How do we update our predictions when our environment changes? The hippocampus rapidly integrates previously distinct sequences to support updated predictions. Proud of this work with Hannah Tarder-Stoll & @chrisbaldassano.bsky.social! www.biorxiv.org/content/10.1...

We are hiring for several research positions for this grant, starting early next year. Please reach out if you're interested! More details on the jobs here: devcompsy.org/wp-content/u...

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

🧠✨ Exciting new research alert! ✨🧠 Did you know that catecholamines can reduce choice history biases in perceptual decision-making? 🧐🔍 Paper: journals.plos.org/plosbiology/... With @donnerlab.bsky.social and @swammerdamuva.bsky.social

My first paper with @naoshigeuchida.bsky.social is finally out in @natcomms.nature.com ! rdcu.be/eACGf TL;DR: asymmetric learning rates can be induced by shifts in tonic dopamine giving rise to pessimistic/optimistic biases in agents or animals undergoing reinforcement learning .

Its a new term and a lot of us are preparing their lectures. I am a huge fan of online ways of teaching. And my student Joey Rudoler @jrudoler.bsky.social made a great online stats course. Shiny app and all. Modern take on stats. Thought some of you may appreciate.

Are you at @assc28.bsky.social #ASSC28? On Wednesday I will present a poster on the causal relationship between choice history biases and catecholamines (noradrenaline / dopamine). With @donnerlab.bsky.social et al.

Are you at @assc28.bsky.social #ASSC28? Later, @stijnnuiten.bsky.social will present exciting cross-species results on the interaction between latent behavioral states, pupil-linked arousal, and V1 activity. Great collab w/ @psterzer.bsky.social @svangaal.bsky.social @pennartz.bsky.social et al.

Thrilled to see our TinyRNN paper in @nature! We show how tiny RNNs predict choices of individual subjects accurately while staying fully interpretable. This approach can transform how we model cognitive processes in both healthy and disordered decisions. doi.org/10.1038/s415...

1/ New paper by Hame Park, (@AraziAyelet), Bharath Talluri, Marco Celotto, Stefano Panzeri, Alan Stocker & Tobias Donner published in Nature Communications – “Confirmation Bias through Selective Readout of Information Encoded in Human Parietal Cortex”: rdcu.be/etlR7. Here is a summary:

This is a super cool way of studying learning, effort, and foraging www.biorxiv.org/content/10.1...

Abstract rule learning promotes cognitive flexibility in complex environments across species www.nature.com/articles/s41... #neuroscience

We show that memantine selectively improves neural decoding of attended illusory Kanizsa triangles, revealing NMDA receptor-dependent enhancement of feedback processing. elifesciences.org/articles/100... Thanks to Samuel Noorman @fahrenfort.bsky.social @timostein.bsky.social Jasper Zantvoord

Pulsed taVNS elicits pupil dilation. However, if sham feels as intense, there is not much left. Based on our comparatively large sample (94 participants, single-blind crossover), we show that a highly variable sham response explains this. #neuroskyence 🩺 www.biorxiv.org/content/10.1...

Hard agree. Great article on a timely issue by @neuralreckoning.bsky.social for @thetransmitter.bsky.social

To celebrate the defence of my PhD, and thanks to @ibbamsterdam.bsky.social, I will host a symposium titled "Vision as prediction: learning, action, and biases" on June 6. Program, registration and more information here: bit.ly/43reOgR

New PhD vacancy in my lab: werkenbij.uva.nl/en/vacancies.... The position involves interacting with patients, so *proficiency in Dutch* is essential. Please spread the word!

⚠️ Come see our new preprint, in which we (@degeelab.bsky.social, Jasper Zantvoord, @psterzer.bsky.social, @fahrenfort.bsky.social & @svangaal.bsky.social) show that phasic (task-evoked) and tonic (baseline) arousal distinctly shape human decision bias! (1/6) dx.doi.org/10.21203/rs....

THIS IS ONE NEURON! Jaw dropping. It distributes a particular neurotransmitter (norepinephrine) across the mouse brain; it’s a locus coeruleus neuron. @jeremiahycohen.bsky.social and colleagues at the @alleninstitute.bsky.social are using new biotech to see things never seen before.

Excited to share my PhD paper! In it, we use targeted 2-photon optogenetic stimulation to determine how V1 activity is read-out in a detection task. We found that network influence, not visual coding properties, predicted the impact of ensembles on behavior - contradicting our expectations (1/5).

I recently had the great pleasure of interviewing Michael Bruchas about an absolutely banger recent paper from his group that tracked down cells in the brainstem that subtlety and precisely control the output of the locus coeruleus. Check out my interview here. I hope you like it as much as I did!

First post on an exciting new manuscript online today @natneuro.nature.com - in collab with @lucinauddin.bsky.social and Catie Chang. We take a fresh look at the physiological dynamics associated with the global signal 🧠 ... www.nature.com/articles/s41... Read here: rdcu.be/ek01F

A wonderful day for science, to see the (peri) #LC in all its glory. A ginormous effort from all involved, and a fantastic resource for the field. Chapeau 🎩 🧠 🔵 www.nature.com/articles/s41...

An open letter supporting the international bachelor’s psychology programs threatened for cuts. Proceeding with these cuts would damage some of the most important and impactful psychology departments globally. #supportdutchpsychology openletter.earth/against-lang...

