Time to stop dicking around and approve it now.

"Reannotation is not the most glamorous part of genomics. It does not generate splashy press releases and doesn’t feed the obsession with CNS papers. But infrastructure matters. And so does interpretation consistency."

Will Stancil co-authored this paper showing that "artist housing" can be mostly be seen as expensively subsidized affordable housing earmarked to white people. Pretty good research!

The City of Boston has chosen to address our historic housing shortage by...further limiting how many homes can be built in Boston. What are we even doing here?

INTO MY VEINS Now do this fo rall permitting

Have you seen how cheap Spanish metros are to build? Well actually, I have and I will tell you all about it! I had the chance to visit the extension of line 11 in Madrid, where I learned a lot about their construction methods, peculiarities and processes. Let me take you along! A thread 🧵 (1/11)

Josh Barro: "John Fetterman and Graham Platner both flailed into adulthood, living off their affluent parents while not amounting to much. Why have leftists decided this is a good resume for the U.S. Senate?" open.substack.com/pub/joshbarr...

Ken Paxton just gave an Epstein-style deal to a pedophile. Paxton released Adam Hoffman — an admitted child rapist — back on our streets after Paxton’s rich lawyer friend got involved. The Epstein Class has no place in Texas. Ken Paxton has no place in the US Senate.

It is simply dishonest for anyone in Boston to claim that "macroeconomic conditions" are solely to blame for our construction slowdown. NYC has the same high interest rates, land & labor costs as Boston. The difference is policy reforms under city's power to accelerate housing production citywide.

We could do this in Boston...it would just take leadership that is committed to ending our housing crisis.

Yes. Since having kids, I’ve become even more fervent in my views on street safety, sidewalks, etc. On the flip side, I’ve become far less patient with urban disorder. You feel vulnerable when you’re with young kids. I don’t want to be near people shouting, using drugs in public, etc.

@mayorwu.boston.gov is this what you were hoping for when you removed all the delineators on every dedicated bike lane in Boston? That drivers would start taking them full speed? WHY ARE YOU RISKING OUR LIVES @streets.boston.gov @wutrain.bsky.social??? @universalhub.com @mass.streetsblog.org

Why doesn't LA have a policy research and advocacy think tank dedicated to making the city better? Like SPUR, Sightline Inst., MPC, RPA, etc. LA has so much untapped potential - there should be an org working on furthering ideas to support its growth.

Our simulations show that the act isn’t needed for minority representation in the South, if partisan gerrymandering were checked. www.nytimes.com/2026/05/17/u...

Boston bikers and safe street advocates please join the Ride of Silence the morning of Wednesday May 20. We will ride from Melnea Cass to City Hall for a silent vigil for the 38 peds and bikers killed since Wu took office #VisionZeroBoston Register here: secure.everyaction.com/FXXCaFeCQUGS...

Always fun to read an article about how people respond to incentives and how leaders are shocked by this. Cambridge cut its penalty for not moving during street cleaning and, shocking, more people parked on the street during street cleaning www.bostonglobe.com/2026/04/30/m...

This take by @mjtoma.bsky.social misses a few things. 1. The biggest US crop, corn, is almost all hybrid, so you can't save seeds 3. Farmers can do math and choose patented seeds because yields are better 2. Non-patented seeds are available in every crop I know of newrepublic.com/article/2098...

Love this whole process of rediscovering why insurance law is so strict about policy holders have an insurable interest in the risk being underwritten

Never forget they harassed and tried to get rid of the grad student who dared to question their ridiculous claims.

What’s better than a tax on “luxury” second homes? A tax on expensive land, not dependent on who owns it.

[LA Metro fare inspections per month] 2015: >600k 2017: >300k 2019: <50k Now: <10k Aaaaanyway, where did all the crime and disorder on LA Metro come from?

Connecticut: no, you can’t build solar farms or clean energy infrastructure. No, you can’t build battery storage. No, you can’t build homes. No, you can’t sell your farm even if it’s no longer viable. No, your kids can’t attend our schools. www.ctinsider.com/politics/art...

Delivery drivers are unloading in the Washington St bike lane 😬. People who bike in Boston deserve better. This kind of malpractice is not an inconvenience, it's endangerment @mayorwu.boston.gov @streets.boston.gov @mohammedmissouri.bsky.social @lizbreadon.bsky.social @edflynnforboston.bsky.social

The anti yimby left and even some of the neutral on housing left deeply oppose integration, often in the name of opposing gentrification. It's astounding to see land use policies sold as equity that only prolong the deepest segregation in otherwise prosperous cities.

This is correct. I think the underlying issue this piece kinda of elides tho is that a bunch of Americans online are convinced that they are communists, when they are actually just libertarians who use leftist rhetoric to rationalize their libertarianism.

