MEPGT
@mepgt.bsky.social
📤 69
📥 184
📝 15
PhD student in Uppsala University and Zhejiang University
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MEPGT
Daniel Ortiz-Barrientos
1 day ago
Excited to share our new paper in @GeneticsGSA ! We developed "Retriever," a novel method that enables high-quality genotype imputation in non-model organisms. 🧬 Congratulations to Charles on his first PhD paper! Paper:
doi.org/10.1093/gene...
A thread 🧵👇
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Chimeric Reference Panels for Genomic Imputation
Abstract. Despite transformative advances in genomic technologies, missing data remains a fundamental constraint that limits the full potential of genomic
https://doi.org/10.1093/genetics/iyaf212
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Jenn Coughlan
7 days ago
I'm so proud of this work!!! It was an incredible amount of effort that started when I was trapped in a greenhouse during the pandemic and is only now seeing the light of day. Kudos to Megan, Hagar, & Pia! We'd love to hear your thoughts!
www.biorxiv.org/content/10.1...
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Introgression and Parental Conflict Underlie Repeated Occurrences of Postzygotic Isolation
Postzygotic reproductive isolation is often thought to accumulate as a byproduct of neutral divergence. Yet, it frequently evolves rapidly, in line with non-neutral evolution. A major driver of intrin...
https://www.biorxiv.org/content/10.1101/2025.08.12.669975v2.full.pdf+html
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Alessio Capobianco
8 days ago
I am extremely happy to see that our review on fossil tip-dating is out in early view in Systematic Biology! A huge thanks to all the authors of this massive project (
@heckeberg.bsky.social
,
@basantakhakurel.bsky.social
, Gustavo Darlim, and
@hoehna.bsky.social
)!
academic.oup.com/sysbio/advan...
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Cell - a Cell Press journal
11 days ago
Now online! Reference genome choice compromises population genetic analyses
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Reference genome choice compromises population genetic analyses
Using a species-specific reference genome significantly improves the accuracy of population genetic analyses, as exemplified by mapping gray fox sequence data to genomes of several canid species. Mapping to a conspecific genome provides more reliable estimates of genetic variation, diversity, and evolutionary history.
http://dlvr.it/TNDCmx
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marilou boddé
15 days ago
Our paper Genomic diversity of the African malaria vector Anopheles funestus was published in Science today! It features inversions, selection in action, museum specimens and putative new ecotypes.
doi.org/10.1126/scie...
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Quaternary Habitat Fluctuations and Demographic Dynamics in Turtles Inferred From Environmental Niche Modelling and Whole Genome Data
doi.org/10.1111/1755...
18 days ago
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Persistent Genomic Erosion in Whooping Cranes Despite Demographic Recovery
doi.org/10.1111/mec....
18 days ago
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Characterisation of the Historic Demographic Decline of the British European Polecat Population
doi.org/10.1111/mec....
18 days ago
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Dr. Stepfanie Aguillon 😷
21 days ago
The first Aguillon Lab paper is officially out in early view at Evolution!! Led by postdoc
@devonderaad.bsky.social
, we’ve explored the hybrid zone between black-headed and rose-breasted grosbeaks in the Great Plains.
#ornithology
#hybridization
#speciation
#evolution
doi.org/10.1093/evol...
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Camille Roux
21 days ago
Hybridization and introgression are major evolutionary processes. Since the 1940s, the prevailing view has been that they shape plants far more than animals. In our new study (
www.science.org/doi/10.1126/...
), we find the opposite: animals exchange genes more, and for longer, than plants
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Charlotte Wright
22 days ago
How many chromosomes can an animal have? In our paper out now in
@currentbiology.bsky.social
we show that the Atlas blue butterfly has 229 chromosome pairs- the highest in diploid Metazoa! These arose by rapid autosome fragmentation while sex chromosomes stayed intact.
www.cell.com/current-biol...
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Constraints on chromosome evolution revealed by the 229 chromosome pairs of the Atlas blue butterfly
The genome of the Atlas blue butterfly contains ten times more chromosomes than most butterflies, and more than any other known diploid animal. Wright et al. show that this extraordinary karyotype is ...
https://tinyurl.com/atlasbluebutterfly
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Daniel Ortiz-Barrientos
about 1 month ago
We’ve just published a paper on Senecio showing that ecological speciation and mutation-order speciation can act together rather than as an either/or. Congratulations, Maddie James and MC Melo!
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Nikunj Goel
about 1 month ago
My first methods paper from postdoc—How to identify genomic adaptation to climate using a mechanistic model of evolution.
@methodsinecoevol.bsky.social
besjournals.onlinelibrary.wiley.com/doi/10.1111/...
