Come be my colleague (& @jacquelyngill.bsky.social's and other great folks)! UMaine is hiring a Genetics Facilities Manager to lead the CORE eDNA and DNA Sequencing Labs. Hiring range is $75-85k (up $20k from previous round) fa-ewca-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

🧪 Basic science boosts the economy: "The proposed dismantling of NSF [and NIH] raises an urgent question: do these cuts actually save money or merely delay spending until the bill gets larger? The answer is clear: these cuts will cost the economy billions."

Fascinating post from @steveroyle.bsky.social on his "academic software stack". Really useful survey of software tools, databases, calendars, note taking apps, etc. a savvy lab is using. Essential reading for new PIs quantixed.org/2025/04/29/s...

A group of scholars and I had a chance to share our experiences with the MOSAIC program being terminated 🧪 www.npr.org/sections/sho...

What a great idea @sciencehomecoming.bsky.social "The idea behind Science Homecoming is that scientists across the United States get in touch with the local newspaper where they grew up and make the case for why funding science is important to those communities." www.nature.com/articles/d41...

Deep dive into 800 cancelled NIH grants. www.nature.com/articles/d41...

Corum is, of course, ON IT.

And on other news. My first contribution to science as a postdoc with @stirlingchurchman.bsky.social is out! We discuss the knowns and unknowns of post-transcriptional splicing. It was really fun to write with the great @karinechoquet

Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration. scim.ag/41zlPv4

At the #StandUpForScience rally outside the #Michigan Capitol building. Good turnout (especially with MSU on spring break) -- I'd estimate 800 to 1000 folks. Great speakers from MSU, UM, and Wayne State and representing all career stages and many fields. Lots of clear and clever homemade signs.

Getting reports of some sound problems with our Twitch livestream. Here's another stream while we sort out some technical difficulties! www.youtube.com/watch?v=eemj...

I’m thinking we should spread this news about the firings at NOAA as far and wide as possible. Like cancer research, weather forecasting seems likely to be broadly popular across the political spectrum. apnews.com/article/nati...

Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH 🧬🧪 🖥️ 🧠 www.science.org/content/arti...

As a result of Trump’s slashes to research funding, dozens of graduate programs have announced reductions and cancellations of graduate admissions slots. If you are an impacted applicant, please fill out this survey: docs.google.com/forms/d/e/1F... 🧪🧠🧬🔬🥼👩🏼‍🔬🧑‍🔬

A website has been started in response to the orders to take down references to women’s accomplishments in government offices. We are not going to let them erase us this time. womenrefusingtobeerased.org

We all know the story of Henrietta Lacks, but there are countless other examples when biomedical research advanced with a little regard for morals or ethics - often at the expense of poor, disadvantaged, or minority individuals. This book has been enlightening. A good read for current scientists.

Breaking language barriers: ‘Not being fluent in English is often viewed as being an inferior scientist’

Bioinformatics Methods for Transcriptomics -- looks like a great course https://www.coursera.org/learn/bioinformatics-methods-for-transcriptomics

To Read:

I guess I hadn't posted this yet and didn't even know it had come out-- I was interviewed for (and co-wrote w/Daniel Rabosky) a Trends in Ecology & Evolution "TrendsTalk" article on "Disability in ecology and evolution" -- www.cell.com/trends/ecolo... #DisabledInSTEM #academicchatter #academia

I’m excited to share that this manuscript is now published in Nature Genetics! 🧪🧬 🖥️ www.nature.com/articles/s41... The AdipoExpress data can be accessed here: zenodo.org/records/1384... An interactive browser of the colocalization results can be accessed here: adipose.colocus.app

The #DNADay25 Essay Contest is HERE! 🧬High school students worldwide are invited to tackle this year’s thought-provoking question: How can and should Artificial Intelligence (AI) be used in genetic testing? Submit your essay by March 5👉 www.ashg.org/dna-day/ #ASHG #HumanGenetics

Superb work by Wouter @Zouters & @OlgaPushkarev developing ChromatinHD, two scale-adaptive #machinelearning models & interpretation tools that use #scRNAseq + #scATACseq data to better understand how chromatin accessibility relates to gene expression doi.org/10.1038/s414... Happy 2025 everyone 🎆 !

This looks amazing. What a wonderful tribute!

Every cell in our body is unique. EMBL researchers have developed a statistical tool – LEMUR – to compare tissues and organisms using single-cell RNA sequencing and use it for applications in human health and fundamental biological research. #AcademicSky 🧬🧪 www.nature.com/articles/s41...