Wu to transit: Drop Dead Columbus ave in this area is massively wide and has ~no abutters. If you can't put bus lanes here, you can't do anything.

New paper showing that much of the apparent success of protein language models in predicting mutational effects is a mirage: These models mostly memorize sites. 1/ www.biorxiv.org/content/10.6...

Matt Mahan's platform is OK but the problem is I don't trust him personally on this stuff. San Jose has been out-built by San Diego and Sacramento, and even places like Santa Rosa, Santa Barbara, and Santa Cruz. Why doesn't his housing platform translate to results for San Jose?

You tend to only see these mansion combinations in neighborhoods zoned/landmarked low-density. They thrive with R6 zoning and landmark districts – West Village, UES/UWS side streets, Boerum Hill. Not the UES/UWS avenues, Midtown, or DTBK. You can defeat mansionization through high-density zoning.

Remarkable how hard it is for Harvard to fire a notorious pervert who was always obviously funded by Epstein only.

Boston has for years enabled NIMBY nonprofits to block housing construction nearby, even as they point to no real harms and have a history of refusing to buy the land in question www.bostonglobe.com/2026/02/25/b... Now they're bankrupting nuns. This should be unacceptable in polite society

Oregon's state senate just voted to ban unfunded inclusionary zoning, recognizing that it makes housing *less* affordable, not more affordable.

These people are shortsighted, and wrong, and their ability to express these policy ideas is premised on the ability to displace the costs of their lifestyle preferences onto the public and (poorer) urban dwellers in particular. But there are a lot of them!

V. perceptive line in this: "Many prefer the smaller, less crowded, slower-paced Providence of today, where you can find a parking space downtown on a weekday in front of one of the old 20th-century office buildings." A fact of US life that there is a very large pro-urban decline constituency.

The MA housing crisis is a moral issue, but there is an underlying political crisis as well. People move to cheaper places if they can’t afford sky-high housing costs. “Blue” states are throwing away electoral power to “Red” states in congressional apportionment and the EC because of NIMBYism.

You can get money for the MBTA or you can pay Cambridge a 25% tax on new home construction but you can’t do both

Wow – real asking rents in Jersey City are completely flat since 2017 www.nytimes.com/2026/01/08/n... (🎁🔗)

In the topsy-turvy world of California housing policy, building six townhouses instead of a single McMansion will result in hundreds of thousands of "impact" fees that have nothing to do with impacts and "affordability" mandates that guarantee housing unaffordability.

Between this and the recent dealer stabbing, it's clear that the horrendous management that led to BMC turning its front lawn into a drug market in spring of '25 was not an isolated incident. We deserve better.

Public engagement the way most places do it is a kind of performative dance. Everyone plays their socially designated roles and there's very little content to it, because all the planners are allowed to say is "thank you for your comment, we'll take it into consideration."

People stay stuff because it's socially approved, and then they start to believe it, and elected officials probably don't know better than to accept it, and civil servants generally don't have political cover to push back, so stuff that "everybody knows" becomes conventional wisdom.

A *huge* part of discourse is that there are certain objections to change that are coded as socially acceptable, even when they're the opposite of reality and standing in for the true agenda (plain old NIMBYism). School stuff is one of those items (others include affordability and trees).

A major theme of conversations at NeurIPS this year: Protein binder design is powerful, but ~no one believes the strongest claims about its efficacy. Innovators + academics want to support one another, but whom does it benefit when we claim clearly overfit zero shot results? 1/

This is what happens when you let NIMBYs block cleaner, cheaper, and much less polluting natural gas. We're not getting enough nuclear or offshore wind immediately; the failure to build gas infra is impoverishing, sickening, and damaging us all in New England.

Incredible we built a society where tens of thousands of people are forced to live in this misery just because the wealthiest people in America want more parking and because left-NIMBY cranks still won't let go of their housing Lysenkoism which insists that new housing causes gentrification.

“Pioneer New England Legal Foundation filed a lawsuit in state Land Court against the City of Cambridge on behalf of developer Columbia St, LLC, challenging the City’s inclusionary zoning ordinance.” pioneerlegal.org/pioneer-new-...

Still thinking about this article. It’s always been a sore spot in YIMBY circles that so many progressive foundations pour money into NIMBYism, and I’m glad it’s finally being aired in public. Keep talking about it. www.insidephilanthropy.com/home/philant...

Straight from the horse's mouth: “These models somehow just generalize dramatically worse than people. It's a very fundamental thing.”

"per square foot, affordable housing cost more 1.5 times as much to build in California as market-rate housing" www.nytimes.com/2025/11/23/o...

The problem isn't his ties to Jeffrey Epstein. It's that he plotted to abuse his position as the mentor of a grad student by conditioning his support for her work on "romance/sex." Every report that fails to mention the true offense is failing (again) the student who endured this.