1/10 🚨Preprint! One RING to rule them all (phages)👑💍⚔️ Bacteria build giant DNA-scaffolded RNase rings (larger than the ribosome!) to shut down viral infection🧬🧵👇 biorxiv.org/content/10.6...

++ For a deeper dive into the mechanism, @arturocdr.bsky.social has a fantastic thread, including a beautiful animation of the Retron IX ring! 👇💍🔥 bsky.app/profile/artu...

Tremendous bluesky tutorial by @arturocdr.bsky.social explaining our recent paper in colab with @rafomics.bsky.social enjoy it!!!

🧬 Thrilled to share our latest @biorxiv-microbiol.bsky.social preprint! Here we find that Retron-IX build crazy supramolecular rings scaffolded by DNA molecules that sense phage infection! www.biorxiv.org/content/10.6... Read more below🧵! (1/X)

🗓️Mañana a las 16:00h "Webinar Grupo biología sintética y biotecnología molecular" coordinado por Ylenia Jabalera Ruz 🗣️Reyes Nuñez Franco - CIC bioGUNE ✍️ https://f.mtr.cool/nzsevijhwy ▶️ Síguelo en directo: https://f.mtr.cool/ltziivmvtj

JAE Intro 2026 opportunities at SBBC. 🔬3 research projects in Structural Biology and Biophysics Contact us to learn more! @olgacalvog.bsky.social @peredalab.bsky.social @monicabalsera.bsky.social #jaeintro

New preprint! 🎉 We discovered an unexpected way that the postsynaptic scaffold protein Densin-180 binds SHANK proteins. Instead of using a conventional C-terminal PDZ-binding motif, Densin-180 uses an internal PDZ-binding motif that engages the canonical SHANK3 PDZ domain. 🧵1/8

Thanks to the wonders of the modern world it is possible to read a good translation of my article following this link: www-jotdown-es.translate.goog/2025/10/pure...

En la temporada hemos hablado de las pinzas ópticas de Carlos Bustamante @ibfg.bsky.social, de atracción de talento con @tank-silvia.bsky.social @irnasa.bsky.social o de los avances frente a la leucemia con Isidro Sánchez @ciccancer.bsky.social entre otros muchos temas 🔝 go.ivoox.com/rf/176735505

Look out for Thermo Fisher at #FEBS2026 in Maastricht and a great lunchtime symposium on 7 July from Deniz Urgurlar on lowering barriers to #cryoEM enabling faster, more reproducible structure determination across #structuralbiology, #biochemistry, and #cellbiology. 👉 Register now ter.li/7dky6tca

Don't miss tomorrow's keynote by Xiaowei Zhuang. Learn how next-generation imaging techniques reveal the location and activity of individual molecules inside cells, providing new insights into the inner workings of life. #BioPhySal2026 📅 27th june, 7:00 PM 🎟️ Free admission

🧬 @ibfg.bsky.social hosted the practical sessions on optical tweezers, one of the most advanced biophysics techniques to study molecular motors at the single-molecule level. A unique experience for the participants within the framework of the international #BioPhySAL course ⚛️✨ 🧵⬇️

Time also for discovering Salamanca's heritage, with a guided visit to the Convent of San Esteban and expert commentary by Ricardo Rivero #Biophysal2026

Third day of the course. Expert-led lectures and hands-on sessions in small groups keep learning interactive and encourage discussion and direct engagement with the experts. @usaloficial.bsky.social @ibfg.bsky.social @ciccancer.bsky.social @irnasa.bsky.social #Biophysal2026

Structural Insights into Ordered Multicomponent Assemblies in Cell Junctions pubmed.ncbi.nlm.nih.gov/42334536/ #cryoem

Anyone who watched our Thermo Scientific webinar about accessing facilities with Instruct will know this is an excellent opportunity to learn structural biology first hand. Don't miss out - get your applications in now!

👩‍🔬👨‍🔬 This international meeting brings together leading names in biosciences, such as biophysicists Carlos Bustamante and Eva Nogales from the University of Berkeley, fostering a week of scientific excellence and high-level training 🚀 🔗 www.youtube.com/watch?v=AjHd...

🏛️ The second edition of #BioPhySAL turns @usaloficial.bsky.social and the @ibfg.bsky.social into a hub for cutting-edge research, strengthening its position as an international benchmark in biophysics and structural biology 🧪✨

🧬 @ibfg.bsky.social, as part of the #BioPhySAL organizing team, reinforces its key role in scientific excellence. Yesterday, its director, @olgacalvog.bsky.social, participates in the couse opening, once again placing Salamanca on the global biophysics map 🔬🌍 🔗 ibfg.usal-csic.es/en/ibfg-seco...

BioPhySAL 2026 is underway! Learn more about the course in this interview by the University of Salamanca's Communication Department (in Spanish) @usaloficial.bsky.social @csiccyl.bsky.social #Biophysal2026 youtu.be/AjHdtQwisvE?...

Opening the Second International Advanced Course on Biophysics and Structural Biology. Six exciting days ahead of lectures, practical sessions, outstanding speakers and instructors, and plenty of opportunities for discussion and networking through our social events #Biophysal2026

🏛️ El vicerrector de Investigación, los coorganizadores y la directora del @ibfg.bsky.social han inaugurado hoy la segunda edición del prestigioso curso #BioPhySAL, un encuentro que reúne a la vanguardia de la investigación internacional en biociencias. 🧬 ➡️ comunicacion.usal.es/usal-reune-c...

