Syed Zawar Shah
@zawarshah.bsky.social
π€ 193
π₯ 572
π 1
Ph.D. in Vannini lab @HumanTechnopole
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9 months ago
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Syed Zawar Shah
Joachim Frank
9 months ago
You want to build an apparatus for time-resolved cryo-EM? Easy:
bio-protocol.org/en/bpdetail?...
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https://bio-protocol.org/en/bpdetail?id=5193&type=0
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Cees Dekker
9 months ago
New discovery from our
#CDlab
reported in Cell
@cp-cell.bsky.social
today: SMC motor proteins have a left-right βgearboxβ and can switch direction in DNA loop extrusion!
www.sciencedirect.com/science/arti...
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9 months ago
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Alessandro Vannini
9 months ago
Excited to share the (hard) work of
@zawarshah.bsky.social
in its final form:
www.nature.com/articles/s41...
A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work
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Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters - Nature Communications
The snRNA Activating Protein Complex (SNAPc) mediates snRNA transcription by RNA Pol II and III. Here, the authors have used cryo-EM to resolve the structure of the SNAPc-bound RNA Pol III pre-initiat...
https://www.nature.com/articles/s41467-024-55553-8?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20250103&utm_content=10.1038/s41467-024-55553-8
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samlacey.bsky.social
11 months ago
Our review of Intraflagellar transport is out now! We cover lots of the recent advances in our understanding of IFT, and where we think there are still some gaps.
www.nature.com/articles/s41...
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The intraflagellar transport cycle - Nature Reviews Molecular Cell Biology
Intraflagellar transport (IFT) ensures delivery of selected proteins into cilia. The IFT protein complexes IFT-A and IFT-B polymerize at the base of the cilium to form an anterograde train that facili...
https://www.nature.com/articles/s41580-024-00797-x
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