Very happy for this to finally be published! We developed new machine learning methods for scalable mapping of synaptic connectivity using holographic optogenetics and compressed sensing. www.nature.com/articles/s41...

We present our preprint on ViV1T, a transformer for dynamic mouse V1 response prediction. We reveal novel response properties and confirm them in vivo. With @wulfdewolf.bsky.social, Danai Katsanevaki, @arnoonken.bsky.social, @rochefortlab.bsky.social. Paper and code at the end of the thread! 🧵1/7

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

Excited to co-organize our NeurIPS 2025 workshop on Foundation Models for the Brain and Body! We welcome work across ML, neuroscience, and biosignals — from new approaches to large-scale models. Submit your paper or demo! 🧠 🧪 🦾

Excited to announce the Foundation Models for the Brain and Body workshop at #NeurIPS2025! 🧠📈 🧪 We invite short papers or interactive demos on AI for neural, physiological or behavioral data. Submit by Aug 22 👉 brainbodyfm-workshop.github.io

Neural Encoding and Decoding at Scale (NEDS) is now accepted to @icmlconf.bsky.social as a spotlight (top 2.6%)! 🧠 🧪

Super cool. 😀 Exciting to see the practical use cases of electrical stimulation for treating neurological disorders

We’re hiring postdocs to join my lab at UNC. If you’re interested in adolescence, brain, and social development, DM me. Our work incorporates fMRI, social media, and longitudinal methods. We study risks and opportunities in adolescence. If you’re at #SRCD2025 and want to meet, please reach out!

I asked "on the other platform" what were the most important improvements to the original 2017 transformer. That was quite popular and here is a synthesis of the responses:

Whoever is at the @iclr-conf.bsky.social workshops, feel free to reach out to meet! Looking for fun neuro conversations since there aren’t any neuro workshops 😢

Scaling models across multiple animals was a major step toward building neuro-foundation models; the next frontier is enabling multi-task decoding to expand the scope of training data we can leverage. Excited to share our #ICLR2025 Spotlight paper introducing POYO+ 🧠 poyo-plus.github.io 🧵

Thrilled to share our state-of-the-art method for in vivo cell-type classification and brain region localization, NEMO, which is now now a spotlight at @iclr-conf.bsky.social ! We use NEMO to characterize the electrophysiological diversity of cell-types across the entire mouse brain. 🐭 🧪 🧠

Agreed! But here's a note of caution: in the brain, different behavioral contexts can engage completely different neurons! Julie Lee in our lab published this in 2022 (and I'm still digesting the implications). "Task specificity in mouse parietal cortex" www.cell.com/neuron/fullt...

Thanks so much for the shout-out, and congrats on your exciting work!! 🎉 🙂 Also, a good reminder to share that our work is now out in Cell Reports 🙏🎊 ⬇️ www.cell.com/cell-reports...

Very cool work here from @colehurwitz.bsky.social and others, and an important step towards a proper foundation model for neuroscience. Wonderful to see the scaling effects of moving from single session to multisession! (Also, a great use of the IBL data, IMO). #NeuroAI 🧠📈 🧪

Another step toward a foundation model of the mouse brain: "Neural Encoding and Decoding at Scale (NEDS)" Trained on neural and behavioral data from 70+ mice, NEDS achieves state-of-the-art prediction of behavior (decoding) and neural responses (encoding) on held-out animals. 🐀

Interested in foundation models for #neuroscience? Want to contribute to the development of the next-generation of multi-modal models? Come join us at IVADO in Montreal! We're hiring a full-time machine learning specialist for this work. Please share widely! #NeuroAI 🧠📈 🧪

Amazing work led by @ninelk.bsky.social. This work introduces BAND, a new approach for modeling the dynamics underlying neural and behavioral data. Using this approach, @ninelk.bsky.social was able to capture feedback-driven motor corrections which were previously missed!

I'll be giving a talk at the foundation model workshop #Cosyne2025 tomorrow: neurofm-workshop.github.io In response to @thetransmitter.bsky.social article by @tyrellturing.bsky.social & Eva Dyer I'll be talking about: How do "foundation"/AI models help us (experimenters) study the brain?

Eva Dyer and I wrote an opinion piece for @thetransmitter.bsky.social on why neuroscience needs to embrace complexity and accept the "bitter lesson" by using a data-driven regime at scale. With commentary from several wonderful researchers! 🧠📈 #NeuroAI 🧪

Cosyne is this week! Looking forward to catching up with whoever is there. :-) #Cosyne2025 If you are sticking around for workshops, come checkout our 2-day workshop on building foundation models for the brain: neurofm-workshop.github.io 🧠 🧪

The International Brain Laboratory reproducibility platform paper is now published at eLife. An amazing effort by many different labs and individuals to understand and improve the reproducibility of electrophysiological measurements in mice. 🧠

Join us at #COSYNE2025 to explore recent advancements in large-scale training and analysis of brain data! 🧠🟦 We also made a starter pack with (most of) our speakers: go.bsky.app/Ss6RaEF

Super excited to be co-organizing this. 😄 We have an amazing list of speakers and some fun panel discussions planned. Come join us!

