Anna Dart
@annaedart.bsky.social
π€ 1533
π₯ 551
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Chief Editor of Nature Reviews Cancer Views are my own
Check out our latest Focus issue highlighting why the mechanisms of ageing, which contribute to cancer development, progression & treatment are so important in our rapidly ageing global population π
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12 days ago
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Anna Dart
Nature Reviews Cancer
3 months ago
#Comment
π¨ Asghar&Chung highlight cancer applications of digital twins, integrating molecular data & drug responses to inform personalized treatment & accelerate drug development through clinical trial simulation. πβ¬οΈ
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Application of digital twins for personalized oncology - Nature Reviews Cancer
Digital twins are virtual representations that evolve over time with new data inputs. In this Comment, Asghar and Chung describe cancer applications of digital twins that include the integration of molecular information and individual drug responses of patients, and explain how they can inform individualized treatment, accelerate drug development through clinical trial simulation and enable the exploration of multiscale relationships in the entire human body to drive new therapeutic discoveries.
https://bit.ly/3GeKsH2?utm_source=dlvr.it&utm_medium=bluesky
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Anna Dart
Nature Reviews Cancer
3 months ago
#Review
π¨ Henry & DeGregori @jdegregori.bsky.socialβ¬ discuss models and methods used to study the connection between ageing and cancer, advocating advocating for the wider adoption of age-appropriate models of cancer to improve clinical translation πβ¬οΈ
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Modelling the ageing dependence of cancer evolutionary trajectories - Nature Reviews Cancer
In this Review, Henry and DeGregori discuss the contributions of the various models and methods used to study the connection between ageing and cancer, highlighting the strengths and limitations of those models and technologies, as well as advocating for the wider adoption of age-appropriate models of cancer to improve our clinical translation of approaches to prevent and treat human cancers.
https://bit.ly/3GswOA7?utm_source=dlvr.it&utm_medium=bluesky
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Anna Dart
Nature Reviews Cancer
3 months ago
#Perspective π¨ Lazure and Gomes argue that metabolic changes that occur as a result of #ageing may shape tumour initiation and progression and the development of metastatic disease. β¬οΈ π
https://bit.ly/3IkNY...
#Perspective
#ageing
moffittnews.bsky.socialβ¬
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Cancer progression through the lens of age-induced metabolic reprogramming - Nature Reviews Cancer
In this Perspective, Lazure and Gomes argue that metabolic changes that occur as a result of ageing may shape tumour initiation and progression and the development of metastatic disease.
https://bit.ly/3IkNY31?utm_source=dlvr.it&utm_medium=bluesky
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Anna Dart
Nature Reviews Cancer
2 months ago
NEW content online!
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Metabolic adaptations of brain metastasis
Nature Reviews Cancer, Published online: 24 July 2025; doi:10.1038/s41568-025-00848-1In this Review, Parida and Malladi summarize the metabolic adaptations of tumour cells upon dissemination to the brain, outline the metabolic crosstalk between cancer and brain-resident cells and discuss potential strategies to target these adaptations to improve outcomes for patients with brain metastasis.
https://www.nature.com/articles/s41568-025-00848-1?utm_source=dlvr.it&utm_medium=bluesky
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Anna Dart
Nature Reviews Cancer
3 months ago
Perspective π¨ Orsolya Vincze @OVincze, Thomas Pradeu &Co discuss how cancer research can be advanced using comparative oncology and call for the increased use of non-conventional model organisms to advance cancer prevention and treatment. π β¬οΈ
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Advancing cancer research via comparative oncology - Nature Reviews Cancer
Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular and cellular mechanisms underlying the remarkable cancer resistance of some taxa. Therefore, this Perspective by Vincze et al. calls for the increased use of non-conventional model organisms in cancer research to advance cancer prevention and treatment strategies.
https://bit.ly/4noWcqO?utm_source=dlvr.it&utm_medium=bluesky
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Anna Dart
Nature Reviews Cancer
3 months ago
Our July issue is LIVE! ππ₯΅ποΈ It features articles on: - Targeted protein degradation for cancer therapy - Advances in therapeutic cancer vaccines - The TGFΞ² paradox in HPV-driven cancer - The paths to metastasis Happy reading! π π
https://www.nature.c...
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Anna Dart
Nature Reviews Cancer
4 months ago
Our June issue is now LIVE!π It features articles on: - Challenges of SCLC heterogeneity & phenotypic plasticity - The fibroinflammatory response in
#cancer
- Moonlighting functions of glucose metabolic enzymes & metabolites in cancer - PIPKs in cancer ππ
www.nature.com/nrc/volumes/...
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Anna Dart
Rita Strack
5 months ago
I don't think I posted about this yet. COME WORK WITH US AT NATURE METHODS! This is a rare opportunity, and we can't wait for our new colleague. Feel free to contact me with questions.
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I'll be there, so make sure you sign up for what promises to be a fantastic meeting!
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5 months ago
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What an honour to be part of this meeting! Fantastic scientists and clinicians in a fantastic setting, brainstorming how to advance this field and find life-saving cures for patients with glioblastoma.
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6 months ago
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And the moment you have all been waiting for...our top downloaded article of 2024! π Well worth a read!
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8 months ago
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And just off the top spot....π
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8 months ago
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And number 3....π
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8 months ago
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In at number 4....
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8 months ago
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And the countdown begins again this week with number 5...π
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8 months ago
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Anna Dart
Nature Reviews Cancer
8 months ago
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Dendritic cell maturation in cancer
Nature Reviews Cancer, Published online: 07 February 2025; doi:10.1038/s41568-024-00787-3Dendritic cells (DCs) shape the adaptive immune response to peripheral tissue antigens and, as such, are crucial for mounting an effective antitumour immune responseβ¦
https://www.nature.com/articles/s41568-024-00787-3?utm_source=dlvr.it&utm_medium=bluesky
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And in at number 6 π Top 5 coming next week! π Exciting!