My lab is looking for a PhD candidate, in collaboration with ​Bernhard Englitz​'s lab. www.ru.nl/en/working-a...

First preprint from our lab! An @jerlich.bsky.social collaboration We developed novel frameworks to study multi-agent decisions in mice. Mice flexibly shift their decision preference under social competition, by integrating real-time self and opponent information! www.biorxiv.org/content/10.1...

I am so happy—this is the first 1st author paper I have written, since the cancer diagnosis of my late wife seven years ago. 📑 PAPER ALERT: "Beyond binding: from modular to natural vision" in Trends in Cognitive Sciences (2025) sciencedirect.com/science/arti...

Excited to share my latest work just out in @pnas.org! This NIH MOSAIC K99-funded project identifies a top-down cortical circuit—from cingulate to auditory cortex—that supports auditory perceptual performance in challenging listening conditions: www.pnas.org/doi/10.1073/...

I'm excited to share that the last chapter of my PhD thesis is now published in Nature! 🍾 What drives serotonin neurons? We think it's the expectation of future reward and --- critically --- how fast this expectation is increasing. 📈 doi.org/10.1038/s415... 1/6

Our "I would have seen it if it were there" paper — a collaboration with @ranimo.bsky.social and @clarepress.bsky.social — is now out in Psych. Review. There’s a lot in this paper, but here are what I see as the 3 main takeaways: psycnet.apa.org/fulltext/202...

1/7 Our paper on individual variability in decision-making is finally out in @nature.com! Inspired by the classic work by Mante and Sussillo, we trained many rats to solve context-dependent decision-making, and we found that different brains use different neural mechanisms to solve the same task!

Neuron Slow cortical dynamics generate context processing and novelty detection www.cell.com/neuron/abstr...

My lab is looking for a computational neuroscience postdoctoral researcher: www.ru.nl/en/working-a... Come join us at the @dondersinst.bsky.social!

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

Happy to have this published …https://www.science.org/doi/10.1126/sciadv.adr6698

I am very excited to share our new preprint together with @Isabella Goodwin, @Kelly Diederen, @Emily Hird, @veithweilnhammer.bsky.social, and @Marta Garrido! Where does predictive processing stand in psychosis research - revisiting Sterzer et al (2018) seven years later. 🧠🔍? osf.io/preprints/ps...

New preprint: "The geometry of the neural state space of decisions", work by Mauro Monsalve-Mercado, buff.ly/42wVHD5. Surprising results & predictions! (Thread) We analyze neuropixel population recordings in macaque area LIP during a reaction time, random-dot motion 1/

Excited to have our new paper out in @cpsyjournal.bsky.social 🎉✨ with my amazing co-authors @christopherjwhyte.bsky.social @hohwy.bsky.social We develop an active inference model of the optimism bias to model development, belief updating and optimistic action. cpsyjournal.org/articles/10....

A new Python toolbox called HSSM simplifies working with Hierarchical Sequential Sampling Models (HSSMs) to understand how we accumulate evidence and make choices. Built on PyMC, Bambi, & ArviZ. Check it out! #cognitivescience #python #decisionmaking edspace.american.edu/openbehavior...

New layer-fMRI manuscript describing the predictive processing across layers of auditory areas. By Lonike Faes et al. biorxiv.org/lookup/doi/1...

Does the culture you grow up in shape the way you see the world? In a new Psych Review paper, @chazfirestone.bsky.social & I tackle this centuries-old question using the Müller-Lyer illusion as a case study. Come think through one of history's mysteries with us🧵(1/13):

Fresh out: a short review article where I give an overview of different ways that across-trial temporal structure is helpful in understanding cognitive models of decision-making osf.io/preprints/ps...

I would like to share new work that focusses on non-invasive manipulations of (noradrenergic) arousal during human cognitive behavior.

At #SfN24 and interested in #misophonia or more generally in objective measures (#pupillometry) of disordered perception? Come check out my poster:

New preprint: Sound-evoked pupil dilation quantifies misophonic symptoms. osf.io/preprints/os...

Mototaka Suzuki and I are currently recruiting a PhD student to work on the cognitive and systems neuroscience of belief updating. Deadline: 31 March. Please retweet! www.academictransfer.com/en/337965/ph...

A really fun experimental-computational collaboration with colleagues Lola Beerendonk, Jorge Mejias, Simon van Gaal and others, to understand the century-old psychological law of Yerkes and Dodson. Full paper @PNASnews: www.pnas.org/doi/10.1073/... Press release: www.uva.nl/en/content/n...

I'm elated to share my PhD keystone paper published @PNAS www.pnas.org/doi/10.1073/... I've poured my heart & soul into this project since 2016 (8 yrs!) & I'm happy to introduce the Effort Foraging Task to the world #CognitivePsychology #Motivation #Effort #Foraging #DecisionMaking 🧵

Super thrilled to share: 🧠 "Brainstem fMRI signaling of surprise across different types of deviant stimuli" now published in Cell Report with Franck Mauconduit, Alexis Amadon, @degeelab.bsky.social, Tobias Donner, & Florent Meyniel. www.sciencedirect.com/science/arti... A quick thread:

Many researchers in cognitive neuroscience and deep learning seem to assume that inference in the brain is hierarchical.  Our new Nature Reviews Neuroscience paper questions this assumption and proposes the shallow brain hypothesis. #neuroskyence #brain www.nature.com/articles/s41...