New online! Cardiotoxicity of T cell immunotherapies #CardioSky

Thanks for the shoutout, @domucla.bsky.social!

Clonal hematopoiesis of indeterminate potential (CHIP) is common in older individuals, but its connection with aortic valve stenosis was unclear. Wesley T. Abplanalp & team now show CHIP activates procalcific pathways in macrophages and promotes AVS: www.jci.org/articles/vie...

We did a deep dive into aortic stenosis genetics, and took first steps to understand the genetics behind normal human variation in flow across the aortic valve.

The federal government’s demand of $1 billion from @UCLA would devastate the nation’s best public university, cut off life-saving care, halt tech and economic growth and reduce educational access. Stand with UC to protect our vital mission: www.universityofcalifornia.edu/get-involved...

BREAKING: The Trump administration is seeking $1 billion+ from the University of California to restore UCLA's frozen federal funding. The payout would far exceed any made by universities so far. UC has not agreed to it, sources say. www.latimes.com/california/s...

Trump freezes $200 million in UCLA science and medical research funding, citing antisemitism www.latimes.com/california/s... @latimes.com

In this month’s issue of #JACCBTS, Jønck, et al. explore the effects of cytokine inhibitors on cardiovascular adaptability in rheumatoid arthritis (RA). Read below to see what they found! 🧵 1/9 @jaccjournals.bsky.social

I said my main goal of this trip was to meet with Kilmar. Tonight I had that chance. I have called his wife, Jennifer, to pass along his message of love. I look forward to providing a full update upon my return.

The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma Excited to have contributed to this work. #AHA25 www.thelancet.com/commissions/... @thelancet.bsky.social

In these uncertain times, celebrating novel science is one way to stay grounded and hopeful. In this month’s issue of #JACCBTS, Song, et al. investigate mitochondrial function in aortic valve calcification. Join me to see what they found! 🧵 1/10 @jaccjournals.bsky.social

Mike spotted this before the rest of us. 🫡 Publications from 2025 are shared more on Bluesky than on X/Twitter.

I have confirmation from several sources now that all T32s, many F30s and F31s, and most or all Center awards (P30, P50) have been terminated at Columbia. This is quite damaging to research and to individuals. This is pure terrorism and cannot be legal. But litigation will take time...

List includes Harvard University, George Washington University, Johns Hopkins University, New York University, Northwestern University, the University of California, Los Angeles; the University of California, Berkeley, the University of Minnesota, and the University of Southern California.

NIH budget: $ 48b Musk wealth: $351b Both are mostly funded by your tax dollars But only one might save your life . . . . Sources: www.nih.gov/about-nih/wh... Search results: elon musk net worth g.co/kgs/6c8YEuB @standupforscience.bsky.social

During Rare Disease Week, patients and advocates were in D.C. for an event with the NIH, FDA, and HHS to highlight work being done on treatments and cures. It was abruptly canceled. Why? The administration fired the people organizing this important event and advancing this work.

Duke is one of the largest biomedical research enterprises in the country. A cut of this magnitude (15%cap on F&As) would result in thousands of lost jobs at Duke & potentially tens of thousands across NC. Sources: medschool.duke.edu/about-us/fac... & www.unitedformedicalresearch.org/nih-pdf/?sta...

Strong & timely presidential advisory from @ahascience.bsky.social 👏🏼 www.ahajournals.org/doi/10.1161/...

Welcome immigrants from X interested in science to the friendlier skies of @bsky.app, as documented by a new @nature.com survey (but you already knew that 😉) "Bluesky is much better for science. There is much less toxicity, misinformation, and distractions." www.nature.com/articles/d41...

In this month’s issue of #JACCBTS, Brambilla, et al. explore the role of platelet function in long COVID. Read below ⬇️ to see what they found! 🧵 1/n @jeffhsumd.bsky.social @jaccjournals.bsky.social @vascularimmuno.bsky.social @jeanwassenaar.bsky.social