Fascinating talk by Taekjip Ha on fluorescence imaging of biomolecules, showing how cutting-edge techniques are helping to explore genome in 4D #Biophysal2026

Now time for the latest advances in optical tweezers and cryo-EM from industry leaders @thermofishersci.bsky.social #Impetux #Biophysal2026

Elisabeth Villa highlighted how cryo-ET is opening new avenues for understanding bacterial infection at the molecular level @thevillalab.bsky.social #Biophysal2026

Excellent insights from José M. Valpuesta into how biophysics and structural biology reveal the active and inactive states of tyrosine hydroxylase, the functional roles of flexible and disordered regions, and the contribution of chaperones to enzyme regulation #Biophysal2026

Today marks the opening of the workshop “The Structure and Workings of Molecular Machines” in Salamanca (Spain), as part of BioPhySal Salamanca 2026 at the University of Salamanca. #BioPhysal2026 #Salamanca #UniversityOfSalamanca #Biophysics #Science #Research @usaloficial.bsky.social

A great closing talk by Adam Frost on conformational switching and allostery, providing new mechanistic perspectives on how molecular complexes transmit information through dynamic structural changes @altoslabs.bsky.social #Biophysal2026

Excellent talk by Eva Nogales on intracellular transport, showing how PTMs, protein recruitment, and macromolecular complexes shape protein interactions and cellular traffic #Biophysal2026

Excellent presentation by Fernando Moreno-Herrero on replisome dynamics, showing how AFM, optical tweezers, and magnetic tweezers provide complementary insights into the molecular mechanisms of DNA replication #Biophysal2026

Inspiring talk by Felix Ritort on the biochemistry and statistical physics of biomolecules, connecting heat capacities with single-molecule measurements using optical tweezers #Biophysal2026

Starting! Workshop "The Structure and Workings of Molecular Machines", Salamanca (Spain). @usaloficial.bsky.social @csiccyl.bsky.social

Great talk by Carlos Bustamante on protein folding using optical tweezers. Really interesting to see how single-molecule force spectroscopy can uncover foldon-mediated folding pathways #Biophysal2026

The countdown is on! Soon, the International Symposium on The Structure and Workings of Molecular Machines kicks off. 📅June 22, 2026 Followed by the Second Salamanca International Advanced Biophysics and Structural Biology Course 📆 June 23–28 📍 CIE–USAL @usaloficial.bsky.social #biophysal2026

Come along to hear about how to access cutting-edge cryo-EM services through Instruct-ERIC!

Today at 1 PM BST - there's still time to register! ter.li/zvs2nt2f

Join Thermo Fisher Scientific and the RMS tomorrow (18 June) at 1pm (BST) for a *FREE* informative webinar exploring how Instruct-ERIC facilities can support your research. Register now: https://ow.ly/FBOt50ZcJH5

Xiaowei Zhuang (Harvard University & HHMI) will deliver a special public lecture at #BioPhysal2026. 📅 June 27 | 19:00 📍 Salamanca 🎟️ Free admission, open to everyone. @usaloficial.bsky.social @csiccyl.bsky.social #biophysal2026

Thinking about trying cryoEM? Thermo Fisher Scientific is partnering with RMS to host a webinar on accessing cryoEM facilities with Instruct-ERIC on June 18 at 1 PM BST, and it’s a great chance to see how this works in practice. ter.li/zvs2nt2f #cryoEM #structuralbiology #lifesciences #research

Join Thermo Fisher Scientific and the RMS on June 18 at 1pm BST for a *FREE* informative webinar exploring how Instruct-ERIC facilities can support your research. Register now: https://ow.ly/skmZ50ZbL05

🧬 BioPhySAL 2026: La vanguardia de la Biofísica regresa a la USAL Del 23 al 28 de junio, II International Advanced Biophysics and Structural Biology Course en la USAL . 🌟 Un día antes, el 22 de junio, tendrá lugar el simposio "THE STRUCTURE AND WORKINGS OF MOLECULAR MACHINES". 🔗 biophysal.org

Holaa a todos❗️❗️ Nos complace anunciar que estaremos presentes en el evento satélite del uropean South Atlantic Biophysics (ESAB) Congress 2026.🤩 Con muchas ganas de veros allí! Programa👇

Pan-cancer atlas of ITGA6 unveils its multifaceted oncogenic roles and therapeutic potential in uveal melanoma link.springer.com/article/10.1...

Back in the lab with lots of energy and ideas after #Machinesongenes ⚙️🧬 @biochemsoc.bsky.social in beautiful Crete 🇬🇷 🐈 Besides the amazing science, it was wonderful to meet so many friends. A special highlight was this Passmore-lab mini-reunion:

New preprint We identify a conserved intramolecular interaction in KANK proteins. We show that the KANK KN domain contains separable functional modules: the LD motif mediates talin binding, while residues 60-68 mediate interaction with the KANK ankyrin repeat domain doi.org/10.64898/202...

Please share: we are looking for an experienced scientist to join the team of NeCEN, the Dutch facility for advanced cryo-electron microscopy here in Leiden. Detailed information about the position is available here: careers.universiteitleiden.nl/job/Cryo-EM-...

🔎 Cryo EM Scientist (IBL/NeCEN) 📍The Netherlands Centre for Electron Nanoscopy (NeCEN), @unileiden.bsky.social , Netherlands 🔗 instruct-eric.org/jobs/cryo-em...

Cryo-EM: the revolution continues doi.org/10.1107/S205...

RING1 is an Integrin α5 E3 ubiquitin ligase and inhibits esophageal squamous cell carcinoma cell migration and metastasis www.sciencedirect.com/science/arti...

🔬"International Symposium on The Structure and Workings of Molecular Machines" 🗓️ June 22, 2026 📍 Centro Internacional del Español (CIE–USAL), Salamanca, Spain ✍️ Registration is free and open until June 10 👩‍🔬 With #IRNASA‑CSIC 🔗 More info: biophysal.org/symposium/