tubular pili from harmful algal bloom forming cyanobacterium Microcystis aeruginosa
Nature Communications - Ricca et al discover a new family of tubular pili in Microcystis aeruginosa, a harmful algal bloom-forming cyanobacterium. These pili are crucial for buoyancy by forming...
https://rdcu.be/eHQ1N
3 months ago
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reposted by
Sonja-Verena Albers
4 months ago
Happy to share that our story on the bacterial archaellum was published today in
@natmicrobiol.nature.com
www.nature.com/articles/s41...
Congrats to the authors:
@sshamphavi.bsky.social
@loumollat.bsky.social
@mariejoest.bsky.social
Najwa Taib and
@sgribaldo.bsky.social
add a skeleton here at some point
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