Valerio Sorichetti
@vsorichetti.bsky.social
π€ 262
π₯ 398
π 79
Senior bioinformatician / computational scientist in the Gerlich Lab at IMBA (Vienna Biocenter).
I'm happy to share that I have started a new position in the Gerlich Lab (
@gerlichlab.bsky.social
) at IMBA (
@imbavienna.bsky.social
) as Senior Bioinformatician. Looking forward to contributing to the great science developed in the group! ππ§¬
13 days ago
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Valerio Sorichetti
Gerlich Lab
14 days ago
New preprint out!𧬠How do cells keep replicated sister chromatids linked for DNA repair while folding 3D loops for gene expression? Extrusion folds DNA but separates sisters, while cohesion connects them, risking mutual interference. How do they coexist?π§΅π π
doi.org/10.64898/2026.05.02.722390
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https://doi.org/10.64898/2026.05.02.722390
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Amazing colloquium talk by Christa Schleper from
@univie.ac.at
@archaea-vienna.bsky.social
on how archaea use protrusion to crawl on surfaces!
#archaea
#loki
@istaresearch.bsky.social
5 months ago
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Valerio Sorichetti
Archaea Biology Vienna
6 months ago
Asgard on the move ! Watch our videos!
Biorxiv.org/content/10.1101/2025.11.30.690169v1
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Dynamic protrusions mediate unique crawling motility in Asgard Archaea (Promethearchaeota)
Crawling motility is a hallmark of eukaryotic cells and requires a dynamic actin cytoskeleton, regulated adhesion, and spatially organized signalling pathways1β3. Asgard archaea (phylum Promethearchae...
https://Biorxiv.org/content/10.1101/2025.11.30.690169v1
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Something I was recently discussing with some colleagues: is the work of computational scientists closer to the one of experimentalists or to the one of theorists working on analytical models?
7 months ago
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I tried it -- very impressive! A caveat, however -- it might make you feel as if your published papers aren't as good as you thought π
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7 months ago
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Our paper on chromosome segregation in the archaeon Sulfolobus Acidocaldarius has been published in PNAS! This has been a great collaboration with
@joeparham19.bsky.social
and the rest of
@buzzbaum.bsky.social
's team. Stay tuned for more to come!π
@istaresearch.bsky.social
doi.org/10.1073/pnas...
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Temporal and spatial coordination of DNA segregation and cell division in an archaeon | PNAS
Cells must coordinate DNA segregation with cytokinesis to ensure that each daughter cell inherits a complete genome. Here, we explore how DNA segre...
https://doi.org/10.1073/pnas.2513939122
7 months ago
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Grateful for this opportunity of taking part in the 9th International Soft Matter Conference in beautiful Crete and presenting my research! It's been a great week of science, stimulating discussions and great food in a beautiful scenery πποΈ
8 months ago
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It has been a great workshop! Thanks to
@romanstano.bsky.social
, Peter, Emanuela and Christos for giving me the opportunity to present my work :)
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8 months ago
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Valerio Sorichetti
David BrΓΌckner
9 months ago
Super excited that our group will be supported by an ERC Starting Grant! In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions. We'll have PhD and Postdoc positions available, please get in touch if interested!
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Our paper on the nonequilibrium mechanics and remodelling of collagen-IV networks is finally out on
@prxlife.bsky.social
! It has been a long and exciting scientific journey, led by
@billiemeadowcroft.bsky.social
!
@ivnpla.bsky.social
@yanlanmao.bsky.social
journals.aps.org/prxlife/abst...
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Nonequilibrium Remodeling of Collagen IV Networks in Silico
Active bond remodeling enables collagen IV networks to have a range of responses to strain while maintaining their mechanical integrity.
https://journals.aps.org/prxlife/abstract/10.1103/gdd5-rnh7
9 months ago
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Sally Rooney books are kinda neat until you read a couple and realize that all the plots and characters are exactly the same...
9 months ago
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Sass de Putia, Dolomites!
9 months ago
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The Dolomites really are a special place. Very lucky to have had so many days of great weather! β°οΈπ₯Ύ
9 months ago
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A stambecco (ibex) with her baby π
9 months ago
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Valerio Sorichetti
Institute of Molecular Biotechnology
9 months ago
Scientific curiosity at IMBA inspired this year's art series, created from research images. Today's kaleidoscope is based on an artistic rendering of the spiral staircase model of the mitotic chromosome, produced by the Goloborodko lab using new tools for analyzing 3D chromosome structure.
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And it's finally published on
@prxlife.bsky.social
! Thanks to Paul Robin (Hannezo lab) ,
@ivnpla.bsky.social
(Ε aric lab),
@aharmendariz.bsky.social
(Cuylen lab). It's been a very stimulating and highly satisfying journey! π§¬
journals.aps.org/prxlife/abst...
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9 months ago
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Sass dla Crusc in the Dolomites π
9 months ago
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So satisfying when the last round of proofs for your paper comes back the day before you leave for vacation! π
10 months ago
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Is it just me or Google search results got significantly worse recently?