"I think there's real risk of a generation or more of data being lost." - Dr. Michael Greicius, neurology professor at Stanford University, on the damage Trump's cuts to NIH research will do to progress on a treatment for Alzheimer's disease, adding as much as 20 years to the timeline.

Petition to Reverse the NIH Indirect Cost Cap. Sign and Circulate. Mobilize. Organize. chng.it/LS57Nk7r6k

The overlapping activity in the animals’ nucleus accumbens may underpin pair bonding, a new preprint suggests. www.thetransmitter.org/social-behav... By @shaena.bsky.social 📹 Courtesy of Paul Muhlrad @wormpicker.bsky.social #neuroskyence

Curious how place cells adapt to uncertainty in reward location? We found that predictable changes boost “reward place cells” & warp hippocampal maps. Check out our new preprint: with Feng Xuan, Jack Mellor, Peter Dayan and Dan Dombeck: www.biorxiv.org/content/10.1...

Amazing. Cognition is about 100,000,000 times slower than our sensory systems 🤯

I promised to write about my thoughts on the status of the field of neuroAI, some of the big challenges we are facing, and the approaches we are taking to address them. This is super selective on the topic of finding a good model but in my view it affects the field as a whole. Here we go. 🧵

Come check out our poster at #NeurIPS2024 (Thursday 11am PST in the East Exhibit Hall A-C). Excited to get feedback on our new direction for neurofoundation models. :-)

Heading to #NeurIPS2024 next week. Looking forward to seeing everyone there!

1/ We just open-sourced two large wrist electromyography (EMG) datasets - one towards typing without a keyboard and the other for predicting hand poses - with baselines. We believe these will help advance research into making high bandwidth non-invasive neuromotor interfaces a reality!

Ported over from X! What will a foundation model for the brain look like? 🧠 We argue that it must be able to solve a diverse set of tasks across multiple brain regions and animals. Check out our NeurIPS paper which introduces a multi-region, multi-animal, multi-task model arxiv.org/abs/2407.14668

BCIs list! Still finding folks on here so please message me if you'd like to be added.

Our new study is out on BioRXiv! tinyurl.com/pfcmap We (@carlenlab.bsky.social lab) mapped the mouse PFC using single-unit activity! We recorded ~23,000 neurons across cortical/subcortical regions and profiled spont. firing patterns to reveal what separates the PFC from other brain regions. 1/n

PhD project! For those interested in NeuroAI: "Using large scale neural network models to bridge the translational gap from animal models to human insights in autism spectrum and neurodevelopmental disorders" Apply here: www.ai4biomed.io/research/pro...

Ok, so I wanted to try my hand at building a starter pack too :-). This pack includes developers of tools and methods for electrophysiology (focused on extracellular recordings). Please let me know if I missed anyone! Also, we need more people from X to switch to fill this out! go.bsky.app/DFWsuTJ

Important paper! www.biorxiv.org/content/bior... Im not sure the Discussion fully delineates its radical implications. No more... * Place cells * Grid cells, splitter cells, border cells * Mirror neurons * Reward neurons * Conflict cells (continued)

First post on Bluesky, let’s share some websites offering many free illustrations for scientific figures 🖼️ 🧪 🌍 : scidraw.io bioart.niaid.nih.gov www.phylopic.org More well known but very nice though: www.freepik.com

Inspired by @hleisthen.bsky.social and @denizhanpak.bsky.social I've put together a starter pack for neuroethology (broadly defined). Follow these people if you're interested in learning about the mechanisms underlying animal behaviour. Suggestions welcome! go.bsky.app/T5JTFzE

We wrote a review on analysis methods for large-scale neural recordings www.science.org/stoken/autho... @marius10p.bsky.social #neuroscience 🧪🧠 Anything we missed? Reply w/ your fav method!

Fun to see this place coming a bit more alive! I tried my hand at a starter pack for neural engineering & computationally-leaning (systems) neuroscience. Super not exhaustive, so if you want to be added (or removed), just ping me. I'm still working on finding folks here. go.bsky.app/Ty3ftme

Comp neuro here: bsky.app/profile/aesa...

Hello! I am a postdoctoral researcher working at the intersection of machine learning and neuroscience. Looking forward to using this app. :-)