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Identifying genomic adaptation to local climate using a mechanistic evolutionary model
Identifying genomic adaptation is key to understanding species' evolutionary responses to environmental changes. However, current methods to identify adaptive variation have two major limitations....
https://besjournals.onlinelibrary.wiley.com/doi/10.1111/2041-210X.70117
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Clàudia Fontserè
about 1 month ago
This is now published at
#MolecularEcology
onlinelibrary.wiley.com/doi/10.1111/...
Check it out!
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Anton Suvorov
about 1 month ago
My very first post on here. I am stoked to share lab's latest paper led by
@ethantolman.bsky.social
. Ethan developed a highly scalable pipeline to differentiate between various gene flow models, including ghost introgression in phylogenomic datasets. Check it out!
www.biorxiv.org/content/10.1...
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GhostParser: A highly scalable phylogenomic approach for the identification of ghost introgression
A growing body of empirical research shows that interspecific gene flow is a widespread biological force that shapes evolutionary histories across the Tree of Life. Computational approaches designed t...
https://www.biorxiv.org/content/10.1101/2025.08.21.671585v1
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I love conifers.
about 1 month ago
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bioRxiv Bioinfo
about 1 month ago
GhostParser: A highly scalable phylogenomic approach for the identification of ghost introgression
https://www.biorxiv.org/content/10.1101/2025.08.21.671585v1
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Marty Kardos
about 1 month ago
www.pnas.org/doi/full/10....
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Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake | PNAS
Small and fragmented populations are at high risk of local extinction, in part because of elevated inbreeding and subsequent inbreeding depression....
https://www.pnas.org/doi/full/10.1073/pnas.2501745122
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Fernando Villanea
about 1 month ago
Our paper on the evolution of MUC19 in humans, Neanderthals, and Denisovans is finally out today in Science! This has been a six-year effort by 13 authors to weave together 3 separate but related evolutionary stories around this one gene (more on thread 🧵).
www.science.org/doi/10.1126/...
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The MUC19 gene: An evolutionary history of recurrent introgression and natural selection
We study the gene MUC19, for which some modern humans carry a Denisovan-like haplotype. MUC19 is a mucin, a glycoprotein that forms gels with various biological functions. We find diagnostic variants ...
https://www.science.org/doi/10.1126/science.adl0882
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Aryn Wilder
about 1 month ago
Excited to share our new paper on genetic rescue in the Pacific pocket mouse! To conserve this endangered species, we sought to understand whether small populations at risk of outbreeding depression are better managed in isolation or with gene flow.
@science.org
www.science.org/doi/10.1126/...
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Fitness benefits of genetic rescue despite chromosomal differences in an endangered pocket mouse
Two-thirds of Earth’s species have undergone population declines, leaving many vulnerable to genomic erosion and inbreeding depression. Genetic rescue can boost the fitness of small populations, but p...
https://www.science.org/doi/10.1126/science.adn4666
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Thibault (Tibo) Leroy
about 1 month ago
Le mariage des roses d'Occident et d'Orient au XIXe siècle: pour le meilleur et pour le pire?
theconversation.com/comment-le-c...
Petit article de vulgarisation pour The Conversation de nos recherches récentes sur l'histoire de la sélection des rosiers au XIXe! Alors... tout serait-il si rose? 🌹🧬❤️
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Sam Yeaman
about 1 month ago
I'm looking to recruit a PhD student to study patterns of local adaptation and introgression across the spruce hybrid zone in the Rockies near Calgary. Projects can include field work, bioinformatics, pop gen theory, or comparison to plant/ conifer species
yeamanlab.weebly.com/uploads/5/7/...
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Julio Rozas
4 months ago
How did evolution drive massive genome contraction during oceanic island colonization? A new paper from our lab.
www.biorxiv.org/content/10.1...
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Andreas Wallberg
about 2 months ago
I am announcing an open PhD position involving bioinformatics, genomics and machine learning to work on functional prediction of adaptive genetic variation in krill and herring!
www.uu.se/en/about-uu/...
Going to
#ESEB2025
@eseb.bsky.social
? Find me in poster session 1 for a chat!
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Fantastic story!
mp.weixin.qq.com/s/ahXTkHyts1...