10 months ago
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Valerio Sorichetti
Anton Goloborodko
10 months ago
We found a new asymmetry in the large-scale chromosome structure: sister chromatids are systematically shifted by hundreds of kb in the 5β²β3β² direction of their inherited strands! The work was led by Flavia Corsi, in close collaboration with the Daniel Gerlich lab.
www.biorxiv.org/content/10.1...
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Wow!! This is super cool!
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11 months ago
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Valerio Sorichetti
Randall Munroe
11 months ago
Good Science
xkcd.com/3101/
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First time it happens to me: the book I'm reading (Thinking, Fast and Slow by Daniel Kahneman) is missing 49 pages π
12 months ago
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With the explosion in popularity of Gen AI tools, I wonder if we will go back to having more oral exams in schools and universities. Which in Italy we already do, because we haven't really updated our teaching methods in like 50 years... π
12 months ago
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@buzzbaum.bsky.social
@joeparham19.bsky.social
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12 months ago
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How do archaea partition their genome just at the right time before cell division? Check out this new
#preprint
if you want to know! A great collaboration with Joe and the
@buzzbaum.bsky.social
lab! π¦ π§¬
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12 months ago
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The workshop on polymers and biomolecular condensates in MeiΓen was great! I've learnt a lot and met some great people, and got to visit the beautiful MeiΓen and Dresden! Thanks to the organizers
@albertilab-tud.bsky.social
, Arash and Jens!
12 months ago
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MeiΓen at night! π€©
12 months ago
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Very engaging talk by Daniel Bonn on rheology and phase separation of active (and in some cases drunk) worms! πͺ±πͺ±πͺ±
about 1 year ago
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Happy Star Wars day!
about 1 year ago
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Valerio Sorichetti
Tom Gauld
about 1 year ago
A recent
@newscientist.com
cartoon
#fungi
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I love papers like this πΉ Discovering complexity in mundane things!
www.science.org/doi/10.1126/...
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Geometrically frustrated rose petals
Growth and form are deeply interconnected, in a manner often mediated by mechanical instabilities arising from geometric incompatibilities. Although Gauss incompatibility has long been recognized as t...
https://www.science.org/doi/10.1126/science.adt0672
about 1 year ago
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Valerio Sorichetti
Itai Yanai
about 1 year ago
π₯New Night Science paper!! Discovery happens when your initial plans fall apart but it requires you to have a particular mindset: it's not extraverted, orderly, neurotic or agreeable that's the most important β discovery requires an OPENNESS to new ideas and unexpected insights.
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Valerio Sorichetti
Mark Hamill
about 1 year ago
I remember it being unpleasant & a lot less fudge-y.
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Super cool experiments by Alfredo and the team!! The laser ablation one in particular is very clever. Definitely check this out if you're interested in the cytoskeleton or active matter in general π
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about 1 year ago
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Made Mapo Tofu (vegetarian version, with shiittake mushrooms instead of meat) for the first time yesterday. Pretty happy with the results! π
over 1 year ago
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Typical researcher
over 1 year ago
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Valerio Sorichetti
Morgan Tingley
over 1 year ago
The insanity of being a fire ecologist in the epicenter of a major fire event, bags packed and ready to evacuate, watching active fire from my window, while taking media requests and explaining to the public, for the 100,000th time how climate change is largely responsible for this
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This show was incredible
over 1 year ago
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Cacio e Pepe is a notoriously difficult pasta recipe. Luckily, we can find the perfect recipe using science! ππ§βπ¬ Most importantly, be sure to avoid the "mozzarella phase"! Great article by
@vicioms.bsky.social
and colleagues π
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over 1 year ago
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The New Year's Eve fireworks in Naples ππ
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over 1 year ago
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Valerio Sorichetti
Oded Rechavi
over 1 year ago
When you get an email from a post doc CCing the big shot boss
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View of Naples from Castel Sant'Elmo π°
over 1 year ago
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Valerio Sorichetti
Alfredo Sciortino
over 1 year ago
It's the time of the year when I make a Christmas themed experiment to celebrate another year gone by: this year, a micropatterned branched actin network with myosin, aka a Christmarp(2/3) tree, doing weird stuff. Happy holidays Bluesky! π₯³π₯³π₯³
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Valerio Sorichetti
bioRxiv Biophysics
over 1 year ago
The mitotic chromosome periphery: a fluid coat that mediates chromosome mechanics
https://www.biorxiv.org/content/10.1101/2024.12.21.628209v1
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Valerio Sorichetti
Alex Klotz
over 1 year ago
Davide isn't here yet so here's a nice review he just wrote on kinetoplast biophysics
academic.oup.com/nar/advance-...
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Kinetoplast DNA: a polymer physicistβs topological Olympic dream
Abstract. All life forms are miraculous, but someΒ are more inexplicable than others. Trypanosomes are by far one of the most puzzling organisms on Earth: t
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae1206/7925237
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Loop extruders induce twist on DNA strands! Very cool!
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over 1 year ago
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Valerio Sorichetti
Stephane Vassilopoulos
over 1 year ago
Clathrin-coated pits working overtime in your heart this weekendπ¬
#ClathrinLife
#WeekendScience
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reposted by
Valerio Sorichetti
Christoph Dellago
over 1 year ago
YES!!βοΈ
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