This is an incredibly moving thread.

The world may be horrible at the moment, but I am thrilled to share a preprint on our work to develop novel diagnostics and tools to study #Oropouche virus, (probably) the most important virus that you’ve never heard of: doi.org/10.1101/2025... Bluetorial follows 🟦🧵

@rorymulloy.bsky.social et al illuminate mechanism rewarding evolution of novel transcriptional start sites in SARS-CoV-2 during its adaptation to humans 👀. From: @corcoranlab.bsky.social www.biorxiv.org/content/10.1...

Pre-print is up! SARS-2 produces a truncated N protein to antagonize multiple antiviral pathways. A very collaborative project in the @corcoranlab.bsky.social with @nogasharlin.bsky.social, Danyel Evseev, and Max Bui-Marinos, and of course the boss Jenn Corcoran www.biorxiv.org/content/10.1...

Our newest work reveals that SARS-CoV-2 evolved to produce a truncated version of its N protein to antagonize antiviral responses. This 'mini' N, called N*M210, sequesters dsRNA, blocks interferon activation, defeats RNaseL & disassembles stress granules and p-bodies. www.biorxiv.org/content/10.1...