The authors of this piece are anti-vax ivermectin scammers who think SARS2 was a vaccine-bioweapon made via a Fauci x PLA GOFROC collab, yet they straight up copied “proximal origin” from the title of the lab leak community’s most hated paper of all time. For their own H5N1 lab leak paper. 🤣

Regionalised vaccine manufacturing could offer a path forward for equitable vaccine access and rapid response to outbreaks. On the cover, a new Comment explores the collaboration and action required to shift to a regionalised approach. Read this & more: tinyurl.com/3dma8e9u

#IDSky #MedSky required reading: Multidrug-resistant Gram-negative bacterial infections Nenad Macesic, Anne-Catrin Uhlemann, Anton Peleg Review in @thelancet.bsky.social doi.org/10.1016/S014...

Introducing Nature Reviews Biodiversity! This Review explores the relationship between emerging infectious diseases and biodiversity loss, and how both are connected to global environmental changes in the Anthropocene. https://go.nature.com/42fzUQk 🧪

In the conversations on vaccine hesitancy we do not talk enough about the rising vaccine hesitancy among pet owners. This also presents important public health concerns that need to be addressed. This article clearly outlines some of the risks of this trend. theconversation.com/vaccine-hesi...

Whoa! When a large language of life model generates a protein equivalent to ~500 million years of evolution. @science.org science.org/doi/10.1126/...

Published Friday, the National One Health Framework to Address Zoonotic Diseases and Advance Public Health Preparedness in the U.S. The dominant word seems to be "coordinate", which, yeah, needed

Today's @washingtonpost.com editorial board piece www.washingtonpost.com/opinions/int...

Our technique for studying strain-level IgA binding in the microbiome is out now at @naturemicrobiol.bsky.social! Fascinated by IgA since Sean Spencer told me about it, here we make some fundamental discoveries about strain-level IgA dynamics in the healthy human gut (1/5) doi.org/10.1038/s415...

The Current and Future State of Vaccines for Lyme Disease ✅ Just Accepted #IDSky

💥 My 2024 Mile Marker: The inside scoop on how America lost control of the Bird Flu, opening the door for another pandemic. "We're in a terrible situation" said @angierasmussen.bsky.social 🧵Here's how we got here & how to get out @kffhealthnews.bsky.social kffhealthnews.org/news/article...

Systems Vaccinology: Navigating the Future of Personalized Immunity and Next-Generation Vaccines #IDSky

Here is a sneak peak of the new sequencing technology I have been working on together with many others. Much more to come in 2025! www.illumina.com/science/geno...

Our paper out today: “Spillover is an ecological process… While the human health issues arising from spillover events…are addressed by epidemiological and biomedical countermeasures…, the ecological aspects of spillover necessitate ecological solutions” 🧪🌏 t.co/cL4qY5Pwnk

I’m pleased to share the publication of my latest first-author manuscript. I would like to thank @mehrad-hamidian.bsky.social, Eradah Abu Sabah, and @garry-myers.bsky.social—as well as our collaborators, Patrick McGann and Francois Lebreton. @aimi-uts.bsky.social academic.oup.com/jac/article/...

#vaccine #pediatrics Today’s vaccine post will be the most famous Covid vaccine conspiracy- that they are causing a ton of cardiac deaths (TLDR, no they are not). To understand this claim requires a couple of different sources, so this will be a fairly long thread.

A new @science.org article from 30+ leading international scientists including several @jcvi.org researchers, examines the potential dangers of building ‘mirror life’ — organisms composed entirely of mirror-image biological molecules. 🧪

Wow just wow. I did not have on my bingo card an mRNA therapeutic for treating pre eclampsia. A VEGF tropic mRNA resolved maternal hypertension until pregnancy in a mouse model of the condition. Really fascinating science. 🧪 www.nature.com/articles/s41...

For those wondering why we seem to be so behind when it comes to effective mucosal vaccines against respiratory viruses, this really excellent overview from leaders in the field offers a great summary: www.nature.com/articles/s41... few additional points for those who want a bit more detail🧵:

Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. A study in Nature Microbiology presents an approach to systematically discover and understand such antibiotic relationships. https://go.nature.com/49of3Mk 🧪

And this was also clear from an unpublished paper from 2018 which showed that the closest virus to SC2 at the WIV was RaTG13 (Ra4991). As this study was prior to the pandemic there was no reason to hide anything. But the progenitor of SC2 was not there because they never had it. End of.

Have you ever wondered how knocking out every single gene in the human genome, one by one, might affect your intracellular pathogen of interest? We did, & boy was it a wild ride! Happy to share our preprint discovering the essential host genome for Cryptosporidium - www.biorxiv.org/content/10.1...

