Awesome www.sciencedirect.com/science/arti...

With the @lindorfflarsen.bsky.social group we present our map of degrons in all human transcription factors, incl. examples of constitutive degrons in exposed regions & buried degrons that are exposed upon mutation. In addition, we show that most TADs overlap with degrons. Work led by Fia Larsen.

For my weekend reading www.biorxiv.org/content/10.1...

What happens when a modern human-specific amino acid in a neuronal RBP is introduced in a mouse? Please check if this question sounds interesting to you! So happy to see this work published. Congrats to the whole team! www.nature.com/articles/s41...

Review article for my weekend www.cell.com/action/showP...

Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41... A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work

Mechanisms of synergistic Mediator recruitment in RNA polymerase II transcription activation revealed by single-molecule fluorescence https://www.biorxiv.org/content/10.1101/2024.12.10.627625v1

Enjoyed MBSJ2024 alot!

Post a non-religious photo you think of as holy.

I will be attending MBSJ2024 (11/26-) and will be staying in Japan for almost a month after the meeting. Hoping to get to know new friends in the field, and also to see my former colleagues. Cannot wait to enjoy sushi🍣 and onsen ♨️! (Been wanting to go back in winter for years)