I am delighted to introduce our new Centre of Excellence in Immune-Endothelial Interfaces (IMMENs) funded by the Research Council of Finland. www.helsinki.fi/en/researchg... I will be recruiting two postdocs early next year. One image analyst and one biologist interested in working on lymphatics!

Talin didn’t evolve for integrins... integrins evolved for talin 🤯 pN force coupling via talin is ancient, conserved from amoebae to humans; signaling came later. Read this amazing paper here 👇🏽 www.nature.com/articles/s41...

🚨ATENCIÓN🚨 Abrimos la convocatoria al premio JI-SBE a la mejor tesis de Biofísica de 2025. Si has defendido tu tesis en 2025 y es del ámbito de la biofísica, esta es tu oportunidad‼️ Consulta las bases del premio para más información: sbe.es/wp-content/u...

New interview alert! We had a chat with Mike Cianfrocco, Scott Stagg and Jan-Hannes Schäfer about their CryoSift tool – details in the thread. www.youtube.com/watch?v=ROlc...

Calling researchers in Spain! Don't miss out on the Instruct-ES Workshop, the first meeting of the expanded Spanish Centre in Instruct-ERIC Find out all about the technologies and latest research taking place at Instruct Centre Spain - register here 👇 instruct-eric.org/events/integ...

🚀 Update Alert The new PDBe-KB Ligand pages are live with a cleaner layout, intuitive tabs, and a brand-new onboarding tour to help you get started. Explore here 👉 pdbe.org/chem/STI

At 26, during the Reign of Terror in France, Jean-Baptiste Joseph Fourier narrowly avoided the guillotine. A decade later, he made a discovery that changed mathematics forever. www.quantamagazine.org/what-is-the-...

🚀 OPEN PhD POSITIONS in #SyntheticBiology! Join #SYNBIO-CSIC, an EU-funded doctoral programme by CSIC: ✔ 20 positions ✔ Cutting-edge research in #EngineeringBiology ✔ Interdisciplinary training for future leaders ➡️https://lifehub.csic.es/synbio-cofund/ #MSCACOFUND #SYNBIO

I just published: ERC-Plus: jackpot science or missed chance to fix academia? My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building. medium.com/p/erc-plus-j...

Checking out the most famous steps in the history of science at night

Hemidesmosomes regulate epidermal differentiation during embryogenesis www.biorxiv.org/content/10.1...

Completely wrong direction imo. It would be better and more efficient to increase funding rates of existing schemes funding more of the already fundable, great ideas for projects that are out there instead of yet another call with, most probably, less than 10% success rate.

Your periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.

🎤 Entrevista completa sobre el Proyecto MicroMundo🦠, desarrollado en el IBFG, con nuestros investigadores🧑‍🔬 Beatriz Santos y Ramón Santamaría para La 8 Salamanca📺 Ya disponible 👉 www.facebook.com/share/v/1GPc...

#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software ✅ Free 🔓 Open Source 🧬 More cloning methods than SnapGene 🤖 Can be automated with python 👨‍🔬 Built by a researcher — for researchers! 👉 Check it out at opencloning.org

Optogenetic control of mechanotransduction based on light-induced homodimerization of talin url: journals.biologists.com/jcs/article-...

I am pleased to announce the release of ProteinDJ v2! This is a major update that integrates BindCraft into the pipeline as an alternative to RFdiffusion for binder generation. You can try it out here: github.com/PapenfussLab/proteindj #ProteinDJ #BindCraft #ProteinDesign @wehi-research.bsky.social

Compartimos la información de los tres eventos que tenemos programados para el viernes 28. Seminario científico del @ciccancer.bsky.social (@usaloficial.bsky.social - @csic.es) de 10-11 horas: www.cicancer.org/press-room/c...

External seminar at the IBFG! 📢 Talk by Dr. Héctor García-Seisdedos - @ibmb-csic.bsky.social (Barcelona, Spain) 🥼 🔬Topic: Infinite assembly of folded proteins 📍 IBFG Auditorium, Salamanca 🗓️ Nov 28, 2025 – 12:00 PM

"Como pasa con mucho de lo que rodea a la ciencia en España, el nombre no es muy conocido en nuestros lares. La única forma en la que un científico salta al candelero es cuando le dan algún premio, se implica en un escándalo o fallece." elpais.com/ciencia/2025...

Excited to share our new preprint in collaboration with Ahmet Yildiz's lab. Check out how our team uncovers a novel binding footprint and motor regulation mechanism for MAP9 Congrats to Burak Cetin and @aryantaheri.bsky.social www.biorxiv.org/content/10.1...

On #EuropeAntibioticAwarenessDay, we highlight the great and impactful work done in structural biology on managing and combatting antibiotic resistance, including work from Markus Weingarth and team at @utrechtuniversity.bsky.social through Instruct-ERIC! instruct-eric.org/scientifichi...

2/ For full step-by-step instructions, check out our newly published @cp-starprotocols.bsky.social article: star-protocols.cell.com/protocols/4574 Below is a brief overview of the 5 programs included in the suite.👇

1/ With jamdock-suite, you can automate every major step of virtual screening in a local environment: 🔹 Compound library generation 🔹 Receptor preparation 🔹 Vina docking 🔹 Resuming interrupted runs 🔹 Ranking and analyzing hits 💻 Works on Windows 10/11, Linux, and macOS.