Reading now: Unveiling adipose populations linked to metabolic health in obesity by I Reinisch et al. #adipose #RNAseq #snRNAseq #SingleNucleus 🧬🖥️🧪

Isoform-level discovery, quantification and fusion analysis from single-cell and spatial long-read RNA-seq data with Bambu-Clump www.biorxiv.org/content/10.1... 🧬🖥️🧪 #Rstats 📦 github.com/GoekeLab/bam... Nextflow pipeline 🔀 github.com/GoekeLab/bam...

I see a lot of popular accounts popping up who don't use alt-text on images. Alt-text is useful for a wide variety of users. Maybe you mean to use it and forget. That happens! Fortunately you can set this particular setting to help. Three seconds and you're good.

Calling group leaders in the life sciences! We're collecting examples of successful job application materials for a career workshop for postdocs applying to academic roles. Interested in sharing your materials? Drop us a line at [email protected] & we'll send you further info.

Revealing gene function with statistical inference at single-cell resolution go.nature.com/4eMji6A #Review by Cole Trapnell

Multifunctional histone variants in genome function go.nature.com/4dDLXcI #Review by Lee H. Wong & David J. Tremethick Free to read: rdcu.be/dQO4i

Adjusting for principal components can induce collider bias in genome-wide association studies, KE Grinde et al. "we investigate the impact of LD filtering and pruning, as well as choices of the number of PCs to include in analyses, when performing GWAS in admixed populations." #GWAS #PCA

One of the biggest questions we get is when will our journals be here. We thank you for your patience. You can now follow our journals with this starter pack!

Reading now: Accurate quantification of nascent and mature RNAs from single-cell and single-nucleus RNA-seq by @delaneyksull.bsky.social @guillaumeolesan.bsky.social @pmelsted.bsky.social @lpachter.bsky.social et al. #RNAseq #scRNAseq #snRNAseq #SingleCell #SingleNucleus

🌍🧪 Want to do something different and have fun? Try Skype a Scientist! It's an amazing chance to connect with a classroom anywhere in the world 🌎 and share your journey as a scientist. 👩‍🔬 The new 2025 volunteer form is out 🥳 Let’s inspire the next generation! 💡✨ #PhDSky #AcademicSky #MedSky

📍Pinned Post: Welcome to the RNA-seq feed: bsky.app/profile/did:... Anyone can post to this feed if you mention RNA-seq, RNAseq, transcriptome, transcriptomics. blog.stephenturner.us

Advent Calendar Advent Calendar xkcd.com/3019

Visit the table of all #GWAS with #Metabolomics to read more about the latest #mQTL discoveries (updated 23 April 2024) wp.me/p6NCOp-2y

My work features prominently in a Nature editorial today. Great to see digital preservation being taken seriously. "Millions of research articles are absent from major digital archives. This worrying finding, [...] was laid bare in a study by Martin Eve" www.nature.com/articles/d41...

Reading now: High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction #scRNAseq bmcgenomics.biomedcentral.com/articles/10....

I love seeing lists of early career scientists!

Something to keep in mind... I'm happy to use English as my work language, but frustrated by how this is often a blind spot among supporters of inclusivity stuck in a US-centric view of research

4️⃣1️⃣ Olanike Kudirat Adeyemo (1970- ) 🇳🇬 #womeninSTEM First woman to become Deputy Vice-Chancellor of the University of Ibadan in Nigeria. Her research focuses on epidemiology, aquatic toxicology and public health. getjournal.org/prof-olanike...

I asked a DALL-E-based GPT to produce a graphic showing the components of adipose tissue. Most of the labels aren't even real words. #adipose #GPT #AI #WhatIsAnAdiccoyte

Okay, gang. Are we ready for a little Bluesky #PlantsGiving action? A social media tradition since 2018: counting & reporting out the number of plant species consumed during your Thursday dinner. I've got a class doing it for homework. Excited to see what they share. #iamabotanist #bisonflowers

It's my great pleasure to present the next big preprint from SheqLab! An exciting application of our O-MAP platform that I hope will transform the study of nuclear architecture. If you've ever wanted to dissect the subnuclear "neighborhood" around an individual locus, read on! (1/30)

If you are thinking about biomedical research after your undergrad but before grad school (or as a backup for your grad apps), checkout propel.ucsf.edu. We will have an info session THIS FRIDAY! Register at justice.ucsf.edu.

Interested in #singlecell and #spatial #metabolomics? Then book your calendar for December 10th! – Our online, free event will summarize major achievements of the field in 2024. #metabolism #omics #MALDI #EPFL With Giovanni D'Angelo and our #PhD students we prepared for you a fantastic lineup. 🧵 1/5

It's only right that my first post here is sharing Scotland's map of named ice gritters. You can follow where they all are in real-time. Some favourites this year: Sir David Attenbrrrrrr Stone Cold Steve Frostin Lord Coldemort You're a blizzard, Harry www.traffic.gov.scot/gritter-trac...