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8 months ago
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And at number 7....π
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8 months ago
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In at number 8...π
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8 months ago
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And in at number 9....π
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And in at number 10 is....π
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Well worth a read! Hanahan et al. argue that many normal cell types are hard-wired with latent functions that can be triggered to prevent inappropriate immune attack. An intrinsic capability that is co-opted by tumours π
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8 months ago
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Anna Dart
Nature
9 months ago
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X
https://go.nature.com/42tH8Ai
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Blueskyβs science takeover: 70% of Nature poll respondents use platform
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.
https://go.nature.com/42tH8Ai
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Eric Topol
9 months ago
Welcome immigrants from X interested in science to the friendlier skies of
@bsky.app
, as documented by a new
@nature.com
survey (but you already knew that π) "Bluesky is much better for science. There is much less toxicity, misinformation, and distractions."
www.nature.com/articles/d41...
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Katrina Ray
9 months ago
Welcoming the newest members of the
#NatureReviews
family
@natrevbiodiv.bsky.social
&
@natrevcleantech.bsky.social
on their launch week! You can follow them and more Reviews journals (and a few Editors) in this starter pack π§ͺ
go.bsky.app/KcxvQLp
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Anna Dart
Gabrielle Brewer
9 months ago
I just registered for the upcoming
@keystonesymposia.bsky.social
tumor metabolism meeting in Vancouver! Anyone else attending?! We can chat about publishing &
@natrevcancer.bsky.social
!! π€πβ¨
#KSTumorMetab25
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Open our January issue just out as an early Xmas present π
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10 months ago
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Anna Dart
Andreas Wernitznig
11 months ago
As a frequent user of
depmap.org
, I am impressed about the outstanding achievements summarized in this Nature Reviews cancer article:
doi.org/10.1038/s415...
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The present and future of the Cancer Dependency Map - Nature Reviews Cancer
The Cancer Dependency Map (DepMap) is a data repository and research platform that can be utilized to systematically identify cancer vulnerabilities. Here Arafeh, Shibue et al. outline the current lim...
https://doi.org/10.1038/s41568-024-00763-x
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Anna Dart
Nature Reviews Cancer
10 months ago
Hello
#cancersky
! It's official, we're here! Follow us for all things
#cancerresearch
and
#oncology
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Anna Dart
Nature Portfolio
10 months ago
One of the biggest questions we get is when will our journals be here. We thank you for your patience. You can now follow our journals with this starter pack!
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All systems go! Come follow
@natrevcancer.bsky.social
& the other
#NatureReviews
titles π
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#REVIEW
π¨ Kratz highlights the genetics of cancer in children, examining cancer predisposition syndromes + genes, embryonic mosaicisms & polygenic risk scores, focusing on their role in cancer prediction, prevention, surveillance & therapy. Read it π
bit.ly/3ZHhZAA
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Re-envisioning genetic predisposition to childhood and adolescent cancers - Nature Reviews Cancer
Genetic predisposition is the major known cause of cancer in children and adolescents. In this Review, Kratz highlights the genetic architecture of cancer in children and adolescents, examining cancer...
https://bit.ly/3ZHhZAA
10 months ago
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Includes articles from our journal
@natrevcancer.bsky.social
π Well worth a browse!
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10 months ago
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Gabrielle Brewer
10 months ago
#natureconference
π¨ I'm co-organizing a conference on Gene & Cell Therapies with Joao Monteiro
#NatureMedicine
, Pep PΓ mies
#NatureBiomedicalEngineering
&
@francesari.bsky.social
#Nature
. Come join us in Wenzhou in April! πmore details:
conferences.nature.com/event/GeneCe...
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HOME - Gene & Cell Therapies: the path to clinic
https://conferences.nature.com/event/GeneCellTherapies/summary
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#NatureReviewsCancer
December issue is LIVE! π¨πβοΈ It features Reviews on: - Cancer induced pre-conditioning of distant organs, - Strategies to investigate the biology of early cancer, - Precursor multiple myeloma - & a
#Roadmap
on mRNA splicing in the clinic
bit.ly/4i3cnaG
10 months ago
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Anna Dart
Barbara Marte
10 months ago
a great opportunity to join the Nature team: we're looking for a neuroscience editor, ideally with a strong record in systems neuro:
springernature.wd3.myworkdayjobs.com/SpringerNatu...
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Associate or Senior Editor, Nature
Job Title: Associate or Senior Editor, Nature Locations: New York or Berlin (Hybrid working model) Application Deadline: December 15th, 2024 About Springer Nature Group Springer Nature opens the doors...
https://springernature.wd3.myworkdayjobs.com/SpringerNatureCareers/job/New-York/Associate-or-Senior-Editor--Nature_JR101464
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If you want to follow me and many of the other fantastic editors working across the Nature Portfolio, check out the starter park below π«΅π
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10 months ago
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Gabrielle Brewer
11 months ago
More
#NatureReviewsCancer
updates π¨ We recently launched a collection on the
#microbiome
in cancer. While its role is still debated, the collection presents a selection of articles from
#SpringerNature
journals to highlight our current understandings.π§«π¦ ππ
bit.ly/48u8WFH
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The microbiome in cancer
The gut microbiome plays a crucial role in cancer development and progression, by influencing the host immune system and metabolism.
https://www.nature.com/collections/gahafacddj
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