🚀 Interested in large-scale virtual screening using molecular docking? Meet jamdock-suite: github.com/jamanso/jamd... a free toolkit that automates the entire workflow including compound library generation and docking analysis. 🧵

Protocol for an automated virtual screening pipeline including library generation and docking evaluation #protocol #starprotocols #cellpress

Thank you so much for the opportunity to attend your talk at the IBFG 🙌. It was truly inspiring! ✨👏 @palconh.bsky.social

Instruct-ES Workshop, Integrative Structural Biology in the new Instruct-ES Center Madrid – January 29-30, 2026, at the IQF Blas Cabrera (CSIC) @iqf-csic.bsky.social @instruct-eric.bsky.social instruct-eric.es/2025/10/10/2... #NMRchat 🧲

Very grateful to the Danish Cancer Society and our MBG colleagues for their support! This grant will enable us to expand our research scope and grow our team. mbg.au.dk/en/news-and-...

👉 Don’t miss this opportunity to explore how cells detect and repair dangerous DNA lesions through the Fanconi anaemia pathway and what cutting-edge imaging is revealing about the molecular mechanisms that safeguard our genome. #DNARepair #Genome #FanconiAnaemia #CancerResearch

Extraordinary Seminar at the IBFG! 📢 Talk by Dr. Pablo Alcón - Aarhus University (Aarhus, Denmark) 🔬Topic: Understanding DNA Repair: Visualizing Tumour Suppressors in Action 🗓 Nov 14, 2025 – 12:00 PM 📍 IBFG Auditorium, Salamanca

🧠 Fully funded 4-year PhD studentship 🧠 Please repost BBSRC NWD project with @parikki.bsky.social and @iamabyron.bsky.social Come join us to look at how mechanical and oxidative stress signalling pathways converge on the synaptic scaffold protein talin. www.findaphd.com/phds/project...

Happy to share that our new paper is now available online @irnasa.bsky.social @usaloficial.bsky.social @unizar.es @uahes.bsky.social t.co/daOjT5HjC2

Excellent #postdoc opportunity available in @sjorsscheres.bsky.social’ group, working on new image processing algorithms for #cryoEM structure determination in their #RELION open-source software. www.nature.com/naturecareer... Apply by 25 NOV #PostdocJobs #ScienceJobs

Many thanks to the folks at the San Diego Supercomputer Center for highlighting our project!

🌟Aprobada la convocatoria de tramitación anticipada de ayudas a “Proyectos de Generación de Conocimiento” 2025 (#PID2025) 💵700 M€ (+25 M€ que 2024) ➡️Solicitudes 20 nov- 16 de dic 2025 📹Webinario: 18 de nov | 10:30 h. zoom.us/j/99421301250 www.aei.gob.es/convocatoria...

The Dutch Research Council (NWO) announced large investments in 11 (inter)national research infrastructures this week, and we are very happy that includes investments in our electron microscopy and mass spectrometry facilities, through projects EMPower and BioBeyond-NL: www.nwo.nl/en/news/nati...

Thrilled, and admittedly relieved, to see this major investment in Dutch #cryoEM become reality! 🇳🇱🔬 Honoured to be a co-applicant on this national initiative and very excited for the opportunity to advance our work in cellular structural virology! 🦠 www.uu.nl/en/news/33-m...

AI in Protein Design: Hype vs. Reality Explained by David Baker In this GEN interview, he emphasizes that designing new proteins from scratch is now a reality. Whether AI transforms medicine will require improving our understanding of biology's complexity

Erice Structural Biology Course 2026 (29 May–6 Jun): apply! Train in Cryo-EM, Cryo-ET & ML to study macromolecular assemblies in cells. Hands-on + theory for next-gen structural cell biology. 🔗 erice2026.azuleon.org/application.... #CryoEM #CryoET #MachineLearning #StructuralBiology #CellBiology

📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu

Vinculin is a simple adapter protein right? Wrong! That’s been the prevailing view for the 46 years since it was discovered. Here we provide a new paradigm and show that vinculin is a complex mechanosensor itself, containing 6 binary switch domains. www.science.org/doi/10.1126/...

Very happy @roman-bushuiev.bsky.social and I joined the amazing team led by @hannes-stark.bsky.social to work on BoltzGen, a generative model for binder design based on Boltz-2. Excited what it will enable!

We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated. mrc.tal.net/vx/appcentre...

OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇

Ayer se entregaron los Premios Alumni USAL. Muchas felicidades a los galardonados. En particular a Óscar, Sofia, Javier y Alba del @ciccancer.bsky.social

*Fully funded 4-year PhD studentship available* This MRC DiMeN DTP funded project will look at the direct interactions between talin and the hypoxic response machinery to define the protective mechanisms at play in cells that protect against oxygen depletion www.findaphd.com/phds/project...

Finally out in print! Long time project with @olexandr.bsky.social and the PHENIX group. Refinement of X-ray and CryoEM structures, using Machine Learned Potentials as the back end to help fitting. This fulfills the old dream of doing QM refinement, but very very cheap www.nature.com/articles/s41...