Four out of five prizes won🎖️ by AIMI students at the UTS Faculty of Science Transdisciplinary ECR Retreat Congratulations to: Lachy (best talk) Liam (runner up talk) Sophia (people’s choice talk) @arianacostas.bsky.social (best poster)

A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors www.science.org/doi/10.1126/...

There are more ways to design an mRNA than atoms in the universe, so how do you choose the best one? Our new @basemrna.bsky.social software, mRNArchitect enables you to tune expression, stability, reactogenicity and synthesisability to design more potent #mRNA drugs. www.biorxiv.org/content/10.1...

Protein degraders delivered via mRNA… www.biorxiv.org/content/10.1...

Correct. Those, including other ‘scientists’, who have made continual baseless claims about our paper, that it was ghost written, plagiarised, or we were paid off, should reflect hard on the misinformation they have spread and the hate they have sown.

mRNA-encoded transcription factor inhibitors are a rapidly emerging class of drugs. In Science Translational Medicine a team at Harvard treated retinal disease in animals by inhibiting RUNX1. Stay tuned for our forthcoming work targeting cancer transcription factors. www.science.org/doi/10.1126/...

So despite what they ‘believe’ in the intro, it turns out after 500+ pages SSCP have NOTHING to support a lab leak. Zero evidence other than feels and the misrepresentation of facts and scientists by fantasists. And buried with no discussion, black and white proof that there was no conspiracy 👇

Bactericidal antibiotics release bacterial DNA that activates TLR9, while static antibiotics do not. This can profoundly impact treatment outcome. Should clinicians consider this when choosing antibiotics to prescribe? Amazing work by Julia Gross and collaboration with Iain Fraser! rdcu.be/d1Phk

#ArchaeaSky www.nature.com/articles/s41...

AMR (Anti-Microbial Resistance) to #Antibiotics Could Surpass Cancer as Leading Cause of Death by 2050❗ While #AMR primarily involves #bacteria, viral infections and #vaccination 💉against #viruses is also a major part of a solution. #AntiMicrobialResistance www.medscape.com/viewarticle/...

I'm recruiting! I'm looking for a motivated postdoctoral scientist to join my new team at SCELSE in Singapore. The role will explore various aspects of how #eDNA is produced and utilised in #Pseudomonas aeruginosa biofilms. #Microsky #phagesky #Science ntu.wd3.myworkdayjobs.com/Careers/job/...

The CDC has released the 2025 schedule of recommended immunizations by vaccine/other agents and age group, from birth through 18 years of age. The resource is available at www.cdc.gov/vaccines/hcp... #IDSky #vaccines #immunizations #pedsID

A Vatican symposium highlighted the urgent threat of AMR and its potential to collapse modern medicine. The event called for governments, faith communities, and the public to work together to prevent a return to pre-antibiotic-era healthcare. www.ewtnvatican.com/articles/vat...

Impressive work from lab of @evamarianovoa.bsky.social Scalable and reproducible workflow of native RNA nanopore sequencing + NanoConsensus analysis finds significant rRNA modification changes in response to antibiotic stress—genuinely novel concept for AMR research www.nature.com/articles/s41...

#vaccines #pediatrics The anchoring bias is when your future conclusions depend very heavily on an initial anchoring point. This tactic was used very, very extensively with COVID vaccines on different far right social media platforms - whenever they saw a side effect, they attributed it to vaccines.

This week in @science.org Molecular basis of #mRNA delivery to the bacterial #ribosome www.science.org/doi/10.1126/...

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"Any pleasure I may take in the distinction of [being a Royal Society fellow] is diminished by the fact it is shared with someone who appears to be modelling himself on a Bond villain" www.researchprofessionalnews.com/rr-news-uk-c...

Facts matter. Science saves lives. Anti-science destroys them.

Back in 2022, there was a weird conspiracy theory published arguing that, somehow, the reverse compliment of a sequence from a Moderna plasmid ended up in SARS-CoV-2. Unsurprisingly, it turned out to be an unremarkable coincidence: www.frontiersin.org/journals/vir...

Bacterial single-cell RNA sequencing captures biofilm transcriptional heterogeneity and differential responses to immune pressure -in #NatureCommunications by Lee Korshoj and Tammy Kielian www.nature.com/articles/s41...

Be very clear what this is: a shallow attempt to bash Fauci and NIH. The reason why there is no "proven link" between NIH, EcoHealth Alliance and origin of COVID-19 is because there is no link between NIH, EcoHealth Alliance and origin of COVID-19. They've spent years on this already.

The first review article from my lab, helmed by @celiasouque.bsky.social, "From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance" is now online and open access at Annual Reviews Microbiology: www.annualreviews.org/content/jour...

Incredible graphic - the myriad of ways that bacteria defend themselves against antibiotics. 14 resistance mechanisms, summarised by Idan Yelin & Roy Kishony in Cell www.sciencedirect.com/science/arti...