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Nat Ecol Evol | 兰州大学刘建全教授与昆明植物所孙航院士等人合作揭秘高山之巅的动植物生死博弈
紫堇的每一片灰色叶片都在诉说着生存的智慧,流石滩上每只绢蝶都映照着自然选择的锋芒。保护这些高山精灵,不仅是保存基因库,更是守护一个持续运转了百万年的演化实验室
https://mp.weixin.qq.com/s/ahXTkHyts1f-LN30aGXHFw
about 2 months ago
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Ryan Gutenkunst
about 2 months ago
Our manuscript describing the first Genomic History Inference Strategies Tournament is now on bioRxiv! Enjoy reading about the 2024 competition as you prepare your entries for the 2025 competition!
ghi.st
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GHIST 2024: The 1st Genomic History Inference Strategies Tournament
Evaluating population genetic inference methods is challenging due to the complexity of evolutionary histories, potential model misspecification, and unconscious biases in self-assessment. The Genomic...
https://doi.org/10.1101/2025.08.05.668560
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Molly Schumer
about 2 months ago
Our review on the last decade+ of hybrid incompatibility research is now out!
www.sciencedirect.com/science/arti...
Original thread here:
bsky.app/profile/moll...
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@mollyschumer.bsky.social
Very exciting review!!!👍👏The molecular evolutionary basis of species formation revisited.
www.cell.com/trends/genet...
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The molecular evolutionary basis of species formation revisited
How do new species arise? This is among the most fundamental questions in evolutionary biology. The first genetic model for how reproductive barriers lead to the origin of new species was proposed nea...
https://www.cell.com/trends/genetics/fulltext/S0168-9525(25)00167-2#f0005
about 2 months ago
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闵娅(Min Ya; Minya) PhD
about 2 months ago
I’m proud to present the main work from my postdoc, 3+ years in making from scratch, my ultimate
#MimulusPropaganda
up till now: The Moment That Symmetry Breaks.
#plantscience
#development
#imaging
#microscopy
🧪🌸🔬 w. Captain Yaowu &
@biancatash.bsky.social
www.biorxiv.org/content/10.1...
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Chris Kyriazis
about 2 months ago
I am thrilled to share this paper outlining some ideas I’ve been thinking about for a little while on a simple but powerful approach for predicting risk of inbreeding depression from long runs of homozygosity and non-ROH heterozygosity. 1/n
@klohmueller.bsky.social
doi.org/10.1016/j.tr...
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Leon Hilgers
2 months ago
You link
#phenotype
🦜 to
#genotype
🧬 with
#comparative
#genomics
💻? This
#review
is for you 📜:
authors.elsevier.com/sd/article/S...
We review new
#methods
, remaining
#challenges
and
#future
directions and highlight recent key studies. Thanks
@hillermich.bsky.social
! Please share! 🙂
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Joana Meier
2 months ago
Our paper, led by Eva van der Heijden, shows the work of an international team combining phylogenomics, hybridisation tests, population and comparative genomics and pheromone analyses to resolve the taxonomy and evolution of two rapid radiations of glasswing butterflies.
www.pnas.org/doi/10.1073/...
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PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
https://www.pnas.org/doi/10.1073/pnas.2410939122
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Pablo Garcia-Diaz
2 months ago
Empirical evidence of widespread exaggeration bias and selective reporting in ecology 🌎🌐🧪
www.nature.com/articles/s41...
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Empirical evidence of widespread exaggeration bias and selective reporting in ecology - Nature Ecology & Evolution
Analysing >18,000 effect sizes from recent ecology studies published in five leading journals, the authors identify widespread under-powered designs, exaggeration bias, selective reporting and few ...
https://www.nature.com/articles/s41559-023-02144-3
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Emily Josephs
4 months ago
Hey, Miles'
@milesroberts.bsky.social
beautiful paper showing that sequence diversity missed by standard methods contributes to Lewontin's paradox is officially published in
@evolletters.bsky.social
.
academic.oup.com/evlett/advan...
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k-mer-based diversity scales with population size proxies more than nucleotide diversity in a meta-analysis of 98 plant species
Abstract. A key prediction of neutral theory is that the level of genetic diversity in a population should scale with population size. However, as was note
https://academic.oup.com/evlett/advance-article/doi/10.1093/evlett/qraf011/8161170
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Thomas Lenormand
3 months ago
Interested to know more about a new theory relating the
#evolution
of
#sexchromosomes
to the rules of
#speciation
? Check out this paper that we published with Denis Roze in the last issue of
#Science
. PDF here:
www.science.org/stoken/autho...
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A single theory for the evolution of sex chromosomes and the two rules of speciation
Sex chromosomes are involved in three major empirical patterns: (i) Y (or W) chromosomes are often nonrecombining and degenerate; (ii) heterogametic offspring (XY or ZW) from interspecific crosses are...
https://www.science.org/doi/10.1126/science.ado9032
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Felix Martinez
3 months ago
Our story about salinity tolerance in the Cape Verde islands is out in Science Advances!
@science.org
. Two independent mutations in the same gene conferred salt resistance to Arabidopsis plants! Check it out here!
www.science.org/doi/10.1126/...
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Parallel evolution of salinity tolerance in Arabidopsis thaliana accessions from Cape Verde Islands
Plants from the Cape Verde Islands evolved parallel mutations to protect from high salinity.
https://www.science.org/doi/10.1126/sciadv.adq8210
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MBE Cover: Evolutionary Genomics Unravels the Responses and Adaptation to Climate Change in a Key Alpine Forest Tree Species
academic.oup.com/mbe/article/...
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Evolutionary Genomics Unravels the Responses and Adaptation to Climate Change in a Key Alpine Forest Tree Species
Abstract. Despite widespread biodiversity loss, our understanding of how species and populations will respond to accelerated climate change remains limited
https://academic.oup.com/mbe/article/42/7/msaf116/8148825?login=false
3 months ago
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Accounting for population structure and data quality in demographic inference with linkage disequilibrium methods
www.nature.com/articles/s41...
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Accounting for population structure and data quality in demographic inference with linkage disequilibrium methods - Nature Communications
Accurate estimation of effective population size is critical for understanding population history but is often confounded by structure and data quality. Here, the authors show that GONE2 and currentNe...
https://www.nature.com/articles/s41467-025-61378-w
3 months ago
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Romina Henriques
3 months ago
🧪🧬
add a skeleton here at some point
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Nature Reviews Biodiversity
3 months ago
This article is free to access for two weeks! Download now! 👇🌎🧪
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So cool!
add a skeleton here at some point
3 months ago
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Nature Reviews Biodiversity
3 months ago
New online! The status, threats and conservation of Critically Endangered species
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The status, threats and conservation of Critically Endangered species
Nature Reviews Biodiversity, Published online: 25 June 2025; doi:10.1038/s44358-025-00059-4Species classified as Critically Endangered are at greatest risk of extinction, and their preservation and recovery are crucial to meeting global biodiversity aims. This Review assesses the geographical and taxonomic distribution of Critically Endangered species, their threats, current and required conservation actions, and strategies to facilitate effective, coordinated conservation.
https://bit.ly/3Tagoir
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mepgt.wordpress.com
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Presonal Blog
Daily updates of molecular evolution and population genomics literature and useful software tools
https://mepgt.wordpress.com
3 months ago
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Arun Durvasula
4 months ago
Our review of recent Sequentially Markovian Coalescent methods is up on arXiv:
arxiv.org/abs/2506.00692
(based on last year's
@official-smbe.bsky.social
symposium)
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Not Just $N_e$ $N_e$-more: New Applications for SMC from Ecology to Phylogenies
Genomes contain the mutational footprint of an organism's evolutionary history, shaped by diverse forces including ecological factors, selective pressures, and life history traits. The sequentially Ma...
https://arxiv.org/abs/2506.00692
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Katarina Stuart
4 months ago
New preprint out: "A Beginner’s Guide to Structural Variants in Eco-Evolutionary Population Genomics: Everything You Wanted to Know" A primer for anyone curious about digging into structural variants within their study system. Huge thank you to my brilliant co-authors!
doi.org/10.22541/au....
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A Beginner’s Guide to Structural Variants in Eco-Evolutionary Population Genomics: Everything You Wanted to Know
1. IntroductionCharacterizing genomic variation is fundamental to address many ecological and evolutionary questions. The ‘evolution’ of DNA sequencing methods over time has enabled the identification...
https://doi.org/10.22541/au.174853973.36642913/v2
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Chris Kyriazis
4 months ago
Very excited to share the first paper from my postdoc at the San Diego Zoo Wildlife Alliance on the population genomics of recovery and extinction Hawaiian honeycreepers: Paper:
doi.org/10.1016/j.cu...
Press release:
sandiegozoowildlifealliance.org/PR/hawaiian-...
@currentbiology.bsky.social
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Moi Expósito-Alonso (MOILAB)
4 months ago
Super excited to release a huge evolution project on the works for many years: Evolution experiments synchronized across climates to understand rapid adaptation Preprint:
doi.org/10.1101/2025...
All data available: www.grene-net.org/data
#MOILAB
@ucberkeleyofficial.bsky.social
@hhmi.org
🧵👇
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Congrats!
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4 months ago
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Astrid Böhne
5 months ago
Happy to share this collaborative effort on recommendations for
#genomics
of
#type
specimens
academic.oup.com/sysbio/advan...
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Type genomics: a Framework for integrating Genomic Data into Biodiversity and Taxonomic research
https://academic.oup.com/sysbio/advance-article/doi/10.1093/sysbio/syaf040/8138649
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Rike Stelkens
5 months ago
Just out in PNAS!
www.pnas.org/doi/10.1073/...
"The evolution of thermal performance curves in response to rising temperatures across the model genus yeast". Beautiful work using experimental evolution forecasting climate impacts on biodiversity by Jennifer Molinet
@jennifermolinet.bsky.social
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